Clinical trials: Delirium - Postoperative, open to volunteers
Emergence Delirium, Anesthesia
The Effect of EEG and BIS-guided Anaesthesia on the Incidence of Emergent Delirium in Children
The aim of the study is to compare two modalities of measuring the depth of general anaesthesia on the incidence of emergent delirium in children.
- Trial name
- NCT07534215
- Testing
- EEG monitoring, BIS monitoring
- Where
- Czechia
- Volunteers
- 540 people
- Sponsor
- University Hospital Ostrava
Lumbar Disc Herniation, Emergence Agitation
Magnesium Sulfate for Prevention of Emergence Agitation in Lumbar Disc Surgery
In this retrospective study, the effect of intraoperative magnesium sulfate infusion on the incidence of postoperative emergence agitation was evaluated in adult patients who underwent elective lumbar microdiscectomy under…
- Conditions
- Lumbar Disc Herniation, Emergence Agitation, Magnesium Sulfate
- Trial name
- NCT07139847
- Testing
- Magnesium Sulfate Infusion, 0.9% Saline Infusion
- Volunteers
- 70 people
- Sponsor
- Ondokuz Mayıs University
Postoperative Delirium (POD), Gynecologic Cancers
Immunonutrition and Neuromonitoring for Postoperative Delirium in Gynecologic Oncology
Early postoperative delirium (POD) is a common and distressing neuropsychiatric complication frequently observed in elderly patients undergoing major surgical interventions, including radical and cytoreductive gynecologic…
- Conditions
- Postoperative Delirium (POD), Gynecologic Cancers, Malnutitrion
- Trial name
- NCT07877285
- Testing
- Preoperative Immunonutritional Scoring and Intraoperative Neuromonitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Agitation, Postoperative Agitation
Effect of Daily Screen Time on Postoperative Emergence Delirium in Children Aged 2-11 Years
This prospective observational study aims to evaluate the association between daily screen exposure duration and postoperative emergence delirium in children aged 2 to 11 years undergoing elective lower abdominal surgery.
- Trial name
- NCT07552896
- Testing
- Daily Screen Exposure Duration
- Where
- Turkey (Türkiye)
- Volunteers
- 288 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Frailty
Preoperative Frailty and Postoperative Neurocognitive Disorders in Geriatric Patients in Georgia
The number of elderly people in the global population is growing, presenting an increasing challenge. Technological advances in medicine have made it possible to perform complex surgeries on geriatric patients, improving the…
- Trial name
- FRAILCOG-GE (NCT06700291)
- Testing
- Surgery
- Where
- Georgia
- Volunteers
- 230 people
- Sponsor
- New Hospitals Georgia
Postoperative Delirium (POD), Prostate Cancer
Preoperative Breathing Exercise Training and Postoperative Delirium After Robotic Radical Prostatectomy
Postoperative delirium is an acute and fluctuating disturbance in attention, awareness, and thinking that may occur after major surgery.
- Trial name
- NCT07766603
- Testing
- Preoperative Deep Breathing Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- ALİ DEMİRTAŞ
Emergency Delirium, Postoperative Delirium (POD)
Comparison of IV Dexmedetomidine Versus Clonidine Versus no Alpha 2 Agonist on Emergency Delirium, PACU Length of Stay and Time to Hospital Discharge in Children Undergoing (Adeno)Tonsillectomy: a Prospective Observational Study
Emergence delirium (ED) is a frequent complication in children undergoing general anesthesia, particularly following ENT procedures such as adenotonsillectomy.
- Conditions
- Emergency Delirium, Postoperative Delirium (POD), Adenotonsillectomy, Tonsillectomy
- Trial name
- CLONIDEX (NCT07913308)
- Testing
- Intravenous dexmedetomidine, Intravenous clonidine, Standard Anesthetic Care Without Alpha-2 Agonist
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Postoperative Delirium
Prevention of Postoperative Delirium in Elderly Patients
Prevention of Postoperative Delirium in the care of Elderly Patients. A Monocentric, Prospective Intervention Study With the Question of Whether the Incidence, Length and Severity of Postoperative Delirium Can be Reduced by…
- Trial name
- PODproject (NCT06248684)
- Testing
- standardized prevention and therapy measures
- Volunteers
- 15,000 people
- Sponsor
- Technical University of Munich
Emergence Agitation, General Anesthesia
Low-dose Versus Standard-dose Remimazolam for Prevention of Emergence Agitation After Nasal Surgery
Emergence agitation (EA) is a common complication during recovery from sevoflurane anesthesia, particularly after nasal surgery.
- Conditions
- Emergence Agitation, General Anesthesia, Nasal Surgical Procedures
- Trial name
- NCT07740655
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 138 people
- Sponsor
- Jeju National University School of Medicine
Delirium - Postoperative, Postoperative Cognitive Dysfunction (POCD)
Value of the Time-Weighted Average (TWA) of Mean Arterial Pressure (MAP) and Cerebral Oximetry (rSO₂) as Predictors of Postoperative Tissue Perfusion Impairment in Patients Undergoing Cardiac Surgery
Neurological problems after heart surgery are common and include confusion, memory loss, and difficulty thinking clearly. These issues may appear hours or days after surgery and can negatively affect recovery.
- Conditions
- Delirium - Postoperative, Postoperative Cognitive Dysfunction (POCD), Postoperative Acute Kidney Injury, Postoperative Morbidity
- Trial name
- NCT07510711
- Testing
- Continuous intraoperative monitoring of MAP and rSO₂; observational study with no therapeutic intervention.
- Volunteers
- 120 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Delirium on Emergence
Sevoflurane/Dexmedetomidine vs. Isoflurane for Pediatric Emergence Delirium
The purpose of this study is to measure the incidences of pediatric emergence delirium between the group receiving Isoflurane and the group receiving Sevoflurane plus intravenous push dexmedetomidine.
- Trial name
- NCT06624592
- Testing
- Sevoflurane, Isoflurane
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Mayo Clinic
Cerebral Oxygen Saturation, Postoperative Delirium
Association Between Local Cerebral Oxygenation Monitoring and Postoperative Delirium in Carotid Endarterectomy
Postoperative delirium (POD) is a common perioperative complication, which can lead to adverse outcomes. Patients undergoing carotid endarterectomy (CEA) were elderly, complicated with vascular risk factors, cognitive…
- Conditions
- Cerebral Oxygen Saturation, Postoperative Delirium, Carotid Endarterectomy
- Trial name
- NCT05198635
- Testing
- local cerebral oxygen saturation
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Beijing Tiantan Hospital
Postoperative Delirium (POD), Cerebral Small Vessel Diseases
Prospective Randomized Controlled Trial of VR Cognitive Training in Reducing Postoperative Delirium in Elderly Patients With Cerebral Small Vessel Disease Undergoing Non-Cardiac Surgery
This clinical study investigates whether virtual reality (VR)-based cognitive training can help prevent postoperative delirium (POD) in elderly non-cardiac patients with pre-existing cerebral small vessel disease (CSVD).
- Trial name
- NCT06999668
- Testing
- Virtual reality cognitive function training, Virtual scene intervention
- Where
- 2 sites in China
- Volunteers
- 416 people
- Sponsor
- Peking University Third Hospital
Postoperative Delirium
Postoperative Delirium in Patients Undergoing Cardiac Surgery
Establish a follow-up database for postoperative delirium in cardiac surgery patients, adopt a bidirectional cohort design to simultaneously analyze the associations between "preoperative exposure factors and postoperative…
- Trial name
- NCT07239648
- Testing
- Serum metabolic profile
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Xijing Hospital
Dexmedetomidine, Delirium
Effect of Dexmedetomidine on Postoperative Delirium After Awake Craniotomies
Postoperative delirium (POD) is a common complication, and the incidence of POD ranges from 10% to 60%. Previous studies suggested that frontal approach and tumor located at the temporal lobe were independent risk factors for POD…
- Conditions
- Dexmedetomidine, Delirium, Awake Craniotomy
- Trial name
- NCT05195034
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Beijing Tiantan Hospital
Postoperative Delirium
The Role of Emotional and Orientation Support in Prevention of Postoperative Delirium Among Elderly Surgical Patients
Postoperative delirium is common and associated with significant adverse outcomes. Its etiology is unknown, and little is known about associated risk factors.
- Trial name
- NCT05140993
- Testing
- extended emotional and orientation support
- Where
- Israel
- Volunteers
- 2,000 people
- Sponsor
- Barak Cohen, MD
Postoperative Agitation, Emergence Delirium, Anesthesia
Impact of Neuromonitoring on Postoperative Agitation in Pediatric General Anesthesia
Postoperative agitation is frequently observed in the pediatric patient group following general anesthesia. The exact cause of this agitation has not been clearly determined; however, it may be associated with various factors…
- Trial name
- NCT07243990
- Testing
- dsa intervention group, Traditional Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sakarya University
CGA
Preoperative Comprehensive Geriatric Assessment (CGA) and Postoperative Delirium
The purpose of this research is to find out the best way to reduce delirium in frail, older patients undergoing planned surgery. Delirium is a state of confusion and difficulty concentrating that is temporary.
- Trial name
- NCT07059585
- Testing
- CGA, control
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Miami
Emergence Delirium, Anesthesia
Study on the Correlation Between Plasma Orexin Levels During the Recovery Period and Emergence Delirium in Elderly Patients
To explore the relationship between plasma orexin levels during the recovery period of elderly patients undergoing general anesthesia and the occurrence of emergence delirium, and to evaluate its sensitivity and specificity as an…
- Trial name
- NCT07726875
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Ruijin Hospital
Postoperative Cognitive Complications, Delirium
Prospective Observational Multimodal Neuromonitoring During High-Risk Adult Surgery
This is a prospective observational cohort study of adult patients undergoing high-risk surgery at UT Southwestern Medical Center.
- Conditions
- Postoperative Cognitive Complications, Delirium, Perioperative/Postoperative Complications, Brain Injuries
- Trial name
- NCT07577726
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center