Clinical trials: Delivery; Trauma
Childbirth-related PTSD, PTSD
International Survey of Childbirth-Related Trauma - Swedish Part
The goal of this cross-sectional observational study is to analyze childbirth-related PTSD, traumatic birth experiences and stress symptoms postpartum.
- Conditions
- Childbirth-related PTSD, PTSD, Postnatal Depression, Fear of Childbirth
- Trial name
- SwIntersect (NCT06207916)
- Where
- Sweden
- Volunteers
- 619 people
- Sponsor
- Region Östergötland
Concussion, Brain, Concussion, Mild
Mobile Subthreshold Exercise Program for Concussion--R01
Approximately 1.9 million youth sustain a concussion each year, and up to 30% experience persistent post-concussive symptoms (PPCS) such as headache, dizziness, and difficulty focusing that continue for weeks or months.
- Conditions
- Concussion, Brain, Concussion, Mild, Brain Injuries, Traumatic, Persistent Post Traumatic Headache
- Trial name
- MSTEP-R01 (NCT04688255)
- Testing
- MSTEP, Stretching
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Seattle Children's Hospital
Psychological Distress, Depression
Peer Intervention to Improve Access Among Rural Women Veterans With Psychological Distress and Unmet Social Needs
This research project will refine and evaluate delivery of a peer-delivered evidence-based intervention to improve perceived access and actual engagement with mental health treatment and social resource service use among rural…
- Conditions
- Psychological Distress, Depression, PTSD, Anxiety
- Trial name
- EMBER (NCT05477706)
- Testing
- Personalized Support for Progress (PSP), Tailored Referral (TR)
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Syracuse VA Medical Center
Wound Complication
Cesarean Skin Incision Trial
The purpose of this study is to determine if there is a difference between Pfannenstiel and midline vertical skin incision at time of cesarean section in preventing wound complications in the morbidly obese patient.
- Trial name
- C-SIT (NCT01897376)
- Testing
- Pfannenstiel incision, vertical skin incision
- Where
- 2 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Pain
The Analgesic Efficacy of Wound Infiltration With Tramadol
This double-blind, randomized trial examined whether tramadol wound infiltration decreased postoperative pain following cesarean delivery under general anesthesia or reduced the need for analgesics in the immediate postoperative…
- Trial name
- NCT02518438
- Testing
- Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yeditepe University Hospital
Radiotherapy Side Effect
Evaluation of Music on the Level of Anxiety Felt During External Radiotherapy Sessions
This is a prospective study with a historical comparator. Each of the prospective study endpoints will be compared to data collected retrospectively in patients treated with radiation therapy prior to the implementation of the…
- Trial name
- MUSIC-RT (NCT05289505)
- Testing
- MUSIC-CARE
- Where
- France
- Volunteers
- 83 people
- Sponsor
- Center Eugene Marquis
Birth Asphyxia
Asphyxia Associated Metabolite Biomarker Investigation 2
Follow-up of participants of AAMBI1 study at age of at least 2 years. AAMBI1(ClinicalTrials.gov ID: NCT03354208): Verification of biomarkers in a human population for their ability to diagnose the severity of neonatal asphyxia.
- Trial name
- AAMBI2 (NCT04714502)
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- InfanDx AG
Prematurity, Oxidative Injury
Comparison of Different Oxygen Delivery Strategies During Resuscitation of Babies
Preterm infants are born with immature lungs and often require help with breathing shortly after birth. This currently involves administering 100% oxygen.
- Conditions
- Prematurity, Oxidative Injury, Respiratory Distress
- Trial name
- NCT00356902
- Testing
- titration of oxygen during resuscitation
- Where
- Canada
- Volunteers
- 215 people
- Sponsor
- University of Calgary
Infant,Premature, Bronchopulmonary Dysplasia
L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects up to 35% of very low birth weight infants (VLBW < 1500 g).
- Conditions
- Infant,Premature, Bronchopulmonary Dysplasia, Pulmonary Hypertension
- Trial name
- NCT03542812
- Testing
- L-Citrulline
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Utah
Birth Outcome, Adverse
Knowledge, Attitudes, and Practices of Operative Vaginal Birth Among Obstetric Providers in Egypt
The goal of this observational study is to evaluate the knowledge, attitudes, and practices of operative vaginal birth among obstetric providers in Egypt.
- Trial name
- NCT06502119
- Testing
- Designed Questionnaire
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Bronchopulmonary Dysplasia
Follow-Up Study of Safety and Efficacy of Pneumostem® in Premature Infants With Bronchopulmonary Dysplasia
This is a long term follow-up study of the open label, single-center, phase I clinical trial to evaluate the safety of Pneumostem® in premature infants with BPD.
- Trial name
- NCT01632475
- Testing
- Pneumostem®
- Where
- 2 sites in South Korea
- Volunteers
- 9 people
- Sponsor
- Samsung Medical Center
Sphincter (Anal); Perineal Rupture, Obstetric
Development and Validation of a Logistic Regression Algorithm to Predict the Risk of Obstetric Anal Sphincter Injury.
An obstetric anal sphincter injury (OASI) occurs during the final stage of a vaginal delivery. This tissue laceration, even if adequately sutured, poses a substantial threat to bowel continence in women.1,2 In a recent…
- Trial name
- NCT05218837
- Testing
- Vaginal birth
- Where
- Sweden
- Volunteers
- 800,000 people
- Sponsor
- Maria Gyhagen
Pelvic Floor Dysfunction, Perineal Laceration
Perineal Protection Device for Reducing Perineal Trauma During Vaginal Delivery in First-time Mothers: a Multicenter Randomized Controlled Trial
The goal of this clinical trial is to determine whether using a soft perineal protection device (BabySlide®) in addition to standard manual perineal support during vaginal delivery can reduce the risk of perineal trauma in…
- Conditions
- Pelvic Floor Dysfunction, Perineal Laceration, Wound Dehiscence, Anal Incontinence
- Trial name
- PeriPROTECT (NCT07862660)
- Testing
- Perineal protection device, BabySlide, Standard manual perineal support
- Where
- Sweden
- Volunteers
- 4,226 people
- Sponsor
- Region Skane
Prolonged Second Stage of Labor, Other Specified Trauma to Perineum and Vulva During Delivery
The Effect of Straining Techniques on Women and Newborn
Purpose: To examine the effects of straining techniques on the duration of labor, perineal trauma status and newborn apgar score. Method: This study is a randomized controlled trial.
- Conditions
- Prolonged Second Stage of Labor, Other Specified Trauma to Perineum and Vulva During Delivery, Newborn; Vitality
- Trial name
- NCT05578794
- Testing
- Straining types
- Where
- Turkey (Türkiye)
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Premature Birth, Brain Injury
Melatonin As A Novel Neuroprotectant In Preterm Infants- Dosage Study
Preterm babies are at risk of brain injury. Melatonin, a naturally occurring hormone, may reduce this risk. The unborn baby receives melatonin from the mother but following premature delivery there maybe a period of prolonged…
- Trial name
- MIND (NCT00649961)
- Testing
- Melatonin injection
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- Imperial College London
Infection of Cesarian Section Wound Following Delivery
Antibiotic Prophylaxis for Elective Cesarean Section
A randomized controlled study comparing the effect of administration of 1 gm ceftriaxone in elective cesarean section 30-60 min before skin incision versus after cord clamping.
- Trial name
- TOAPFECSACT (NCT02177994)
- Testing
- ceftriaxone 1gm for intravenous infusion
- Where
- Egypt
- Volunteers
- 328 people
- Sponsor
- Ain Shams Maternity Hospital
Contrast-induced Acute Kidney Injury (CI-AKI)
Hemodynamic Effects Of Impella On Renal Circulation And Risk Of CA-AKI Among Patients Undergoing Protected PCI
Patients undergoing Percutaneous Coronary Intervention (PCI) are exposed to the risk of suffering from a damage to the kidneys which goes under the name of Contrast-Associated Acute Kidney Injury (CA-AKI), which is more common if…
- Trial name
- NCT04928118
- Testing
- Evaluate the blood flow and pressure into kidneys
- Sponsor
- Virginia Commonwealth University
Facial Neoplasms, Head and Neck Neoplasms
Clinical Trial of New Elastomer for Maxillofacial Prosthetics
The purpose of this study is to evaluate a new rubber material used to make prosthetic replacements of the face lost to cancer, trauma, or birth defects.
- Conditions
- Facial Neoplasms, Head and Neck Neoplasms, Head Injuries, Penetrating, Birth Injuries
- Trial name
- NCT00123097
- Testing
- Chlorinated polyethylene elastomer
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Louisville
Early-Onset Sepses, Neonatal, Periventricular Haemorrhage Neonatal
Zinc Supplementation on Very Low Birth Weight Infant
Premature birth is a major cause of neonatal death in addition to neonatal asphyxia and infections. Early in life, premature babies must get aggressive nutrition so that there is no extrauterine growth restriction (EUGR) in the…
- Conditions
- Early-Onset Sepses, Neonatal, Periventricular Haemorrhage Neonatal, Bronchopulmonary Dysplasia, Retinopathy of Prematurity
- Trial name
- NCT04050488
- Testing
- Zinc Sulfate
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Perineal Tear, Delivery; Trauma
The Patient Positioning for Perineal Protection Study
It is common practice for practitioners to instruct patients to forcibly flex the hips at the time of delivery of the fetal vertex.
- Conditions
- Perineal Tear, Delivery; Trauma, Perineal Laceration
- Trial name
- 4P (NCT04616170)
- Testing
- Hip extension, Usual Care
- Where
- United States
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital