Clinical trials: Dental Caries
Dental Caries, Obesity Risk
Mothers' Action Project for Child Health
This randomized controlled trial will recruit Bangladeshi mothers and their young children into a 12 month intervention that provides child health and oral health education and seeks to build social networks among mothers.
- Trial name
- MAP-CH (NCT06753669)
- Testing
- health education and social network building, dental referral and educational materials
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Caries
Clinical Evaluation of SI-R21204 Versus Nano-hybrid Resin Composite: A Prospective Controlled Clinical Trial
Despite the advances in adhesive restorative techniques and materials, dental caries still remains a critical concern even today.
- Trial name
- NCT02823769
- Testing
- SI-R21204 resin composite, Nanohybrid resin composite
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Caries,Dental
Microbial Sampling of Carious Dentin
The School of Dentistry is seeking to determine whether viable microorganisms remain within tooth structure after conventional, mechanical removal of areas of tooth decay, prior to placement or replacement of tooth restorations…
- Trial name
- NCT04011605
- Testing
- Biological Sample of Carious Dentin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Utah
Artificial Intelligence, Education
Impact of Training Dental Students for an AI-Based Platform
The emergence of artificial intelligence (AI) and specifically deep learning (DL) have shown great potentials in finding radiographic features and treatment planning in the field of cariology and endodontics .
- Trial name
- NCT05912361
- Testing
- receiving a one hour theoretical and hands on training session before using an AI-based platform
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Caries, Plaque
Dental Plaque Microbiota in Caries-free and Caries-active Children
Dental caries is a polymicrobial infection originally thought to be caused by Streptococcus mutans and Lactobacilli. However, unprecedented developments in modern molecular techniques have demonstrated that several microbial…
- Trial name
- NCT03906981
- Testing
- Plaque from each subject will be collected but there will be no intervention
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Caries, Dental, Risk Reduction
Using a Mouthwash Containing Propolis, Clove Oil and Chlorhexidine to Improve the Caries Risk of High Risk Patients
This study is conducted to determine if using a mouthwash containing propolis, clove oil and chlorhexidine will improve the caries risk of high risk patients in comparison to using a mouthwash containing chlorhexidine only.
- Trial name
- NCT03553628
- Testing
- Chlorhexidine, Propolis and Clove Oil mouthwash, Chlorhexidine mouthwash
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Moataz Gamal Ali Abdul-Maksoud Konsouh
Caries,Dental
Photobiomodulation on Major Salivary Glands in Children With Caries Activity
The purpose of this trial is to evaluate the efficacy of photobiomodulation of the major salivary glands on salivary parameters in children with caries activity.
- Trial name
- NCT05546528
- Testing
- Photobiomodulation
- Where
- Uruguay
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dental Caries
Effect of Silver Diamine Fluoride and LED Activation on Residual Caries Activity in Class II Cavities
This observational clinical study investigates the effect of silver diamine fluoride (SDF) and its activation with light-emitting diode (LED) on residual caries activity after caries excavation in Class II primary molar cavities.
- Trial name
- NCT07250009
- Testing
- DIAGNOdent measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Dental Caries
Use of Antibacterial Cement in Infected Dentin
Dental materials with antibacterial properties can prevent the harmful effects caused by oral cariogenic bacteria. This double-blind controlled clinical trial evaluated the performance of antibacterial cement for sealing infected…
- Trial name
- AC (NCT01449136)
- Testing
- Antibacterial cement
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Pernambuco
Deep Carious Lesions
SDF Modified Hall Technique Vs. Conventional Pulpotomy for Management of Carious Primary Molars
Dental caries in primary teeth is considered the most common oral disease of childhood and it has been investigated in many places throughout the world.
- Trial name
- NCT05240365
- Testing
- SDF modified Hall technique, Conventional pulpotomy and stainless steel crown
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sondos Naserallah
Dental Caries
Cost-efficacy of Sealing Moderate Caries Lesions in Occlusal Surfaces of Primary Molars
This protocol aims to assess the cost-efficacy and applicability of the treatment of lesions moderate caries using sealants as an alternative to the restorations on occlusal surfaces of deciduous teeth.
- Trial name
- NCT03005405
- Testing
- Ionomer Restoration (control), Ionomer Sealant (test), Oral hygiene orientation and professional fluoride application
- Where
- Brazil
- Volunteers
- 96 people
- Sponsor
- University of Sao Paulo
Dental Caries, Tooth Demineralization
Kissing as a Protective Factor Against Acidic pH in Saliva
The pH of saliva can be acidic or alkaline; When it is acidic, the tooth enamel is demineralized, that is, weakened. Additionally, bacteria in the mouth can increase and cause infections such as cavities.
- Conditions
- Dental Caries, Tooth Demineralization, Teeth Erosion Limited to the Enamel
- Trial name
- NCT06501729
- Testing
- Kiss
- Where
- Ecuador
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universidad Catolica Santiago de Guayaquil
Composite Resin, Dental Caries in Children
Nano-Hybrid vs Bulk-Fill Resin Composites
The aim of this study is to compare the 2-year clinical performance of bulk-fill composites, which can be applied as a single layer, and the nano-hybrid filled composite resins, which are frequently used in clinical routine, in…
- Trial name
- NCT05432258
- Testing
- Bulk-fill composite resin, Nano-fill composite resin
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Dental Caries, Dentin Sensitivity
Comparative Evaluation of the Post Operative Sensitivity of Cention-N(Commercially Available Restorative Material) Using Conventional and Polymer Bur- In-vivo Study
Cention-N(commercially available restorative material) is a cost effective restoration for posterior restorations. Post-operative sensitivity is of great concern as far as any type of restorative material is concerned.
- Trial name
- NCT05185206
- Testing
- Class 1 cavity preparation using conventional steel bur and restoration with Cention-n(commercially available restorative material)., Class 1 cavity preparation using polymer bur and restoration with Cention-n(commercially available restorative material).
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Decayed Teeth
3D Printed Donor Tooth Replica in Autotransplantation of Teeth
3D printed replicas of the donor tooth can reduce extraoral time during the autotransplantation of teeth, which can reduce dehydration and manipulation of periodontal tissue of the donor tooth, thus possibly increasing the…
- Trial name
- NCT04933409
- Testing
- 3D printed replica of the donor tooth, Conventional Autotransplantation of tooth
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- College of Medical Sciences Teaching Hospital. Nepal
Head and Neck Cancer, Caries, Dental
Post-radiation Dental Disease Amongst Head and Neck Cancer Patients
Background Post-radiotherapy head and neck cancer (HANC) patients are at increased risk of dental caries and periodontal disease due to radiation-related damage to the teeth and salivary glands.
- Conditions
- Head and Neck Cancer, Caries, Dental, Periodontal Diseases, Radiotherapy Side Effect
- Trial name
- NCT03703648
- Testing
- Radiotherapy (curative) for head and neck cancer
- Where
- United Kingdom
- Volunteers
- 215 people
- Sponsor
- Belfast Health and Social Care Trust
Dental Caries in Children
The Impact of Anticipatory Guidance on Early Childhood Caries: a Quasi-experimental Study
This study aimed to compare the impact of anticipatory guidance on the caries incidence of 2-3-year-old preschool children and their 4-6-year-old siblings, as well as on their mothers' oral health literacy, as compared to the…
- Trial name
- NCT03478748
- Testing
- Dental health education
- Where
- Malaysia
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Dental Caries
Clinical Study 3MESPE Crowns CR15/02
This clinical study seeks to address four independent questions that are all part of the delivery of care associated with the provision of a single item of treatment; an indirect restoration (known as a 'crown') to restore and…
- Trial name
- NCT02735304
- Testing
- Impression intervention
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Cavities of Teeth
An Evaluation of Protective Effects of OpalSeal™ Against Early Dental Decay in Orthodontic Patients
Fluoride is very effective in preventing dental decay (cavities) when applied in the form of a varnish on tooth surfaces. The purpose of this study is to verify if fluoride-releasing primer (OpalSeal) offers more protection…
- Trial name
- NCT03722264
- Testing
- OpalSeal, TransbondXT
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Virginia Commonwealth University
Class I Dental Caries
Two-year Clinical Performance of Ion-releasing and Conventional Bulk-fill Resin Composite Restorative Systems.
The goal of this clinical trial is to learn if ion-releasing composite works to induce remineralization in caries-affected dentin in adults.
- Trial name
- NCT07849478
- Testing
- self-cure ion-releasing bulk-fill resin composite, ion-releasing bulk-fill resin composite, conventional bulk-fill resin composite
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
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