Clinical trials: Delivery
Breast Cancer Female
External Vacuum Expansion: Evaluation in Breast Reconstructive Surgery Evaluation in Breast Reconstructive Surgery
This multicentre randomized controlled trial aims to evaluate a new breast reconstruction technique- autologous fat transfer (AFT).
- Trial name
- EVE (NCT05003635)
- Testing
- EVEBRA device
- Where
- 3 sites in Netherlands
- Volunteers
- 90 people
- Sponsor
- Maastricht University Medical Center
Plasma Cell Myeloma Refractory
A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma
The primary purpose of this study is to assess the efficacy (overall response rate) of subcutaneous (SC) via on body delivery system (SC-OBDS) isatuximab in combination with weekly carfilzomib and dexamethasone (Kd) in adult…
- Trial name
- SubQSA (NCT06356571)
- Testing
- Isatuximab SC-OBDS, Montelukast, Dexamethasone
- Where
- 34 sites in United States
- Volunteers
- 64 people
- Sponsor
- Sanofi
Intrathecal Pump Refill
Intrathecal Pump Refills at Home or at the Hospital
The IMPROVE study is a randomized, controlled, cross-over trial designed to compare intrathecal pump refills performed at home with those carried out in the hospital.
- Trial name
- IMPROVE (NCT07727798)
- Testing
- Refill at the hospital, Refill at home
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- Moens Maarten
Premature Birth, Respiratory Distress Syndrome, Newborn
Non-invasive Neurally Adjusted Ventilator Assist or Continuous Positive Airway Pressure in Preterm Infants
Strategies to prevent lung injury, facilitate lung development, and to support the preterm infant's capacity to breathe are decisive.
- Trial name
- NCT04333563
- Testing
- CPAP, NIV NAVA
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- St. Olavs Hospital
Myocardial Infarction (MI), Radiation Toxicity
A MAajor RAdiation-based PCI Study in STEMI and NSTEMI
In France and Italy, approximately 240,000 percutaneous coronary angioplasties (PCI) are performed annually, with an increasing number of complex procedures, including those involving the left coronary common trunk, a…
- Conditions
- Myocardial Infarction (MI), Radiation Toxicity, Coronary Stenosis, Coronary Thrombosis
- Trial name
- MARAA (NCT06565793)
- Testing
- Non Complex PCI, Complex PCI
- Where
- France
- Volunteers
- 15,630 people
- Sponsor
- Centre Cardiologique du Nord
Infertility
Subcutaneous Progesterone in Frozen- Thawed Single Euploid Blastocyst Transfer.
This is a multicenter, randomized, double-blind, double-dummy, active-controlled, non-inferiority clinical study in women aged 35 to 42 years.
- Trial name
- PROGRESS (NCT04549116)
- Testing
- Progesterone-IBSA Injectable Solution, Progesterone Vaginal Gel with Applicator
- Where
- 24 sites in United States
- Volunteers
- 688 people
- Sponsor
- IBSA Institut Biochimique SA
Labour Analgesia and Neonate Activity
Labour Analgesia and Movement in Babies
This study aims to measure movements in babies after they are born using an actigraph, a wristwatch-sized device worn on the ankle, which works similarly to the device used by runners to count the number of steps they have taken.
- Trial name
- LAMB (NCT01280084)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chagas Disease, Lactation
Study of Benznidazole Transfer Into Breastmilk in Lactating Women With Chagas Disease
The investigators propose to study the transfer of benznidazole into breastmilk from the blood of lactating women who receive the drug for the treatment of Chagas disease.
- Trial name
- LACTBENZ (NCT01547533)
- Where
- Argentina
- Volunteers
- 10 people
- Sponsor
- Hospital de Niños R. Gutierrez de Buenos Aires
Pain During Labour, Fear of Childbirth
The Effects of the Use of Virgin Mary Herb in Childbirth
This is a study to see if the use of virgin mary herb during birth has an effect on fear, pain and duration during birth. Virgin mary herb is a dry plant and it is believed that when added to water during birth, it makes birth…
- Trial name
- EVMHUBDPFC (NCT06824558)
- Testing
- primiparous pregnant woman following virgin mary, primiparous pregnant
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Medicaid Expansion
Evaluating Quality and Value of US Ambulatory Care Delivered Among Medicaid Expansion/Non-Expansion States, 2012-2015
Quasi-experimental pre-post analysis of the rate of high-value and low-value care services between states that expanded Medicaid and states that did not expand Medicaid January 1, 2014, for adult ambulatory visits, using…
- Trial name
- NCT05319743
- Testing
- Medicaid Expansion
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Lactation
Dietary Lutein and the Retinopathy of Prematurity
The clinical trial aspect of this study is the provision of a lutein supplement to lactating women and compare the amount of lutein in the milk and blood with lactating women who do not receive the lutein supplement.
- Trial name
- NCT00672230
- Testing
- Lutein supplement
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Low Molecular Weight Heparin, Recurrent Implantation Failure
Effect of Low Molecular Weight Heparin in Freeze-thaw Embryo Transfer Cycles in Women With Recurrent Implantation Failure
Recurrent implantation failure (RIF) is considered a tough problem in assisted reproductive technology (ART) without effective treatments. The effect of low molecular weight heparin (LMWH) in pregnancy outcomes is controversial.
- Conditions
- Low Molecular Weight Heparin, Recurrent Implantation Failure, FET, IVF
- Trial name
- NCT06991530
- Testing
- Low Molecular Weight Heparine
- Where
- China
- Volunteers
- 392 people
- Sponsor
- The Second Hospital of Shandong University
Breast Pumping
Assessing the Effect of an Additional 5 Minutes Pumping on Milk Output in the First Days After Delivery
The study hypothesizes that human who are both breastfeeding and pumping in the first days postpartum have more expression volume with an additional 5 minutes of pumping with Maintain program after pumping with the INITIATE…
- Trial name
- NCT06222567
- Testing
- 15 minutes pumping with INITIATE program, 5 minutes extra pumping with MAINTAIN program
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Onze Lieve Vrouwe Gasthuis
PTSD
Pilot Trial of Mobile Mantram Delivery
Mantram Repetition Program (MRP) is a meditation practice that involves silent repetition of a spiritual word, one-pointed attention, and slowing down. It has been shown to help reduce PTSD symptoms among Veterans.
- Trial name
- mMRP (NCT05998967)
- Testing
- Mobile Mantram Repetition Program
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Pancreatic Ductal Adenocarcinoma
Differentiating Tumor-stroma Ratio in Pancreatic Ductal Adenocarcinoma
This study introduces a novel transfer learning-based contrastive language-image pretraining adapter (CLIP-adapter) model for predicting the tumor-stroma ratio (TSR) in pancreatic ductal adenocarcinoma (PDAC) using preoperative…
- Trial name
- NCT06302881
- Volunteers
- 207 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Fetal Growth Restriction, Gut Microbiota
Gut Microbiota, SCFAs and Glucolipid Metabolism in Pregnant Women With Abnormal Fetal Size and Their Newborns
Abnormal fetal size includes fetal growth restriction and fetal macrosomia. Onset is closely related to maternal nutrition metabolism.
- Conditions
- Fetal Growth Restriction, Gut Microbiota, Fetal Macrosomia, Glucolipid Metabolism
- Trial name
- NCT04399434
- Testing
- test gut microbiota, SCFAs and glucolipid metabolism and insulin sensitivity
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Hepatocellular Carcinoma, Radiation Exposure
Y90 Radioembolization Dose Delivery and Radiation Exposure Assessment
The objective of this study is to examine critical aspects of radiation exposure, dose delivery, and systemic yttrium-90 (Y90) exposure related to the infusion of Y90 microspheres for treatment of hepatocellular carcinoma (HCC)…
- Trial name
- NCT03686709
- Testing
- Post therapy PET/CT Imaging
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Tennessee
Preterm Birth
Longitudinal Study of Music Therapy's Effectiveness for Premature Infants and Their Caregivers
Background: Preterm birth has major medical, psychological and socio-economic consequences worldwide. A recent systematic review suggests positive effects of music therapy (MT) on physiological measures of preterm infants and…
- Trial name
- LongSTEP (NCT03564184)
- Testing
- MT during NICU, MT after NICU, Standard care
- Where
- 10 sites in Argentina, Colombia and 3 more
- Volunteers
- 213 people
- Sponsor
- NORCE Norwegian Research Centre AS
Pregnant Women With Singleton Pregnancies
Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies
This is a randomized controlled trial to assess whether a personalized food kit to pregnant women is feasible, improves diet quality, and enhances pregnancy and birth outcomes compared to standard prenatal care.
- Trial name
- HH (NCT07659821)
- Testing
- Food Kit
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Pulmonary Disease, Chronic Obstructive
Characterization of Lung Function Profile of Inhaled Tiotropium + Olodaterol Fixed Dose Combination Compared to Fluticasone Propionate + Salmeterol Fixed Dose Combination in COPD Patients
The objective of the trial is to compare the lung function profile of once daily treatment with tiotropium+olodaterol FDC [2.5/ 5µg and 5/ 5µg] delivered by the RESPIMAT with the lung function profile of twice daily treatment…
- Trial name
- NCT01969721
- Testing
- fluticasone propionate, salmeterol, tiotropium
- Where
- 29 sites in Belgium, Czechia and 6 more
- Volunteers
- 229 people
- Sponsor
- Boehringer Ingelheim