Clinical trials: Dental Caries
Dental Caries, Quality of Life
Comparative Effectiveness of School-based Caries Prevention
Dental caries (tooth decay) is the most prevalent childhood disease in the world. Multiple interventions are available to treat and prevent caries.
- Trial name
- NCT03442309
- Testing
- Silver Diamine Fluoride, Fluoride Varnishes, Glass Ionomer
- Where
- United States
- Volunteers
- 7,418 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Neurocognitive Deficit, Quality of Life
WHOle Brain Irradiation or STEreotactic Radiosurgery for Five or More Brain Metastases (WHOBI-STER)
This work aims to evaluate neurocognitive performance, daily activity and quality of life and local control among patients with brain metastasis (MBM) ≥ 5 due to solid tumors treated with Stereotactic RadioSurgery (SRS) or Whole…
- Conditions
- Neurocognitive Deficit, Quality of Life, Activities of Daily Living
- Trial name
- WHOBI-STER (NCT04891471)
- Testing
- Stereotactic RadioTherapy, Whole Brain Irradiation
- Where
- 4 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Mediterranean Institute of Oncology
Plaque, Dental, Caries, Dental
Livionex on Reducing Plaque Accumulation and Improving Oral Health in Children
This is an investigator initiated randomized double-blind pilot study at the UCSF Pediatric Dental Clinics to compare effectiveness of a new toothpaste Livionex Dental Gel with a standard children's toothpaste containing 1500 ppm…
- Conditions
- Plaque, Dental, Caries, Dental, Oral Hygiene
- Trial name
- NCT04368533
- Testing
- Livionex Dental Gel, A standard children's toothpaste containing 1500 ppm fluoride
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Carious Teeth
Outcome of Full Pulpotomy Using Calcium Silicate Based Materials
Permanent teeth with carious pulp exposure and indicated for full pulpotomy will be treated using three different materials using aseptic technique and will be subsequently followed up clinically and radiographically at 6 months…
- Trial name
- pulpotomy (NCT04345263)
- Testing
- MTA pulpotomy
- Where
- 2 sites in Jordan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Primary Root Caries
Clinical Effect of Photoactivated Disinfection on Primary Root Carious Lesions After Partial Caries Removal
The problem of root caries has been increasing in last decades as the an average life expectancy is rising. Due to progress of medicine and dentistry humans also maintain natural dentition longer.
- Trial name
- PAD (NCT03186352)
- Testing
- photoactivated disinfection
- Where
- Poland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Type 2 Diabetes, Obesity & Overweight
Effects of GLP-1 Receptor Agonists on Saliva and Oral Health
This study aims to evaluate the effects of GLP-1 receptor agonists (GLP-1RA) on salivary parameters and oral health in individuals who will use this medication for the first time due to a diagnosis of Type 2 diabetes and/or…
- Conditions
- Type 2 Diabetes, Obesity & Overweight, Xerostomia, Dental Caries
- Trial name
- NCT07818226
- Testing
- GLP-1 Receptor Agonists
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kırıkkale University
Cavities of Teeth, Dental Decay
Scotchbond Universal Plus Compared to Scotchbond Universal for Posterior Class I & II Restorations With Filtek Universal
This research study is looking at a new bond-promoting substance (a dental adhesive called 3M™ Scotchbond™ Universal Plus Adhesive) used between the tooth and dental restoration (filling).
- Trial name
- NCT05248204
- Testing
- Scotchbond™ Universal Plus Adhesive, Scotchbond™ Universal Adhesive
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Solventum US LLC
Dental Caries in Children
Pain Assessment During Chemo-Mechanical and Smart Burs Caries Removal Versus Atraumatic Restorative Treatment in Carious Primary Molars
The aim of the clinical trial is to assess pain during Atraumatic Restorative Treatment (ART), Smart Burs and Chemo-mechanical Caries Removal (CMCR) in primary molars.
- Trial name
- NCT05529433
- Testing
- Atraumatic Restorative Treatment (ART), Smart Burs, Chemo-Mechanical Caries Removal (CMCR)
- Volunteers
- 33 people
- Sponsor
- Cairo University
Patient Satisfaction
DPBRN Patient Satisfaction With Dental Restorations
The purpose of this study was to administer two questionnaires. The first, a Dental Satisfaction Questionnaire to assess patient satisfaction with a restoration visit using patients recruited from practices participating in the…
- Trial name
- NCT01201421
- Where
- 7 sites in United States, Denmark
- Volunteers
- 5,932 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Cavities of Teeth
Esthetics of Dental Composite and Adhesive System
To compare a newly developed filling composite to a current filling composite system. Two restorations will be placed in each subject, one using system A and one using system B.
- Trial name
- NCT03716349
- Testing
- Pulp vitality testing, Photos, local and/or topical anesthetic
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Erica Teixeira
Congenital Heart Defect, Dental Caries in Children
Oral Health Intervention Program for Children With Congenital Heart Defects
Background: Children with congenital heart defects (CHD) are reported to have poorer oral health compared with healthy children.
- Conditions
- Congenital Heart Defect, Dental Caries in Children, Dental Erosion, Dental Plaque
- Trial name
- NCT03311438
- Testing
- Oral health intervention program
- Volunteers
- 75 people
- Sponsor
- University of Bergen
Caries, Dental
Alternative Treatment of Deep Carious Lesions Based on Biological Evidences
The purpose of this study is to evaluate the success rate of alternative treatment of deep carious lesions in asymptomatic primary teeth with no clinical nor radiographic signs of pulpal inflammation.
- Trial name
- NCT00973089
- Testing
- Incomplete caries removal in primary teeth
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Caries
Clinical Performance and Wear Resistance of Highly Translucent Nano Zirconia Reinforced Glass Ionomer Filling Versus Conventional Resin Composite Restorations in Patients With Proximal Carious Teeth. (A One-year Randomized Clinical Trial).
This randomized clinical study aims to evaluate the clinical performance and occlusal wear resistance of nano-zirconia reinforced glass ionomer restorations in comparison to Nano-hybrid resin composite in proximal cavities.
- Trial name
- NCT05403008
- Testing
- Zirconomer improved
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
SDF Application in Oral Cancer Patients to Prevent Dental Caries
The Texas A \& M College of Dentistry, with partner Texas Oncology-Baylor Charles A. Sammons Cancer-Center Radiation-Oncology, proposes to conduct a preliminary clinical study (NIH Stage 0) to pilot test a randomized clinical…
- Trial name
- NCT05403125
- Testing
- silver diamine fluoride, 38%, Sodium fluoride gel, 5000 PPM
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Texas A & M University Baylor College Of Dentistry
HIV Infections
Study of Viral Load Decay Rates in HIV Infected Participants Starting Treatment With Raltegravir (RAL) and Emtricitabine/Tenofovir Disoproxil Fumarate (TDF)
The HIV integrase inhibitor, raltegravir (RAL), which was recently approved by the FDA, has been shown in several trials to be highly effective.
- Trial name
- NCT00660972
- Testing
- Raltegravir, Emtricitabine/tenofovir disoproxil fumarate
- Where
- 15 sites in United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Dental Caries, Gingivitis
Parental Perception of Oral Health-Related Quality of Life in Sudanese Refugee vs. Egyptian Children
This cross-sectional analytical study aims to assess and compare parental perceptions of oral health-related quality of life (OHRQoL) among Sudanese refugee children and Egyptian children aged 6-12 years living in Egypt.
- Conditions
- Dental Caries, Gingivitis, Oral Health, Refugee Health
- Trial name
- NCT07011381
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
White Spot Lesion
Effectiveness of Different Remineralizing Strategies on the Management of Early Carious Lesions in Primary Teeth
the primary aim of the study is remineralization of early carious lesions in primary teeth using different remineralizing agents of different remineralizing strategies when applied in an intensive mode.
- Trial name
- NCT06566833
- Testing
- self assmbling peptide p11-4 combined with 0.05% fluoride, Casein phosphopeptide amorphous calcium phosphate, 5% sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Caries, Class I Dental Caries
Effect of Surface Sealant Application on Clinical Performance Occlusal Restorations
The aim was to evaluate the clinical performance of HEMA-containing and HEMA-free all-in-one self-etch adhesives with and without a surface sealing process with a nanohybrid composite in occlusal caries restorations.
- Conditions
- Dental Caries, Class I Dental Caries, Dental Composite
- Trial name
- NCT03184025
- Testing
- dentin adhesive
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Neslihan Tekçe
Dental Caries; Oral Health; Malocclusion
Dental Caries and Related Factors in 6-Year-Old Schoolchildren in Chile: National Evidence for Assessment and Decision-Making (6yOH-Chile)
Dental caries is the most prevalent chronic non-communicable disease in childhood worldwide. In Chile, the last nationally representative oral health survey was conducted in 2007 and reported a caries experience prevalence of…
- Trial name
- 6yOH-Chile (NCT07863947)
- Where
- Chile
- Volunteers
- 2,484 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Dental Caries in Children
Impact of Oral Health Program on Al-Lith Children's KAP
Dental caries remains a significant global public health issue, particularly affecting children's health, development, and well-being, with inadequate knowledge, attitudes, and practices around oral health exacerbating these…
- Trial name
- NCT07009015
- Testing
- The oral health education intervention program
- Where
- Malaysia
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
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