Clinical trials: Delivery Systems
Hodgkin's Disease, Lymphoma, Non-Hodgkin
Reproducibility of an Immobilization Device (BodyFIX) - Hodgkins/Lymphoma
Radiation therapy has a well-established role in the treatment of Hodgkin's Disease and non-Hodgkin's Lymphoma. With technological developments, 3-D Dimensional (3D) planning has evolved as a highly precise treatment planning…
- Trial name
- NCT00232440
- Testing
- BodyFIX
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Hepatitis C, Chronic, Hepatitis C
Epidemiology of Occult Hepatitis C Virus Infection in Patients Born Before 1969 in the Hospital Setting: a Spontaneous Opportunistic Screening Initiative.
The goal of this monocentric prospective observational study is to evaluate the prevalence of unknown hepatitis C virus chronic infection in general population born before january 1st 1968 in Italy.
- Conditions
- Hepatitis C, Chronic, Hepatitis C, Hepatitis
- Trial name
- ERADIcATE (NCT05813691)
- Testing
- Meridan Bioscience Point of Care test against HCV antibodies
- Volunteers
- 4,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Degenerated Mitral Regurgitation
Safety and Effectiveness Study of SQ-Kyrin TMVr System for Degenerated Mitral Regurgitation
To verify the safety and effectiveness of transcatheter mitral valve clip delivery system and steerable guide catheter produced by Shanghai Shenqi Medical Technology Co., Ltd.in patients with moderate-severe or severe degenerated…
- Trial name
- NCT06467110
- Testing
- transcatheter mitral valve clip delivery system and steerable guide catheter (Shenqi Medical)
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Shanghai Shenqi Medical Technology Co., Ltd
Asthma, Adolescent Behavior
The Effectiveness of Peer-education Programs for Adolescents Diagnosed With Asthma
The research was planned in a randomized controlled trial to evaluate the effect of technology-based education provided by peers and adults to children diagnosed with asthma in the 14-17 age group.
- Conditions
- Asthma, Adolescent Behavior, Self Efficacy, Peer Support and Chronic Disease
- Trial name
- NCT06392490
- Testing
- Technology Based Asthma Program
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Visual Disorder
Premavision Cohort Follow-up
This study aim at following a cohort of prematurely born infants at 18 months corrected age, 4 and 7 years of age. This cohort had an evaluation of visual maturation at term equivalent age (TEA) with factors associated with…
- Trial name
- PrmvsionSuiv (NCT03207477)
- Testing
- Visual acuity measurement
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Multiple Sclerosis
Patient Satisfaction Study of Single-Use Autoinjector for the Delivery of Pre-Filled Avonex Syringe
Determine patient satisfaction with the single-use autoinjector for the delivery of pre-filled Avonex syringe.
- Trial name
- NCT00915577
- Testing
- Interferon beta-1a, Single-use autoinjector
- Volunteers
- 74 people
- Sponsor
- Biogen
Influenza, Respiratory Tract Infections
Patient Portal Flu Vaccine Reminders_RCT 5 (LADHS)
This trial is taking place in Los Angeles, CA at clinics within the Los Angeles Department of Health clinics. The study design is a comparative effectiveness trial design.
- Trial name
- LADHS (NCT05535777)
- Testing
- Enhanced texts with Callback by a Person, Enhanced Bidirectional Texts
- Where
- 2 sites in United States
- Volunteers
- 246,295 people
- Sponsor
- University of California, Los Angeles
Peritonitis
Clinical Relevance of the Reverse Lipopolysaccharide Transport Pathway in Patients With Acute Peritonitis
When there is infection in the intra-abdominal area, bacteria secrete toxins that are absorbed by the peritoneum. These toxins then bind to lipoproteins (which carry cholesterol in the blood) and are eliminated by the liver.
- Trial name
- LIPS (NCT04126577)
- Testing
- blood samples
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Perinatal Depression, Chronic Pain
CSF/Serum Biomarkers in Predicting PND/Persistent Pain After Cesarean
The aim is to investigate if inflammatory biomarkers in the blood and cerebrospinal fluid (CSF) are associated with the development of perinatal depression and/or persistent pain after cesarean delivery.
- Trial name
- NCT04271072
- Testing
- No intervention
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Duke University
Type 1 Diabetes
Transdermal Basal Insulin Patch Study in Type 1 Diabetes
This study is designed to evaluate the pharmacokinetics/pharmacodynamics of an investigational basal insulin patch in type 1 diabetes patients.
- Trial name
- NCT00519623
- Testing
- PassPort(R) Transdermal Insulin Delivery System
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Altea Therapeutics
Preterm Birth, Low Birthweight Neonate
Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial
The ground-breaking Prevention of Prematurity and Xylitol (PPaX) cluster randomized controlled clinical trial was conducted in Lilongwe, Malawi and enrolled approximately 10,069 pregnant individuals seeking to evaluate the impact…
- Conditions
- Preterm Birth, Low Birthweight Neonate, Periodontitis, Gingivitis
- Trial name
- XaPPP (NCT07424846)
- Testing
- Xylitol Chewing gum, Sorbitol chewing gum
- Where
- Malawi
- Volunteers
- 6,000 people
- Sponsor
- University of Washington
Spina Bifida or Spinal Dysraphism
Vitamin B9 Supplementation Recommendations in Rennes CHU
The study objective is to assess the knowledge and the follow-up of vitamin B9 supplementation recommendations for women in the periconceptional period to prevent neural tube closure defects.
- Trial name
- QUALI B9 (NCT04195542)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 1,284 people
- Sponsor
- Rennes University Hospital
Infant, Newborn, Diseases, Hypoxia
Environmental or Nasal Cannula Oxygen for Preterm Infants Receiving Oxygen Therapy: a Randomized Cross-over Pilot Study
The purpose of this study is to determine if, in preterm infants < 37 weeks' gestation at birth receiving oxygen without ventilatory/CPAP support, oxygen environment (OE) compared with nasal cannula oxygen (NC), will decrease the…
- Trial name
- ECO (NCT02794662)
- Testing
- Oxygen Environment, Nasal Cannula Oxygen
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Human Immunodeficiency Virus, HIV
Support for Adolescents Living With HIV in South Africa
This is a cluster randomized controlled trial determining the effectiveness of in-person or mHealth-based adolescent-friendly transition interventions compared to standard care on retention in care and viral suppression among…
- Trial name
- InTSHA VIP (NCT06035445)
- Testing
- In-person adolescent-friendly service (iPAS) intervention, mHealth (InTSHA) intervention, Standard of Care
- Where
- South Africa
- Volunteers
- 570 people
- Sponsor
- Emory University
Ovarian Cancer, Ovarian Tumor
AI Analysis of CT Scans to Classify Ovarian Tumours as Benign, Borderline or Malignant Before Surgery
The goal of this observational study is to learn if a computer program can tell what type of ovarian tumour a person has from a CT scan taken before surgery. The program uses artificial intelligence (AI).
- Conditions
- Ovarian Cancer, Ovarian Tumor, Borderline Ovarian Tumor
- Trial name
- OvaClass (NCT07883551)
- Where
- 7 sites in Belgium, Netherlands
- Volunteers
- 1,300 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Hepatitis B
Anti-Hep B Antibodies at Age 12 to 18 Months After Hep B Vaccine at Birth and DTaP-IPV-Hep B-PRP-T Hexavalent Vaccine Concomitantly With Prevnar® at 2, 4 and 6 Months of Age
Primary Objective: To describe the persistence of Hep B antibodies (Ab) at 12 to 18 months of age following a three-dose infant primary series vaccination of either Hexaxim®/Hexyon®/Hexacima® or Infanrix® hexa at 2, 4 and 6…
- Trial name
- NCT02610348
- Testing
- DTaP-IPV-HB-PRP~T and Pneumococcal polysaccharide vaccines, DTaP-HB-IPV and Pneumococcal polysaccharide vaccines
- Where
- 2 sites in Thailand
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Neonatal Hypoglycemia, Metabolic Complication
Pasteurised Donor Human Milk Supplementation for Term Babies
PRESENT is a multi-center randomised controlled trial that aims to assess whether access to pasteurized donor human milk as supplementary nutrition in the first five days of life for term infants born to women with diabetes in…
- Conditions
- Neonatal Hypoglycemia, Metabolic Complication, Cows Milk Allergy, Hospital Length of Stay
- Trial name
- PRESENT (NCT06993103)
- Testing
- Standard care Cow's milk based formula, Dietary Supplement: PDHM Pasteurised Donor Human Milk
- Where
- 4 sites in Australia
- Volunteers
- 1,444 people
- Sponsor
- The University of Queensland
Alzheimer Dementia (AD), Diabete Type 2
Brain Blood Flow and Sugar Transport in Alzheimer's Disease With and Without Diabetes - A Pilot Imaging Study
Alzheimer's disease is the most common cause of dementia and affects a growing number of older adults. Although harmful proteins build up in the brain, we still do not fully understand why some brain regions are affected earlier…
- Trial name
- PETTAU (NCT07482072)
- Testing
- [18F]FDG PET, [11C]PIB
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Myositis, Idiopathic Inflammatory Myopathy
MYOPROSP - a Prospective Cohort Study in Myositis
Adult patients with suspected or confirmed idiopathic inflammatory myopathy (IIM) will be recruited. Patients will be approached, consented, have baseline demographics, diagnostics and disease activity measures recorded, and…
- Trial name
- MYOPROSP (NCT02468895)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Manchester
Type2 Diabetes
OP5-005 Using Omnipod 5 in Adults With Type 2
This is a single arm, multi-center, prospective study that will evaluate the safety and efficacy of the Omnipod 5 Automated Insulin Delivery System in adults with type 2 diabetes requiring insulin therapy.
- Trial name
- SECURE-T2D (NCT05815342)
- Testing
- Omnipod 5 Automated Glucose Control System
- Where
- 21 sites in United States
- Volunteers
- 343 people
- Sponsor
- Insulet Corporation
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