Clinical trials: Dental Caries
Oral Diseases
Carnosine Supplementation on Quantity/Quality of Oral Salivae.
The aim of this study is to elucidate the mutual relationship between salivae characteristics and oral microbiome and to compare them with common oral disease; furthermore, by using specific bioinformatic tools to analyse the…
- Trial name
- PHoral (NCT04295525)
- Testing
- 400 mg mucoadhesive oral tablet
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Milan
Caries, Dental
Health Effects of Silver-Mercury Dental Fillings
The purpose of this study is to determine whether there are detectable health effects of low-level mercury exposure (from normal exposure to mercury-containing dental fillings) in the known target organs/systems affected by…
- Trial name
- NCT00066118
- Testing
- Dental amalgam restorations
- Where
- United States
- Volunteers
- 507 people
- Sponsor
- University of Washington
Dental Pulp Cavity, Root Canal Treatment
Endoscopic Treatment During Endodontic Procedures
The objectives of this Phase I study is to evaluate the safety and effectiveness of the endoscopic endodontic equipment device for root canal assistance treatment as well as to evaluate the ease of use of this device, by a…
- Conditions
- Dental Pulp Cavity, Root Canal Treatment, Endoscopy
- Trial name
- NCT01192607
- Testing
- Endoscopic treatment during root canal treatment
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Dental Plaque, Dental Caries
Novamin on Streptococcus Mutans Count in Dental Plaque of High Caries Risk Children
Inhibition of streptococcus mutans can be effective to prevent caries in high caries-risk children. The aim of the study is to evaluate the effect of Novamin on streptococcus mutans in the plaque of high caries-risk children.
- Trial name
- NCT05979636
- Testing
- Novamin containing toothpaste, Fluoride containing toothpaste
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Hams Hamed Abdelrahman
Dental Caries
Comparing Stainless Steel Crowns With Prefabricated Resin Crowns in Primary Molar Teeth
The main reason for this research study is to learn more about a new flexible white dental crown (BioFLX) by comparing it to an existing flexible metal crown (Stainless Steel Crown).
- Trial name
- NCT06713330
- Testing
- BioFLX crown, 3M Stainless Steel Crown
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Dental Caries Extending Into Dentine
Digital Subtraction Radiography Evaluation of SMART Restoration With Partial Caries Removal in Primary Teeth
The objective of this study was to analyze the radiographic density of digital subtraction radiographs after SMART restoration with partial caries removal in primary molars at 6 and 12 months.
- Trial name
- DSR (NCT01749267)
- Testing
- partial caries removal only at enamel dentin junction.
- Where
- Thailand
- Volunteers
- 38 people
- Sponsor
- Mahidol University
Dental Caries Class II
Clinical Success of Single-Color Universal Resin Composites
According to FDI criteria, the success of 4 different universal resin composites was targeted. In our study, a total of 180 teeth will be restored in class 2 cavities with 5 different composite resins in 5 groups.
- Trial name
- NCT06563128
- Testing
- Clearfil Majesty Posterior, Omnichroma Universal Group, Zen Universal Group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Anesthesia
Neurodevelopment Outcomes After Pediatric Dental Caries Treatment Under General Anaesthesia
The purpose of this study is to investigate whether early expose to general anaesthesia will influence neurodevelopment.
- Trial name
- NCT03002792
- Testing
- general anesthesia
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Air Force Military Medical University, China
Dental Caries Class II
Clinical Performance of a Glass-ionomer Restorative System in Extended-sized Cavities
The aim of this clinical trial was to compare the clinical performances of a glass ionomer restorative system with a micro hybrid resin based composite in extended sized class II cavities.
- Trial name
- NCT02991664
- Testing
- Equia Forte, G-aenial Posterior
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries, Bleeding on Probing
Evaluating Methods of Dental Health Instructions on the Oral Health Indices of 12-18-year-old Patients With Fixed Orthodontics
The goal of this clinical trial is to learn which type of oral health education works best to help 12-18-year-old participants with fixed orthodontic appliances (braces) keep their mouths healthy.
- Conditions
- Dental Caries, Bleeding on Probing, Gingival Index, Plaque Index
- Trial name
- NCT07667283
- Testing
- Verbal Oral Hygiene Instruction, Pamphlet-Based Oral Hygiene Instruction, Video-Based Oral Hygiene Instruction
- Where
- Iran
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Dental Caries
Caries Management by Risk Assessment in Children
The goal of this study is to address the effectiveness of a modified cavity prevention protocol for 5-9 year-old children which emphasizes better diet modification, more frequent professional fluoride applications, and xylitol…
- Trial name
- NCT01310283
- Testing
- xylitol mints and fluoride varnish
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pregnancy Related, Oral Health
Self Reported Oral Health, Awareness and Attitude Towards Dental Care Among Pregnant Women
Purpose/Objective of the study: The main objective of the study is to investigate oral health awareness and attitudes towards oral health among Norwegian pregnant women and assess the impact of information about oral hygiene on…
- Conditions
- Pregnancy Related, Oral Health, Attitude, Oxidative Stress
- Trial name
- NCT01675180
- Testing
- Information, Control
- Where
- Norway
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Tromso
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Clinical Investigation of the Performance of Epinamel for Dental White Spot Lesions
Mintech-Bio Ltd is a UK-based start-up company which was created to turn 14 years of research from our co-founder Dr Alvaro Mata at Queen Mary University into a real-world product.
- Trial name
- NCT07730359
- Testing
- Varnish
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Mintech Bio Ltd
Caries Arrested
Selective Versus Stepwise Removal of Deep Carious Lesions in Permanent Teeth Using Different Medicaments
The study involved 54 adult patients between the ages of 18 and 50 years who had a posterior permanent tooth with a deep occlusal (Class I) carious lesion that extended to the inner third of the dentin (D3) and divided them into…
- Trial name
- NCT06585436
- Testing
- partial caries removal
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries, Early Childhood Caries
Preventing Early Childhood Caries in Indigenous Children: the Baby Teeth Talk Study
The purpose of this study is to determine whether a combination of pre- and post-natal preventive and behavioral interventions is effective in preventing early childhood caries in Indigenous children.
- Trial name
- BTT (NCT02151916)
- Testing
- Dental care, AG, MI & fluoride varnish, Delayed intervention
- Where
- Canada
- Volunteers
- 544 people
- Sponsor
- University of Toronto
Dental Caries
The Microbiology of Caries Resistance
The purpose of this research study is to investigate the bacterial composition of plaque and saliva located in the mouth and associate that with risk factors that cause cavities.
- Trial name
- NCT02130206
- Testing
- Caries Free, Caries Active
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Florida
Reduction in DMFT Index and Plaque Index in Patients at the Treatment Completion, an Average of 4 Years, DMFT Index, ICDAS Score, Dental Plaque Index, Communication, Prevention, Dentist, Orthodontist
A New Digital Communication Tool Between Dentist and Orthodontist to Improve Dental Prevention
Dentists and orthodontists of the oral medicine department of Reims University Hospital noted that many children presented white spots around orthodontic brackets, or decays at the end of their multi-brackets orthodontic…
- Trial name
- ComDentODFPrev (NCT06517238)
- Testing
- There is no intervention
- Where
- France
- Volunteers
- 30 people
- Sponsor
- CHU de Reims
Tooth Caries, Dental Plaque
A Comparative Study of the Efficacy in Plaque Removal of Two Manual Toothbrushes
Objective: To compare the efficacy of Curaprox® CS 5460 Ultra Soft and Oral-B® Indicator Plus toothbrushes in dental plaque removal. Methods: 50 adult participants will be included in the sample.
- Trial name
- NCT03502538
- Testing
- Curaprox 5460 Ultra Soft, Oral-B Indicator Plus
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Deep Carious Lesions, Caries Class I
A Comparative Study of Different Traditional and Bioactive Indirect Pulp Capping Materials
The protection of the dentin-pulp complex consists of the application of one or more layers of specific material between the restorative material and dental tissue to avoid additional challenge to the pulp tissue caused by…
- Conditions
- Deep Carious Lesions, Caries Class I, Caries Class II
- Trial name
- NCT06707311
- Testing
- patients received calcium hydroxide with glass ionomer restorative material, patients received TheraCal LC with glass ionomer restorative material, patients received bioactive bonding with glass ionomer restorative material
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Dental Caries
Cinnamon and Ginger in Comparison to Chlorhexidine Gluconate 0.2% on Oral Streptococcus Mutans
Chlorhexidine is the most potent chemotherapeutic agent against mutans streptococci and dental caries, however, the incidence of side effects such as teeth discoloration, staining of restorations, undesirable taste, discoloration…
- Trial name
- NCT03061916
- Testing
- Cinnamon, Ginger, Chlorhexidine Gluconate
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cairo University
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