Clinical trials: Dementia, completed
Transcranial Direct Current Stimulation, Dementia
DAOIB Combined With tDCS for Early-phase Dementia
This is a 24-week randomized, double-blind, placebo-controlled trial. We will enroll patients with aMCI or mild AD. All patients will receive 2 weeks of tDCS (5 sessions per week, 10 sessions in total) during the first 2 weeks of…
- Trial name
- NCT04737096
- Testing
- DAOIB, tDCS
- Where
- Taiwan
- Volunteers
- 97 people
- Sponsor
- Chang Gung Memorial Hospital
Dementia, Pain
Pain in Patients With Dementia and Behavioural Disturbances
In nursing homes (NHs) 80% of the patients have dementia, between 60%-80% exhibit behavioural disturbances (BPSD), and more than 60% have pain. Both pain and BPSD is more common in those with severe dementia.
- Conditions
- Dementia, Pain, Agitation
- Trial name
- NCT01021696
- Testing
- Paracetamol, Morphine, Buprenorphine plaster
- Where
- 18 sites in Norway
- Volunteers
- 352 people
- Sponsor
- University of Bergen
Alzheimer's Disease
A Multiple Ascending Dose Study in Healthy Volunteers and Patients With Alzheimer's Disease
A Phase 1b Multiple Ascending Dose Study of the Safety and Tolerability of BMS-984923 in Healthy Older Adults and Patients with Alzheimer's Disease
- Trial name
- NCT05804383
- Testing
- BMS-984923
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Allyx Therapeutics
Mild Cognitive Impairment, Dementia
Short-term Automated Longitudinal Analysis of Speech and Language in Cognitive Impairment
Validate speech analysis AI models: To contrast the accuracy of acceXible's platform as a screening tool in the detection of people with cognitive impairment and mild dementia.
- Trial name
- NCT05340218
- Testing
- Speech analysis
- Where
- Spain
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Accexible
Inactivity, Physical
BCT Intervention For Walking Habit Among Caregivers of People With AD/ADRD
This 12-week trial will test the efficacy of a multi-component, personalized text-message delivered behavior change technique (BCT) intervention to encourage habitual physical activity (defined as regular walking of 1,000 or more…
- Trial name
- NCT06803797
- Testing
- Behavior Change Technique Package
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Alzheimer Disease
Multiple Dose Safety Study of NPT088 in Patients With Mild to Moderate Probable Alzheimer's Disease
The purpose of the study is to evaluate the safety and tolerability of multiple doses of NPT088 in patients with mild to moderate probable Alzheimer's Disease.
- Trial name
- NCT03008161
- Testing
- NPT088
- Where
- 23 sites in United States
- Volunteers
- 83 people
- Sponsor
- Proclara Biosciences, Inc.
Familial Frontotemporal Dementia
Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects
This study is being done to learn more about normal thinking and behavior, mild thinking and behavior problems, Frontotemporal Dementia and other forms of dementia in families in which one or more relatives have a mutation…
- Trial name
- LEFFTDS (NCT02372773)
- Where
- 8 sites in United States, Canada
- Volunteers
- 398 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dementia With Lewy Bodies
RewinD-LB - Clinical Study of Neflamapimod in Patients With Dementia With Lewy Bodies
The purpose of this study is to determine whether neflamapimod can improve learning skills, problem solving skills, and memory loss in people diagnosed with DLB.
- Trial name
- NCT05869669
- Testing
- Neflamapimod
- Where
- 40 sites in United States, Netherlands and 1 more
- Volunteers
- 159 people
- Sponsor
- EIP Pharma Inc
Agitated; State, Acute Reaction to Stress
Does Low Flow Anesthesia Reduce Postanaesthetic Emergence Agitation?
In this study, the investigators aimed to compare postanesthetic agitation in patients undergoing laparotomic gynecological surgery under general anesthesia using sevoflurane at a fresh gas flow rate of 2 L / min with fresh gas…
- Trial name
- NCT03862391
- Testing
- Analgesics, Antiemetics
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Huntington Disease
Characterization and Quantification of Motor Speech Disorders in Huntington's Disease: Identification of Acoustic Markers
The study proposes to identify deviant speech dimensions in patients with HD at presymptomatic and declared stages of the disease, compared to healthy subjects, using the computerized MonPaGe speech protocol.
- Trial name
- TPMH (NCT04630574)
- Testing
- Speech evaluation with the clinical evaluation of dysarthria, complete assessment of the MonPaGe computerized protocol
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Bordeaux
Healthy Aging, Alzheimer Disease
Lactate for Energy and Neurocognition
Improved cardiorespiratory fitness following an aerobic exercise program elicits cognitive benefit in elderly subjects and memory improvement in Alzheimer's disease (AD).
- Trial name
- LEAN (NCT05207397)
- Testing
- Lactate infusion
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Kansas Medical Center
Alzheimer's Disease
Usability Study of Spaced Retrieval Exercise Using Mobile Devices for Alzheimer's Disease Rehabilitation
The focus of this work is to explore the use of modern mobile technology to enable people with Alzheimer's disease to improve their abilities to perform activities of daily living and hence to promote independence and…
- Trial name
- NCT02005380
- Testing
- Text-based task, Graphic-based Task
- Where
- Jordan
- Volunteers
- 20 people
- Sponsor
- German-Jordanian University
Alzheimer's Disease
Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease
The purpose of this study is to determine the safety and efficacy of TRx0237 in the treatment of subjects with mild to moderate Alzheimer's Disease.
- Trial name
- NCT01689246
- Testing
- TRx0237 150 mg/day, TRx0237 250 mg/day
- Where
- 121 sites in United States, Australia and 14 more
- Volunteers
- 891 people
- Sponsor
- TauRx Therapeutics Ltd
Dementia
Decreasing Agitation in Patients With Dementia Through the Use of Weighted Blankets
The purpose of this research study is to determine whether the use of weighted blankets help reduce behavioral and psychological symptoms, including agitation in people with dementia.
- Trial name
- NCT03643991
- Testing
- Weighted Blanket
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Alzheimer Disease
Satisfaction With Orodispersible vs Conventional Memantine in Moderate to Severe Alzheimer's Disease
The goal of this clinical study is to evaluate satisfaction with the use of orodispersible Memantine (OD) versus conventional Memantine tablets (MTb) using the validate SATMED-Q in patients with moderate to severe Alzheimer's…
- Trial name
- NCT07417670
- Testing
- Memantine, Memantine Oral Tablet
- Where
- 4 sites in Mexico
- Volunteers
- 105 people
- Sponsor
- Carnot Laboratories
Dementia, Caregivers
The Balance Study Balancing Life and Reducing Stress For Those Providing Elder Care
The primary goals of this exploratory/developmental (R21) study are to evaluate the feasibility and acceptability of a MBSR intervention for caregivers of patients with dementia, and to estimate the effectiveness of program…
- Conditions
- Dementia, Caregivers, Stress
- Trial name
- Balance (NCT00615082)
- Testing
- Mindfulness-Based Stress Reduction, Caregiver Education & Social Support
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Alzheimer's Disease, Hearing Loss
Auditory Rehabilitation and Cognition in Alzheimer Patients
Alzheimer disease is a neurodegenerative disease. Recent studies suggest that subjects with hearing loss are more likely to develop Alzheimer's disease.
- Trial name
- RACO-MA (NCT03002142)
- Testing
- Hearing aids
- Where
- France
- Volunteers
- 9 people
- Sponsor
- University Hospital, Tours
Dementia
Community Based Music and Dance Movement Therapy Group for Older Adults With Dementia
This study explores the value of a particular community based music and dance movement therapy group for older adults with dementia? To answer this question, the investigators intend to address the following two sub-questions: 1.
- Trial name
- NCT03404050
- Testing
- Music and dance movement therapy
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Edge Hill University
Dementia Alzheimers
Low Dose Ionizing Radiation Using CT Scans as a Potential Therapy for Alzheimer's Dementia: A Pilot Study
The goal of this project is to determine whether low doses of ionizing radiation (LDIR) from repeat CT scanning improves function, cognition and/or behavior in severe AD.
- Trial name
- LDIR-CT-AD (NCT03597360)
- Testing
- CT scan
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Baycrest
Alzheimer's Disease, Dementia
High Intensity Light Therapy in Alzheimer's Disease
The purpose of this study is to determine whether bright light improves the sleep, mood, and behavior of persons with Alzheimer's disease and related dementias (AD) who live in long-term care settings and, if so, to determine the…
- Trial name
- NCT00065689
- Testing
- high-intensity light therapy
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
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