Clinical trials: Delirium, completed
Delirium and Insomnia
Diagnosis of Delirium and Assessment of Sleep Quality in Patients in the Anesthesia and Intensive Care Unit
This study included patients in the anesthesia and intensive care unit (ICU). Over half the patients did not experience delirium.
- Trial name
- delirium sleep (NCT06699004)
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Lumbar Spine Disease
Deep Neuromuscular Block on Postoperative Delirium in Lumbar Surgery
The effect of deep neuromuscular blockade (NMB) during spine surgery reduced postoperative pain and bleeding in recent studies. Therefore by reducing these two factors, which were the contributing factors for postoperative…
- Trial name
- NCT05453929
- Testing
- Rocuronium for deep NMB, Rocuronium for moderate NMB
- Where
- South Korea
- Volunteers
- 230 people
- Sponsor
- Korea University Guro Hospital
Sleep Deprivation, Sleep
Sleep Headphones and HDU: a Novel Intervention and Sound Evaluation
It is well established that patients sleep poorly in the Intensive Care Unit (ICU), and excessive noise is considered to be a modifiable cause of this.
- Trial name
- SHH: Noise! (NCT03774212)
- Testing
- Active noise cancelling headphones
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Edinburgh
Postoperative Delirium
Incidence and Perioperative Factors Associated With Postoperative Delirium
With the increasing number of advanced surgical operations being done annually, including the elderly, the risk of developing postoperative delirium is potentially high.
- Trial name
- iPOD (NCT02904928)
- Where
- Uganda
- Volunteers
- 437 people
- Sponsor
- Makerere University
Delirium
A Family Intervention for Delirium Prevention
To address the feasibility of implementing a randomized, educational intervention to prevent delirium, directed at family members of hospitalized older (70 years of age or older) medical in-patients.
- Trial name
- NCT01998997
- Testing
- Family educational intervention
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Sleep Deprivation, Delirium
Sleep/Wake Protocol Implementation to Improve Sleep Quality in the ICU
The purpose of this study is to analyze a multi-component sleep/wake protocol for optimization of environmental factors (noise, light, nursing activities) as well as non-environmental factors (pain, mechanical support devices…
- Trial name
- NCT03313115
- Testing
- Sleep/Wake Protocol
- Where
- United States
- Volunteers
- 685 people
- Sponsor
- University of Utah
Postoperative Delirium
Postoperative Delirium in Elderly Patients Undergoing Major Non-Cardiac Surgery in Singapore
The primary aim of this study is to investigate the incidence, risk factors and sequelae of postoperative delirium in elderly patients undergoing major non-cardiac surgery in Singapore.
- Trial name
- NCT04330950
- Testing
- Neurocognitive tests
- Where
- 4 sites in Singapore
- Volunteers
- 98 people
- Sponsor
- National University Hospital, Singapore
Post-Operative Delirium, Hip Fracture
Post-operative Haloperidol Versus Placebo for Prevention of Post-operative Delirium After Acute Hip Surgery
In this study the investigators want to determine if treatment with haloperidol direct post-operatively after acute hip surgery in high risk patients protects against developing a post-operative delirium.
- Trial name
- NCT00250237
- Testing
- Haloperidol
- Where
- Netherlands
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Bronovo Hospital
Emergence Delirium
Preoperative Chronotype and Emergence Delirium in the Elderly
Emergence delirium (ED) is a prevalent and severe postoperative complication in elderly surgical patients. It can occur at any perioperative stage but most frequently develops during or immediately after emergence from general…
- Trial name
- NCT07722481
- Testing
- the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU)
- Where
- China
- Volunteers
- 235 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Noise in the ICU, Sleep Quality in Adult ICU Patients
Noise in the Intensive Care Unit
Rationale: Sound levels in the Intensive Care Unit are frequently reported to exceed the recommended levels. It is plausible to assume that this causes sleep disturbance in the patients on the ICU.
- Trial name
- NCT01826799
- Where
- 6 sites in Netherlands
- Volunteers
- 75 people
- Sponsor
- Jeroen Bosch Ziekenhuis
Emergence Agitation
Melatonin for Pediatric Emergence Agitation
efficacy of melatonin premedication on emergence agitation in children undergoing herniorrhaphy surgeries
- Trial name
- NCT05223010
- Testing
- Melatonin 5 MG/15 ML Oral Solution 0.05 mg/kg, Melatonin 5 MG/15 ML Oral Solution 0.2mg/kg, Melatonin 5 MG/15 ML Oral Solution 0.4mg/kg
- Where
- Egypt
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Geriatric Patient Care Improvement, EEG Data Analysis
Anesthetic Agent Titration With EEG Wave Analysis
Several studied shown that when general anesthesia is applied under BIS guidance, anesthetic doses are reduced. Additionally it has been found that the risk of postoperative delirium (POD) is reduced and postoperative recovery is…
- Trial name
- NCT07266727
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University
Postoperative Cognitive Dysfunction, Delirium, Postoperative
Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass
Neurological dysfunction either transient or permanent is a major cause of morbidity and mortality after cardiopulmonary bypass, and cognitive dysfunction is more frequent in cardiac surgery than in non-cardiac procedures.
- Trial name
- NCT07000461
- Testing
- Transcranial Doppler measurement of the middle cerebral artery
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Cognitive Dysfunction, Postoperative Delirium
Electroencephalographic Biomarker to Predict Acute Post-operatory Cognitive Dysfunction
Acute post-operatory cognitive dysfunction states are one of the most important complications in older patients after surgery. Two acute cognitive dysfunctions have been described: postoperative delirium (PD) and postoperative…
- Trial name
- NCT04214496
- Testing
- Sedline
- Where
- 2 sites in Chile
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Chile
Epilepsy, Depression
Measuring Blood Flow in the Brain After Epileptic Activity
In this clinical trial, postictal phenomena (i.e., headache, delirium) will be investigated after administration of acetaminophen and nimodipine in depressed patients receiving electroconvulsive therapy (ECT).
- Conditions
- Epilepsy, Depression, Postictal Delirium, Electroconvulsive Therapy
- Trial name
- SYNAPSE (NCT04028596)
- Testing
- Paracetamol, Nimotop
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Rijnstate Hospital
Emergence Agitation
Effect of Dexmedetomedine in Subtenon's Block on Emergence Agitation in Pediatric Strabismus Surgery
The study is conducted to evaluate the effects of dexmedetomedine in subtenon's block in conjunction to general anesthesia under sevoflurane anesthesia on emergence agitation, intraoperative hemodynamic stability, postoperative…
- Trial name
- NCT04485273
- Testing
- Laryngeal Mask Airway, Sevoflurane, Subtenon's Block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sameh Fathy
Post-Intensive Care Syndrome
Collaborative Assessment of ICU Recovery Needs
The primary purpose of this study is to better understand the impact of the Society of Critical Care Medicine (SCCM) THRIVE Collaboratives on patients, their families and clinicians.
- Trial name
- CAIRN (NCT03513289)
- Testing
- Patient, Carer, and Clinician Interviews
- Where
- 2 sites in United States, Australia
- Volunteers
- 66 people
- Sponsor
- Vanderbilt University Medical Center
Delirium, Aging
MIND-ICU Study: Delirium and Dementia in Veterans Surviving ICU Care
This will be the first large cohort study to define the epidemiology of and identify modifiable risk factors for long-term CI and functional deficits of ICU survivors.
- Conditions
- Delirium, Aging, Dementia
- Trial name
- NCT00400062
- Where
- 3 sites in United States
- Volunteers
- 800 people
- Sponsor
- VA Office of Research and Development
Delirium
Incidence, Severity and Treatment of Delirium in Cardiac Surgery Patients: A Before-after Study
Delirium is a common yet under diagnosed condition in hospitalized patients, and the incidence have not previously been described in Danish cardiac surgery patients.
- Trial name
- NCT01774240
- Testing
- systematic screening and treatment of delirium
- Where
- Denmark
- Volunteers
- 230 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Tonsillectomy
Dexmedetomidine as a Rapid Bolus in Children for Emergence Agitation
To Determine The Efficacy of a Rapid Bolus Injection of Dexmedetomidine on the Incidence of Emergence Agitation in Anesthetized Children and the Cardiovascular Profile of a Rapid Bolus Injection of Dexmedetomidine.
- Trial name
- NCT01528891
- Testing
- Dexmedetomidine
- Where
- 2 sites in United States
- Volunteers
- 418 people
- Sponsor
- Peter Davis