Clinical trials: Dementia, Familial
Motor Neuron Disease, Familial, Amyotrophic Lateral Sclerosis With Dementia
Cortico-Spinal tDCS as Rehabilitative Intervention in Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (ALS) is a motor neuron disease, which is a group of neurological disorders that selectively affect motor neurons, the cells that control voluntary muscles of the body.
- Trial name
- tDCS_MND_2 (NCT04293484)
- Testing
- Anodal bilateral motor cortex and cathodal spinal tDCS
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Alzheimer Disease, Hearing Loss
Hearing Instruments in Alzheimer's Disease
There is a strong connection between hearing loss and cognitive impairment, particularly dementia, in old age. Worldwide, dementia affects approximately 5% of persons over the age of 65 years.
- Trial name
- HIAD (NCT02294513)
- Testing
- Standard audiologic rehabilitation (incl. HI)
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Phonak AG, Switzerland
Dementia
Behavioral Sleep Intervention in Adult Family Homes
Sleep disturbances are widespread among demented residents of board and care homes and are a leading cause for transfer into nursing homes.
- Trial name
- NCT00393627
- Testing
- Sleep Education Program
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Washington
Burnout, Professional, Caregivers
The Effects of a Meditation Intervention on the Psychological Burden of Long-Term Care Professionals and Family Caregivers
The goal of this clinical trial is to learn whether a brief, digitally-supported mindfulness program can reduce caregiver burnout in professional caregivers (such as nurses, case managers, and care workers) and informal family…
- Conditions
- Burnout, Professional, Caregivers, Caregivers Burnout, Stress, Psychological
- Trial name
- NCT07188454
- Testing
- Mindfulness-Based Digital Intervention (AIZEN Program)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Health Research Institutes, Taiwan
Dementia
Supporting Caregivers of PWD and Identifying an Effective Intervention to Reduce Their Depressive Symptoms
Effective clinical management of chronic conditions like depressive symptoms of caregivers actually requires a sequence of interventions, each adapts to responses to prior interventions, and hence multiple intervention decisions…
- Trial name
- NCT05634317
- Testing
- Smartphone delivered Behavioral activation, Smartphone delivered Mindfulness
- Where
- Hong Kong
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Dementia
The Development and Evaluation of a Culturally Tailored Support Group Program on the Psychosocial Wellbeing of Family Caregivers of Individuals Living With Dementia in Hong Kong
Hong Kong is also facing the increasing prevalence of dementia. Evidence states that dementia caregivers have poor psychosocial wellbeing including stress, depression and anxiety.
- Trial name
- NCT04334200
- Testing
- Cultivate yourself: support for caregivers of dementia persons
- Volunteers
- 49 people
- Sponsor
- Chinese University of Hong Kong
Amyloidosis, Amyloid Cardiomyopathy
Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy
Phase 3 efficacy and safety study to evaluate acoramidis (AG10) HCl 800 mg administered orally twice a day compared to placebo in subjects with symptomatic Transthyretin Amyloid Cardiomyopathy (ATTR-CM).
- Conditions
- Amyloidosis, Amyloid Cardiomyopathy, Transthyretin Amyloidosis, Cardiomyopathies
- Trial name
- ATTRibute-CM (NCT03860935)
- Testing
- acoramidis
- Where
- 104 sites in United States, Australia and 16 more
- Volunteers
- 632 people
- Sponsor
- Eidos Therapeutics, a BridgeBio company
Anxiety, Agitation
Family Videos and Virtual Reality in Intensive Care Patients
This randomized controlled trial was conducted to evaluate the effects of family videos and virtual reality-based nature videos on anxiety, agitation, pain, and vital signs in adult intensive care unit patients.
- Conditions
- Anxiety, Agitation, Pain, Physiological Parameters
- Trial name
- NCT07794696
- Testing
- Family Video.Participants watched a five-minute video prepared by their family members twice daily on the second and third days of intensive care.
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Sennur Kula Şahin
Alzheimer Disease, Family Members
Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease
Alzheimer's disease (AD) is characterized by significant memory loss, toxic protein deposits (amyloid and tau) in the brain, and changes in the gamma frequency band on EEG.
- Trial name
- NCT05776641
- Testing
- GENUS
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital