Clinical trials: Delivery Systems, open to volunteers
Diabetes Mellitus, Type 1
Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery
This investigator-initiated study will enroll about 30 adults 18 to 65 years of age with type 1 diabetes (T1D) who are using the Tandem t:slim X2 insulin pump or Tandem Mobi insulin pump with Control-IQ or Control-IQ+ technology…
- Trial name
- INHALE-AIDEx (NCT06880835)
- Testing
- Control IQ + sleep or exercise activity with TI
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Jaeb Center for Health Research
Cancer Awareness and Prevention Education, Breast Cancer Awareness
A Single-Arm Interventional Trial of Pepper- Robot Delivered Cancer Education for Adults With Intellectual Disability
Individuals with Intellectual disability face numerous barriers to cancer education, awareness and screening, including communication challenges, anxiety, and a lack of accessible educational resources.
- Conditions
- Cancer Awareness and Prevention Education, Breast Cancer Awareness, Intellectual Disabilities (F70-F79)
- Trial name
- Pep-SMARTID (NCT07477938)
- Testing
- Robot delivered Education
- Where
- Ireland
- Volunteers
- 25 people
- Sponsor
- National University of Ireland, Galway, Ireland
Suspected Stroke
Early Initiated Ambulance-delivered Levetiracetam and Headposition in Hyper-acute Stroke Trial
This is an investigator initiated and conducted, multicentre, ambulance-delivered, prospective, randomised, open-label, blinded outcome (PROBE) study.
- Trial name
- EAST (NCT06773364)
- Testing
- Levetiracetam, Guide-recommended management, The lying flat (0°) head position
- Where
- 2 sites in China
- Volunteers
- 2,423 people
- Sponsor
- Shanghai East Hospital
Food Allergy
Pectin Intervention Study and Long-term Follow-up in Lipid Transfer Proteins Allergic Patients
Pectins are dietary fibers that have shown a health effect on patients with food allergy, as they are capable of modifying the composition of gastrointestinal microbiota, and producing an immunomodulatory effect.
- Trial name
- PI23/00820 (NCT06558526)
- Testing
- Apple pectin (DE 57%)
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Intracerebral Hemorrhage, Stroke-Associated Pneumonia (SAP)
An Open-Label, Dose-Escalation Study on the Safety, Tolerability and Preliminary Efficacy for Preventing SAP by Intravenous Pump-Delivered Propranolol in Patients With ICH
This is an open-label, dose-escalation study on the safety, tolerability and preliminary efficacy for preventing stroke-associated pneumonia of propranolol in patients with intracerebral hemorrhage.
- Trial name
- PROCHASE-DoE (NCT07528235)
- Testing
- Intravenous Pump-Delivered Propranolol
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Tang-Du Hospital
Liver Diseases
Veteran-Centered Care for Advanced Liver Disease (Vet-CALD)
Advanced liver disease is a serious illness that disproportionately affects Veterans, many of whom hope for curative liver transplantation.
- Trial name
- Vet-CALD (NCT06068491)
- Testing
- Vet-CALD
- Where
- 8 sites in United States
- Volunteers
- 450 people
- Sponsor
- VA Office of Research and Development
Environmental Exposure, Pregnancy Related
Prenatal Education on Environmental Exposures During Pregnancy Study (PEEPS)
The purpose of this project is to reduce maternal environmental exposures to toxicants through a patient education program designed to help pregnant women learn about exposure through consumption of contaminated seafood and to be…
- Conditions
- Environmental Exposure, Pregnancy Related, Preterm Birth, Chronic Respiratory Disease
- Trial name
- PEEPS (NCT07758114)
- Testing
- Educational Intervention
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Brain Injury, Cognition
Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD
Veterans with mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD) commonly experience cognitive impairments including attention and executive function deficits that interfere with their ability to engage…
- Conditions
- Brain Injury, Cognition, PTSD, Intervention
- Trial name
- NCT05380050
- Testing
- Goal Management Training plus Attention Training, Brain Health Workshop and National Geographic Movies
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development
Human Papillomavirus Type 16, Cervical Intraepithelial Neoplasia Grade II
HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia
The primary goal of this phase I open label study is to determine the safety and tolerability of pNGVL4aCRTE6E7L2 DNA vaccine, as administered by intramuscular (IM) injection with TriGrid™ electroporation to both HIV- or HIV+…
- Conditions
- Human Papillomavirus Type 16, Cervical Intraepithelial Neoplasia Grade II, Cervical Intraepithelial Neoplasia, Grade III
- Trial name
- NCT04131413
- Testing
- pNGVL4aCRTE6E7L2
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins