Clinical trials: Dental Analgesia
Tooth Pain
Cohort Comparison of Dental Nerve Block With Other Forms of Analgesia in Alleviating the Pain of Toothache
Toothache is a common source of pain for Emergency Department patients. There are several common ways to control the pain of toothache. But we do not know if any one of them is more effective than another.
- Trial name
- Cohort Dental (NCT01268436)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Albany Medical College
Dental Pain, Sensation Disorders
Meloxicam Versus Ibuprofen for Pain Control After Third Molar Exodontia in Adult Patients
Third molar extraction is a common dental procedure, offently related with pain and swelling. The purpose of this study is to evaluate if Meloxicam has a better effect relieving pain after the extraction than Ibuprofen, one of…
- Trial name
- NCT06704113
- Testing
- meloxicam 7,5mg
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Pulpitis
Submucosal Cryotherapy and Anti-inflammatory Drugs for Postoperative Pain Following Root Canal Treatment in Maxillary Molars
Pain after root canal treatment is a common problem, particularly in teeth with symptomatic irreversible pulpitis, a condition involving severe inflammation of the tissue inside the tooth.
- Trial name
- NCT07919938
- Testing
- Articaine Hydrochloride With Epinephrine, Submucosal Cryotherapy, Diclofenac Sodium
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Suez Canal University
Injection Pain, Local Anesthesia
Efficacy of Virtual Reality in Reducing Injection Pain and Anxiety During Local Anesthesia in Children
The aim of this study is to determine the efficacy of a virtual reality (VR) device in reducing injection pain and anxiety associated with local anesthesia in pediatric dental patients.
- Trial name
- NCT03772483
- Testing
- Local anesthesia with conventional syringe, Local anesthesia with conventional syringe + VR device
- Where
- Bulgaria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Anxiety, Odontophobia
Pain and Placebo Analgesia. Does Extended Information About Dental Procedures Reduce Pain Induced by Dental Treatment?
Information about the effectiveness of treatment has been found to reduce pain, termed placebo analgesia. In this study it will be investigated whether this finding translates to the dental clinic.
- Trial name
- NCT02160028
- Testing
- anesthetics and extended information before dental treatment, anesthetics and standard information before dental treatment
- Where
- Norway
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Analgesia
A Comparison of Analgesic Efficacy Between a Single Dose of ORG 28611, Morphine, and Placebo After Dental Impaction Surgery (Study P05800)
Patients will receive a single intravenous (IV) infusion administered over 3 minutes of either ORG 28611 (SCH 900111), 0.12 mg/kg morphine sulphate, or placebo, within 6 hours after dental surgery, when they experience moderate…
- Trial name
- NCT00782951
- Testing
- Org 28611, morphine sulfate
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Dental Anxiety, Pain Management
Effectiveness of Virtual Reality Technique on Children
Studying the effect of using virtual reality technique in managing pain, anxiety, and vital signs among pediatric dental patients.
- Conditions
- Dental Anxiety, Pain Management, Pediatric Dentistry
- Trial name
- NCT07722221
- Testing
- Conventional, Virtual reality
- Where
- Syria
- Volunteers
- 64 people
- Sponsor
- Latakia University
Third Molar Extraction
Analgesic Effect of Peripheral Dexmedetomidine
Dexmedetomidine is an alpha 2-adrenoreceptor agonist, which provides sedation, analgesia and anxiolysis in clinical practice (Cortinez et al., 2004,Hall et al., 2000).
- Trial name
- NCT00971178
- Testing
- local dexmedetomidine, Peripheral normal saline, IV dexmedetomidine
- Volunteers
- 105 people
- Sponsor
- The University of Hong Kong
Acute Pain
Preventive Treatment of Pain After Dental Implant Surgery
The objective of this prospective randomized double-blind study was to evaluate the effects of the preoperative administration of dexketoprofen trometamol (DKT) on the pain perceived by patients after oral surgery for implant…
- Trial name
- UMU (NCT03107338)
- Testing
- DEXKETOPROFEN TROMETAMOL
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Postoperative Pain, Dental Implant
Laser Photobiomodulation After Dental Implant Surgery: A Comparison of 650 nm and 810 nm Diode Lasers
The goal of this clinical trial is to evaluate the effectiveness of laser light therapy, known as photobiomodulation (PBM), in reducing pain after dental implant surgery.
- Trial name
- NCT06988722
- Testing
- 650 nm Diode Laser PBM, 810 nm Diode Laser PBM
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Institute of Laser Enhanced Sciences
Analgesia
Effectiveness of Pre-administered Natural Sweet-tasting Solution (Honey) for Decreasing Pain of Needle Insertion
This study aims to assess Effectiveness of Pre-administered Natural Sweet-tasting Solution (honey) for Decreasing Pain Associated with Dental Injections (infiltration) prior to dental extraction in 6-8 years old healthy Children…
- Trial name
- NCT06393777
- Testing
- honey
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis
Efficacy of Oral Prednisolone on Pain Reduction in Emergency Care of Acute Irreversible Pulpitis
Irreversible pulpitis is an inflammatory condition of the dental pulp, highly painful, representing one of the main reasons for consulting dental emergency.
- Trial name
- PULPISOLONE (NCT02629042)
- Testing
- Partial endodontic treatment under local and/or locoregional anesthesia, prednisolone
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Bordeaux
Pain, Postoperative
Preemptive Analgesia With Celecoxib for Acute Dental Pain Management
The purpose of this study is to compare the effect on postoperative pain of a single agent nonsteroidal anti-inflammatory drug (NSAID) [celecoxib plus placebo] to an NSAID combination [celecoxib plus acetaminophen] administered…
- Trial name
- NCT04790812
- Testing
- Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pulpitis, Pain Management
Effects of Topical Anesthesia Approaches on Dental Pain During and After Restorative Management of Dental Caries
The purpose of the Research Study and Overview of Participation: This study will compare different approaches used to prevent pain when giving local anesthesia to numb the teeth while managing dental cavities and decay.
- Trial name
- NCT07379515
- Testing
- Photobiomodulation (PBM)-induced analgesia device using multi-wavelength LED, Medicated analgesia
- Volunteers
- 204 people
- Sponsor
- Dubai Health
Symptomatic Irreversible Pulpitis (SIP), Dental Pain
Local Dexamethasone Administration in Symptomatic Irreversible Pulpitis
Symptomatic irreversible pulpitis is associated with a high incidence of inadequate pulpal anesthesia during endodontic treatment, particularly in mandibular molar teeth.
- Trial name
- SIPDEX (NCT07672873)
- Testing
- Saline (0.9%, sterile, for infusion), Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Anaesthesia, Dental Pain
Photobiomodulation and Tooth Analgesia
The purpose of this study is to test photobiomodulation (PBM) with a non-invasive light device for reducing discomfort during dental treatments in children.
- Conditions
- Dental Anaesthesia, Dental Pain, Dental Analgesia
- Trial name
- NCT06691269
- Testing
- Photobiomodulation, Topical Benzocaine, Local Anesthesia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Pain Management, Local Anaesthesia
Effectiveness of DentalVibe in Reducing Injection Pain and Anxiety During Local Anaesthesia in Children
The aim of this study is to determine the effectiveness of DentalVibe (DV) in reducing injection pain and anxiety associated with local anaesthesia in paediatric patients.
- Trial name
- NCT03445182
- Testing
- Local anaesthesia with conventional syringe, Local anaesthesia with conventional syringe + Dentalvibe
- Where
- Bulgaria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Anesthesia, Anxiety
Buzzy Bee for Pain and Anxiety Control During Pediatric Dental Local Anesthesia
The present study will evaluate the effectiveness of Buzzy Bee in reducing pain and physiological responses during maxillary buccal infiltration in children aged 5-7 years compared with a conventional injection protocol.
- Conditions
- Anesthesia, Anxiety, Pain, Children
- Trial name
- NCT07886333
- Testing
- Intervention A: Buzzy® Bee-Assisted Local Anesthesia, Intervention B: Conventional Local Anesthesia Technique
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Endodontic Treatment, Pulp Necrosis
Dexamethasone Treatment for Patients Undergoing Endodontics
This Phase IV randomized clinical trial (RCT) evaluated the efficacy of preoperative administration of a single 4 mg oral dose of dexamethasone in reducing postoperative pain and inflammation following endodontic treatment.
- Conditions
- Endodontic Treatment, Pulp Necrosis, Periapical Lesions, Postoperative Pain
- Trial name
- (DTPE-RCT) (NCT06906315)
- Testing
- Dexamethasone 4 mg, Ibuprofen group
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- University of Salamanca
Hemodynamics, Pain
Hemodynamic Effects of Different Vasoconstrictors in Mandibular Exodontia
Title of Study: The Effect of Different Vasoconstrictive Agents on Hemodynamics Among Patients Undergoing Simple Mandibular Exodontia: A Triple-Blind Randomized Controlled Trial Location: King Abdulaziz University Dental Hospital…
- Conditions
- Hemodynamics, Pain, ASA I-II Requiring Simple Dental Extraction of a Mandibular Tooth
- Trial name
- NCT07013071
- Testing
- 2% Mepivacaine with 1:100,000 epinephrine, 2% Mepivacaine with 1:55,000 Epinephrine Bitartrate
- Where
- Saudi Arabia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University