Clinical trials: Dementia, completed
Alzheimer Disease, Parkinson Disease
Telephone Call From Acute Care Physicians to Long Term Care Physicians: Impact on Transitional Care of Elderly Patients
A telephone call from a physician taking care of a patient in the hospital to a physician in the long term care setting at the time of discharge can improve transitional care for elderly patients.
- Conditions
- Alzheimer Disease, Parkinson Disease, Dysphagia
- Trial name
- NCT00281749
- Testing
- TELEPHONE CALL
- Where
- 2 sites in United States
- Sponsor
- Maimonides Medical Center
Alzheimer Disease, Dementia
Triggered Palliative Care for Advanced Dementia
The objective of this study is to generate preliminary data for a large multi-site randomized clinical trial of a model of palliative care consultation for patients with advanced dementia, and for their family caregivers.
- Trial name
- NCT02719938
- Testing
- Specialty Palliative Care
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of North Carolina, Chapel Hill
Care-resistant Behavior, Dementia
Reducing Care-Resistant Behaviors During Oral Hygiene in Persons With Dementia
The main purpose of this study is to test a method of providing mouth care to persons with dementia who live in nursing homes. The method of providing mouth care is designed to reduce fear in persons with dementia, so that these…
- Trial name
- NCT01363258
- Testing
- Care-resistant mouth care (MOUTh), Evidence-based mouth care
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Accidental Falls
Effects of Tai-chi Programme on Mobility of People With Dementia
This study evaluates the feasibility and the preliminary effects of a simplified 10-step Tai-chi programme (a dyadic approach) on the mobility performance of people with mild to moderate dementia.
- Trial name
- NCT03341091
- Testing
- Tai-chi group
- Where
- 2 sites in Hong Kong
- Volunteers
- 26 people
- Sponsor
- The Hong Kong Polytechnic University
Delirium, Cognitive Impairment
Effects of a Dementia-friendly Program
Frail older persons with cognitive impairment are at special risk of experiencing delirium during acute hospitalisation. The purpose of this study was to investigate whether a dementia-friendly hospital program contributes to…
- Conditions
- Delirium, Cognitive Impairment, Dementia
- Trial name
- NCT04737733
- Testing
- The dementia friendly program
- Where
- Norway
- Volunteers
- 423 people
- Sponsor
- University Hospital, Akershus
Alzheimer Disease
A Study of Healthy Subjects to Assess the Effect of LY450139 on Amyloid Beta Peptide Production Rate and or Dose Response.
To test that LY450139, a gamma-secretase inhibitor, will reduce the rate of newly synthesize Amyloid Beta by determining the amount of newly synthesized 13C6 leucine-labeled Amyloid Beta in lumbar cerebrospinal fluid from…
- Trial name
- NCT00765115
- Testing
- LY450139
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Mild Cognitive Impairment, So Stated, Mild Dementia
Cognitive/Physical Computer-Game Blended Training of Elderly: Neuroscientific LLM Studies
The study involved Information and Communication Technologies (ICT) and more specifically computer exercises blended with game activities.
- Conditions
- Mild Cognitive Impairment, So Stated, Mild Dementia, Healthy
- Trial name
- LLM-AUTH (NCT02313935)
- Testing
- LLM, FFA, Brain Fitness
- Volunteers
- 581 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Dementia
Deprescribing Intervention Among Nursing Home Residents With Major Neurocognitive Disorders
Canadians with neurocognitive disorders often are admitted to nursing homes when their disease reaches an advanced stage. At the end of their life, they may encounter adverse symptoms related to medications they no longer need…
- Trial name
- OptimaMedLTC (NCT05155748)
- Testing
- Continuous education and knowledge exchange
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Dre Edeltraut Kröger
Alzheimer Disease, H Pylori Infection
The Improvement of Black Raspberry in Obese and Mild AZ Patients Infected With H. Pylori
The current study was designed to check the impact of black raspberry (BR) on obese and mild Alzheimers (AZ) patients infected with Helicobacter pylori (H pylori).
- Trial name
- BR (NCT05680532)
- Testing
- Black raspberry
- Where
- Taiwan
- Volunteers
- 21 people
- Sponsor
- Chung Shan Medical University
Alzheimer Disease, At Risk, Alzheimer Disease, Protection Against
The STEP 4Life Trial
The objective of this study is to test the feasibility of using behavioral economic interventions (gamification with social incentives) targeting daily step counts to prevent or delay the development of Alzheimer's Disease and…
- Conditions
- Alzheimer Disease, At Risk, Alzheimer Disease, Protection Against, Dementia
- Trial name
- NCT05069155
- Testing
- Gamification
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Pennsylvania
Alzheimer's Disease
Effect of Exercises Training in Patients With Mild Cognitive Impairment and Early Alzheimer's Disease
Recent studies have shown that aerobic exercises and dual-task training are effective in improving overall cognitive function in patients with cognitive impairment or dementia.
- Trial name
- NCT02074215
- Testing
- Aerobic exercises, Stretch exercise
- Where
- Taiwan
- Volunteers
- 19 people
- Sponsor
- National Taiwan University Hospital
Alzheimer Disease
GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease
This is a randomized, double-blind, placebo-controlled study that assessed the efficacy, safety, and tolerability of 2 dose levels of COR388 in subjects with a clinical diagnosis of mild to moderate Alzheimer's disease (AD)…
- Trial name
- NCT03823404
- Testing
- COR388 capsule
- Where
- 93 sites in United States, France and 4 more
- Volunteers
- 643 people
- Sponsor
- Cortexyme Inc.
Alzheimer Disease
Olfactory Neuroepithelial Tissue of Alzheimer Disease
The purpose of this study is to evaluate the olfactory neuroepithelium as a biomarker of Alzheimer disease. The early diagnosis of Alzheimer disease is of importance for obtaining better response to treatment, but recently…
- Trial name
- NCT02129452
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Gait Disorders, Neurologic, Parkinson Disease
Gamma Sensory Flicker for Parkinson's Disease Patients With Freezing of Gait
This study aims to answer the question: to assess the safety, and tolerability of gamma light in Parkinson's disease (PD) patients with freezing of gait (FOG).
- Trial name
- Flicker w FOG (NCT06295458)
- Testing
- David Delight Plus Device
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Anxiety, Caregiver Burden
Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With ADRD
The purpose of the study is to test if Acceptance and Commitment Therapy (ACT), a behavioral intervention designed to increase psychological flexibility in the face of challenges, reduces anxiety associated psychological distress…
- Trial name
- (TACTICs) (NCT04780178)
- Testing
- Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults with Alzheimer's Disease and Related Dementias
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Alzheimer's Disease, Blood Biomarkers
Blood Biomarkers for Screening of Alzheimer's Disease
The goal of this observational study is to estimate the screen performance of blood biomarkers of interest (Aβ40 and Aβ42, P-Tau181, P-Tau217, GFAP and NfL) in patients with Alzheimer's disease (AD), mild cognitive impairment due…
- Trial name
- NCT06477484
- Testing
- Blood biomarker
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Parkinson's Disease, Sleep Disordered Breathing
Cognitive Benefits of Treating Sleep Apnea in Parkinson's Disease
Patients with sleep disordered breathing (SDB), also called sleep apnea, experience nighttime disrupted sleep and, because they stop breathing for short periods during the night, do not get sufficient oxygen to their brains.
- Trial name
- TAP (NCT00492115)
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of California, San Diego
Dementia, Oral Health Care
The Effect of Oral Health Care Program on Oral Hygiene and Oral Function for the Elderly Patient With Dementia in Day Care Center
This study evaluated the effects of an oral health care program on oral hygiene and oral function in older adults with dementia attending a day care center.
- Conditions
- Dementia, Oral Health Care, Oral Hygiene
- Trial name
- NCT07401693
- Testing
- Oral Health Care Program
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- Shiou-fang Lu
Alzheimer Disease
Virtual Reality Cognitive Therapy for Alzheimer's Disease
To evaluate the usability, feasibility, and acceptability of VRCT iteratively on 36 AD/ADRD individuals with mild to moderate CI.
- Trial name
- VRCT (NCT05788848)
- Testing
- VRCT
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Claritytek, Inc.
Alzheimer's Disease (AD), Alzheimer's Disease (AD) Related Disorders
MEMENTO-VAScular COmponents of Dementia
A Multicenter national longitudinal cohort study including at least 800 individuals recruited from French Research Memory Centers and followed up over 36 months and included in Memento.
- Trial name
- VASCOD (NCT02264899)
- Testing
- in Memento-VASCOD
- Where
- 10 sites in France
- Volunteers
- 332 people
- Sponsor
- University Hospital, Bordeaux
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