Clinical trials: Demonstrate Effectiveness of Virtual Simulator in Improving or Performance
Healthy Subjects, Rheumatoid Arthritis
Biodistribution, Dosimetry and Performance of [68Ga]Ga-DOTA-Siglec-9 in Healthy and Patients With Rheumatoid Arthritis, Vasculitis or Pulmonary Sarcoidosis
This study evaluates safety, tolerability, biodistribution and performance of the [68Ga]Ga-DOTA-Siglec-9 following a single intravenous administration in patients with active rheumatoid arthritis, vasculitis or pulmonary…
- Conditions
- Healthy Subjects, Rheumatoid Arthritis, Vasculitis, Pulmonary Sarcoidosis
- Trial name
- SIGLEC (NCT03755245)
- Testing
- [68Ga]Ga-DOTA-Siglec-9
- Where
- Finland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Sleep Initiation and Maintenance Disorders, Mental Disorders
A Study to Assess the Effect of Single and Multiple Doses Org 50081 and a Single Dose of Zopiclone on Next-day Driving Ability and Psychomotor Performance in Healthy Volunteers. (P05794) (COMPLETED)
This trial is to investigate the effect on next-day driving performance and psychomotor performance in healthy volunteers.
- Trial name
- NCT00798395
- Testing
- Org 50081, zopiclone
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
High Myopia, Cataract
Visual Performance of Functional Intraocular Lenses in Cataracts
This is a prospective, multi-center, randomized comparative study. The purpose of the study is to evaluate and compare the postoperative visual outcomes and quality of vision of two diffractive trifocal intraocular lenses (IOLs)…
- Trial name
- NCT05581888
- Testing
- trifocal intraocular lens
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Eye & ENT Hospital of Fudan University
NSCLC Stage IV, NSCLC Stage IIIB
1st Line Durvalumab in PS 2 NSCLC Patients
The aim of the trial is to assess efficacy and safety of the treatment with durvalumab in PS 2 patients with treatment-naïve, locally advanced or metastatic, PD-L1 positive NSCLC who are considered unsuitable for combination…
- Trial name
- NCT03620669
- Testing
- Durvalumab
- Where
- 11 sites in Switzerland
- Volunteers
- 48 people
- Sponsor
- Swiss Cancer Institute
Type2 Diabetes, Physical Activity
Which Exercises Should Diabetic Patients do?
Type 2 Diabetes Mellitus (DM) is a widespread worldwide disease. Exercise therapy is an effective method but which exercise types are more effective is an important question.
- Trial name
- NCT03475069
- Testing
- Custom Designed Exercises, Plates Exercises, Calisthenics Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Biruni University
Anxiety, Well-Being (Psychological Flourishing)
How Can We Help? Wellbeing Interventions for Choral Music Ensembles
The goal of this clinical trial is to learn if psychology and music based interventions can impact anxiety and overall wellbeing in adolescents enrolled in choral music classes.
- Conditions
- Anxiety, Well-Being (Psychological Flourishing), Performance Anxiety
- Trial name
- NCT07298031
- Testing
- Box breathing, Magnify, Emotion regulation through choral literature
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jess Walls
Diagnostic Imaging, Common Systemic Diseases
Prospective User Study and Clinical Validation of Multimodal Medical Imaging Large Models
Following model development and locking, the fixed model is evaluated in prospectively collected CT cohorts from a single center. The study is observational and does not affect clinical care.
- Conditions
- Diagnostic Imaging, Common Systemic Diseases, Artificial Intelligence (AI)
- Trial name
- NCT07555002
- Testing
- Standalone Radiologist Interpretation, AI-assisted Radiologist Interpretation
- Where
- China
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Southern Medical University
Anyone Who Meets the Eligibility Criteria Can Use the Software
Validation of the Performance of the COBOX Solution for Measuring Heart Rate and Respiratory Rate
Quantiq.io "COBOX" is a software as a medical device. It relies on remote photoplethysmography, allowing for the remote measurement of a patient's physiological parameters from a healthcare professional's or patient's device…
- Trial name
- COBOX (NCT05528042)
- Testing
- Heart rate and respiratory rate measurement
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Quantiq.io
Vascular Access Complications
Comparison of AccuCath IV Catheter and Conventional IV Catheter in Interventional Radiology
The study will test a hypothesis that the AccuCath™ System will have a higher rate of successful first attempt peripheral IV placement and higher clinician and patient satisfaction compared to Conventional IV Catheters.
- Trial name
- NCT01940354
- Testing
- AccuCath IV Catheter System, Conventional IV Catheter System
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Sports Physical Therapy, Neuromuscular Subluxation of Joint
The Effect of Lumbar and Sacroiliac Manipulation on Football Players
The purpose of this study was to assess the immediate effects of chiropractic spinal manipulation methods on the lumbar and sacroiliac regions on professional soccer players' flexibility and leaping abilities.
- Trial name
- ELSMFP (NCT06568666)
- Testing
- Lumbar spinal manipulation, Sacroiliac joint manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- SEFA HAKTAN HATIK
Cataract, Refractive Lens Exchange
Visual Performance of Patients Implanted With a Multifocal IOL
The goal of this clinical trial is to learn about the visual performance of a new multifocal intra-ocular lens in patients presenting for cataract or refractive lens exchange surgery.
- Trial name
- VISUAL (NCT06111222)
- Testing
- AT ELANA
- Where
- 3 sites in Germany, Spain
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Elderly
Effects of Training in a Virtual Environment in Healthy Elderly
The objective of this work was to compare the effects of two balance training programs, one Nintendo Wii Fit-based and the other traditionally-based without the use of a gaming system, on the (1) balance, (2) gait, (3)…
- Trial name
- NCT01741402
- Testing
- Virtual Reality Training, Physical Therapy
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Safety and Effectiveness of the Siello S Lead
Safety and Performance Study of the Siello S Pacing Lead
The objective of the SIELLO study is to demonstrate the safety and effectiveness of the BIOTRONIK Siello S pacing lead.
- Trial name
- SIELLO (NCT01791127)
- Testing
- market-released BIOTRONIK pacemaker system including one or two Siello S leads.
- Where
- 53 sites in United States
- Volunteers
- 1,758 people
- Sponsor
- Biotronik, Inc.
Lung Cancer, Breast Cancer
Clinical Validation of AI-Assisted Radiotherapy Contouring Software for Thoracic Organs at Risk
The goal of this clinical trial is to evaluate performance and clinical applicability of AI-assisted radiotherapy contouring software (iCurveE) for thoracic organs at risk.
- Conditions
- Lung Cancer, Breast Cancer, Esophageal Cancer
- Trial name
- NCT05787522
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Venous Leg Ulcer
HM242-Gel vs Comparator
The primary objective of the study is to demonstrate that the HM242-Gel performs at least comparably to INTRASITE Gel with regard to wound healing.
- Trial name
- NCT04902651
- Testing
- HM242-Gel, Intrasite Gel
- Where
- 3 sites in Czechia, Slovakia
- Volunteers
- 73 people
- Sponsor
- B. Braun Ltd. Centre of Excellence Infection Control
Early Gastric Cancer, Gastric Adenoma
Performance of Endoscopic Submucosal Dissection According to the Sedation Method
Although proper sedation is mandatory for endoscopic procedures such as endoscopic submucosal dissection, the effects of sedation on ESD performance and complications have not been fully evaluated.
- Trial name
- NCT01806753
- Testing
- Intermittent midazolam/propofol injection controlled by endoscopist, Continuous propofol infusion with opioid administration
- Where
- South Korea
- Volunteers
- 157 people
- Sponsor
- Yonsei University
Cognitive Change
Oxygen as a Limiting Factor for Performing Multitasking
The aim of the present study was to evaluate whether hyperbaric oxygen (HBO) environment, with increased oxygen supply to the brain, will enable better performance of complex and/or multiple activities.
- Trial name
- NCT03126669
- Testing
- Hyperbaric oxygen, Hyperbaric chamber, normal air
- Where
- Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Low Back Pain
Evaluation of the Japet.W+ Medical Device for Low Back Pain Management
The JAPET.W+ medical device is a new dynamic distraction support system. It could be considered as a new solution in the therapeutic arsenal for managing common low back pain.
- Trial name
- EXODOMICILE (NCT07195422)
- Testing
- Japet.W+, Control (Standard treatment)
- Where
- 2 sites in France
- Volunteers
- 102 people
- Sponsor
- Japet Medical Devices
Coronary Artery Disease
Ultra-low-dose CACS in a Large Population
Radiation exposure to patients from CT for CAC scoring has steadily decreased in recent years. This is mainly achieved through lowering tube currents alongside with the introduction of iterative reconstruction algorithms which…
- Trial name
- ULDCACSLARGE (NCT03637231)
- Testing
- Ultra low-dose CTAC
- Where
- Switzerland
- Volunteers
- 301 people
- Sponsor
- University of Zurich
Flanks Fat Reduction vs. Control
Fat Reduction in the Flanks Area vs. Control
Prospective, blinded, one arm, baseline-controlled clinical study for the evaluation the performance of the UltraShape treatment for non-invasive fat reduction by compare control and treated flanks.
- Trial name
- NCT02465775
- Testing
- UltraShape treatment
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
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