Clinical trials: Dental Anesthesia Efficacy
Anesthesia Induced Hypotension, Hypotension Drug-Induced
Comparison of Pleth Variability Index vs. Diastolic Shock Index for Predicting Hypotension During Anesthesia Induction
This study aims to explore the frequent occurrence of hypotension during anesthesia induction due to anesthetic drugs or fasting. Predicting this condition is important for patient safety and anesthesia management.
- Trial name
- NCT06589674
- Testing
- Pulse variability index measurement, Diastolic shock index
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Kocaeli City Hospital
Assessing the Effect of Acupoint Massage on Pain and Anxiety in Patients Undergoing Surgery Under Local Anesthesia
The Effectiveness of Acupressure on the Physiological and Psychological Improvement of Patients Undergoing Local Anesthesia
Background: Local anaesthesia surgeries are outpatient procedures that allow patients to go home the same day. However, these surgeries often cause pain and anxiety for patients.
- Trial name
- LA (NCT06681519)
- Testing
- Experimental Group 1 - Acupoint Pressure Experimental Group 2 - Pressure Ball Control Group - Conventional Treatment
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Yu-Jui Feng
Pain Management, Endoscopy, Gastrointestinal
Construction and Effectiveness Evaluation of Painless Digestive Endoscopy Mode Led by Anesthesia Nurses Under the Guidance of Anesthesiologists
The purpose is to verify the effectiveness and safety of the painless digestive endoscopy mode led by anesthesia nurses under the guidance of anesthesiologists.
- Trial name
- NCT06712264
- Where
- China
- Volunteers
- 18,000 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Intubation, Anesthesia
Comparative Efficacy of Intravenous Labetalol and Lignocaine in Mitigating Hemodynamic Responses to Laryngoscopy During Laparoscopic Cholecystectomy
Laryngoscopy and intubation during laparoscopic cholecystectomy often cause sudden increases in heart rate and blood pressure, which can be harmful in some patients.
- Conditions
- Intubation, Anesthesia, Laparoscopic Cholecystectomy, Hemodynamic Response to Laryngoscopy
- Trial name
- LAB-LIG RCT (NCT07192081)
- Testing
- Labetalol, Lignocaine
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Dr. Waseem Ullah
Post-Surgical Complication
Comparsion of IV Dexmedetomidine, Tramdol and Ketamine for Post Spinal Anesthesia Shivering.
To study control of post spinal shivering in patients undergoing lower segment cesarean section using dexmedetomidine, tramadol and ketamine
- Trial name
- NCT05311722
- Testing
- Dexmedetomidine, Ketamine, Tramadol
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Sheikh Zayed Medical College
Scrotum Disease, Hydrocele Male
Efficacy of Inhaled Methoxyflurane (Penthrox) as Adjunct for Urologic Procedures Under Local Anesthetic: A Pilot Study
We wish to perform a prospective randomized controlled pilot study at the Men's Health Clinic and Health Science's Centre to assess whether or not the use of Penthrox as an adjunct to LA is associated with improved pain tolerance…
- Conditions
- Scrotum Disease, Hydrocele Male, Spermatocele, Scrotal Hematocele
- Trial name
- NCT07192198
- Testing
- Methoxyflurane, Control
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hypothermia
Effectiveness of Nefopam for Thermoregulation During Surgery
Nefopam may help blunt thermoregulatory defenses, thus facilitating induction of therapeutic hypothermia
- Trial name
- NCT03122665
- Testing
- Nefopam Low dose, Nefopam High dose
- Where
- Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Acute Pain
Clinical Efficacy of Prophylactic Intravenous Neostigmine and Atropine in Preventing Post-Dural Puncture Headache Among Parturient Undergoing Spinal Anesthesia for Cesarean Section: A Double-blind Randomized Placebo-controlled Trial
Post dural puncture headache is a distressing issue, many measures tried to treat symptoms but few delt with prevention.
- Trial name
- NCT06493838
- Testing
- intravenous 50 mL of saline injection of 0.9% after umbilical cord clamping., Neostigmine 20μg/kg (Neostigmine Methylsulphate 0.5 mg, Amriya Pharm.Ind.) and atropine 0.01 mg/kg (diluted in 50 ml saline; 0.9% for 10 min) following umbilical cord clamping.
- Volunteers
- 180 people
- Sponsor
- Minia University
Femur Neck Fracture, Spinal Anesthesia
Comparison of Unilateral Spinal Anesthesia and Nerve Block in Hip Fractures
This randomized study aims to compare the efficacy and hemodynamic effects of hypobaric unilateral spinal anesthesia (HUSA) and lumbar plexus block (LP-SP) in patients undergoing femoral neck fracture surgery.
- Conditions
- Femur Neck Fracture, Spinal Anesthesia, Lumbar Plexus Nerve Block
- Trial name
- NCT07272226
- Testing
- Hipobaric Unilateral Spinal Anesthesia Group, Lumbar Plexus Block (LP-SP)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Anesthesia Intubation Complication, Difficult Intubation
Safety and Efficacy of Cleverscope. A New Medical Device for Tracheal Intubation
Cleverscope is a new medical device that transform a laryngoscope into a videolaryngoscope. previous its commercialization we evaluate its safety and efficacy.
- Trial name
- NCT03902704
- Testing
- Cleverscope, Laryngoscope / Videolaryngoscope C-MAC® Storz
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- Hospital General Universitario de Valencia
Nerve Blocks, Breast Surgery
Efficacy of Pectoral Nerve Block for Breast Reduction Surgery
The purpose of the study is to evaluate the efficacy of PECS block applied to patients undergoing bilateral breast reduction surgery on postoperative analgesia compared to local infiltration anesthesia.
- Conditions
- Nerve Blocks, Breast Surgery, Postoperative Pain
- Trial name
- NCT03857386
- Testing
- PECS group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Antalya Training and Research Hospital
PONV
Prophylactic Antiemetic Efficacy of Palonosetron Versus Ondansetron for Cesarean Sections Under Regional Anesthesia
This study aims to compare the quality of perioperative antiemesis of palonosetron and ondansetron in patients undergoing cesarean section
- Trial name
- PONV (NCT02468323)
- Testing
- Ondansetron, Palonosetron
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Hospital de Base
Obesity, Anesthesia
Pre-oxygenation Methods in Bariatric Patients
The purpose of the study is to compare effectiveness of different methods of achieving pre-oxygenation in bariatric patients. The investigators intend to compare facemask pre-oxygenation with a high-flow humidified nasal oxygen.
- Conditions
- Obesity, Anesthesia, Bariatric Surgery Candidate
- Trial name
- NCT03428256
- Testing
- Optiflow and THRIVE technique, Standard anaesthetic face mask
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Pain, Joint, Knee Arthropathy
Comparison Of The Analgesic Efficacy Of IPACK (Interspace Between The Popliteal Artery And Capsule Of The Posterior Knee) Block Alone And IPACK Block Combined With Genicular Block In Patients Planned For Total Knee Arthroplasty
The IPACK (interspace between the popliteal artery and capsule of the posterior knee) block is a regional anesthesia technique in which a local anesthetic is infiltrated under ultrasound guidance between the popliteal artery and…
- Conditions
- Pain, Joint, Knee Arthropathy, Anesthesia, Orthopedic Disorder
- Trial name
- NCT06065878
- Testing
- IPACK + Genicular Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cenk Gacemer
Anesthesia, Catheter Blockage
The Efficacy of Continuous Femoral Nerve Catheter Orifice Configuration for Postoperative Analgesia in Knee Arthroplasty
Femoral nerve catheter for postoperative analgesia will be included in the adult patients undergoing total knee arthroplasty included in the study.
- Conditions
- Anesthesia, Catheter Blockage, Knee Arthropathy, Pain, Postoperative
- Trial name
- NCT04202250
- Testing
- CEMP (closed-ended multiport catheter) group, OESP (open-ended single port catheter) group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gulhane School of Medicine
Regional Anesthesia, Pain, Postoperative
Analgesic Efficacy of Single-shot Erector Spinae Block for Thoracic Surgery
The erector spinae plane (ESP) block is a novel regional anesthetic technique for the treatment of thoracic, cervical, and abdominal pain.
- Trial name
- AnESTh (NCT03419117)
- Testing
- ESP block
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Total Knee Arthroplasty, Pain Management
Analgesic Efficacy of Preemptive Stepwise Infiltration Anesthesia for Perioperative Analgesia After TKA
This is a single-center prospective cohort study in which patients were evaluated by inclusion and exclusion criteria before total knee arthroplasty (TKA).
- Trial name
- NCT06600815
- Testing
- preemptive stepwise infiltration anaesthesia(PSIA), postoperative local infiltration analgesia(PLIA)
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Long-term-opioid-free Anesthesia
Long-term-opioid-free Anesthesia in Anterior Cervical Surgery
We design this randomized controlled trial to explore the safety and efficacy of the long-term-opioid-free anesthesia in anterior cervical surgery, to reduce the dosage of perioperative long-acting opioids and promoting…
- Trial name
- NCT05548465
- Testing
- Remifentanil Hydrochloride, Sufentanil Citrate
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Orthopedic Disorders, Foot Diseases
Efficacy of Ultrasound-Guided Local Anesthetic Injection Into or Around the Sciatic Nerve for Lower Limb Anesthesia
This study was designed to assess whether the injection of local anesthetic into the nerve (intraneural), as opposed to around it (perineural), requires a shorter time to develop surgical anesthesia of the lower leg.
- Conditions
- Orthopedic Disorders, Foot Diseases, Injuries, Leg, Injuries, Foot
- Trial name
- NCT01999647
- Testing
- Intraneural Injection for Subgluteal Sciatic Nerve Block, Perineural Injection for Subgluteal Sciatic Nerve Block, Femoral Nerve Block
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- University of Parma
Anesthesia
Efficacy and Safety of Optimal Muscle Tension Management During Laparoscopic Cholecystectomy
Our study is intended to compare optimal muscle tension management or conventional anesthetic management in laparoscopic cholecystectomy about surgical condition during the surgery and other conditions after surgery at POR.
- Trial name
- NCT04165057
- Testing
- Optimal muscle tension management
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
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