Clinical trials: Dementia, completed
Dementia
"Living Together With Dementia"_Creation and Validation of a Training Program for Family Caregivers of People With Dementia to Live at Home
This study aims to experimentally evaluate the training program for family caregivers of people with dementia_"Living together with Dementia."
- Trial name
- NCT03015428
- Testing
- psychoeducation
- Where
- Portugal
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Leukemia
Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia
The purpose of this study was to determine the efficacy and safety of twice daily (bid) oral midostaurin in patients with Aggressive Systemic Mastocytosis (ASM) or Mast Cell Leukemia (MCL) with or without an Associated…
- Trial name
- NCT00782067
- Testing
- Midostaurin (PKC412)
- Where
- 29 sites in United States, Australia and 10 more
- Volunteers
- 116 people
- Sponsor
- Novartis Pharmaceuticals
Alzheimer's Disease, Safety
Assessment of Safety, Tolerability and Blood Concentrations of Single Doses of AZD3839 in Healthy Volunteers
The purpose of the study is to assess the safety, tolerability and blood concentration of AZD3839 following oral administration of single doses in healthy men and women of non-childbearing potential
- Conditions
- Alzheimer's Disease, Safety, Tolerability, Blood Concentration
- Trial name
- NCT01348737
- Testing
- AZD3839
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Parkinson Disease
A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment
This study will evaluate the safety, tolerability, and potential effects on cognition of GRF6021, a plasma-derived product, administered as an intravenous (IV) infusion, to subjects with Parkinson's disease and cognitive…
- Trial name
- NCT03713957
- Testing
- GRF6021
- Where
- 29 sites in United States, Australia and 1 more
- Volunteers
- 79 people
- Sponsor
- Alkahest, Inc.
Alzheimer's Disease
To Compare Positron Emission Tomography (PET) Measurements of Fibrillar Amyloid Burden
The purpose of this study is to compare PET measurements of fibrillar amyloid burden using [18F]AZD4694.
- Trial name
- NCT00991419
- Testing
- [18F]AZD4694
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Chorea, Huntington's Disease
Treatment of Huntington's Chorea With Amantadine
Huntington's disease is a chronic disorder passed on through genetic autosomal dominant inheritance. The condition usually begins between the ages of 30 and 50 years and it is characterized by involuntary movements in the face…
- Trial name
- NCT00001930
- Testing
- Amantadine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Agitation
Scalp Nerve Block on Emergence Agitation
Emergence agitation is a common problem in children during recovery from sevoflurane anesthesia. Pain is considered as a cause of postoperative emergence agitation and compounding factor of agitation assessment in children.
- Trial name
- NCT02428283
- Testing
- Ropivacaine, Remifentanil, Sevoflurane
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Ajou University School of Medicine
Alzheimer Disease
Effects of Dopaminergic Therapy in Patients With Alzheimer's Disease
This is phase IIa 24-week, prospective, randomized, double-blind placebo controlled study. The study is designed to evaluate the efficacy, safety, and tolerability of transdermal patch of Rotigotine (RTG) versus placebo (PLC) as…
- Trial name
- DOPAD (NCT03250741)
- Testing
- Rotigotine transdermal patch
- Where
- Italy
- Volunteers
- 94 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Alzheimer's Disease
Deep Transcranial Magnetic Stimulation for Treatment of Alzheimer's Disease
The primary objective of this trial is to assess the ability of Transcranial Magnetic Stimulation with H coil to prefrontal cortex , with an addition of cognitive brain training, to improve cognitive performance in patients with…
- Trial name
- NCT01179373
- Testing
- TMS, H coil
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- Brainsway
Alzheimer's Disease
Alzheimer's Disease Reminiscence Quality of Life
The effectiveness of reminiscence for dementia has been claimed as an effective tool, but scientific validation and systematic assessment of this method is needed.
- Trial name
- NCT01295957
- Testing
- reminiscence therapy, comparison group, control
- Where
- Argentina
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Rosario
Alzheimer's Disease
Long-term Safety and Tolerability of AFFITOPE AD01
The purpose of this study is to assess the long-term tolerability and -safety of AFFITOPE AD01 applied during AFFiRiS 001
- Trial name
- NCT00711139
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Affiris AG
Dementia
Efficacy of 1072nm Infrared Stimulation on Executive Functioning in Dementia
This study will employ a double-blind, placebo-controlled approach to assess the effect of 1072nm infrared (IR) phototherapy on the behavioral and cognitive symptoms associated with early and mid-stage dementia.
- Trial name
- NCT01059877
- Testing
- 1072nm infrared Photobiomodulation, Photobiomodulation SIMULATED
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Quietmind Foundation
Empathy, Attitude
Exploring the Effectiveness the Attitude, Competence of Care, Empathy Among the Home Care Workers With Dementia People
This study develop a new virtual reality course for home care workers to experience the view of dementia people with BPSD and the relative feelings.
- Conditions
- Empathy, Attitude, Competence
- Trial name
- NCT05541575
- Testing
- VR films
- Where
- Taiwan
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Alzheimer's Disease, Dementia
The INCREASE Study - Delaying the Onset of Alzheimer's Symptomatic Expression
The study will examine the impact on cognitive reserve of a pharmacist-physician patient-centered medication therapy management intervention to address inappropriate medication use as identified by the Beers 2015 list.
- Trial name
- INCREASE (NCT02849639)
- Testing
- Medication Therapy Management (MTM), Scopolamine patch
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Daniela Moga
Alzheimer Disease, Dementia
ADVANCE Study: Alzheimer Disease eVAluation iN Clinical PracticE
In 1906, Dr. Alois Alzheimer first described the disease that later took his name. Today, 100 years later, 24 million people worldwide suffer from Alzheimer's disease or other dementias.
- Conditions
- Alzheimer Disease, Dementia, Cognitive Disorders
- Trial name
- ADVANCE (NCT01772095)
- Where
- Greece
- Volunteers
- 389 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Agitation
Liquid Risperidone in the Treatment of Acute Agitation in Psychiatrically Hospitalized Children
The goal of this study is to demonstrate safety and efficacy of liquid risperidone in psychiatrically hospitalized children, ages 4-12, who would be put in seclusion or restraint, or given an intramuscular injection of…
- Trial name
- NCT00790075
- Testing
- risperidone
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stony Brook University
Alzheimer's Disease
A Clinical Study to Evaluate the Pharmacokinetics (PK) of Corplex™ Donepezil Transdermal Delivery System (TDS) Applied to Different Body Locations
A Phase 1, Crossover Study to Evaluate the Pharmacokinetics of Corplex™ Donepezil 10 mg Transdermal Delivery System Applied to Different Body Locations
- Trial name
- NCT03432195
- Testing
- Donepezil TDS
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Corium, Inc.
Pathologic Processes
Adapting Connect-Home Transitional Care for the Unique Needs of Persons With Alzheimer's Disease and Other Dementias and Their Caregivers
This primary purpose of this study will be to (1) examine the feasibility and acceptability of transitional care focusing on care needs of skilled nursing facility (SNF) patients with dementia and their caregivers (primary aim).
- Trial name
- NCT05887388
- Testing
- Connect-Home Plus
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of North Carolina, Chapel Hill
Myocardial Infarction, Ischemic Stroke
Emulation of the Moderate Alcohol and Cardiovascular Health Trial (MACH15)
The aim of this study is to assess how long-term alcohol consumption influences health risks by emulating the Moderate Alcohol and Cardiovascular Health Trial (MACH15).
- Conditions
- Myocardial Infarction, Ischemic Stroke, Angina Pectoris, Coronary Revascularization
- Trial name
- NCT06583161
- Testing
- Moderate drinking, Quitting, Social drinking
- Volunteers
- 503,325 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Post-stroke Dementia
Acupuncture Combined With Nimodipine for Prevention of Post-stroke Dementia
To observe the clinical efficacy of TCM acupuncture combined with western medicine nimodipine for prevention of post-stroke dementia by comparing with clinical conventional treatment methods.
- Trial name
- NCT06007573
- Testing
- The control group received oral nimodipine tablets
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Yuzhen Pan
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