Clinical trials: Delirium, completed
COVID-19, Delirium
HD-Tdcs and Pharmacological Intervention For Delirium In Critical Patients With COVID-19
The goal of this clinical trial Is conducted to evaluate the efficacy and safety of active or sham HD-tDCS in combination with dexmedetomidine in patients with moderate to severe ARDS due to COVID-19 with delirium in intensive…
- Conditions
- COVID-19, Delirium, Critical Illness
- Trial name
- COVID-19 (NCT05963958)
- Testing
- Active HD-tDCS
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Suellen Andrade
Delirium, Surgery--Complications
Predictive Factors and Complications of Delirium
The objective of this research was to determine the incidence, predisposing and triggering factors of delirium following cardiac surgery and its consequences within 30 days of surgery and during a 12-18-month follow-up in older…
- Conditions
- Delirium, Surgery--Complications, Age Problem
- Trial name
- NCT03246165
- Testing
- Cardiac surgery
- Volunteers
- 173 people
- Sponsor
- University of Sao Paulo
Cardiac Surgery, Cardiopulmonary Bypass
Low-dose Dexmedetomidine and Postoperative Delirium After Cardiac Surgery
Delirium is an acutely occurred and fluctuating cerebral dysfunction characterized with inattention, altered consciousness, cognitive decline and/or abnormal perception.
- Conditions
- Cardiac Surgery, Cardiopulmonary Bypass, Dexmedetomidine, Delirium
- Trial name
- NCT03624595
- Testing
- Dexmedetomidine
- Where
- 2 sites in China
- Volunteers
- 504 people
- Sponsor
- Dong-Xin Wang
Post Operative Delerium
The Effect of Dexmedetomidine Infusion Alone Versus the Combination of Dexmedetomidine and Melatonin on Reduction of Post-operative Delirium (POD) After Open Brain Surgeries
The aim of this study is to illuminate the effect of combination of dexmedetomidine and oral melatonin versus the use of dexmedetomidine infusion alone on the improving of post-operative delirium (POD) on patients undergoing open…
- Trial name
- NCT07475156
- Testing
- Dexmedetomidine (DEX), Melatonin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Insomnia, Sleep Fragmentation
Suvorexant and Sleep/Delirium in ICU Patients
Investigators will evaluate the efficacy of postoperative oral suvorexant treatment on nighttime wakefulness after persistent sleep onset (WASO) among adult cardiac surgical patients recovering in the cardiac intensive care unit…
- Conditions
- Insomnia, Sleep Fragmentation, Sleep Initiation and Maintenance Disorders, Postoperative Delirium
- Trial name
- NCT04092894
- Testing
- Suvorexant 20 mg
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Beth Israel Deaconess Medical Center
Delirium
Delirium, Electroencephalographic Alterations and Cortical Spreading Depression (CSD) in Critical Illness
Delirium in the intensive care unit is an acutely developed brain dysfunction affecting up to 80 % of patients. It is associated with significantly increased morbidity and mortality during admission and post-discharge.
- Trial name
- NCT01980251
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Delirium, Critical Illness
Pilot Study of Haloperidol to Treat Critical Illness Delirium
The goal of this study is to determine whether haloperidol reduces the time on the breathing machine in critically ill patients with delirium.
- Trial name
- NCT00429676
- Testing
- Haloperidol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Regional Anaesthesia, Postoperative Delirium (POD)
Association of Transversus Abdominis Plane Block (TAPB) with Postoperative Delirium (POD) in Elderly Patients Undergoing Major Gastrointestinal Surgery
Postoperative delirium can increase postoperative adverse reactions and prognosis in elderly patients undergoing gastrointestinal surgery.
- Conditions
- Regional Anaesthesia, Postoperative Delirium (POD), Transversus Abdominis Plane Block (TAP Block)
- Trial name
- NCT06829108
- Volunteers
- 5,220 people
- Sponsor
- Chinese PLA General Hospital
Delirium, Alzheimer Disease
Improving the Recovery and Outcome Every Day After the ICU
Primary Specific Aim: Determine the effect of the combined physical exercise and cognitive training on the cognitive function of ICU survivors aged 50 and older.
- Trial name
- IMPROVE (NCT03095417)
- Testing
- Physical Exercise Intervention, Cognitive Training Intervention, Stretching Control
- Where
- 6 sites in United States
- Volunteers
- 249 people
- Sponsor
- Indiana University
Alzheimer's Disease, Dementia
A Single Site, Randomized, Double-blind, Placebo Controlled Trial of NIC5-15 in Subjects With Alzheimer's Disease
The purpose of this study is to evaluate the safety and efficacy of NIC5-15 in the treatment of Alzheimer's Disease.
- Trial name
- NCT01928420
- Testing
- Drug: NIC5-15
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Humanetics Corporation
CABG
Effect of a Preoperative Video Education Program on ICU Delirium After CABG (VIDEO-CABG Trial)
The goal of this clinical trial is to evaluate the effect of a preoperative video-based educational program on postoperative outcomes in adult patients undergoing coronary artery bypass graft (CABG) surgery.
- Trial name
- VIDEO-CABG (NCT07570420)
- Testing
- Video-Based Educational Program
- Where
- Jordan
- Volunteers
- 220 people
- Sponsor
- University of Jordan
Delirium, Cardiac Disease
Reducing Delirium After Cardiac Surgery: A Multifaceted Approach Of Perioperative Care
The objective of this study is to reduce the incidence of postoperative delirium after cardiac surgery in the elderly patient. This proposal is a clinical trial designed to reduce delirium in patients undergoing cardiac surgery…
- Trial name
- NCT01378741
- Testing
- Propofol, Dexmedetomidine
- Where
- Canada
- Volunteers
- 185 people
- Sponsor
- University Health Network, Toronto
Delirium, Respiratory Depression
Acupuncture for Sedation in the Intensive Care Unit (ICU)
BACKGROUND Many patients in the trauma intensive care unit (TICU) require mechanical ventilation and sedation or anxiolysis. Mechanical ventilation means that a machine is helping a patient breathe if he can't breathe on his own.
- Conditions
- Delirium, Respiratory Depression, Overmedication
- Trial name
- NCT01362270
- Testing
- Verum Acupuncture
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Oregon Health and Science University
Postoperative Delirium
Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial
The purpose of this study is to find out whether postoperative delirium can be more properly prevented by the combination of determined preventive agents in past studies.
- Trial name
- PRIDe (NCT02433041)
- Testing
- Haloperidol, Ketamine, Haloperidol + Ketamine
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Noise Exposure, Sedative Withdrawal Delirium
Sound Levels in the Pediatric Cardiac Critical Care Unit and Their Correlation With Sedation Administration, Delirium Scores and Patient Heart Rate
There is limited data regarding sound levels and burden in the pediatric cardiac critical care unit and how this compares with WHO standards.
- Conditions
- Noise Exposure, Sedative Withdrawal Delirium, Sedative Toxicity
- Trial name
- NCT04777695
- Testing
- Decibel Monitor
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Children's National Research Institute
Delirium
Dexmedetomidine Versus Propofol for Prolonged Sedation in Critically Ill Trauma and Surgical Patients
The purpose of this study is to assess the efficacy of dexmedetomidine versus propofol for prolonged sedation in trauma and surgical patients.
- Trial name
- NCT02548923
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
Postoperative Delirium
Preoperative Distress and Postoperative Delirium in Elderly Patients Undergoing Major Orthopedic Surgery
Postoperative delirium is a common and serious complication in elderly patients undergoing major orthopedic surgery and is associated with increased morbidity, prolonged hospital stay, and higher healthcare costs.
- Trial name
- NCT07512752
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Emergence From Anesthesia, Mechanical Ventilation
Controlled Ventilation During Anesthetic Emergence
Absolutely - for a ClinicalTrials.gov-style Brief Summary, I'd keep it simple and patient-friendly like your example: The goal of this clinical trial is to learn whether maintaining controlled mechanical ventilation during…
- Trial name
- NCT07853547
- Testing
- Controlled/Full-Support Mechanical Ventilation During Emergence
- Where
- Saudi Arabia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz Medical City
PREOPERATIVE SLEEP QUALITY ON POSTOPERATIVE DELIRIUM
Preoperative Sleep Quality and Postoperative Delirium
Background: Delirium is a neurocognitive illness that has lately been connected to sleep difficulties. It is a stressful condition. is still not fully understood.
- Trial name
- NCT06273358
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Konya City Hospital
Delirium on Emergence
Post Extubation Delirium and End-tidal Sevoflurane Concentration
The purpose of this study is to determine whether the incidence of emergence delirium will be reduced when end-tidal concentration of sevoflurane decreases.
- Trial name
- NCT02489734
- Testing
- sevoflurane
- Volunteers
- 109 people
- Sponsor
- Children's Hospital of Fudan University