Clinical trials: Delivery
Preterm Birth
Enhanced Nutrition for Preterm Infants
The overall objective of the proposal is to demonstrate the feasibility of providing increased calories and protein in the first week of life to very low birth weight (VLBW) preterm infants.
- Trial name
- NCT03238768
- Testing
- Enhanced Intravenous Nutrition, Standard Intravenous Nutrition
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Minnesota
Intra-amniotic Infection, Preterm Birth
Biomarkers of Intra-amniotic Infection in Women With Preterm Premature Ruptured Amniotic Membranes
The purpose of this study is to investigate the expression of protein biomarkers in cervical vaginal fluid in women with preterm premature rupture of membranes (PPROM)
- Trial name
- PPROM (NCT00701350)
- Where
- 4 sites in United States
- Volunteers
- 79 people
- Sponsor
- ProteoGenix, Inc.
Nicotine Dependence
IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery Rate
This project will examine the impact of the nicotine dose and delivery rate on nicotine's abuse potential, versus its potentially beneficial effects on smoking urges and withdrawal.
- Trial name
- NCT05176418
- Testing
- low dose Nicotine, high dose Nicotine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Cardiovascular Disease
Trial of a Cardiac Rehabilitation Program Delivered Remotely Through the Internet
Cardiac rehabilitation programs (CRP) are a proven treatment for those with ischemic heart disease (IHD). These programs have been demonstrated to improve adherence to regular physical activity, a healthy diet and smoking…
- Trial name
- vCRP (NCT00683813)
- Testing
- vCRP
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- Simon Fraser University
Local Anesthesia of the Skin.
Fractional Laser Assisted Delivery of Anesthetics
The purpose of this study is to assess the efficacy of fractional CO2 laser assisted delivery of topically applied anesthetics (articaine hydrochloride 40 mg/ml and epinephrine 10 μg/ml solution and EMLA cream) regarding to…
- Trial name
- NCT02246179
- Testing
- AFXL, AHES, EMLA cream
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Netherlands Institute for Pigment Disorders
Neonatal Resuscitation, Apnea Neonatal
Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates
Many extremely premature infants require immediate help with breathing after birth. Positive pressure ventilation (PPV) using a device called a T-piece resuscitator is a common method.
- Trial name
- MVP (NCT06849596)
- Testing
- Ventilator derived positive pressure ventilation - V-PPV, T-piece resuscitator (TPR)
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 780 people
- Sponsor
- Michelle Baczynski
Postoperative Pain
Postoperative Pain in Infants
This observational study aims to evaluate skin conductance measurement (SCM) for pain assessment in postoperative newborns. Pain assessment in newborns is challenging due to their inability to communicate, and current methods…
- Trial name
- Poppi (NCT07856615)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Uppsala University Hospital
Preterm Infant Development, COVID - 19
Development of Preterm Infants Born During the COVID-19 Pandemic
This study aims to evaluate differences in cognitive and psychomotor development among preterm infants (born before 34 weeks of gestation) delivered during the COVID-19 pandemic at Hospital de la Santa Creu i Sant Pau, compared…
- Trial name
- NCT07569523
- Testing
- Evaluation of cognitive and psychomotor development through the Bayley Scales Of Infant and Toddler Development and Wechsler Preschool and Primary Scale of Intelligence
- Volunteers
- 120 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Postpartum Hemorrhage
Prophylactic Oxytocin Before Versus After Placental Delivery to Reduce Blood Loss in Vaginal Delivery
Randomized controlled study to assess the efficacy and safety of the timing of administration of prophylactic oxytocin via intramuscular route (before compared to after placental delivery) on blood loss in vaginal delivery.
- Trial name
- NCT03006380
- Testing
- oxytocin
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Emetic Attacks During Caesarean Delivery With Spinal Anesthesia
Comparison Between Drugs for Control of Emetic Attacks During Caesarean Delivery
Single shot spinal anesthesia is widely used for most surgical operations especially in obstetric such as hysterectomy, tubal ligation after vaginal delivery, cesarean and curettage etc.; however, in general, cesarean is…
- Trial name
- NCT06300346
- Testing
- Propofol
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Iron Deficiency, Anemia of Prematurity
Early Versus Late Enteral Iron in Infants Less Than 1301 Grams
Background: Preterm infants are at risk of iron deficiency. The smaller the infants are at birth, the smaller the iron stores at birth and the higher the risk of iron deficiency.
- Trial name
- NCT00458068
- Testing
- Oral administration of ferrous sulphate
- Where
- Germany
- Volunteers
- 126 people
- Sponsor
- University of Ulm
Delivery Modality of BETTER Intervention
The Virtual BETTER Study
The focus of this project is to examine how delivering virtual care impacts health behaviour change for patients with chronic illnesses compared to in-person visits using a chronic disease prevention and screening (CDPS) program…
- Trial name
- NCT05425797
- Testing
- In-Person Prevention Practitioner Visit, Video-Call Prevention Practitioner Visit, Phone Prevention Practitioner Visit
- Where
- Canada
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Pelvic Floor Disorders, Ultrasound Therapy; Complications
Role of Rehabilitation for the Repair of Pelvic Floor Injuries Associated to Vaginal Delivery Identified by 3/4D Transperineal Ultrasound
SUMMARY: (Objective, design, scope of the study, subjects of study, instrumentation, results, conclusions) Objectives: To evaluate if the physiotherapy treatment in pelvic floor dysfunctions, identified by transperineal…
- Conditions
- Pelvic Floor Disorders, Ultrasound Therapy; Complications, Physical Disorder, Obstetric Labor Complications
- Trial name
- NCT03592160
- Testing
- Physiotherapy treatment
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Hospital Universitario de Valme
Degenerative Mitral Valve Disease
Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation
An early feasibility study to evaluate the safety and feasibility of the PLAR Implant and Delivery System to treat severe degenerative mitral regurgitation and to gather preliminary data on its performance thereby providing…
- Trial name
- EXPLORE DMR (NCT04666480)
- Testing
- Transcatheter mitral valve repair
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Polares Medical SA
Postoperative Pain
Ropivacaine Through Continuous Infusion Versus Epidural Morphine for Postoperative Analgesia After Emergency Cesarean Section
The cesarean section is one of the most commonly performed surgeries in the world and it represents 20% of the births in France. Postoperative pain is moderate-to-severe during the first 48 hours after this procedure.
- Trial name
- ROMANCE (NCT02410317)
- Testing
- Ropivacaine, Morphine
- Where
- France
- Volunteers
- 101 people
- Sponsor
- University Hospital, Grenoble
Preterm Labor (24 GA - 32 GA)
Identification of Spontaneous Delivery Markers
The investigators project aims to identify, in pregnant women, discriminating molecules to allow an early detection of women who will spontaneously deliver prematurely, suitable in routine clinical practice.
- Trial name
- TrophY2 (NCT02225717)
- Testing
- Cervicovaginal swab
- Where
- France
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neurodevelopmental Disorders, Autism Spectrum Disorder
Patterns of Neurodevelopmental Disorders
The purpose of this study is to systematically evaluate the results of medical investigations to identify symptom and biological patterns and common etiologies of neurodevelopmental disorders.
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder, Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection, Pediatric Acute-Onset Neuropsychiatric Syndrome
- Trial name
- NCT06213090
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Richard Frye
Hemodynamic Instability
Dobutamine Versus Placebo for Low Superior Vena Cava Flow in Newborns
Low systemic flow as measured by Doppler-echocardiography has been associated with poor neurological outcome. Yet, it has not been systematically evaluated whether the treatment of this hemodynamic condition is beneficial or not.
- Trial name
- NCT01605279
- Testing
- Dobutamine
- Where
- Spain
- Volunteers
- 127 people
- Sponsor
- Adelina Pellicer
Bronchopulmonary Dysplasia, Very Low Birth Weight
Preterm Infant Inhaled Albuterol Dosing
The purpose of this study is to help determine the best dose of inhaled albuterol sulfate in premature babies at risk of developing bronchopulmonary dysplasia (BPD).
- Trial name
- NCT02447250
- Testing
- Varied albuterol dose response
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Oregon Health and Science University
Myocardial Infarction
Bone Marrow Mesenchymal Stem Cells Transfer in Patients With ST-segment Elevation Myocardial Infarction
To investigate the effect and safety of intracoronary autologous bone morrow mesenchymal stem cells (BM-MSCs) transplantation in patients with ST-segment elevation myocardial infarction（ STEMI） .
- Trial name
- Bmmsct (NCT04421274)
- Testing
- Bone marrow mesenchymal stem cells transfer, Best medical treatment, Percutaneous coronary intervention
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Affiliated Hospital of North Sichuan Medical College