Clinical trials: Dental Caries
Dental Caries in Children
Prevalence of Dental Caries Among a Group of Egyptian Children Using CAST Index
The aim of this study is to assess the prevalence of dental caries using CAST index among a group of Egyptian children in primary dentition stage.
- Trial name
- NCT03573180
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Selective Caries Removal (SCR) Versus Pulpotomy in Preventing Pulp Necrosis and Apical Periodontitis
The study design is a randomized controlled trial and up to 120 teeth, 50 in each of the 2 groups, will be enrolled from the patients at the National University Centre for Oral Health Singapore (NUCOHS) Endodontic unit.
- Trial name
- NCT04672070
- Testing
- Selective Caries Removal, Pulpotomy
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Lumbar Puncture
AI-Assisted Instruction Versus Peer Learning for Sustained Lumbar Puncture Competency
This study compared three teaching methods for training resident physicians in lumbar puncture, a critical medical procedure used to collect spinal fluid for diagnosing conditions like meningitis.
- Trial name
- AI-Assisted (NCT07873073)
- Testing
- Peer Learning
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Root Caries
Assessment of Arresting Root Surface Caries After the Application of PRG Bioactive Varnish
Guidelines proved that arresting and remineralization of the root surface caries is better than weakening the tooth structure and restoring it.
- Trial name
- NCT05509920
- Testing
- S-PRG barrier coat
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Arresting Active Dental Caries in Preschool Children by Topical Fluorides
This randomized clinical trial aims to compare the effectiveness of three topical fluoride application protocols, namely three applications of a 30% SDF solution at yearly or weekly interval and three applications of a 5% NaF…
- Trial name
- NCT02426619
- Testing
- SDF solution, NaF varnish
- Where
- China
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Caries
Effect of Curodont Repair in Patients With Early Approximal Carious Lesions
The purpose of this study is to evaluate the therapeutic benefit of Curodont Repair for the treatment of early approximal carious lesions compared to no treatment.
- Trial name
- NCT02119507
- Testing
- Curodont Repair, No treatment - control
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Credentis AG
Dental Caries
A Phase 2 Study to Evaluate the Microbiology, Safety and Tolerability of C16G2 Varnish and Strip in Adolescent and Adult Subjects
An open-label and single-blind phase 2 study to evaluate the oral microbiology, safety and tolerability of multiple C16G2 Varnish and Strip applications in male and female dental subjects 12-75 years of age.
- Trial name
- C3J17-206-00 (NCT03196219)
- Testing
- C16G2
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Armata Pharmaceuticals, Inc.
Dental Caries (Diagnosis), Diagnostic Imaging
Diagnostic Performance and Children's Acceptance of Near-Infrared Light Transillumination and Bitewing Radiographs for Detecting Proximal Cavitation in Primary Molars of Patients Aged 4 to 10 Years
The goal of this observational study is to compare the diagnostic performance of three detection methods for approximal carious lesions in primary molars among pediatric patients aged 4-10 years.
- Conditions
- Dental Caries (Diagnosis), Diagnostic Imaging, Optical Imaging, Radiographic Image Interpretation, Computer-Assisted
- Trial name
- NILT (NCT07041164)
- Testing
- Bitewing radiograph, Near-infrared light transillumination
- Where
- 2 sites in Thailand
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Sawanya Prutthithaworn
Healthy Participants
The Effect of Daily Brief Heat Exposures on Heat Acclimation
This study is the first to examine the effects of short passive heat exposure on heat acclimation (HA). Unlike traditional protocols requiring prolonged heat exposure, this study tests whether a daily 5-minute whole-body…
- Trial name
- NCT07198334
- Testing
- Heat acclimation
- Where
- Lithuania
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Dental Caries
Ethanolic Extract of Aloe Vera Versus Chlorohexidine as Cavity Disinfectant.
This Randomized Clinical Trial will be conducted to compare the efficacy of ethanolic extract of Aloe vera versus chlorhexidine cavity disinfectant in reducing total bacterial count of Streptococcus mutans (SM) and Lactobacilli…
- Trial name
- NCT04446364
- Testing
- Ethanolic extract of Aloe vera gel cavity disinfectant, Chlorohexadine
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Obesity Prevention
Advancing Water Security: A Community Participatory School-Based Hydration Intervention
The goal of this study is to determine the effectiveness and sustainability of a community-participatory hydration intervention over 3 years within a district that has newly installed hydration stations and is operating under a…
- Trial name
- NCT06714929
- Testing
- Hydration
- Where
- United States
- Volunteers
- 7,200 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Dental Caries, Cervical Caries
The Effectiveness RMGI and Giomer, Individually and Combined Anterior Cervical Caries
This study compares the effectiveness of three dental materials for restoring anterior cervical caries in high-risk patients: resin-modified glass ionomer (RMGI), Giomer, and a combination technique where RMGI is veneered with…
- Trial name
- NCT06901453
- Testing
- Low shrinkage Giomer restorative material (Beautifil II LS), RMGI alone - Control
- Volunteers
- 75 people
- Sponsor
- Cairo University
Dental Caries in Children
Toothbrushing Program in Saudi Arabia "TOPS"
Project summary Introduction: Dental caries is a major oral health problem worldwide and is a particular public health challenge in Saudi Arabia. Dental caries cause pain, infection, and negatively impact quality of life.
- Trial name
- NCT05512156
- Testing
- Supervised Toothbrushing
- Where
- Saudi Arabia
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Head & Neck Cancer, Head & Neck Squamous Cell Carcinoma
Longitudinal Oral Health Changes After Head and Neck Radiotherapy
This prospective observational study evaluates how head and neck radiotherapy affects oral health over time. Patients with head and neck cancer undergoing standard radiotherapy are followed from before treatment through multiple…
- Conditions
- Head & Neck Cancer, Head & Neck Squamous Cell Carcinoma, Periodontal Disease, Xerostomia
- Trial name
- HN-ORAL-RT (NCT07394842)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Helicobacter Pylori Infection
Influence of Oral Hp Infection and Oral Related Factors on Gastric Hp Infection and Eradication Therapy
Helicobacter pylori (H. pylori) is closely related to the occurrence of gastric cancer and other diseases. The discovery and eradication of H. pylori is of great significance for the prevention and treatment of related diseases.
- Trial name
- Hp (NCT05455372)
- Testing
- PPI quadruple therapy
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Pregnancy Related, Dental Caries
The Effects of Pregnancy on Oral Health
The aim of this study was to evaluate the effects of pregnancy on salivary pH, flow rate, caries experience and periodontal status.
- Conditions
- Pregnancy Related, Dental Caries, Periodontal Diseases, Saliva Altered
- Trial name
- NCT06343337
- Testing
- Evaluation of DMFT index, CPI scores, salivary pH and flow rate in pregnant and non-pregnant woman
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Prostate Cancer
Prevention of Micro-architectural Bone Decay in Males With Non-metastatic Prostate Cancer Receiving Androgen Deprivation Therapy (ADT)
Less than 20% of men in whom prostate cancer is diagnosed early die from it. Cardiovascular disease is the most common cause of death in men with early prostate cancer.
- Trial name
- NCT01006395
- Testing
- Zoledronic acid
- Where
- Australia
- Volunteers
- 64 people
- Sponsor
- Austin Health
Chronic Kidney Diseases, Caries,Dental
Assessment of The Oral Health Status of Children With Chronic Kidney Disease
The aim of this study is to compare the oral health findings, salivary parameters and disease-related quality of life of children with different stages of Chronic Kidney Disease(CKD), those undergoing dialysis and…
- Conditions
- Chronic Kidney Diseases, Caries,Dental, Quality of Life, Saliva Altered
- Trial name
- NCT06578832
- Testing
- physical and chemical methods, biochemical methods, biochemical tests
- Where
- Turkey (Türkiye)
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Marmara University
Prevention of Dental Caries
Effectiveness of Different Preventive Regimens in Cariogram Parameters and DMF Scores of High Caries Risk Patients: A Randomized Control Trial
66 Participants will be divided into three groups according to the tested regimen (A), where (A1) represents participants exposed to fluoride toothpaste, (A2) represents participants exposed to regimen including fluoride…
- Trial name
- NCT04032184
- Testing
- Fluoride toothpaste, fluoride toothpaste and chlorhexidine mouthwash, fluoride toothpaste, chlorhexidine mouthwash, MI varnish
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Clinical Performance and Immediate Child and Parental Satis-faction With BioFlx Crowns in Primary Molars: A Prospective, Single-Arm, Non-Randomized Interventional Study
Informed consent was obtained from the parents/guardians of participating children after a detailed explanation about the treatment along with possible outcomes, risks, benefits, and discomforts is provided.
- Trial name
- NCT07471360
- Testing
- Bioflx pediatric dental posterior crowns
- Where
- Saudi Arabia
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
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