Clinical trials: Delivery Outcomes
Pregnant HIV Positive Women, HIV
TB SCReening Improves Preventive Therapy Uptake in Pregnant Women With HIV
Because pregnant women have been excluded from clinical research, including tuberculosis (TB) research, little is known about diagnosing, treating and preventing TB in pregnant women.
- Conditions
- Pregnant HIV Positive Women, HIV, Tuberculosis (TB)
- Trial name
- TB SCRIPT-Moms (NCT07278453)
- Testing
- CRP screening (TB screening intervention arm), Deferred TPT (TPT delivery trial intervention arm)
- Where
- Uganda
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Severe Mental Disorder
Enhancing Community Participation Through Peer-Delivered Decision Support
The purpose of this study is to pilot test a peer-delivered decision support intervention ("peer decision coaching") designed to enhance decision-making about community participation among young adults with serious mental illness…
- Trial name
- NCT06492434
- Testing
- Peer decision coaching
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Temple University
Frailty, Malnutrition
Frail2Fit Study: Online Nutrition and Exercise Support for Older Adults With Frailty
Frail2Fit will explore the feasibility of training volunteers to deliver online nutrition, exercise, and behaviour change (supported self-management) to improve the health of older people after discharge from hospital.
- Conditions
- Frailty, Malnutrition, Sedentary Behavior
- Trial name
- NCT05384730
- Testing
- Group nutrition and exercise support
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Pregnancy and Early Lactation Among Women Living in an Area Endemic for Malnutrition
Balanced Protein-Energy Supplement in Pregnancy and Early Lactation on Birth Outcomes and Growth in Southern Nepal
This project will test the efficacy of a balanced protein energy supplement for daily use during pregnancy and the first 6 months after delivery on the outcomes of pregnancy and growth of infants during the first 6 months of…
- Trial name
- NCT03668977
- Testing
- Fortified balanced protein-energy.
- Where
- Nepal
- Volunteers
- 1,944 people, healthy volunteers welcome
- Sponsor
- George Washington University
Fetal Kick Counting
Promoting Fetal Movement Monitoring: Improving Birth Outcomes
The purpose of the study is to find out the best way to help pregnant women keep track of their baby's movements. During pregnancy, feeling your baby's movements is normal.
- Trial name
- NCT01844011
- Testing
- Daily electronic reminders
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mercy Medical Center
Premature Birth of Newborn
Premature Infant Exposure to Noise Generated by Respiratory Support
Infants in neonatal intensive care units are increasing exposed to non-invasive ventilatory support modes (nasal continuous positive airway pressure - NCPAP and high flow nasal cannula: >1 L/min flow - HFNC).
- Trial name
- NCT01748214
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Virginia
Evidence-Based Practice, Labor; Prolonged, Second Stage
Open-glottis Pushing Technique Versus the Valsalva Pushing Technique in the Second Stage of Labor
Pushing has been discussed for decades, primarily in terms of facilitating care in the second stage of labor and maternal/fetal outcomes. Valsalva-type pushing is the pushing performed by a pregnant woman by holding her breath.
- Conditions
- Evidence-Based Practice, Labor; Prolonged, Second Stage, Labor, Fetal Acidosis Complicating Labor and Delivery
- Trial name
- NCT06210087
- Testing
- Spontaneous pushing technique
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Substance-Related Disorders, Substance Use
Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care
Alcohol and other drug use is common among people living with HIV in South Africa and is associated with worse engagement in HIV care.
- Conditions
- Substance-Related Disorders, Substance Use, Substance Use Disorders, Stigma, Social
- Trial name
- NCT05907174
- Testing
- Siyakhana - P
- Where
- South Africa
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Preterm Birth, Preeclampsia
Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH)
Aspirin is recommended in high risk patients to reduce the risk of preeclampsia and preterm birth, which are leading causes of both maternal and neonatal morbidity and mortality, but up to 20% will have these adverse outcomes…
- Trial name
- DASH (NCT06826859)
- Testing
- Daily aspirin (ASA), Split dose aspirin (ASA)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Thomas Jefferson University
Infertility, IVF
Health of Babies Born From IVF Versus IVM at 5 Years Old
The investigators conduct a long-term follow-up at five years on offspring born from our randomized controlled trial (RCT) to investigate whether or not there is any difference in developmental outcomes in children born after…
- Conditions
- Infertility, IVF, IVM, Development, Child
- Trial name
- FM-BABIES-5Y (NCT06369415)
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3 and behavioural screening according to Strength and Difficulties Questionnaires (SDQ's)
- Where
- Vietnam
- Volunteers
- 214 people
- Sponsor
- Mỹ Đức Hospital
ISS, SGA
Comparison of Weekly Somatrogon to Daily Genotropin in Children Born Small for Gestational Age or With Idiopathic Short Stature.
This study is a randomized, open-label, active controlled, parallel group study comparing the efficacy and safety of once weekly Somatrogon to daily Growth Hormone (Genotropin) in pre-pubertal children with short stature either…
- Trial name
- MISSION (NCT07226089)
- Testing
- Somatrogon, Genotropin
- Where
- 32 sites in United States, France and 3 more
- Volunteers
- 254 people
- Sponsor
- Rabin Medical Center
Hypothyroxinemia
Supplemental Thyroxine Treatment for Preterm Infants With Hypothyroxinemia
In order to determine the efficacy and safety of thyroxine replacement, a randomized clinical trial of thyroxine supplementation for VLBW infant with hypothyroxinemia during the first month of age is conducted.
- Trial name
- NCT00565890
- Testing
- thyroxine
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Tokyo Women's Medical University
Perinatal Outcomes, Preterm Birth
Continuous Non-invasive Electrophysiological Monitoring in High Risk Pregnancies
The goal of this single centre cohort intervention study with historical controls, is to investigate the effect of implementing continuous antepartum electrophysiological CTG (eCTG) monitoring at the Obstetric High Care (OHC), on…
- Conditions
- Perinatal Outcomes, Preterm Birth, High Risk Pregnancy
- Trial name
- NIEM-O (NCT06151613)
- Testing
- continuous eCTG monitoring using the NFMS
- Where
- Netherlands
- Volunteers
- 1,911 people
- Sponsor
- Maxima Medical Center
Depression, Child Development
Improving Preterm Outcomes by Safeguarding Maternal Mental Health
The investigators' goal is to optimize the developmental outcomes of preterm infants by preventing depression and improving functioning among their mothers during the critical first year of life.
- Trial name
- NCT01892982
- Testing
- Problem Solving Education tailored to NICU
- Where
- 4 sites in United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Health Behavior
Effect of Social Accountability on Improving Service Delivery and Outcomes in the Public Sector in Uttar Pradesh, India
In several low and middle-income countries, Social Accountability (SA) interventions have been introduced as an innovative approach to governance, aiming to improve delivery of public services.
- Trial name
- D0168 (NCT02879708)
- Testing
- Information Only, Information and Facilitation
- Where
- India
- Volunteers
- 105,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Pregnancy Related, Pregnancy Complications
The Heartland Study
The Heartland Study is a prospective, observational study that will enroll up to 2,600 pregnant participants across the Heartland States in the U.S..
- Conditions
- Pregnancy Related, Pregnancy Complications, Birth Defect, Gestational Age and Weight Conditions
- Trial name
- NCT05492708
- Where
- 4 sites in United States
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- Heartland Health Research Alliance
Vitamin D3 Deficiency, Prematurity
Vitamin D and Health Outcomes in Preterm Born Population
Improved survival of very preterm newborn population during the last decades has challenged us neonatologists to study and improve nutritional practices including vitamin D (VitD) supplementation.
- Conditions
- Vitamin D3 Deficiency, Prematurity, Lung Diseases, Heart Rate Variability
- Trial name
- ViDePrePop (NCT04342078)
- Testing
- Vitamin D
- Where
- Finland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Premature Birth, Infant Development
Neonatal Experience of Social Touch
The purpose of this randomised control trial is to determine the efficacy of CT-optimal touch (gentle stroking at 3cm/s) for newborn's who require a heel prick.
- Conditions
- Premature Birth, Infant Development, Pain
- Trial name
- NEST (NCT05039918)
- Testing
- Affective touch
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Pregnant Women With Singleton Pregnancies
Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies
This is a randomized controlled trial to assess whether a personalized food kit to pregnant women is feasible, improves diet quality, and enhances pregnancy and birth outcomes compared to standard prenatal care.
- Trial name
- HH (NCT07659821)
- Testing
- Food Kit
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Cesarean Section
Comparing French Ambulatory and MISGAV-LADACH C-Section Techniques
In the last decades cesarean section rates are getting higher in many countries. The rise in those rates encourages obstetricians to improve operative techniques for a better maternal and fetal outcome.
- Trial name
- MLC (NCT03741907)
- Testing
- FAUCS, MLC
- Where
- Tunisia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar