Clinical trials: Delivery Outcomes
Prematurity
Care Outcomes in Preterm Infants Following the Implementation of Family-centered Interventions
The proposed study evaluates the effects of two family-centered interventions on the length of stay and outpatient visits and growth of preterm infants.The interventions are 1) the Close Collaboration with Parents training for…
- Trial name
- NCT05765136
- Where
- Finland
- Volunteers
- 30,000 people
- Sponsor
- University of Turku
Preterm, Neurodevelopmental Disorder
Biomarkers, Neurodevelopment and Preterm Infants
Approximately 2% of neonates in the US are born very preterm. Preterm births are associated with impaired cognitive, language and motor function, and increased risk for autism spectrum disorders.
- Conditions
- Preterm, Neurodevelopmental Disorder, Epigenetic Changes
- Trial name
- NCT02557191
- Testing
- Observational study
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Montefiore Medical Center
Premature Infants
Effect of Erythropoietin on Neurodevelopmental Outcomes in Very Preterm Infants With Intraventricular Hemorrhage
Erythropoietin (EPO) has been shown to be neurotrophic and neuroprotective in several animal models and some clinical studies. Our hypothesis is that EPO could improve long-term neurological outcomes in very preterm infants with…
- Trial name
- NCT03914690
- Testing
- Erythropoietin, Normal saline
- Where
- China
- Volunteers
- 316 people
- Sponsor
- Zhengzhou University
Psychological Well-being, Childbirth
The Effect of Trauma Informed Care in Childbirth
The aim of this study is to determine the effect of supportive care based on trauma informed care during childbirth on perinatal mental health outcomes.
- Conditions
- Psychological Well-being, Childbirth, Care Pattern, Maternal
- Trial name
- NCT05662176
- Testing
- Experimental: Supportive Care based on trauma informed care, Standart care
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Mersin University
Hydrops Fetalis, Birth Defect
Hydrops: Diagnosing & Redefining Outcomes With Precision Study
This is a national, prospective study designed to investigate the genetic etiologies of non-immune hydrops fetalis (NIHF) and other birth defects.
- Conditions
- Hydrops Fetalis, Birth Defect, Fetal Anomaly
- Trial name
- HyDROPS (NCT03412760)
- Testing
- Exome sequencing
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of California, San Francisco
Perinatal Outcomes, Preterm Birth
Continuous Non-invasive Electrophysiological Monitoring in High Risk Pregnancies
The goal of this single centre cohort intervention study with historical controls, is to investigate the effect of implementing continuous antepartum electrophysiological CTG (eCTG) monitoring at the Obstetric High Care (OHC), on…
- Conditions
- Perinatal Outcomes, Preterm Birth, High Risk Pregnancy
- Trial name
- NIEM-O (NCT06151613)
- Testing
- continuous eCTG monitoring using the NFMS
- Where
- Netherlands
- Volunteers
- 1,911 people
- Sponsor
- Maxima Medical Center
Perinatal and Neonatal Outcomes in Pregnancies With Type 2 Diabetes Mellitus (T2DM)
Antenatal Myo-inositol Supplementation in Pre-existing Diabetes
This feasibility pilot study aims to gather data that can guide the design of a larger, more comprehensive trial to establish the effects of myo-inositol supplementation on supporting healthy outcomes in pregnancies complicated…
- Trial name
- AMulet (NCT07241221)
- Testing
- Myo-inositol and folic acid supplement, Folic acid supplement
- Where
- Singapore
- Volunteers
- 182 people
- Sponsor
- National University Hospital, Singapore
Type 1 Diabetes
Glycemic Control and Osteohealth in Adults Living With Type 1 Diabetes
Bone damage is frequently observed in type 1 diabetes, and hyperglycemia is associated with an increased risk of fracture. This pilot study in 25 people living with type 1 diabetes aims to determine whether the introduction of an…
- Trial name
- GLYCO-OSTEO (NCT06158503)
- Testing
- AID
- Where
- 2 sites in Canada
- Volunteers
- 25 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Early Labor
Membrane Sweeping in Early Labor and Delivery Outcomes
Membrane sweeping is a routine procedure in obstetrics in term patients. It has been shown to be effective in decreasing post term gestation and in increasing rate of spontaneous vaginal delivery when used in setting of induction…
- Trial name
- NCT03517696
- Testing
- Membrane sweeping
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Fetal Kick Counting
Promoting Fetal Movement Monitoring: Improving Birth Outcomes
The purpose of the study is to find out the best way to help pregnant women keep track of their baby's movements. During pregnancy, feeling your baby's movements is normal.
- Trial name
- NCT01844011
- Testing
- Daily electronic reminders
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mercy Medical Center
Neonatal Acidemia and Hypoxia
Evaluation of Neonatal Acute Hypoxia at Delivery Using Fetal Physiology and Eucapnic pH Assessment
This study aims to improve understanding of how fetuses respond to oxygen deprivation during labor by re-evaluating cardiotocography (CTG) recordings using a physiology-based interpretation approach and comparing these findings…
- Trial name
- NOAH (NCT07629271)
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cesarean Delivery, Postpartum Hemorrhage (PPH)
Topical Tranexamic Acid to Reduce Blood Loss During Cesarean Delivery
The goal of this clinical trial is to learn whether applying topical tranexamic acid (TXA) directly to the uterine incision during cesarean delivery can reduce surgical bleeding compared to placebo.
- Conditions
- Cesarean Delivery, Postpartum Hemorrhage (PPH), Intraoperative Blood Loss, Hemostasis
- Trial name
- NCT07362992
- Testing
- Tranexamic Acid (Topical)
- Where
- 4 sites in Israel
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Prematurity, Respiratory Disease
Prematurity and Respiratory Outcomes Program (PROP)
In survivors of extreme prematurity to 36 weeks Post Menstrual Age (PMA), specific biologic, physiologic and clinical data obtained during the initial hospitalization will predict respiratory morbidity as defined by respiratory…
- Trial name
- PROP (NCT01435187)
- Where
- 13 sites in United States
- Volunteers
- 835 people
- Sponsor
- University of Pennsylvania
Prematurity
Ultrasound, Peds Body Composition, and Neurodevelopmental Outcomes
The overall objective of the proposal is to evaluate the ability of ultrasound to predict the body composition of toddlers in the outpatient clinical setting and to evaluate the relationship between body composition and…
- Trial name
- NCT03479515
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Minnesota
Alcohol Use Disorder, Alcohol Abuse
Internet-delivered Cognitive Behavior Therapy for Problematic Alcohol Use in a Working Life Setting
Internet-based cognitive behavioral treatment (ICBT) for mental health issues has been successfully implemented in routine health care and research indicates that ICBT can also be applied to decrease problematic alcohol use in…
- Trial name
- Simba (NCT06774716)
- Testing
- Internet-based cognitive behavioural treatment and relapse prevention, Face-to-face cognitive behavioural treatment or short-term psycodynamic therapy with relapse prevention
- Where
- Sweden
- Volunteers
- 38 people
- Sponsor
- Stockholm University
Education, Maternal Health
Simulation-Based Childbirth Training and Midwives' Outcomes
This randomized controlled study aims to evaluate the effect of simulation-based childbirth management training on safe motherhood practices and intrinsic motivation among midwives.
- Trial name
- NCT07543133
- Testing
- Simulation-Based Childbirth Management Training
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Pregnancy, Health Literacy
Mobile Assisted Education on Prenatal Health
This study aims to evaluate the effect of mobile-assisted education on prenatal health literacy, health behaviors, and childbirth outcomes among primigravida women
- Conditions
- Pregnancy, Health Literacy, Mobile Assisted Education, Health Behavior
- Trial name
- NCT07900152
- Testing
- Mobile-Assisted Education
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Benha University
Respiratory Disease
Hybrid Pulmonary Rehabilitation Study
Pulmonary rehabilitation is an exercise and education programme that helps improve breathlessness and quality of life for people living with lung and breathing problems.
- Trial name
- NCT05881590
- Testing
- Hybrid pulmonary rehabilitation
- Where
- United Kingdom
- Volunteers
- 69 people
- Sponsor
- Anglia Ruskin University
Infant, Newborn, Infant, Small for Gestational Age
Hydrocortisone for BPD
The Hydrocortisone and Extubation study will test the safety and efficacy of a 10 day course of hydrocortisone for infants who are less than 30 weeks estimated gestational age and who are intubated at 14-28 days of life.
- Conditions
- Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Infant, Premature
- Trial name
- NCT01353313
- Testing
- Hydrocortisone
- Where
- 20 sites in United States
- Volunteers
- 800 people
- Sponsor
- NICHD Neonatal Research Network
Cesarean Delivery Affecting Fetus or Newborn, Labor (Obstetrics)--Complications
Two Previous Cesarean and Vaginal Birth Before and After Starting Training and Protocols
In 2015 ObGyn Dept of Santo Spirito Hospital in Pescara (Italy) started protocol for previous CS vaginal birth. In 2021 was started a protocol for training on obstetric emergencies and protocol on two previous cesarean was…
- Conditions
- Cesarean Delivery Affecting Fetus or Newborn, Labor (Obstetrics)--Complications, Hemorrhagic Complications
- Trial name
- TOLA2C Train (NCT07258459)
- Testing
- Acceptance, rate of vaginal birth and safety
- Where
- 2 sites in Italy
- Volunteers
- 2,016 people
- Sponsor
- G. d'Annunzio University