Clinical trials: Delivery
Labor Anxiety, Labor Delivery
Postpartum Effects of Mirror Therapy During Labor
Today, childbirth is considered one of the most physically and psychologically intense experiences in a woman's life. Labor is a critical period during which fear, anxiety, and stress related to childbirth may increase…
- Conditions
- Labor Anxiety, Labor Delivery, Labor, Labor Pain and to Reduce Pain
- Trial name
- NCT07792629
- Testing
- Mirror Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- NURTEN ÖZÇALKAP
Vaginal Delivery, Pelvic Organ Prolapse
EASE: The Materna Prep Pivotal Study
This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery.
- Trial name
- NCT03973281
- Testing
- Materna Prep Device, Standard of Care (SOC)
- Where
- 22 sites in United States
- Volunteers
- 420 people
- Sponsor
- Materna Medical
Cesarean Delivery, Postpartum Comfort
Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies
Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks.
- Conditions
- Cesarean Delivery, Postpartum Comfort, Postpartum Pain, Post-operative Pain
- Trial name
- PACESS (NCT07102641)
- Testing
- Acetaminophen, NSAID (Ketorolac/Ibuprofen)
- Where
- United States
- Volunteers
- 825 people
- Sponsor
- Thomas Jefferson University
Psychological Resilience Among Midwives Working in Delivery Rooms
Mandala Coloring and Resilience in Midwives
Midwives working in delivery rooms are exposed to occupational and psychological stressors associated with high workloads, shift work, time pressure, obstetric emergencies, and traumatic perinatal events.
- Trial name
- MCR-Midwives (NCT07788508)
- Testing
- Mandala Coloring
- Where
- 8 sites in Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
HIV, HIV Antiretroviral Therapy (ART) Adherence
Pilot Study to Evaluate the Decentralization of Patient Care Among People With HIV in Out-of-hospital Settings
The goal of this 24-week, open-label, randomized pilot study is to assess the feasibility and impact of decentralized HIV care in a community setting (BCN Checkpoint), focusing on patient satisfaction and experience and carbon…
- Conditions
- HIV, HIV Antiretroviral Therapy (ART) Adherence, Health Care Delivery
- Trial name
- OOH (NCT07792070)
- Testing
- Implemention of the decentralization of patient care into communitary facilities such as BCN Checkpoint/BCN Prep·Point.
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Bacterial Vaginosis, Vaginal Dysbiosis
AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm Birth
Preterm birth is a major cause of mortality and long-term disability. Bacterial vaginosis (BV) is a frequent form of dysbiosis that is often asymptomatic and increases the risk of preterm birth.
- Conditions
- Bacterial Vaginosis, Vaginal Dysbiosis, Premature Delivery
- Trial name
- AUTOP 2 (NCT06349122)
- Testing
- Vaginal flora abnormalities screening and quantification using molecular biology technique, Azithromycin, Ceftriaxone
- Volunteers
- 1,794 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Threatened Preterm Labor, Preterm Delivery
Evaluation of a New Predictive Test of Preterm Birth in Case of Threatened Preterm Labor
Threatened preterm labor (TPL) is defined by cervical changes and regular and painful uterine contractions occurring between 24 and 36 + 6 weeks of gestation that may or may not lead to premature labor and delivery.
- Trial name
- PREMAQUICK (NCT04374916)
- Testing
- Premaquick®, PARTOSURE®
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Epidural Analgesia, Epidural Analgesia for Labour and Delivery
EpiFaith Resident Learning Curve Trial
This study aims to evaluate the impact of the EpiFaith® syringe on the learning curve of anesthesia residents for the labor epidural technique.
- Conditions
- Epidural Analgesia, Epidural Analgesia for Labour and Delivery, Learning Curve
- Trial name
- NCT07395622
- Testing
- EpiFaith epidural syringe, Control (glass) syringe
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pregnancy, Labor Delivery
The Effect of Mental Toughness Interventions During Birth on the Pelvic Floor in the Postpartum Period
This randomized controlled study aimed to determine the effect of mental toughness interventions initiated during the third trimester of pregnancy and applied during childbirth on pelvic floor-related distress in the postpartum…
- Conditions
- Pregnancy, Labor Delivery, Breath Exercise, Relaxation
- Trial name
- NCT07771647
- Testing
- Mental Toughness
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Vitiligo Vulgaris, Microneedling-Assisted Delivery
Comparative Study of Topical Pentoxifylline Versus Topical 5-Fluorouracil Combined With Microneedling and NB-UVB for Stable Vitiligo
This randomized, single-blinded clinical trial evaluates the efficacy and safety of topical pentoxifylline compared with topical 5-fluorouracil, both combined with microneedling and narrow-band ultraviolet B (NB-UVB)…
- Conditions
- Vitiligo Vulgaris, Microneedling-Assisted Delivery, Phototherapy
- Trial name
- PTX-5FU-VIT (NCT07775105)
- Testing
- Microneedling + topical treatment (PTX 20 mg/ml) followed by NB phototherapy, Microneedling + topical treatment (5-FU 5%) followed by NB phototherapy, Microneedling alone followed by NB phototherapy
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Tanta University
Premature Birth, Premature Infant
Growing Little PEAPODS Study
The goal of this clinical trial is to learn more about how the food and nutrition babies receive while in the Neonatal Intensive Care Unit (NICU) influences their ability to gain weight and fat-free mass, and their future growth…
- Conditions
- Premature Birth, Premature Infant, Premature, Intrauterine Growth Restriction
- Trial name
- NCT06226051
- Testing
- PEAPOD Infant Body Composition measuring device
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Wisconsin, Madison
Eldery People, Cognitive Decline
Optimizing CNS DHA Delivery in Elderly Adults at Risk for Dementia
The purpose of this placebo-controlled trial is to compare the effects of 24-weeks supplementation with LPC-DHA and TAG-DHA on cerebrospinal fluid and blood DHA levels, as well as biomarkers of central neurodegenerative and…
- Conditions
- Eldery People, Cognitive Decline, Memory Decline, DHA CNS Delivery
- Trial name
- NCT06933095
- Testing
- LPC-EPA+DHA capsules containing omega-3 fatty acids EPA and DHA esterified to lysophosphatidylcholine (LPC-EPA+DHA)(Trade name: Lysoveta)
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- University of Cincinnati
Epidural Anesthesia in Labor and Delivery
The Effects of Epidural Analgesia on Maternal-Infant Bonding and Birth-Related Trauma
This prospective, single-center study aims to evaluate the effects of epidural analgesia on maternal-infant bonding and perceived birth-related trauma in women undergoing vaginal delivery.
- Trial name
- NCT07077785
- Testing
- Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Adiyaman University Research Hospital
Maternal Anxiety, Cesarean Delivery
Restrained vs Gripping String Techniques in Patients Undergoing Cesarean Delivery
This randomized controlled trial will compare two upper-extremity restraint techniques in patients undergoing elective cesarean delivery under neuraxial anesthesia.
- Trial name
- NCT07772219
- Testing
- Standard Forearm Restraint, Wrist-Level Gripping Restraint
- Where
- United States
- Volunteers
- 272 people
- Sponsor
- Ohio State University
Third Stage of Delivery
Maternal Outcomes Following Manual Lysis of the Placenta.
Comparison of maternal outcomes following manual lysis of placenta 15 vs 30 minutes after delivery. A primary outcome of the drop in hemoglobin will be compared between the two groups.
- Trial name
- NCT03626844
- Testing
- Manual Lysis of Placenta after 15 minutes (Intervention), Manual Lysis of Placenta after 30 minutes (Control)
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Vaginal Delivery
Practice of Assisted Vaginal Birth in Egypt
In Egypt, the proportion of CSs has been steadily increasing in recent years and has reached an alarming level. According to data from the Royal College of Obstetricians and Gynaecologists (RCOG), approximately 6% of caesarean…
- Trial name
- NCT07308977
- Testing
- Survey using a questionnaire.
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Maternal Health, Pregnancy
Understanding the Role of Doulas in Supporting People With PMADs
Detailed Description The doula-led intervention developed during the first phase of this project will be pilot tested for feasibility.
- Conditions
- Maternal Health, Pregnancy, Delivery, Obstetric, Self Efficacy
- Trial name
- NCT05763537
- Testing
- Standard Doula Care Plus PMAD Intervention, Standard Doula Care
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Montana
Small for Gestational Age at Delivery, Gestational Weight Gain
BEP Targeting Strategies in Ethiopia
The goal of this randomized effectiveness study is to evaluate the different targeting strategies for the delivery of balanced energy and protein (BEP) supplements among pregnant women in Addis Ababa, Ethiopia.
- Conditions
- Small for Gestational Age at Delivery, Gestational Weight Gain, Stillbirth, Preterm Birth
- Trial name
- BEP (NCT06125860)
- Testing
- Targeted BEP based on baseline nutritional status, Targeted BEP based on baseline nutritional status and monthly GWG monitoring, Universal BEP
- Where
- Ethiopia
- Volunteers
- 7,851 people
- Sponsor
- Harvard School of Public Health (HSPH)
Family Engagement, Patient and Family Engagement
The Family-ICU Trial
Family inclusion in adult intensive care unit (ICU) rounds is recommended by critical care professional societies, yet widespread uptake of this practice is limited.
- Conditions
- Family Engagement, Patient and Family Engagement, Health Care Delivery, Family-centered Care
- Trial name
- Family-ICU (NCT06586541)
- Testing
- Participation in attending team rounds
- Where
- 2 sites in Canada
- Volunteers
- 194 people
- Sponsor
- Lady Davis Institute
Perineal Injury, Perineal Laceration, Tear, or Rupture During Delivery
Targeted Deep Pelvic Floor Muscle Physiotherapy Versus Antenatal Perineal Massage in Nulliparous Women
This prospective randomized clinical trial evaluates whether targeted deep pelvic floor muscle physiotherapy is more effective than standard antenatal perineal massage in reducing perineal trauma among nulliparous women.
- Trial name
- NCT07764068
- Testing
- Targeted Deep Pelvic Floor Muscle Physiotherapy, Standard Antenatal Perineal Massage
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center