Clinical trials: Dental Caries
Dental Caries Class II
Evaluation of Clinical Success of Bulk Fil Composite Versus Highly Viscous Glass Ionomer in Primary Class II Molars
evaluate the clinical performance of EQUIA Forte ® ( a HVGIC) and Plafique® Bulk Flow composite resin when placed in class II cavities in primary molars.
- Trial name
- NCT06235489
- Testing
- Palfique Bulk Flow
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dental Caries
Efficacy Of A PVP-I Fluoride Varnish
The purpose of the study is to determine the efficacy of Advantage Anti-Caries Varnish. Single-center, double-blind, controlled Phase 2 study with parallel groups of children.
- Trial name
- NCT03082196
- Testing
- Test varnish, Standard varnish
- Where
- Micronesia
- Volunteers
- 284 people
- Sponsor
- Advantage Dental Services, LLC
Dental Caries
Effect of Photodynamic Therapy With Low-level Laser on Infected Dentin in Primary Teeth: A Controlled Clinical Trial
The aim of the proposed study is to assess the clinical effect of photodynamic therapy (PDT) on dentin with carious lesions in primary teeth.
- Trial name
- NCT02734420
- Testing
- PapacarieMBlue and PDT, Toluidine Blue O and PDT, Laser
- Where
- Brazil
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Non-carious Cervical Lesions
Clinical Evaluation of Different Universal Adhesive Systems in Non-carious Cervical Lesions.
The aim of the study is to compare the performance of universal adhesives containing different-solvent-based in the restoration of non-carious cervical lesions (NCCLs).
- Trial name
- NCT04707898
- Testing
- Single Bond Universal, G-Premio Bond
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Okan University
Dental Caries
Efficacy and Safety of Primary Teeth Anesthesia Using Nasal Spray in Children
68 healthy children from the Department of Pediatric Dentistry at Damascus University who require treatment for their primary maxillary second molars will be randomly assigned into one of two groups: experimental or control…
- Trial name
- NCT03140787
- Testing
- Nasal Spray of Lidocaine HCL, Infiltration injection of Lidocaine HCL
- Where
- Syria
- Volunteers
- 68 people
- Sponsor
- Damascus University
Dental Caries
Evaluation of Reliability of CarieScan PRO Compared With Digital Radiograph and ICDAS-II in Detection of Carious Lesions
The aim of this study is to evaluate the Clinical performance of alternating current impedance spectroscopy (CarieScan PRO) in comparison with digital radiograph and ICDAS-II in detection of occlusal carious lesions.
- Trial name
- NCT04438252
- Testing
- ICDAS II, CariScan Pro, Digital Radiograpgy
- Where
- Egypt
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Restored Decayed Teeth and Post-operative Sensitivity
Comparative Evaluation of Clinical Success of BIOFLX Crowns and SSC in Primary Molars
Although Stainless steel crowns (SSC) are the gold standard treatment modality for multi-surface carious lesion in paediatric patients, the quest for metal free, aesthetic restoration with comparable features that of SSC still…
- Trial name
- RCT (NCT07465211)
- Testing
- US Public Health Service modified criteria, The parental satisfaction
- Where
- India
- Volunteers
- 36 people
- Sponsor
- satish vishwanathaiah
Dental Caries
Effect of 12 Months Supplementation With a Symbiotic Lozenge on Caries Increment in Healthy Children
The primary objective of this trial is to investigate the effect of a symbiotic lozenge on dental caries in young children.
- Trial name
- PiP-C (NCT03928587)
- Testing
- 2 billion CFU in total of the two strains Lactobacillus paracasei subsp. paracasei and Lactobacillus rhamnosus and arginine.
- Where
- Denmark
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Dental Caries, Oral Bacterial Infection
Ecological Effect of Arginine Dentifrice on Oral Microbiota
caries-free (CF) individuals caries-active (CA) individuals (DMFT ≥ 6) will be recruited. Subjects will be instructed to brush their teeth twice daily for 3 min using Colgate® Sensitive Pro-Relief® toothpaste (containing 8%…
- Conditions
- Dental Caries, Oral Bacterial Infection, Microbiota
- Trial name
- NCT02988349
- Testing
- Colgate® Sensitive Pro-Relief® toothpaste
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sichuan University
Class V Dental Caries
Two Year Clinical Performance of Ion-releasing and Non Ion-releasing Composite Restorative Systems in Restoring Cervical Carious Lesions.
The goal of this clinical trial is to learn if ion releasing composite materials works to induce remineralization of caries affected dentin in adults.
- Trial name
- NCT07849426
- Testing
- Ion-releasing resin composite, Giomer based composite, Non-ion-releasing ormocer based composite
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Black Stain Dental, Dental Black Stain, Black Stain*, Black Stains, Tooth Stains
Assessment of Salivary Bacterial Level and Dental Caries Experience in a Group of Egyptian Children With Black Stained Teeth
Black stains (BS) are type of extrinsic discoloration of the tooth. It's characterized as dark lines or an incomplete coalescence of dark dots found mostly on cervical third of the crown.
- Trial name
- NCT03563469
- Testing
- Salivary bacterial and pH level
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Cairo University
Low Back Pain
Soft Tissue Biomechanical Behavior During Acupuncture in Low Back Pain
The goal of this proposal is to test the overall hypothesis that subjects with chronic or recurrent low back pain have an abnormal soft tissue response to acupuncture needling, and that this altered response is associated with…
- Trial name
- NCT00487266
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Dental Caries
Caries Prevention Effect of S-PRG Filler Incorporated in Denture Base Resins on Edentulous Elderly People
The purpose of this study is to determine whether a novel material of S-PRG fillers containing in a daily-used resin denture base and their capability of fluoride release and recharge to elevate the salivary fluoride level and…
- Trial name
- NCT02460562
- Testing
- S-PRG filler, PMMA resin
- Where
- 3 sites in Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kritirat Kiatsirirote
Dental Caries, Oral Microbial Colonization
Maternal Consumption of Xylitol to Reduce Early Childhood Decay (MaXED Study)
The purpose of this study is to determine if the Childsmile programme (www.child-smile.org) with the additional maternal use of xylitol is more effective at reducing dental decay in children than a Childsmile program alone.
- Trial name
- MaXED (NCT01038479)
- Testing
- Xylitol consumption, Childsmile preventative programme
- Where
- United Kingdom
- Volunteers
- 1,064 people, healthy volunteers welcome
- Sponsor
- NHS Fife
Pulpitis in Permanent Teeth, Dental Caries Extending to Pulp
Pulp Inflammatory Markers and Outcome of Pulpotomy
This is a prospective clinical study that aims to investigate the level of inflammatory mediators in the inflamed dental pulp and its potential relationship to the outcome of full pulpotomy in mature permanent teeth with carious…
- Trial name
- pulpitis (NCT06960603)
- Testing
- Full pulpotomy
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Restoration Failure of Marginal Integrity, Dental Caries
Clinical Investigation of a New Bulk Fill Composite Resin in the Restoration of Posterior Teeth
Polymerization shrinkage remains one of the primary disadvantages of composite resin restorative materials (tooth-colored fillings).
- Conditions
- Dental Restoration Failure of Marginal Integrity, Dental Caries, Unrepairable Overhanging of Dental Restorative Materials, Poor Aesthetics of Existing Restoration
- Trial name
- NCT02572570
- Testing
- Filtek Bulk Fill Posterior, Filtek Supreme Ultra
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Carious Teeth
Comparison of 3D Printed Composite Resin Crowns With Stainless Steel Crowns
The goal of this splith - mouth clinical trial is to compare 3D Printed Prefabric Composite Resin Crowns with Stainless Steel Crowns in healthy 50 children age between 5 and 9 with caries on more than one surface of the primary…
- Trial name
- NCT06161103
- Testing
- 3D Printed Prefabricated Composite Resin Crown Group, Prefabricated stainless steel crown group
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Restoration, Permanent, Dental Caries (Disorder)
Effect of Phosphoric Acid Etching Duration on Direct Resin-Based Composite Restorations in Permanent Anterior Teeth
The goal of this clinical trial is to learn if reducing the phosphoric acid etching (PAE) time affects the performance of direct resin-based composite (RBC) restorations in permanent anterior teeth.
- Conditions
- Dental Restoration, Permanent, Dental Caries (Disorder), Dental Restoration Failure
- Trial name
- ETCH-PRO (NCT06991842)
- Testing
- Permanent dental restoration
- Where
- Switzerland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Florin Eggmann
Decay, Dental
Evaluating the Efficiency of Newly Designed Prefabricated PMMA Crowns for Restoring Primary Teeth in Comparison to Stainless Steel and Zirconia Crowns
Evaluation of PMMA pediatric crowns
- Trial name
- NCT04479046
- Testing
- PMMA crowns
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Dental Caries
Zirconomer-P Versus RMGI for Proximal Restorations in Primary Molars
Clinical trial comparing two tooth-colored restorative materials for treating cavities between the teeth of primary molars in children aged 4 to 7 years.
- Trial name
- NCT07788274
- Testing
- Zirconia-fortified glass ionomer, Resin-modified glass ionomer
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
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