Clinical trials: Delirium, completed
Delirium
Thiamine Administration and Prevalence of Delirium in the Intensive Care Unit: A Before-after Study
Delirium is a very common condition among ICU-admitted patients, and its prevalence is estimated between 30-40%. Delirium is associated with increased morbidity and mortality and future cognitive decline, along with increased…
- Trial name
- NCT04214106
- Testing
- intravenous Thiamine
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Meir Medical Center
Delirium, Critical Illness
Pain Assessment in the Intensive Care Unit
Pain assessment using self-report scales (Visual Analogue Scale, Numerical Rating Scale), is recommended in the general population, however it is not always possible in patients with altered neurological status such as sedated…
- Trial name
- NCT01628185
- Testing
- Repositioning
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago
Delirium
Delirium Reduction by Volatile Anesthesia in Cardiac Surgery
Parallel group, prospective, randomized, controlled, single-blinded trial. The aim of our study is to test the hypothesis that volatile anesthesia would reduce the incidence of early postoperative delirium in patients undergoing…
- Trial name
- DELICATE (NCT03729011)
- Testing
- Volatile agent, Propofol
- Where
- 5 sites in Russia
- Volunteers
- 405 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Child, Anesthesia Morbidity
A Study on the Effects of Midazolam on Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery
Sevoflurane with its rapid induction and emergence, hemodynamic stability, and nonirritating airway properties, has acquired widespread acceptance in children.
- Conditions
- Child, Anesthesia Morbidity, Delirium on Emergence
- Trial name
- NCT01680471
- Testing
- Midazolam 0.03mg/kg, Midazolam 0.05mg/kg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Anam Hospital
Delirium
Incidence, Severity and Treatment of Delirium in Cardiac Surgery Patients: A Before-after Study
Delirium is a common yet under diagnosed condition in hospitalized patients, and the incidence have not previously been described in Danish cardiac surgery patients.
- Trial name
- NCT01774240
- Testing
- systematic screening and treatment of delirium
- Where
- Denmark
- Volunteers
- 230 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Delirium
pRophylactic halopEriDol Use for Delirium in iCu patiEnts With a High Risk for Delirium
The aim of this study is to determine the effects of a low dosage of prophylactic haloperidol in patients with a high risk to develop delirium, defined by an expected ICU length of stay of >1 day.
- Trial name
- REDUCE (NCT01785290)
- Testing
- Haloperidol 1 mg/q8h, Haloperidol 2 mg/q8h
- Where
- Netherlands
- Volunteers
- 1,800 people
- Sponsor
- Radboud University Medical Center
Emergence Agitation
Preemptive Intravenous Micro-dose Dexmedetomidine to Prevent Emergence Agitation in Adult Patients Undergoing Septoplasty Surgeries
This prospective randomized controlled study will be conducted to evaluate the effect of preoperative single, micro-dose of dexmedetomidine (0.3μg/kg) on the incidence and severity of EA in adults undergoing Septoplasty surgeries
- Trial name
- NCT07302815
- Testing
- Dexmedetomidine, Saline
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Delirium, Dementia, Amnestic, Cognitive Disorders, Memory Disorders
The Effects and Cost-Effectiveness of an Integrated Multidisciplinary Approach for Psychogeriatric Patients
The purpose of this study is to determine the effects and cost-effectiveness of a Diagnostic Observation Center for PsychoGeriatric patients (DOC-PG).
- Trial name
- NCT00402311
- Testing
- DOC-PG: integrated multidisciplinary assessment, Usual care: assessment by GP or one of the regional services
- Where
- Netherlands
- Volunteers
- 216 people
- Sponsor
- Maastricht University Medical Center
Delirium, Pediatric Disorder
Emergence Delirium in Children for Magnetic Resonance Imaging
Sedation or anaesthesia is necessary to be able to perform magnetic resonance imaging (MRI) on children who cannot keep still or are uncooperative, and thus the targets of maximum patient safety, successful imaging, and the…
- Conditions
- Delirium, Pediatric Disorder, Anesthesia
- Trial name
- NCT04816344
- Testing
- Outpatient Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Turkiye Yuksek Ihtisas Education and Research Hospital
Delirium
Efficacy of Melatonin in Decreasing the Incidence of Delirium in End of Life Patients
The purpose of this study is to determine if melatonin administration to end-of-life patients is effective in preventing the development of delirium compared with those who do not receive this treatment.
- Trial name
- NCT02536417
- Testing
- Melatonin, Sugar pill
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Fraser Health
Delirium, Critical Illness
The EARLY DELTA Trial
Rationale: Delirium is a type of acute encephalopathy that is triggered by an underlying somatic disorder. Patients experience disturbances in attention, alertness and other cognitive functions.
- Conditions
- Delirium, Critical Illness, Acute Encephalopathy
- Trial name
- EARLY DELTA (NCT05403268)
- Testing
- DeltaScan
- Where
- 2 sites in Netherlands
- Volunteers
- 131 people
- Sponsor
- Thomas Ottens
Coronary Artery Bypass, Delirium
Organ Protection for Coronary Artery Bypass Graft (CABG): Propofol Versus Desflurane
Background: Different anaesthetic agents have been shown to have different protective effects upon heart, brain and renal function under ischaemic conditions (oxygen starvation).
- Conditions
- Coronary Artery Bypass, Delirium, Dementia, Amnesia
- Trial name
- NCT00400790
- Testing
- propofol, desflurane
- Where
- Australia
- Volunteers
- 182 people
- Sponsor
- University of Melbourne
Postoperative Delirium
Treatment of Postoperative Delirium With Continuous Theta Burst Stimulation
To determine whether continuous theta burst stimulation can cure postoperative delirium in senior patients.
- Trial name
- NCT05239897
- Testing
- Continuous theta burst stimulation (cTBS)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Delirium - Postoperative
Perioperative Antibiotic Exposure and Postoperative Delirium in Older Adults Undergoing Elective Non-cardiac Surgery: A Single-center Prospective Cohort Study
This study aimed to characterize the current patterns of perioperative prophylactic antibiotic use and to systematically evaluate the association between different antibiotic classes and the occurrence of POD, thereby providing…
- Trial name
- NCT07673510
- Testing
- Perioperative antibiotics exposure
- Where
- China
- Volunteers
- 4,711 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Delirium
Relevance of the Peripheral Cholinesterase-activity on Neurocognitive Dysfunctions in Surgical Patients
In this prospective, multicenter observational study the investigators capture the perioperative course of peripheral cholinesterase activity. The focus is the perioperative inflammation causing postoperative delirium.
- Trial name
- CESARO (NCT01964274)
- Where
- 9 sites in Germany
- Volunteers
- 815 people
- Sponsor
- Charite University, Berlin, Germany
Delirium in Old Age
Predicting Delirium by Attentional Dysfunction
Rationale: Delirium is a common complication that occurs in various medical conditions. Validated models predicting delirium in individual patients are scarce and existing models tend to focus on demographic characteristics and…
- Trial name
- RAPID (NCT03988179)
- Testing
- The Cholinesterase Inhibitor Prognosticator (ChIP) application for iPad
- Volunteers
- 172 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Emergence Agitation
Propofol in Emergence Agitation
The purpose of the study is to see if a small dose of propofol given intravenously (through a needle into a vein) at the end of anesthesia can make it less likely that children will be agitated as the come out of the anesthetic.
- Trial name
- NCT00535613
- Testing
- Propofol
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Wisconsin, Madison
Post-Intensive Care Syndrome
Collaborative Assessment of ICU Recovery Needs
The primary purpose of this study is to better understand the impact of the Society of Critical Care Medicine (SCCM) THRIVE Collaboratives on patients, their families and clinicians.
- Trial name
- CAIRN (NCT03513289)
- Testing
- Patient, Carer, and Clinician Interviews
- Where
- 2 sites in United States, Australia
- Volunteers
- 66 people
- Sponsor
- Vanderbilt University Medical Center
Cervical Spinal Stenosis, Thoracic Spinal Stenosis
The Effect of Oxytocin Nasal Spray on Preventing Postoperative Delirium in Elderly Patients Undergoing Orthopedic Surgery
Postoperative delirium is a delirium that occurs within 7 days after surgery or before hospital discharge. It has been shown that combined POD can increase the incidence of postoperative pulmonary infections, deep vein thrombosis…
- Conditions
- Cervical Spinal Stenosis, Thoracic Spinal Stenosis, Lumbar Spinal Stenosis, Rotator Cuff Injury
- Trial name
- NCT06945926
- Testing
- oxytocin nasal spray
- Where
- China
- Volunteers
- 227 people
- Sponsor
- Zhejiang University
Delirium Superimposed on Dementia
Study of the Aliviado DSD Caregiving Mastery Program
Delirium superimposed on dementia (DSD) is an acute and serious condition that is common in persons living with dementia (PLWD). Involvement of family caregivers may aid prevention, early detection, and management of DSD.
- Trial name
- NCT05630014
- Testing
- Aliviado DSD Caregiving Mastery Program
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health