Clinical trials: Dental Anesthesia Efficacy
Other Acute Postoperative Pain
Paracetamol Versus Dipyrone After Pediatric Lower Abdominal Surgery in Children With Spinal Anesthesia
We conducted a prospective, randomized double-blind study to compare the effectiveness of intravenous paracetamol and dipyrone for preventing pain during early postoperative period in school-age children undergoing lower…
- Trial name
- NCT01858402
- Testing
- Paracetamol, Dipyrone
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Baskent University
Pain
Post-operative Pain Management In Patients Undergoing Hullax Valgus Surgery
The purpose of this study is to investigate the efficacy and cost analysis of intravenous fentanyl combined with either local anesthesia infiltration or peroneal nerves block in patients with Hallux Valgus undergoing orthopedic…
- Trial name
- NCT01960595
- Testing
- IV fentanyl PCA, local bupivacaine infiltration and post-OP IV fentanyl PCA, Nerve Blocks and post-OP IV fentanyl PCA
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Postoperative Pain
Comparison of the Efficacy of PENG Block in Combination With LFCN Block and Wound Infiltration
The ultrasound-guided approach for the blockade of articular branches of femoral and obturator nerves, pericapsular nerve group (PENG) block, is an effective method for postoperative analgesia in hip surgeries.
- Trial name
- NCT04681222
- Testing
- LFCN, Wound infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Derince Training and Research Hospital
Vertebral Compression Fractures in Osteoporotic Patients
Efficacy of Fluoroscopy-guided Epidural Anesthesia for Osteoporotic Vertebral Compression Fracture Treated by Percutaneous Vertebroplasty
Vertebral compression fractures in osteoporotic patients is a major healthcare problem. Percutaneous vertebroplasty is commonly used to restore stability of the vertebra and to alleviate pain.
- Trial name
- VTB EPI-AL (NCT03621527)
- Testing
- anesthesia combined with intravenous analgesia by remifentanil, fluoroscopy-guided epidural anesthesia
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Patients Undergoing Elective Craniotomy
Efficacy of Adding Low Dose Ketamine or Fentanyl to Propofol-dexmedetomidine as Total Intravenous Anesthesia
Efficacy of adding low dose ketamine or fentanyl to propofol-dexmedetomidine as total intravenous anesthesia for patients undergoing craniotomy in supra tentorial brain tumor
- Trial name
- TIVA (NCT06031883)
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Postoperative Pain
Caudal Block for Inguinal Hernioplasty in Children
This is a prospective, randomized, controlled clinical study designed to determine the effectiveness of caudal block combined with general anesthesia in providing intra- and postoperative analgesia, and its effect on hemodynamic…
- Trial name
- NCT05958589
- Testing
- Caudal block with levobupivacaine, General anesthesia, Inguinal hernioplasty
- Where
- Serbia
- Volunteers
- 70 people
- Sponsor
- University of Novi Sad
Insomnia
Study on the Efficacy and Safety of Anesthesia-Induced Sleep Therapy for Refractory Insomnia
The incidence of refractory insomnia is rising annually, with traditional therapies offering limited efficacy. Anesthesia-Induced Sleep (AIS), involving anesthetic infusion like dexmedetomidine, is emerging.
- Trial name
- NCT07255027
- Testing
- Dexmedetomidine and conventional oral drug, Conventional oral drug therapy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Hypotension After Spinal Anesthesia, Hypotension During Cesarean Delivery
Comparison of the Efficacy of Continuous Metaraminol Infusion Versus Continuous Norepinephrine Infusion for the Prevention of Hypotension During Cesarean Section Under Spinal Anaesthesia. A Randomised Controlled Trial.
The aim of this double-blind randomised study will be to compare a fixed-rate prophylactic metaraminol infusion to a fixed-rate prophylactic norepinephrine infusion during elective cesarean section under combined spinal-epidural…
- Trial name
- NCT07363109
- Testing
- Metaraminol infusion, Norepinephrine infusion
- Volunteers
- 80 people
- Sponsor
- Aretaieion University Hospital
Anesthesia, IVF
Does Camel Milk Consumption Decrease The Efficacy Of Midazolam For Sedation
The primary aim is to verify if camel milk consumption has an impact on the amount of Midazolam needed to achieve a satisfactory level of sedation for oocyte retrieval, compared to patients never having consumed camel milk.
- Trial name
- NCT04397393
- Testing
- Midazolam
- Where
- United Arab Emirates
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Airway Management
Compare the Efficacy of Different Laryngeal Mask Size Selection Methods in General Anesthesia in Children
The laryngeal mask is widely used in general anesthesia in children. Selection of an appropriately sized laryngeal mask airway (LMA) is critical to ensure safe and effective use of the device.
- Trial name
- NCT03845998
- Testing
- use the three-finger method, use the weight-related method
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Anesthesia, Hip Fracture Surgery
Efficacy of Perioperative Anesthesia Care Bundle on Prognosis in Elderly Undergoing Hip Fracture Surgery
This study is going to research the hypothesis that to strengthen the comprehensive treatment of perioperative anesthesia is possible to improve the prognosis of patients with hip fracture and reduce mortality.
- Conditions
- Anesthesia, Hip Fracture Surgery, Nursing
- Trial name
- EPAPHUS (NCT03429010)
- Testing
- New "guideline" anesthesia strategy team
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Postoperative Nausea and Vomiting
Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Vitrectomy Under Local Anesthesia
Vitreoretinal surgery is associated with a considerable incidence of postoperative nausea and vomiting (PONV), which is reported to be as high as 60%.
- Trial name
- NCT02386059
- Testing
- Dexamethasone, Ondansetron, Dexamethasone + Ondansetron
- Where
- 4 sites in Italy
- Volunteers
- 1,200 people
- Sponsor
- University of Catania
Anesthesia, General
Comparison of Sugammadex With Neostigmine During Laparoscopic Cholecystectomy or Appendectomy (P05699)
The current trial was designed to demonstrate faster recovery from a neuromuscular blockade (NMB) induced by rocuronium after reversal at 1-2 Post Tetanic Count (PTC) by 4.0 mg.kg-1 sugammadex compared to 50 µg.kg-1 neostigmine…
- Trial name
- NCT00724932
- Testing
- Rocuronium, Sugammadex, Neostigmine
- Volunteers
- 140 people
- Sponsor
- Merck Sharp & Dohme LLC
ERCP
Conscious Sedation Versus Anesthesia for ERCP
Studies directly comparing EDCS with AAS during ERCP are scarce, varying widely in their designs and reaching conflicting conclusions regarding safety and effectiveness.
- Trial name
- NCT05220774
- Where
- Canada
- Volunteers
- 3,174 people
- Sponsor
- University of Calgary
Pediatric Anesthesia, Airway Management
Effective Dose of Alfentanil Combined With Propofol for Laryngeal Mask Airway Insertion in Children
This study uses a prospective, up-and-down sequential allocation method to determine the median effective dose (ED50) and 95% effective dose (ED95) of alfentanil combined with propofol for successful laryngeal mask airway (LMA)…
- Conditions
- Pediatric Anesthesia, Airway Management, General Anesthesia, LMA
- Trial name
- NCT07581665
- Testing
- Alfentanil
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Anesthesia, Local
Efficacy of Transversus Abdominis Plane Block
This study aims to assess the efficacy of Transversus Abdominus Plane (TAP) blocks, a well-established anesthetic technique, to decrease the amount of post-operative pain in patients who undergo minimally invasive gynecologic…
- Trial name
- NCT06274307
- Testing
- Transversus abdominis plane block
- Where
- 2 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Justin Hruska
Femoral Neck Fractures, Regional Anesthesia
Comparison of Regional Anaesthesia Methods for Femoral Neck Fracture Surgery
Femoral fracture surgery is frequently performed especially in geriatric population. Compared to general anaesthesia, regional anaesthesia is preferred to general anaesthesia in the geriatric patient population due to lower…
- Trial name
- NCT06224439
- Testing
- hypobaric spinal anaesthesia, lumbar plexus block, hyperbaric spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Arthropathy of Hip, Hip Osteoarthritis
Comparison of Spinal Anesthesia With Intrathecal Morphine Versus PENG Block With or Without Dexamethasone in Hip Arthroplasty
The goal of this clinical trial is to learn which of three regional anesthesia approaches provides better pain relief and safety for older adults having planned hip replacement surgery.
- Trial name
- THA (NCT07584200)
- Testing
- Intrathecal Morphine, Pericapsular Nerve Group Block, Dexamethasone
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Colorectal Cancer
Xenon Combined With Intraoperative Thoracic Epidural Analgesia
This is a monocentric study in 2 steps: A safety part to assess the feasibility of using Xenon in association with a thoracic epidural analgesia (TEA) with a sequential recruitment of 3, 6 or 9 patients according to predefined…
- Trial name
- NCT01696630
- Testing
- Xenon, Desflurane
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Centre Leon Berard
Anesthesia, Gynecologic Cancer
ESP vs TAP in Total Laparoscopic Hysterectomy
The anesthetic techniques for videolaparoscopic surgery include general anesthesia, and locoregional anesthesia in association with general anesthesia in order to reduce or abolish post-operative pain with a simultaneous…
- Trial name
- ARTEMIDE (NCT04839445)
- Testing
- General anesthesia + TAP block, General anesthesia + ESP block
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- AUSL Romagna Rimini