Clinical trials: Dental Anesthesia Efficacy
Hip Fractures, Postoperative Pain
Evaluation of the Effectiviness of Two Different Bupivacaine Concentrations of the Pericapsular Nerve Group (PENG) Block
The use of regional anaesthesia techniques as part of multimodal analgesia in hip surgeries improves postoperative analgesia. PENG (Pericapsular nerve group) block is an effective motor sparing analgesia technique used in hip…
- Trial name
- PENG (NCT05921110)
- Testing
- Pericapsular nerve group block 0,25%, Pericapsular nerve group block 0,16%
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ilker Ital
Osteoarthritis, Knee, Postoperative Pain
A Randomized Comparison of the Efficacy of the IPACK Block Versus the Popliteal Plexus Block for Posterior Knee Analgesia, in Patients Undergoing a Total Knee Arthroplasty and Receiving a Continuous Distal Femoral Triangle Block
Total knee arthroplasty (TKA) is commonly associated with significant postoperative pain, including pain arising from the posterior aspect of the knee.
- Trial name
- NCT07876310
- Testing
- Ultrasound-Guided iPACK Block, Ultrasound-Guided Popliteal Plexus Block, Ultrasound-Guided Continuous Femoral Triangle Block
- Volunteers
- 136 people
- Sponsor
- Clinica Santa Maria
Sacral Erector Spinae Plane Block, Pediatric Regional Anesthesia
Sacral Erector Spinae Plane Block Versus Penile Block For Analgesia In Pediatric Circumcision
Circumcision is one of the most frequently performed surgical procedures in childhood and is associated with significant postoperative pain.
- Conditions
- Sacral Erector Spinae Plane Block, Pediatric Regional Anesthesia, Regional Anaesthesia
- Trial name
- NCT07321717
- Testing
- Sacral Erector Spinae Plane Block, Penile Nerve Block (PNB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Postoperative, ACL Injury
Effectiveness of iPACK on Postoperative Pain From Hamstring Autograft Following ACL Repair
Patients undergoing ACL repair with hamstring autograft frequently develop significant post operative pain at the hamstring grafting site.
- Conditions
- Pain, Postoperative, ACL Injury, Anesthesia, Local, Opioid Use
- Trial name
- NCT05080348
- Testing
- Ropivacaine iPACK Injection, Normal Saline iPACK Injection
- Volunteers
- 40 people
- Sponsor
- Brenton Alexander
Urolithiasis
Analysis of the Effectiveness and Safety of RIRS Under Local Anesthesia and Its Influencing Factors
Retrograde intrarenal surgery (RIRS) is a well-established technique and is the first-line treatment option for upper urinary tract stones <2cm.
- Trial name
- NCT06737497
- Testing
- retrograde Intrarenal Surgery ( RIRS ) under local anesthesia
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Anesthesia, General
A Bridging Trial Comparing Sugammadex (Org 25969) at Reappearance of T2 in Japanese and Caucasian Participants. Part B: Caucasian Participants (P05971)
The objective of the trial was to establish the dose-response relation of sugammadex (Org 25969) given as a reversal agent of rocuronium or vecuronium at reappearance of T2 (the amplitude of the first response of second twitch to…
- Trial name
- NCT00552617
- Testing
- Sugammadex, Rocuronium, Vecuronium
- Volunteers
- 100 people
- Sponsor
- Merck Sharp & Dohme LLC
Ultrasound Guided Nerve Block, Anesthesia , Analgesia
Comparative Study Between Ultrasound Guided Regional Anesthesia for Awake Tympanoplasty Surgery vs General Anesthesia
The aim of this study to evaluate efficacy of ultrasound guided regional anesthesia in performing awake tympanoplasty surgery versus traditional general anesthesia
- Trial name
- NCT07275450
- Testing
- Ultrasound-guided regional anesthesia group, Control group
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Bronchoscopy, Procedural Sedation
Ciprofol Versus Propofol With Low-Dose Sufentanil for Painless Bronchoscopy
Bronchoscopy may cause coughing, discomfort, body movement, and changes in breathing or blood pressure. Propofol is commonly used for sedation during bronchoscopy, but it may cause respiratory depression, circulatory depression…
- Trial name
- NCT07744061
- Testing
- Ciprofol, Propofol, Sufentanil
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Wenzhou Central Hospital
Postoperative Pain
Regional Anesthesia in THR - Comparing the Analgesic Efficacy of Fascia Iliaca Block and Erector Spinae Plane Block
THR (Total Hip Replacement) can be very painful and regional anesthesia is very effective in reducing postoperative pain. Fascia Iliaca Block (FIB) and Erector Spinae Plane Block (ESPB) are indirect approaches to the lumbar…
- Trial name
- PTA-ALR (NCT04574154)
- Testing
- FIB, ESPB, spinal anesthesia
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Papa Giovanni XXIII Hospital
Bronchoscopy, Anesthesia
An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Flexible Bronchoscopy
Very often patients receive medication before a diagnostic, therapeutic, or surgical procedure to help them relax, keep them calm, and to relieve them from pain. This is called procedural sedation.
- Trial name
- NCT00306722
- Testing
- AQUAVAN® (fospropofol disodium) Injection
- Where
- 25 sites in United States
- Volunteers
- 250 people
- Sponsor
- Eisai Inc.
Traumatic Rib Fracture
Thoracic Blocks Versus Thoracic Epidural and Patient Controlled Anesthesia in Traumatic Rib Fracture Patients
The primary objective of this study is to investigate whether continuous PVB is equal in efficacy to epidural anesthesia in terms of analgesia in patients with INR lower than 1.2, or is continuous ICNB equal in efficacy to PCA in…
- Trial name
- NCT01599403
- Testing
- Paravertebral Block, Intercostal Nerve Block, Epidural Block
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Regional Anaesthesia, Anesthesia and Analgesia
Comparison of the Efficacy of Celiac Plexus Blockade, ESP and Lidocaine Infusion Under OFA
Modern anesthesiology, in search of alternatives to opioid-based pain management, is turning to low-opioid and non-opioid protocols.
- Trial name
- LECO (NCT06793527)
- Testing
- Celiac Plexus Block, ESP block, Lidacaine
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Jagiellonian University
Nerve Blocks, Breast Surgery
Efficacy of Pectoral Nerve Block for Breast Reduction Surgery
The purpose of the study is to evaluate the efficacy of PECS block applied to patients undergoing bilateral breast reduction surgery on postoperative analgesia compared to local infiltration anesthesia.
- Conditions
- Nerve Blocks, Breast Surgery, Postoperative Pain
- Trial name
- NCT03857386
- Testing
- PECS group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Antalya Training and Research Hospital
Anesthesia
Efficacy and Safety of HSK3486 Compared to Propofol in Induction of General Anesthesia in Adults Having Elective Surgery
This is a multicenter, randomized, double-blinded, propofol-controlled, Phase 3 clinical study to evaluate the efficacy and safety of HSK3486 for induction of general anesthesia in adults undergoing elective surgery.
- Trial name
- NCT04711837
- Testing
- HSK3486, Propofol
- Where
- 13 sites in United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Haisco-USA Pharmaceuticals, Inc.
Local Anesthesia
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection
This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution…
- Trial name
- NCT05473819
- Testing
- Buffered Local Anesthesia, Conventional Unbuffered Local Anesthesia
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Pain
Comparison Between the Analgesic Effectiveness of Virtual Reality and Topical Anesthesia: A Clinical Study
A split-mouth, controlled trial aimed to clinically compare and evaluate the effectiveness of virtual reality versus topical anesthesia gel prior to administration of dental anesthesia injection in reducing the perceived pain and…
- Trial name
- NCT04919421
- Testing
- Dental injection and topical gel application, Dental injection and virtual reality device
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Depressive Disorder, Major, Treatment Resistant Depression
Efficacy of Deep Anaesthesia With Isoflurane as a Fast-response Antidepressant Agent
In this study the investigators will submit patients with treatment resistant depression to deep anesthesia with isoflurane to get 15 minutes of cortical burst suppression on electroencephalogram, once a week for six weeks.
- Conditions
- Depressive Disorder, Major, Treatment Resistant Depression, Depressive Episode
- Trial name
- ISORADAR (NCT04171193)
- Testing
- Isoflurane, Sertraline Pill
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Reversal of Neuromuscular Blockade
Efficacy and Safety of Sugammadex in Thoracoscopy Thymectomy for Chinese Adults With Myasthenia Gravis
The purpose of this study was to demonstrate in patients with myasthenia gravis (MG) undergoing thoracoscopic thymectomy faster recovery from a moderate neuromuscular block induced by rocuronium after reversal at reappearance of…
- Trial name
- NCT06436768
- Testing
- Sugammadex, Neostigmine
- Where
- 2 sites in China
- Volunteers
- 62 people
- Sponsor
- Beijing Tongren Hospital
Hernia Inguinal, Pain Postoperative
Predictive Factors for the Effectiveness of the Ilioinguinal Iliohypogastric Nerve Block for Hernia Surgery
Inguinal hernia repair is a common surgical procedure done as day surgery. Because patients need to be discharged on the same day, the choice of anesthesia technique is influenced.
- Conditions
- Hernia Inguinal, Pain Postoperative, Regional Anesthesia
- Trial name
- VALI (NCT06121726)
- Testing
- Ilioinguinal-Iliohypogastric nerve block, Local anesthetic
- Where
- Italy
- Volunteers
- 343 people
- Sponsor
- University of Padova
Mastectomy, Postoperative Pain
Comparison of Postoperative Analgesic Effectiveness of Superficial and Deep Serratus Plane Blocks for Mastectomy
Pain after breast surgery can be quite severe and can significantly affect quality of life. By successfully treating acute pain, it is aimed to prevent the formation of pain memory and to ensure that chronic pain never occurs.
- Conditions
- Mastectomy, Postoperative Pain, Analgesia
- Trial name
- NCT06438211
- Testing
- superficial or deep serratus anterior plane block for mastectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- TC Erciyes University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.