Clinical trials: Demodex Blepharitis
Demodex Blepharitis
Impact of XDEMVY® on Demodex Blepharitis in Soft Contact Lens Wearers
To compare the efficacy of XDEMVY ophthalmic drop to its vehicle control for the treatment of Demodex blepharitis and its impact on the soft contact lens wearing experience.
- Trial name
- Ariel (NCT06182358)
- Testing
- Lotilaner ophthalmic solution, 0.25%, Vehicle control
- Where
- 14 sites in United States
- Volunteers
- 145 people
- Sponsor
- Tarsus Pharmaceuticals, Inc.
Meibomian Gland Dysfunction, Demodex Infestation of Eyelid
Effect of an Exploratory Vehicle on Meibomian Gland Dysfunction in Patients With Demodex
The purpose of this study is to evaluate and compare the effect of two dosing regimens, BID versus TID dosing, of an Exploratory Vehicle (EV) on meibomian gland dysfunction (MGD) in patients with Demodex lid infestation.
- Conditions
- Meibomian Gland Dysfunction, Demodex Infestation of Eyelid, Blepharitis, Demodectic Blepharitis
- Trial name
- Rhea (NCT06054217)
- Testing
- Vehicle of TP-03
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tarsus Pharmaceuticals, Inc.
Blepharitis
Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis
The purpose of this study is to compare the safety and efficacy of TP-03, 0.25%, an eyedrop, to its vehicle control for the treatment of blepharitis due to Demodex, a microscopic mite frequently found in human hair follicles.
- Trial name
- Saturn-1 (NCT04475432)
- Testing
- TP-03, 0.25%, TP-03 Vehicle
- Where
- 15 sites in United States
- Volunteers
- 421 people
- Sponsor
- Tarsus Pharmaceuticals, Inc.
Blepharitis
Trial to Evaluate the Efficacy and Safety of TP-03, LIBRA Study
The Phase III main study is a randomized, controlled, multicenter, double blind, trial to evaluate the efficacy and safety of TP-03 (lotilaner ophthalmic solution, 0.25%), for the treatment of Demodex blepharitis in Chinese…
- Trial name
- NCT05629390
- Testing
- Lotilaner, Vehicle Control
- Where
- 21 sites in China
- Volunteers
- 163 people
- Sponsor
- LianBio LLC
Chronic Blepharitis
Demodex Blepharitis Treatment Study
This is a randomized clinical trial to determine the safety and efficacy of terpinen-4-ol (T4O), the most active ingredient of tea tree oil (TTO), in eradicating ocular demodicosis (reducing ocular demodex counts and achieving…
- Trial name
- DBTS (NCT01647217)
- Testing
- Terpinen-4-ol
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- BioTissue Holdings, Inc
Blepharitis
Study of the Safety and Efficacy of Moxidectin Tablets for the Reduction of Demodex Eyelash Infestation
A Single-Center, Investigator-Masked, Randomized, Placebo-Controlled, Investigator Initiated Study of the Safety and Efficacy of Moxidectin Tablets for the Reduction of Demodex Eyelash Infestation
- Trial name
- NCT06795165
- Testing
- Moxidectin 2 MG Oral Tablet
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Eye Research Foundation, Inc.
Demodex Blepharitis
Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis
This is a randomized, double-masked, placebo-controlled, dose-ranging, parallel-group, multi-center study designed to evaluate the safety and efficacy of GLK-321 in patients with Demodex blepharitis.
- Trial name
- NCT07400965
- Testing
- GLK-321 low dose BID, GLK-321 mid dose BID, GLK-321 high dose BID
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Glaukos Corporation
Meibomian Gland Dysfunction, Blepharitis
Pilot Study Comparing the Safety and Efficacy of Two Dosing Regimens of TP-03 for the Treatment of MGD
The purpose of this study is to compare the safety and efficacy of TP-03, 0.25%, an eyedrop, BID vs TID dosing regimens for the treatment of meibomian gland dysfunction in patients with Demodex lid infestation.
- Conditions
- Meibomian Gland Dysfunction, Blepharitis, Demodex Infestation
- Trial name
- Ersa (NCT05454956)
- Testing
- TP-03, TP-03 Vehicle
- Where
- 5 sites in United States
- Volunteers
- 39 people
- Sponsor
- Tarsus Pharmaceuticals, Inc.
Demodex Blepharitis
Efficacy and Tolerability of Blephademodex Wipes
Primary Objective To evaluate efficacy of Blephademodex eyelid hygiene wipe treatment with a subsequent maintenance period with Blephaclean lid cleansing wipes in Demodex blepharitis, as assessed by the change in ocular symptoms…
- Trial name
- NCT04780165
- Testing
- Blephademodex
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Laboratoires Thea
Blepharitis
Trial to Evaluate the Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis
The purpose of this study is to compare the safety and efficacy of TP-03, an eyedrop, to its vehicle control for the treatment of blepharitis due to Demodex, a microscopic mite frequently found in human hair follicles.
- Trial name
- Saturn-2 (NCT04784091)
- Testing
- TP-03, TP-03 Vehicle
- Where
- 21 sites in United States
- Volunteers
- 412 people
- Sponsor
- Tarsus Pharmaceuticals, Inc.