Clinical trials: Dental Analgesia
Pain, Acute
Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients
The purpose of this study is to evaluate the analgesic effects of cannabidiol for patients who have undergone simple tooth extraction.
- Trial name
- SWAP (NCT04271917)
- Testing
- cannabidiol, acetaminophen 500mg and ibuprofen 200mg combo
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Tennessee
Dental Anxiety, Postoperative Pain
Effect of Alpha-Band Binaural Beats on Stress and Recovery in Third Molar Surgery
Preoperative anxiety and loud equipment noises, such as dental drills, create significant stress and autonomic fluctuations in patients undergoing oral surgery.
- Conditions
- Dental Anxiety, Postoperative Pain, Impacted Tooth, Binaural Beats
- Trial name
- NCT07881640
- Testing
- 10 Hz Alpha-Band Binaural Beats Track, Active Noise Cancellation (ANC)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alperen Kalyoncu
Complex Regional Pain Syndrome Type I, Complex Regional Pain Syndrome Type II
Neurotropin to Treat Chronic Neuropathic Pain
This study will examine the effectiveness of the drug neurotropin in treating chronic pain after injury to a limb or a large nerve.
- Trial name
- NCT00006289
- Testing
- Neurotropin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- National Institute of Nursing Research (NINR)
Dental Caries in Children, Wound Heal
Biostimulation After Tooth Extraction
This study evaluated the effect of low-level laser therapy on postoperative pain and wound healing in children undergoing primary molar extractions 40children, 6-10 years of age, systemically healthy, and had atraumatic…
- Trial name
- NCT06018584
- Testing
- Tooth extraction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hazal Özer
Breastfeeding
Dental Support Device During Breastfeeding as a Mean for Pain Control
Leboride is a dental support device that was developed for reducing pain during active labor. It is made of an inert material, placed in the woman's mouth and does not disturb breathing, talking, or any other activity expected…
- Trial name
- NCT02399774
- Testing
- Leboride
- Where
- Israel
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Yariv yogev
Hypersensitivity Dentin
Potassium Nitrate Gel and Diode Laser for Dentinal Hypersensitivity
The goal of this randomized clinical trial is to evaluate whether combining a potassium nitrate gel with diode laser therapy is more effective in treating dentinal hypersensitivity compared to using the gel alone.
- Trial name
- NCT06746558
- Testing
- Potassium Nitrate Gel and Diode Laser Therapy, Potassium Nitrate Gel Alone
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- University of Modena and Reggio Emilia
Dental Fear, Anesthesia, Local
Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children
Dental Fear and Anxiety (DFA) are at higher levels among children and often leads to avoidance of dental treatment. Negative experiences in the early years such as experience of pain during injections, fillings, or extractions…
- Conditions
- Dental Fear, Anesthesia, Local, Pediatric Dentistry
- Trial name
- NCT03779659
- Testing
- Synapse TENS device, Topical anesthetic gel
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston University
Post-op Pain
Study to Assess Dopamine Receptor Modulation With Rotigotine to Enhance Morphine Analgesia in the Dental Model
Narcotics are widely used as the mainstay of pain treatment, although increasing doses are required over time as the individual becomes tolerant to their effects.
- Trial name
- NCT02123979
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Pediatric Dentistry
Virtual Reality vs Nitrous Oxide in Pediatric Dentistry
Two groups of pediatric patients between the ages of 4 to 12 years old will be examined in this study. Control group will receive the standard of care dental treatment with under nitrous sedation (N2O) and will have a second…
- Trial name
- NCT05890898
- Testing
- Virtual Reality Headset, Nitrous Oxide
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Geisinger Clinic
Dental Anxiety, Hemodynamic
Anxiety and Hemodynamic Changes in Third Molar Extraction After Patient Education
This randomized clinical trial investigates the effect of different preoperative patient information strategies on anxiety levels and hemodynamic responses during third molar extraction.
- Conditions
- Dental Anxiety, Hemodynamic, Molar, Third, Tooth Extraction
- Trial name
- NCT07018115
- Testing
- Basic Preoperative Information, Detailed Verbal Preoperative Information, Visual Preoperative Information (2D Animation)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Ummugulsum Coskun
Pulpitis, Pain Management
The Effects of Three Oral Medications on Post-operative Pain Following Endodontic Treatment
Aim: eliminating or reducing pain following endodontic treatment is of great importance. The aim of this study is to compare the effects of Tramadol, Novafen and Naproxen on post-operative pain following instrumentation of root…
- Trial name
- NCT01178203
- Testing
- Tramadol, Novafen, Naproxen
- Sponsor
- Azad University of Medical Sciences
Pain, Postoperative, Endodontically Treated Teeth
Post-Endodontic Instrumentation Pain After in a Single Session Associated With Photobiomodulation
The objective of this double-blind, randomized controlled clinical study will be to evaluate the effect f PBM on pain after endodontic instrumentation in the single-session treatment of upper molars and premolars.
- Trial name
- NCT06253767
- Testing
- Endodontic Treatment, Low Level Laser Therapy, Simulation Low Level Laser therapy
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Pain
Study Comparing the Efficacy of Two Ibuprofen Formulations
This is a study of healthy volunteers to compare how quickly different ibuprofen products relieve dental pain.
- Trial name
- NCT00740857
- Testing
- ibuprofen Formulation 1, ibuprofen Formulation 2
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Effectiveness of Anesthesia Using Electronic Syringe in Children in the Context of Endotopy Treatment
Effectiveness of Intraligament vs IANB Anesthesia in Children Using Electronic Syringe
This randomized clinical study aims to evaluate the efficacy and pain response of two local anesthesia techniques in pediatric dental treatment using an electronic syringe: ligament anesthesia and inferior alveolar nerve block…
- Trial name
- NCT07095946
- Testing
- Electronic Syringe Intraligament Technique, Electronic syringe IANB Technique
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Latakia University
Dental Anxiety, Dental Pain
Nonpharmacologic Reduction of Periprocedural Distress and Drug Use
Objectives of this Phase I pilot trial are to provide data towards assessing and facilitating feasibility of a larger scale Phase II trial in which the effects of a calmative Comfort Talk® app can be unequivocally evaluated.
- Conditions
- Dental Anxiety, Dental Pain, Drug Use, Opioid Use
- Trial name
- NCT03328208
- Testing
- Comfort Talk® app, White Noise app
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Hypnalgesics, LLC
Postoperative Pain
Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial
This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery.
- Trial name
- NCT07413055
- Testing
- Dexamethasone 4 Mg/mL Injectable Solution, Dexamethasone 8Mg Solution for Injection
- Where
- Oman
- Volunteers
- 138 people
- Sponsor
- Oman Ministry of Health
Adverse Anesthesia Outcome
Preemptive Analgesia Using Intravenous Paracetamol
Dental treatment for children should be done in a calm atmosphere and without pain. Oral Propacetamol has been shown to be effective in a variety of postsurgical pain models.
- Trial name
- NCT02884921
- Testing
- Paracetamol
- Volunteers
- 87 people
- Sponsor
- Bnai Zion Medical Center
Reversible Pulpitis, Ibuprofen
Pain Management in Teeth With Reversible Pulpitis
Effective intraoperative pain management is vital in paediatric dentistry, especially during vital pulp therapy (VPT) for reversible pulpitis.
- Trial name
- NCT07114198
- Testing
- Ibuprofen 10 mg/kg
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Inonu University
Post-Dental Gingival Pain, Gingival Swelling
Efficacy and Safety of HA35 Gel for Post-Dental Gingival Pain and Swelling
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of 10% high-concentration 35 kDa hyaluronan (HA35) gel delivered via gel-soaked cotton balls in patients with gingival pain…
- Conditions
- Post-Dental Gingival Pain, Gingival Swelling, Postoperative Oral Pain, Dental Procedure-Related Discomfort
- Trial name
- HA35 (NCT07584655)
- Testing
- 10% High-Concentration 35 kDa Hyaluronan (HA35) Oral Topical Gel
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nakhia Impex LLC
Pain
Pain Management Following Dental Treatment Under General Anesthesia
The main goal of this study is to test the efficacy of postoperative pain management for cases undergoing extractions of primary teeth under GA using a validated measure.
- Trial name
- NCT06574516
- Testing
- Ibuprofen 200 mg, paracetamol
- Where
- Jordan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital