Clinical trials: Delirium in Intensive Care Unit
Delirium, Intensive Care Unit
Effectiveness of a Virtual Reality-Based Sensory Stimulation Intervention in Preventing Delirium in Intensive Care Units
The goal of this clinical trial is to evaluate the effectiveness of a VR-based sensory stimulation system in preventing ICU delirium in patients.
- Conditions
- Delirium, Intensive Care Unit, Randomised Controlled Trial
- Trial name
- NCT06153472
- Testing
- VR-based intervention
- Volunteers
- 324 people
- Sponsor
- Chinese University of Hong Kong
Delirium, Cognitive Impairment
Family Automated Voice Reorientation Study
This randomized clinical trial tests a cognitive reorientation intervention to prevent delirium in the intensive care unit using scripted audio messages, recorded by the patient's family and played at hourly intervals during…
- Conditions
- Delirium, Cognitive Impairment, Health, Subjective, Sleep
- Trial name
- FAVoR (NCT03128671)
- Testing
- FAVoR Intervention
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- University of Miami
Sleep Disorders, Delirium
Evaluation of Risk Factors of Sleep Quality in Intensive Care Unit
The aim of this study was to investigate the relationship between sleep disturbances and delirium in surgical ICU patients. The study set up to test the hypothesis that the occurrence of delirium is associated to the alteration…
- Trial name
- NCT00507481
- Where
- 2 sites in Italy
- Sponsor
- University of Turin, Italy
Delirium, Cognitive Impairment
Stanford ICU Delirium PIPRA Study
The purpose of this study is to determine the accuracy of the Pre-Interventional Preventive Risk Assessment (PIPRA) tool in predicting clinical cases of Intensive Care Units (ICU)-delirium, in a population at high risk of…
- Conditions
- Delirium, Cognitive Impairment, Delirium, Postoperative
- Trial name
- SIDPVS (NCT06519890)
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Stanford University
Delirium, Critical Illness
Haloperidol for Delirium in Adult Critically Ill Patients
The EuRIDICE trial will study whether haloperidol as a first line treatment for ICU delirium reduces delirium duration (and severity).
- Conditions
- Delirium, Critical Illness, Intensive Care Psychosis, Cognitive Impairment
- Trial name
- EuRIDICE (NCT03628391)
- Testing
- Haloperidol
- Where
- 8 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- Erasmus Medical Center
Delirium
Subsyndromal Delirium in Intensive Care Unit
Subsyndromal delirium (SSD) is a condition characterized by a less severe cognitive impairment in comparison to delirium. To date there is no published consensus on SSD definitions and has been commonly reported as an…
- Trial name
- SubSynD (NCT03813459)
- Where
- Portugal
- Volunteers
- 400 people
- Sponsor
- Centro Hospitalar Lisboa Ocidental
Delirium, Mechanical Ventilation
Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Unit
Delirium is one of main adverse events in ventilated patients who receive long-term usage of mono-sedative. Sequential sedation may reduce these adverse effects.
- Conditions
- Delirium, Mechanical Ventilation, Sedation
- Trial name
- NCT03194360
- Where
- China
- Volunteers
- 141 people
- Sponsor
- West China Hospital
Abdominal Surgery
The Effect of Eye Mask and Music on Sleep Quality and Delirium in Patients Monitored in Intensive Care Unit
After abdominal surgery, most patients experience problems such as respiratory complications, surgical wound infection, cardiac problems, renal failure, delirium, and insomnia, along with surgical trauma and underlying…
- Trial name
- NCT06268158
- Testing
- Eye patch
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Deep Sedation, Ventilators, Mechanical
Pain, Agitation and Delirium (PAD) Protocol in the Duke CICU
This study aims to examine the use of protocol directed sedation using the Duke PAD protocol with the current sedation medications of propofol or dexmedetomidine compared to the PAD protocol with midazolam, per cardiac intensive…
- Conditions
- Deep Sedation, Ventilators, Mechanical, Critical Illness
- Trial name
- NCT02903407
- Testing
- Midazolam, Propofol, Dexmedetomidine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duke University
Delirium
The ICU DElirium in Clinical PracTice Implementation Evaluation Study Screening and Treatment
Objective: Delirium is an important and frequently occurring complication in intensive care patients. However, screening and treatment of delirium is not in accordance with current national and international guidelines.
- Trial name
- iDECePTIvE (NCT01952899)
- Where
- Netherlands
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Mechanical Ventilation, Sedation
Implementation of an Analgesia-sedation Algorithm in the Pediatric ICU to Reduce Benzodiazepine Use
The purpose of the study is to develop and implement an evidence-based analgesia-sedation algorithm in the pediatric intensive care unit (PICU) using quality improvement and implementation science methodology.
- Trial name
- NCT04263662
- Testing
- Analgesia-Sedation algorithm
- Where
- United States
- Volunteers
- 680 people
- Sponsor
- Boston Children's Hospital
Traumatic Brain Injury, Delirium
Comparison of Haloperidol and Dexmedetomidine for Delirium and Agitation in ICU Patients With Traumatic Brain Injury
Traumatic brain injury is a serious and common medical condition that often requires admission to the intensive care unit and the use of mechanical ventilation.
- Conditions
- Traumatic Brain Injury, Delirium, Agitation
- Trial name
- NCT06993194
- Testing
- Haloperidol, Dexmedetomidine
- Volunteers
- 40 people
- Sponsor
- Benha University
Delirium, Confusion
Intelligent Intensive Care Unit
Delirium, as a common complication of hospitalization, poses significant health problems in hospitalized patients. Though about a third of delirium cases can benefit from intervention, detecting and predicting delirium is still…
- Trial name
- ICU_Delirium (NCT02465307)
- Testing
- Confusion Assessment Method, Accelerometer, Commercially available camera
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Florida
Septic Shock, Delirium
Septic Shock and Delirium Because of rSO2 Abnormalities in Intensive Care Unit Patients (The SAD BRAIN Study)
Delirium in the ICU is a prevalent problem occurring in up to 80% of ICU patients. A potential cause of delirium in ICU patients could be cerebral hypoxia. Septic shock is associated with high rates of delirium.
- Conditions
- Septic Shock, Delirium, Renal Failure
- Trial name
- NCT01836302
- Testing
- Observation
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Manitoba
Delirium
Delirium Assessment in the Pediatric Intensive Care Unit
The aim of this study was to show the efficacy of non-pharmacological interventions on preventing pediatric delirium in pediatric intensive care unit
- Trial name
- NCT04041947
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Cukurova University
Delirium, Agitation
A Comparison of Dexmedetomidine and Haloperidol in Patients With Intensive Care Unit (ICU)-Associated Agitation and Delirium
The purpose of the study is to determine whether dexmedetomidine is a more effective medication than haloperidol in the treatment of agitation and delirium in patients receiving mechanical ventilation in an intensive care unit.
- Conditions
- Delirium, Agitation, Ventilator Weaning, Respiration, Artificial
- Trial name
- Dex (NCT00505804)
- Testing
- dexmedetomidine, haloperidol
- Volunteers
- 20 people
- Sponsor
- Austin Health
Delirium
Incidence and Prognostic Value of Delirium in Patients With Acute Coronary Syndromes
The Purpose of this study is to evaluate the incidence of delirium in patients with acute coronary syndromes admitted to a Intensive Care Unit Patients.
- Trial name
- NCT02356523
- Testing
- Confusion Assessment Method
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Ospedale San Donato
Intensive Care Patients, Relatives
Family Involvement in ICU
The aim of this prospective cohort study was to investigate the effect of the time spent with relatives of patients treated in a tertiary intensive care unit on patient outcomes.
- Conditions
- Intensive Care Patients, Relatives, Delirium in the Intensive Care Unit, Sedatives
- Trial name
- NCT06770751
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Istanbul University - Cerrahpasa
Implementation Science, Delirium
Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts
There is a fundamental gap between the discovery of proven-effective intensive care unit (ICU) sedation, mechanical ventilation, mobility, and symptom management strategies and approaches that can equip ICU providers with the…
- Conditions
- Implementation Science, Delirium, Intensive Care Unit Acquired Weakness, Pain
- Trial name
- DISCOVER-ICU (NCT04249141)
- Testing
- Survey and concept mapping
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University
Delirium, Critical Illness
Pain Assessment in the Intensive Care Unit
Pain assessment using self-report scales (Visual Analogue Scale, Numerical Rating Scale), is recommended in the general population, however it is not always possible in patients with altered neurological status such as sedated…
- Trial name
- NCT01628185
- Testing
- Repositioning
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago