Clinical trials: Delirium, completed
Delirium, Cerebral Infarction
the Incidence and the Association Between Motor Subtypes and Outcome of Delirium in Ischemic Stroke Patients
this study examines the incidence of newly developed delirium in patients who admit to university hospital stroke unit for cerebral infarction, and analyze the association between delirium motor subtypes and short-term outcome in…
- Trial name
- NCT03317106
- Where
- South Korea
- Volunteers
- 943 people
- Sponsor
- Chungnam National University Hospital
Delirium, Delirium, Dementia, Amnestic, Cognitive Disorders
Ramelteon in the Prevention of Post-operative Delirium
This trial focuses on a Phase II randomized masked clinical trial testing the effectiveness and safety of peri-operative administration of ramelteon, a melatonin agonist in the prevention of postoperative delirium.
- Conditions
- Delirium, Delirium, Dementia, Amnestic, Cognitive Disorders, Delayed Emergence From Anesthesia, Cognitive Disorders
- Trial name
- RECOVER (NCT02324153)
- Testing
- Ramelteon, Microcrystalline Cellulose, Riboflavin 100 mg
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Johns Hopkins University
Postoperative Pain, Postoperative Delirium
Multimodal Versus Opioid aNalgesia in carDiAc Surgery
To compare standard "Fentanyl - Tramadol - Paracetamol - Oxycodone" regimen to a multimodal painmanagement "pregabalin- minimal fentanyl-ketamine-lidocain-dexmedetomidine- paracetamol" to determine which therapy provides the most…
- Trial name
- MONDAY (NCT04987372)
- Testing
- Dexmedetomidine
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Alzheimers Disease, Postoperative Delirium
Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care
This study will examine the hypothesis that changes in the cognition (i.e. thinking and memory) after anesthesia and surgery are correlated with changes in markers of Alzheimers Disease in the fluid around the brain and spinal…
- Conditions
- Alzheimers Disease, Postoperative Delirium, Post Operative Cognitive Dysfunction
- Trial name
- MADCO-PC (NCT01993836)
- Testing
- Total intravenous anesthesia with propofol, General anesthesia with isoflurane
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Duke University
Postoperative Cognitive Dysfunction, Delirium, Postoperative
Evaluation of the Predictive Impact of Serum S100B and S100B Polymorphisms on Postoperative Cognitive Dysfunction and Delirium
Postoperative cognitive disorders, including postoperative cognitive dysfunction (POCD) and postoperative delirium (POD), are common complications following surgery and anesthesia, particularly in vulnerable patient populations.
- Trial name
- NCT07509372
- Testing
- Perioperative Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people
- Sponsor
- Ankara University
Post Operative Delirium
Dexmedetomidine Dosage for Postoperative Delirium and Cognitive Function in Elderly TKA Patients
This study aims to evaluate the efficacy of dexmedetomidine in reducing the incidence of postoperative delirium and cognitive dysfunction in elderly patients undergoing total knee arthroplasty (TKA).
- Trial name
- NCT06614881
- Testing
- Dexmedetomidine Injection [Precedex], Dexmedetomidine in 0.9 % NaCl 1,000 Mcg/250 mL (4 Mcg/mL) INTRAVEN INFUSION BOTTLE (ML), Normal saline
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Tanta University
Cognitive Disorders, Delirium
The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction
Ketamine is a commonly used anesthetic medication which is used for induction of anesthesia as well as as an analgesic. It has been shown to have anti-inflammatory properties which may decrease post-operative complications…
- Conditions
- Cognitive Disorders, Delirium, Acute Kidney Injury
- Trial name
- NCT02554253
- Testing
- Ketamine, Propofol
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Mayo Clinic
Lumbar Spine Disease
Deep Neuromuscular Block on Postoperative Delirium in Lumbar Surgery
The effect of deep neuromuscular blockade (NMB) during spine surgery reduced postoperative pain and bleeding in recent studies. Therefore by reducing these two factors, which were the contributing factors for postoperative…
- Trial name
- NCT05453929
- Testing
- Rocuronium for deep NMB, Rocuronium for moderate NMB
- Where
- South Korea
- Volunteers
- 230 people
- Sponsor
- Korea University Guro Hospital
Delirium in Old Age
Delirium Treatment With Acupuncture in Internal Medicine Departments
Delirium frequently occurs in hospitalized older people, and treatment options are limited. Acupuncture has been shown to reduce agitation in the setting of dementia.
- Trial name
- NCT03398928
- Testing
- Acupuncture
- Where
- Israel
- Volunteers
- 81 people
- Sponsor
- Bnai Zion Medical Center
Postoperative Delirium, Postoperative Cognitive Dysfunction
The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study
The objective of this study is to test the effects of caffeine on neurocognitive and clinical recovery after major surgery. Specifically, this trial tests the primary hypothesis that caffeine will reduce the incidence of…
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Mild Cognitive Impairment
- Trial name
- NCT05574400
- Testing
- Dextrose Water, Caffeine citrate
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Michigan
Colorectal Cancer (MSI-H), Postoperative Delirium (POD)
POD Risk for Colorectal Cancer Surgery
Postoperative delirium is a common complication after colorectal cancer surgery that hinders recovery. This observational study hypothesizes that a simple, practical risk tool can be developed by combining preoperative clinical…
- Trial name
- NCT07597330
- Where
- China
- Volunteers
- 590 people
- Sponsor
- LanZhou University
Delirium, Fall Injury
Care.Coach Avatars for Improvement of Outcomes in Hospitalized Elders, Including Mitigation of Falls and Delirium: a Multi-Site Clinical Study
Through NINR project 1R44NR017842-01 which preceded the present study, the investigators enhanced the care.coach avatar platform to incorporate a robust suite of evidence-based protocols based on the Hospital Elder Life Program…
- Trial name
- AvatarHELP (NCT03832192)
- Testing
- care.coach Avatar (HELP-Protocolized)
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Victor Wang
Delirium, Older Patients
Delirium in Geriatric Hospital Single-bed and Multibed Rooms
To investigate whether single-bed rooms can prevent and reduce incidence and duration of delirium compared to multi-bed rooms in elderly patients admitted to a geriatric department.
- Conditions
- Delirium, Older Patients, Admittance to Single-bed Rooms or Multi-bed Rooms
- Trial name
- NCT03199768
- Where
- Denmark
- Volunteers
- 1,014 people
- Sponsor
- Aarhus University Hospital
Delirium
pRophylactic halopEriDol Use for Delirium in iCu patiEnts With a High Risk for Delirium
The aim of this study is to determine the effects of a low dosage of prophylactic haloperidol in patients with a high risk to develop delirium, defined by an expected ICU length of stay of >1 day.
- Trial name
- REDUCE (NCT01785290)
- Testing
- Haloperidol 1 mg/q8h, Haloperidol 2 mg/q8h
- Where
- Netherlands
- Volunteers
- 1,800 people
- Sponsor
- Radboud University Medical Center
Weakness, Muscle, Delirium in Old Age
YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobility
Patients admitted to the hospital often develop functional impairments due to being in bed most of the day. Each day of bedrest leads to significant muscle loss.
- Conditions
- Weakness, Muscle, Delirium in Old Age, Muscle Atrophy or Weakness, Muscle Loss
- Trial name
- YOOMI (NCT05815017)
- Testing
- Yoomi Physical Therapy Software
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Surgery, Stress
The Effects of Healing Touch on Post Operative Pediatric Patients
The goal of this study is to assess the benefits of Healing Touch, an energy based therapy on post-operative discomfort and the rate of recovery in children.
- Conditions
- Surgery, Stress, Pain, Children
- Trial name
- NCT01738308
- Testing
- Healing Touch
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Delirium, Pain, Postoperative
Use of Pupillometry for Pain Assessment in ICU Patients With Delirium
Pain assessment in intensive care patients is a constant challenge. Approximately 50% to 80% of patients report pain at rest or during medical or nursing interventions (for example endotracheal suctioning, mobilization and…
- Trial name
- NCT05811208
- Testing
- automated pupillometry, questionnaire
- Where
- Czechia
- Volunteers
- 49 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Delirium
International Multicenter Study One Day Prevalence Observational Study for Delirium on ICU
An anonymous international multicenter - clinical survey, one-day observational study.
- Trial name
- IMPROVE-ICU (NCT01278524)
- Where
- Germany
- Volunteers
- 1,002 people
- Sponsor
- Claudia Spies
Delirium - Postoperative, BDNF
The Relationship Between Delirium and BDNF in Coronary Artery Bypass Graft Surgery
This study is aimed at finding a correlation between postoperative delirium occurrence, severity and duration after cardiac surgery and the level of brain-derived neurotrophic factor (BDNF) in plasma as a marker of brain injury…
- Conditions
- Delirium - Postoperative, BDNF, CABG
- Trial name
- NCT06967779
- Where
- Poland
- Volunteers
- 107 people
- Sponsor
- Pomeranian Medical University Szczecin
Delirium
Wearable Sensors for Delirium Detection at an Early Stage (WeSen_delirium)
Delirium is an acute brain-organic syndrome: its clinical manifestation and form are results of a highly complex pathophysiology. Delirium is a serious clinical problem in hospitalized adults.
- Trial name
- NCT05677646
- Where
- 2 sites in Switzerland
- Volunteers
- 47 people
- Sponsor
- University of Zurich