Clinical trials: Dental Caries
Class II Dental Caries
Class II Restoration Using Bioactive Restorative Material vs Polyacid Modified Composite Resin in Primary Molars
Successful restoration of cavities in primary molars can be considered challenging. It is different from restoring cavities in permanent molars because factors such as the level of co-operation of the child and the handling…
- Trial name
- NCT04030117
- Testing
- ACTIVA Bioactive restoration, Compomer restoration
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Oral Health Behavior Change
Assessing the Impact of a Social Media-Based Educational Intervention Using WhatsApp Video Messages on Dental Caries Prevention Knowledge, Oral Hygiene Practices, and Attitudes Toward Dental Health Among Primary School Children Aged 10-12 Years in Public Schools in Cairo Governorate, Egypt: A Quasi-
The goal of this study is to learn if educational videos sent through WhatsApp can improve dental health knowledge, healthy habits, and attitudes in primary school children aged 10 to 12 years in Cairo, Egypt.
- Conditions
- Dental Caries, Oral Health Behavior Change, Oral Hygiene, Oral Health, Knowledge, Attitudes, Practice
- Trial name
- NCT07363317
- Testing
- WhatsApp-Based Dental Health Education for Children
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rana Mohamed Ahmed Farghal
Dental Caries, Periodontal Diseases
Biomimetic Hydroxyapatite in Pediatric Patients With Asthma and/or Allergic Rhinitis
The aim of the study is to compare the incidence of dental caries and the level of demineralization in pediatric patients with asthma and/or allergic rhinitis. Patients will conduct professional oral hygiene at the baseline.
- Trial name
- NCT05631197
- Testing
- Biorepair Total Protection Plus + desensitizing enamel-repair shock treatment, Sensodyne Repair & Protect
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Inflammatory Bowel Diseases, Periodontitis
Oral Health-related Quality of Life (OHRQoL) in Patients With Inflammatory Bowel Disease (IBD)
IBD patients have a higher risk of oral diseases that affect the oral mucosa, the teeth and the tooth supporting tissues. These conditions are often associated with pain, bleeding and impaired masticatory function which may have…
- Conditions
- Inflammatory Bowel Diseases, Periodontitis, Dental Caries, Tooth Loss
- Trial name
- OQal-MICI (NCT05096897)
- Testing
- Self-administrated questionnaires
- Where
- France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Lille
Amelogenesis Imperfecta, Dental Caries
Clinical Performance of Composites in Patients With Amelogenesis Imperfecta
In AI patients, adhesion still remains the first option in order to achieve an early, minimally invasive intervention, and the altered enamel still represents an acceptable substrate for bonding in some AI variants.
- Conditions
- Amelogenesis Imperfecta, Dental Caries, Dental Composite
- Trial name
- NCT04897724
- Testing
- dental composite
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Neslihan Tekçe
Dental Caries
Study on Use of Xylitol-wipes to Prevent Dental Caries
Mutans streptococci (MS) and lactobacillus species (LB) are the two groups of infectious cariogenic (caries-causing) bacteria most strongly associated with dental caries (dental decay).
- Trial name
- WIPE (NCT01468727)
- Testing
- xylitol wipe
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Caries, Dental, Gingivitis
Dental Health Epidemiology Among Israel Defense Forces (IDF) Recruits
An epidemiological survey for prevalence description of dental morbidity (caries, gingivitis, dental trauma and fluorosis) among Israel Defense Forces (IDF) general recruits.
- Conditions
- Caries, Dental, Gingivitis, Fluorosis, Dental Trauma
- Trial name
- NCT02958891
- Testing
- Data collection
- Where
- Israel
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Dental Caries
Comparison of Two GIC's in the Restoration of Posterior Class II Lesions in the Primary Dentition
This study will investigate the clinical performance of a novel restorative glass ionomer (DeltaFil, DMG) in comparison to an established restorative glass ionomer (Riva Self Cure HV, SDI) in the restoration of Class II cavities…
- Trial name
- NCT05965297
- Testing
- DeltaFil, Riva Self Cure HV
- Where
- 2 sites in Brazil, Portugal
- Volunteers
- 140 people
- Sponsor
- DMG Dental Material Gesellschaft mbH
Dental Caries, Tooth Demineralization
"Comparison of the Effects of Resin Infiltrant, Fluoride Varnish, and the Combined Application of Resin Infiltrant and Fluoride Varnish on Primary Molars in the Treatment of Proximal Non-Cavitated Carious Lesions in Children."
Purpose: This randomized controlled clinical trial aimed to compare the effectiveness of fluoride varnish, resin infiltrant, and their combination in treating superficial proximal carious lesions in primary molars of children…
- Conditions
- Dental Caries, Tooth Demineralization, Pediatric Dentistry, Molar, Deciduous
- Trial name
- NCT07112963
- Testing
- Fluoride Varnish
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Sacide Duman
Dental Caries, Gingivitis
Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors
This study is observational only and is intended to evaluate changes in the makeup and function of bacteria naturally present in the mouth during treatment with braces to straighten teeth.
- Trial name
- NCT02885064
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Class 2 Dental Cavity
Comparison of Proximal Contacts and Contours in Class II Composite Restoration With Pre-cured Composite Inserts Versus Contact Making Instrument Technique. A Randomized Control Clinical Trial.
The objective of this randomized control cinical trial will be to compare the effectiveness of precured composite inserts in obtaining tight and adequate conatacts in class 2 restorations when compared with the contact making…
- Trial name
- NCT05386498
- Testing
- precured composite insert technique, Contact making instrument, Incremental composite layering technique
- Volunteers
- 180 people
- Sponsor
- Foundation University Islamabad
Dental Caries
Comparison of the Effect of Fluoride Remineralizer Gel and Foam
Compare the remineralizing effect of acidulated fluoride gel Flugel (1.23% FFA, DFL) and acidulated Fluoride Foam Flúor Care (1.23% FFA, FGM) in maxillary anterior permanent teeth of 58 children aged 7 to 12 years of age.
- Trial name
- NCT02490592
- Testing
- Fluoride Foam, Fluoride gel
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Center of João Pessoa
Carious Lesion, Caries; Initial
Effect of Self-assembly Peptide With or Without Laser on Remineralization of Initial Carious
This study aimed to asses the effect of different remineralizing agents on the initial carious lesions at diff rant after immediately after treatment (as baseline), six months and one year.
- Trial name
- NCT07574814
- Testing
- ER-CR Laser, Without ER-CR Laser
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Delta University for Science and Technology
Dental Caries Class II
Comparison of the 2-year Clinical Performances of Class II Restorations Using Different Restorative Materials
The aim of this study is to compare the clinical success of different filling materials used in the treatment of dental caries. Systemically healthy individuals with good oral hygiene and interproximal caries in their posterior…
- Trial name
- NCT06562868
- Testing
- Bulk-fill Composite Resin, Traditional Posterior Composite Resin, High-filler Flowable Composite
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Dental Plaque, Dental Caries
Evaluation of Oral Plaque Removal Utilizing an Adjunct Enzyme Pre-rinse
This study aims to investigate the impact of a bromelain pre-rinse adjunct on oral plaque removal in orthodontic subjects. The study's null hypothesis states that there is no statistically significant difference in visual plaque…
- Trial name
- NCT04512482
- Testing
- Bromelain, Powdered sugar
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Indiana University
Caries, Dental
Comparing Hall vs Conventional Technique in Placing Preformed Metal Crowns From Sudan
Preformed metal crowns (PMCs) have high success rates in restoring primary molars in children but they were not generally used by dentists, especially in developing countries due to its demand of high clinical skills with the…
- Trial name
- NCT03640013
- Testing
- Hall Technique PMC
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Khartoum Centre for Research and Medical Training
Early Childhood Caries
Oral Health Intervention for Caregivers of Children Presenting for Dental Surgery
Too many young children, particularly those living in poverty, present for dental surgery under anesthesia - an expensive, potentially dangerous, short-term fix that often results in recurring oral health disease and subsequent…
- Trial name
- PROTECT (NCT07220850)
- Testing
- Behavioral Treatment
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- University of Illinois Chicago
Dental Caries
The Behaviour of Dental Nurses Applying Fluoride Varnish to Young Children
The behaviour of 12 dental nurses seeing 600 nursery school children in East Scotland will be video-taped to determine the interaction patterns adopted by the staff in the application of a fluoride varnish to the surfaces of the…
- Trial name
- BEHAVE (NCT00881790)
- Testing
- Fluoride varnish
- Where
- United Kingdom
- Volunteers
- 509 people, healthy volunteers welcome
- Sponsor
- University of St Andrews
Caries, Dental
Clinical Evaluation of ELS Versus ELS Extra Resin Composite
Adhesive restorative materials are routinely used in operative dentistry to improve tooth tissues with minimal preparation, achieve more esthetic and long term restorations.
- Trial name
- NCT03306576
- Testing
- ELS Extra composite, ELS composite
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Medipol University Hospital
Dental Diseases
Intensive Preventative Dental Program Pilot Study
Radiation therapy to treat cancer may cause a dry mouth from damage to salivary glands which may increase the risk of cavities on the teeth.
- Trial name
- IPDP (NCT07218068)
- Testing
- Fluoride varnish, Regular Care, Medical Oncology Care Team
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Wake Forest University Health Sciences
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