Clinical trials: Dementia, completed
Subjective Memory Complaint
Lifestyle Remodeling in Subjective Memory Complaint (SMC): Brain Imaging and Blood Biochemistry Study
The specific study aims: 1. To investigate whether the brain function is affected by the past life experiences, such as lifestyle and physiology-related factors in SMC. 2.
- Trial name
- NCT04162990
- Testing
- Lifestyle remodeling Intervention, Does Comparator: regular treatment
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Mild Cognitive Impairment
Effect of IVIG on Cerebral and Retinal Amyloid in Mild Cognitive Impairment Due to Alzheimer Disease
This is a proof of concept study to determine if changes in brain amyloid levels are evident three months after infusion of 0.4 g/kg of IVIG every 14 days x 5 infusions.
- Trial name
- NCT03319810
- Testing
- Octagam 10%
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Sutter Health
Alzheimer Disease
Tau Screening Study in Patients With Early Symptomatic AD
This protocol is designed to serve as a pre-screening study for subjects who are potentially eligible for Alzheimer's Disease (AD) therapeutic trials that require tau imaging for inclusion by means of a flortaucipir F18 Positron…
- Trial name
- NCT03322462
- Testing
- Flortaucipir F18, Brain PET Scan
- Where
- 10 sites in United States, Canada
- Volunteers
- 155 people
- Sponsor
- Avid Radiopharmaceuticals
Dementia
Palliative Care at Home for Dementia
The proposed project is a randomized controlled trial of a new home-based palliative care program for adults with advanced dementia and their caregivers within the Mount Sinai Health System.
- Trial name
- NCT03798327
- Testing
- Home Palliative Care
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Alzheimer's Disease, Amnestic Mild Cognitive Impairment
[18F]MK-6240 Positron Emission Tomography (PET) Tracer First-in-Human Validation Study (MK-6240-001)
This 2-part, open-label study was designed to investigate the safety, tolerability, and efficacy of [18F]MK-6240, a Positron Emission Tomography (PET) imaging agent, for the quantification of neurofibrillary tangle (NFT)…
- Trial name
- NCT02562989
- Testing
- [18F]MK-6240, ~185 MBq, [18F]MK-6240, ~160 MBq
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Frontotemporal Lobar Degeneration
Effects of Tolcapone on Frontotemporal Dementia
This study will test the effects of a medication called tolcapone on cognitive, behavioral, and language problems seen in patients with frontotemporal dementia (FTD).
- Trial name
- NCT00604591
- Testing
- Tolcapone
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Columbia University
Alzheimer's Disease
Safety and Tolerability of Rivastigmine With Add-on Memantine in Patients With Probable Alzheimer's Disease
This is a prospective, 26-week, open-label, single-arm multi-center pilot study. Eligible patients will receive open-label treatment with rivastigmine capsules plus memantine tablets as add on therapy.
- Trial name
- NCT00305903
- Testing
- Rivastigmine, memantine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Novartis
Alzheimer Disease, Mild Cognitive Impairment
Feasibility and Effects of Valaciclovir Treatment in Persons With Early Alzheimer's Disease
This study investigates the effects of Valaciclovir treatment to individuals with Alzheimer's disease or Mild Cognitive Impairment of Alzheimer's Disease Type.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Herpes Simplex
- Trial name
- VALZ-Pilot (NCT02997982)
- Testing
- Valaciclovir 500Mg Tablet
- Where
- 2 sites in Sweden
- Volunteers
- 33 people
- Sponsor
- Hugo Lovheim
Alzheimer Disease
Caregiver Speaks: A Technologically Mediated Storytelling Intervention
Caregiver speaks is a randomized trial of a Photo elicitation intervention for caregivers of Alzheimers patients.
- Trial name
- NCT04103580
- Testing
- Photo elicitation
- Where
- United States
- Volunteers
- 457 people
- Sponsor
- Washington University School of Medicine
Alzheimer Disease
Drug-Drug Interaction Study With Rifampin
The purpose of the study is to determine if the concomitant administration of rifampin with BMS-708163 will affect the Pharmacokinetics of BMS-708163 and to assess safety and tolerability of co-administration BMS-708163 and…
- Trial name
- NCT01002079
- Testing
- BMS-708163, Rifampin
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Behavioral and Psychiatric Symptoms of Dementia, Alzheimer Disease
Group-Based Telehealth Music Therapy Intervention for Patients With Dementia: A Pilot Study
Twelve participants and their care partners will be randomized for the intervention. The music therapy intervention takes place once a week for 6 weeks via telemedicine, with the first session reserved for music therapy…
- Conditions
- Behavioral and Psychiatric Symptoms of Dementia, Alzheimer Disease, Lewy Body Disease, Frontotemporal Dementia
- Trial name
- NCT05508646
- Testing
- Music therapy intervention, Personalized music CD
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Geisinger Clinic
Alzheimer Disease, Amyotrophic Lateral Sclerosis
The Ontario Neurodegenerative Disease Research Initiative
The Ontario Neurodegenerative Disease Research Initiative (ONDRI) is a province-wide collaboration studying dementia and how to improve the diagnosis and treatment of neurodegenerative diseases including: Alzheimer's disease (AD)…
- Conditions
- Alzheimer Disease, Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Parkinson Disease
- Trial name
- ONDRI (NCT04104373)
- Testing
- Observational Cohort
- Where
- 12 sites in Canada
- Volunteers
- 522 people
- Sponsor
- Ontario Neurodegeneration Disease Research Initiative
Dementia
Dementia Pain Management Educational Program
This study aims to develop and test a scale for exploring hospital nurses' knowledge about dementia pain and dementia pain management.
- Trial name
- NCT04256382
- Testing
- dementia pain care education, dementia care education
- Where
- Taiwan
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Alzheimer's Disease, Dementia
Care Management for Patients With Alzheimer Disease and Their Family Caregivers
This is a clinical trial to test the effectiveness of current guideline for the care of older adults with Alzheimer's disease. The study focuses on the primary care setting using a nurse care manager to facilitate guideline-level…
- Trial name
- NCT00246896
- Testing
- care management
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Dementia
Targeted Interdisciplinary Model for Evaluation and Treatment of Neuropscyhiatric Symptoms
Almost all people who suffer from dementia experience neuropsychiatric symptoms (NPS) in the course of the disease. TIME (Targeted Interdisciplinary Model for Evaluation and treatment of neuropsychiatric symptoms) is a…
- Trial name
- TIME (NCT02655003)
- Testing
- TIME, Education-only intervention
- Where
- Norway
- Volunteers
- 229 people
- Sponsor
- Sykehuset Innlandet HF
Mild Cognitive Impairment
SYNchronizing Exercises, Remedies in Gait and Cognition at Home (SYNERGIC@Home)
Background: Prevention of Alzheimer's Disease and Related Dementias (ADRDs) may be possible for persons with subjective (SCI) or mild cognitive impairment (MCI), or normal cognition and risk factors.
- Trial name
- SYNERGIC@Hom (NCT04997681)
- Testing
- Combined Aerobic Exercise and Resistance Training (AE + RT), Cognitive Training (NeuropeakTM), Control Cognitive Training of Website Searching and Video Watching (WS+V)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of New Brunswick
Dementia, Hip Fractures
Care Delivery in Acute Hospital Settings: an Observational Study
This small observational study is a contractual component of a 5-year (2013-18) NIHR funded programme called PERFECTED (Peri-operative Enhanced Recovery hip FracturE Care of paTiEnts with Dementia) whose overall aim is to develop…
- Trial name
- PERFECTED (NCT02212353)
- Testing
- Observational study, not interventional
- Volunteers
- 180 people
- Sponsor
- University of East Anglia
Autism
Efficacy of Aripiprazole Versus Placebo in the Reduction of Aggressive and Aberrant Behavior in Autistic Children
Hypothesis: (1) Aripiprazole treatment will be superior to placebo in reducing aggression and irritability in autistic individuals as shown by reductions in the Aberrant Behavior Checklist-irritability subscale.
- Trial name
- Abilify (NCT00468130)
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Alzheimer Disease
Clinical Trial to Evaluate the Efficacy and Safety of GV1001 in Alzheimer Patients
This clinical study is designed as a multi-center, randomized, double-blind, placebo-controlled, parallel design, prospective, phase II clinical trial.
- Trial name
- NCT03184467
- Testing
- Normal Saline 0.9%, GV1001 0.56 mg, GV1001 1.12 mg
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- GemVax & Kael
Alzheimer Disease
Long Term Extension Study Evaluating Safety, Tolerability and Immunogenicity Of ACC-001 In Subjects With Mild To Moderate Alzheimer's Disease
The purpose of this study is to assess the long term safety, tolerability, and immunogenicity of ACC-001, an investigational active immunization product+, in subjects with mild to moderate Alzheimer's disease.
- Trial name
- NCT00955409
- Testing
- ACC-001(3µg) + QS21, ACC-001(10µg) + QS21, ACC-001(30µg) + QS21
- Where
- 17 sites in France, Germany and 1 more
- Volunteers
- 160 people
- Sponsor
- Pfizer
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.