Clinical trials: Delirium, completed
Delirium
DElirium prediCtIon in the intenSIve Care Unit: Head to Head comparisON of Two Delirium Prediction Models
Currently, two ICU delirium prediction models are available: the PRE-DELIRIC model and the early prediction model (E-PRE-DELRIC).
- Trial name
- DECISION (NCT02518646)
- Where
- Netherlands
- Volunteers
- 2,500 people
- Sponsor
- Radboud University Medical Center
Emergence Delirium
Effect of Sugammadex vs. Neostigmine/Glycopyrrolate on Pediatric Emergence Delirium in Sevoflurane-rocuronium Anesthesia
The aim of this study is to investigate the effect of sugammadex vs. a conventional acetylcholinesterase inhibitor, neostigmine on emergence delirium (ED) during sevoflurane-rocuronium anesthesia in pediatric patients…
- Trial name
- NCT03229486
- Testing
- Sugammadex Injection [Bridion], Neostigmine+Glycopyrronium
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Pusan National University Yangsan Hospital
Postoperative Delirium, Elderly Patient
Diagnosis, Incidence and Consequences of PACU-Delirium
This study aims to 1. determine sensitivity and specificity of the Confusion Assessment Method for Postanesthesia Care Unit (CAM-PACU) 2.
- Conditions
- Postoperative Delirium, Elderly Patient, Cognitive Decline
- Trial name
- PADE-DIC (NCT04978870)
- Where
- Germany
- Volunteers
- 450 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Critical Illness, Respiratory Failure
CONFOCAL-2 Interventional Pilot Study
This study is designed to assess the feasibility of identifying and administering individualized blood pressure targets early critical illness.
- Conditions
- Critical Illness, Respiratory Failure, Shock, Delirium
- Trial name
- NCT07296029
- Testing
- Autoregulation-based precision blood pressure management
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Queen's University
Emergence Delirium
Incidence of Emergence Delirium in the PACU
Emergence delirium (ED) is serious complication in the postoperative period in paediatric anaesthesia, reported incidence is 20-60%.
- Trial name
- PACUDEL (NCT04531020)
- Testing
- PAED measurement
- Where
- Czechia
- Volunteers
- 1,421 people
- Sponsor
- Brno University Hospital
Confusion, Delirium
Validation of a French Version of the Confusion Assessment Method (CAM)
To validate the French version of the CAM, a multicenter diagnostic study will be conducted. The principle of this study is identical to the study of Inouye which initially validated the CAM in 1990.
- Trial name
- NCT01775982
- Testing
- Psychiatric evaluation, Geriatric evaluation
- Where
- 8 sites in France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Postoperative Delirium
Remimazolam vs. Propofol: Impact on Postoperative Delirium in Neurosurgical Patients
The investigator aimed to evaluate the incidence of postoperative delirium after remimazolam-based total intravenous anesthesia (TIVA) compared to the propofol-based TIVA in patients undergoing neurosurgery.
- Trial name
- NCT06115031
- Testing
- Remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 696 people
- Sponsor
- Samsung Medical Center
Cardiac Surgery, Cardiopulmonary Bypass
Comparison of Remowell 2 and Inspire on Delirium and Cognitive Dysfunction
Age is no longer an absolute contraindication to cardiac surgery therefore there is often need for combined interventions (double valve repair/replacement, or coronary artery bypass graft and valve repair/replacement) with…
- Trial name
- CRIDD (NCT04062396)
- Testing
- Eurosets REMOWELL 2 oxygenator, LivaNova INSPIRE oxygenator
- Where
- Italy
- Volunteers
- 154 people
- Sponsor
- Maria Cecilia Hospital
Delirium, Falls
Prophylactic Environmental Management of Delirium
Delirium is a complex neuropsychiatric syndrome with an acute onset and fluctuating course which is presented in 15 to 20% of patients admitted to general wards.
- Trial name
- MAPDI (NCT01356810)
- Testing
- Environmental Intervention, Standard Care
- Where
- Chile
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Surgery--Complications, Anesthesia Complication
THRIVE Feasibility Trial
To evaluate the feasibility of a pragmatic, large scale, comparative effectiveness, randomized evaluation of patient experience of intravenous propofol versus inhaled volatile anesthesia.
- Conditions
- Surgery--Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia Emergence Delirium
- Trial name
- THRIVE (NCT05346588)
- Testing
- Anesthetic technique Propofol TIVA, Anesthetic technique inhaled agent
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- Washington University School of Medicine
Delirium, Postoperative
Perioperative Risk Factors for Postoperative Delirium in Children
Despite recent advances in postoperative delirium research, the proportion of children with postoperative delirium is still high.
- Trial name
- NCT01032161
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Huazhong University of Science and Technology
Postoperative Delirium
Effect of Electroacupuncture on the Incidence of Postoperative Delirium in Elderly Patients Undergoing the Major Surgery
1. Title: Effect of electroacupuncture on the incidence of postoperative delirium in elderly patients undergoing the major surgery. 2. Research center: Multicenter 3.
- Trial name
- NCT03606941
- Testing
- electroacupuncture treatment
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- Tianjin Nankai Hospital
Tonsillitis
Comparison of Dexmedetomidine and Midazolam for Prevention of Emergence Delirium in Children
Emergence delirium is a common complication in children after anesthesia. The incidence of emergence delirium is reported upto 50%.
- Trial name
- NCT03337672
- Testing
- Dexmedetomidine, Midazolam
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eunah Cho, MD
Stress Response
Effect of Dexmedetomidine on Stress Response and Emergence Agitation During Laparoscopic Surgery
Emergence agitation is a post-anesthetic phenomenon that develops in the early phase of general anesthesia recovery, and is characterized by agitation, confusion, disorientation, and possible violent behavior.
- Trial name
- NCT02917018
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Postoperative Delirium
Intraoperative Dexmedetomidine Use, MMP-8, and Postoperative Delirium After Cardiac Surgery With Cardiopulmonary Bypass
This observational study evaluated the association between intraoperative dexmedetomidine use and postoperative delirium (POD) in adults undergoing cardiac surgery with cardiopulmonary bypass (CPB).
- Trial name
- NCT07759297
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 5,688 people
- Sponsor
- Shusheng Li
Parkinson Disease, Deep Brain Stimulation
Association Between Fibrinogen-to-albumin Ratio and Delirium After Deep Brain Stimulation Surgery in Parkinson's Disease
Postoperative delirium (POD) remains one of the most common neuropsychiatric complications after deep brain stimulation (DBS) surgery.
- Conditions
- Parkinson Disease, Deep Brain Stimulation, Postoperative Delirium
- Trial name
- NCT05833308
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Changhai Hospital
Delirium, ICU
PupillOmetry for Prediction of DelirIUM
Delirium in intensive care unit (ICU) is a serious event. It is associated with short-term complications (agitation, self-extubation, accidental removal of catheters, prolonged length of stay and ventilation), excess mortality…
- Trial name
- PODIUM (NCT05248035)
- Testing
- Adult patient hospitalized in ICU
- Where
- France
- Volunteers
- 209 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postoperative Delirium
Postoperative Delirium in Elderly Patients Undergoing Major Non-Cardiac Surgery in Singapore
The primary aim of this study is to investigate the incidence, risk factors and sequelae of postoperative delirium in elderly patients undergoing major non-cardiac surgery in Singapore.
- Trial name
- NCT04330950
- Testing
- Neurocognitive tests
- Where
- 4 sites in Singapore
- Volunteers
- 98 people
- Sponsor
- National University Hospital, Singapore
Delayed Emergence From Anesthesia, Postoperative Delirium
Trajectory of Recovery in the Elderly
The purpose of this study is to understand how elderly individuals regain their cognitive skills following general anesthesia. The investigators will compare an age stratified group of volunteers who will be evaluated with a…
- Conditions
- Delayed Emergence From Anesthesia, Postoperative Delirium, Postoperative Cognitive Dysfunction
- Trial name
- TORIE (NCT02275026)
- Testing
- Functional magnetic resonance imaging
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
High Risk Non-cardiac Surgery, Death
Cerebral Oximetry and Perioperative Outcome in Non-Cardiac Surgery
Cerebral desaturations occur frequently in patients undergoing non-cardiac surgery. The definition of what constitutes a cerebral desaturation, the incidence of the phenomenon, the association between desaturations and…
- Conditions
- High Risk Non-cardiac Surgery, Death, Delirium, Kidney Injury
- Trial name
- NCT01838733
- Testing
- Observational study
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- University of Manitoba