Clinical trials: Dental Anesthesia
Metabolic Acidosis, Antiepileptic Drugs
The Relationship of Developing Metabolic Acidosis With Antiepleptic Drugs in Craniotomy Operations
The relationship of developing metabolic acidosis with antiepleptic drugs in craniotomy operations
- Conditions
- Metabolic Acidosis, Antiepileptic Drugs, Craniotomy, Anesthesia Management
- Trial name
- NCT05940935
- Testing
- Arterial Blood Gas Base Deficit
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Trakya University
Anesthesia, Dental
Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Maxillary Procedures
This Phase 3 clinical study is designed as a multicenter, randomized, blinded, controlled study to evaluate the efficacy, pharmacodynamics, and safety of NV-101 administered as a submucosal injection following completion of a…
- Trial name
- NCT00309335
- Testing
- Phentolamine Mesylate (NV-101)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Novalar Pharmaceuticals, Inc.
Spine Surgery
Pregabalin Effects on Hypotensive Anesthesia During Spine Surgery.
Elective lumbar spine surgical procedures are commonly performed under controlled hypotension during general anesthesia. That is beneficial to limit the intraoperative blood loss and transfusions and improves surgical field.
- Trial name
- NCT03301025
- Testing
- Pregabalin
- Where
- 2 sites in Egypt
- Volunteers
- 106 people
- Sponsor
- Mansoura University
Perioperative Inflammatory Response, Postoperative Pain
Suprazygomatic Maxillary Nerve Block Effect on Systemic Inflammatory Response in Cleft Palate Surgeries
the aim is to determine the value of adding bilateral supra zygomatic maxillary nerve block to general anesthesia in attenuating the systemic inflammatory response in paediatrics.
- Trial name
- NCT05495750
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alaa Mohamed Abdel Salam Ibrahim Soliman
Throat Disorder
Pretreatment to Reduce Pain and Discomfort During Fiberoptic Nasal Pharyngoscopy and Laryngoscopy
Fiberoptic laryngoscopy (FOL) is one of the most common procedure done in an Ear Nose Throat (ENT) clinic. Topical anesthesia or decongestant or both have been used to improve patient comfort level during the procedure.
- Trial name
- NCT03620513
- Testing
- Decongestant (oxymetazoline 0.05%), Anesthesia (Lidocaine 15%), Decongestants and Anesthesia (oxymetazoline and lidocaine)
- Where
- Nepal
- Volunteers
- 160 people
- Sponsor
- Lumbini Medical College
Deep Sedation, Non-invasive Ventilation Support
Comparison of Nasal Continuous Positive Airway Pressure (CPAP) Mask and Nasal Airway in Molar Tooth Extraction Under Deep Sedation
In patients with high levels of fear and anxiety, it is recommended to perform dental procedures under sedation or general anesthesia depending on the nature of the procedure.
- Conditions
- Deep Sedation, Non-invasive Ventilation Support, Nasal Airway, Nasal CPAP Mask
- Trial name
- NCT06436638
- Testing
- Non-invasive ventilation support equipment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gözde Nur Erkan
Pain, Postoperative, Pain, Chest
Ideal Initial Bolus and Infusion Rate for Erector Spinae Plane Block Catheters
This study would like to identify the best starting dose and infusion rate for nerve blocks and nerve catheters related to the erector spinae plane block that can improve functional status and pain control on cardiac surgery…
- Trial name
- NCT03961048
- Testing
- Ropivacaine 0.2%-Sodium Chloride 0.9% Injectable Solution bilaterally, Ropivacaine 0.2%-Sodium Chloride 0.9% Injectable Solution unilaterally
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Anesthesia Refusal
A Comparative Evaluation of Nebulized Dexmedetomidine and Nebulized Ketamine as a Premedication in Pediatric Surgeries
preoperative anxiety and parental deprivation can be a traumatic time for young children undergoing surgery and remain challenges to anesthesiologists.
- Trial name
- NCT05719506
- Testing
- normal saline without drug, Dexmedetomidine, Ketamine
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Perfusion Index, Position Differences
Evaluation Of The Effects Of Changes In Operating Table Position On Perfusion Index And Spinal Anesthesia
The aim of this observational study is to investigate how table position affects the development of block in patients undergoing spinal anesthesia. Perfusion index measurements will be used to answer this question.
- Trial name
- Perfusion (NCT07400185)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Enes Celik
Delayed Emergence From Anesthesia
Recovery Profile Comparison Between Remifentanil-propofol or Desflurane Anesthesia Monitored With Bispectral Index.
Bispectral monitoring anesthesia with remifentanil-desflurane has a better post-operative recovery than remifentanil-propofol.
- Trial name
- NCT02631525
- Testing
- Desflurane, Propofol
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes
Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia
This study aims to evaluate topical application of Cocaine HCl 4% and 10% on safety and efficacy in local (topical) anesthesia for diagnostic procedures and surgeries on or through accessible mucous membranes of the nasal…
- Conditions
- Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes, of the Nasal Cavities
- Trial name
- NCT01746940
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.
Anesthesia
TEAS to Reduce Propofol Consumption During General Anesthesia
The study is aimed at whether transcutaneous electrical acupoint stimulation (TEAS) during general anesthesia could reduce the need for propofol in patients undergoing minor surgery.
- Trial name
- TOP (NCT02314650)
- Testing
- acupoint stimulation, non-acupoint stimulation, electrodes attached
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Air Force Military Medical University, China
Opioid Use, Bariatric Surgery Candidate
Evaluation of the Stress Response in Anesthesia Use Inhalation Anesthetic (Desflurane) Versus TIVA for Bariatric Surgery
The goal of this clinical trial is to compare the effects of Opioid Free Anesthesia (OFA) with and without volatile anesthetics (in this case desflurane) in patients undergoing bariatric surgery.
- Conditions
- Opioid Use, Bariatric Surgery Candidate, TCI Eleveld, Obesity
- Trial name
- NCT07568938
- Testing
- opioid free anesthesia, Opiod Free Anesthesia with TCI ELEVELD
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- G.Gennimatas General Hospital
Anesthesia
Auxiliary Anesthesia Technique for Extracting Advanced Hemodynamic Parameters Based on Peripheral Arterial Waveform Photography
In this study, the arterial blood pressure waveform was digitized by snapshots or videos of the patient monitor to further estimate advanced hemodynamic parameters, so as to realize continuous and automatic monitoring of advanced…
- Trial name
- NCT05961358
- Testing
- snapshots or videos of monitor, Pressure transducer
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anesthesia
Methadone in Pediatric Anesthesia
This study will determine the pharmacokinetics of intravenous (IV) methadone in children undergoing surgery.
- Trial name
- NCT00921843
- Testing
- Methadone 0.1mg/kg, Methadone 0.2mg/kg, Methadone 0.3mg/kg
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Washington University School of Medicine
Elective Reconstructive Surgery Population
The Effect of Healing Touch on Sleep
Healing Touch improves measures of sleep the night prior to surgery, thus improving surgery-related morbidity.
- Trial name
- Sleep7 (NCT01870076)
- Testing
- Healing Touch, Control, Presence
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Anesthesia
Automated UltraSound Software for Identification of Lumbar Vertebral Levels
A novel automated ultrasound software system has been developed which identifies for the practitioner the intervertebral spaces in the lumbar area.
- Trial name
- AUSSI (NCT02982317)
- Testing
- Manual palpation identification lumbar spine, Automated ultrasound technology identification, Lumbar level identification gold standard ultrasound
- Where
- Canada
- Volunteers
- 77 people
- Sponsor
- University of British Columbia
Sevoflurane, Desflurane
To Compare the Consumption of Sevoflurane and Desflurane in Low Flow Anaesthesia
This prospective observational study aims to compare sevoflurane and Desflurane consumption in low-flow anaesthesia using the ASA (American Society of Anaesthesiology). Environmental Sustainability Committee recommendations.
- Trial name
- NCT06602947
- Testing
- Low flow anaesthesia using ASA enviormental sustanibility commitee recomendation
- Where
- India
- Volunteers
- 564 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Stress, Pain
Evaluation of the Surgical Pleth Index During Spinal and General Anesthesia
The Surgical Pleth index (SPI) has been introduced as a non invasive tool to "measure" stress and pain during surgery. Preliminary studies were performed in patients under general anaesthesia with propofol and remifentanil.
- Trial name
- NCT00789438
- Where
- Germany
- Volunteers
- 69 people
- Sponsor
- University Hospital Schleswig-Holstein
Obesity, Anesthesia
Optimal Anesthesia for Morbidly Obese Patients
Obese patients have a higher risk of anesthesia compared to the non-obese, including difficult intubation, rapid desaturation, difficult vascular access, and delayed recovery from anesthesia.
- Trial name
- NCT04395248
- Testing
- Exploring potential risk factors of difficult intubation using ultrasound, Radial artery catheterization using ultrasound guidance or blind palpation, Comparing the effectiveness of preoxygenation between high-flow nasal cannula and facemask
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital