Clinical trials: Dental Disease
Dental Caries, Dental Occlusion
Occlusal Impact of Hall Crowns in Primary Molars
Hall Technique is a non-invasive restorative approach for managing carious primary molars, increasingly used in pediatric dentistry due to its simplicity and patient tolerance.
- Conditions
- Dental Caries, Dental Occlusion, Pediatric Dentistry
- Trial name
- NCT07134114
- Testing
- Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Healthy Adult Participants, Tooth Fracture
The Impact of Adhesion Strategy on the Clinical Performance Of Indirect Dental Restorations
The goal of this clinical trial is to evaluate whether different cement systems influence the clinical outcome of posterior tooth supported zirconia crowns in adult patients requiring single crown restorations.
- Trial name
- NCT07644676
- Testing
- Resin cement, Glass-ionomer cement
- Where
- 2 sites in Sweden
- Volunteers
- 110 people
- Sponsor
- Malmö University
Snoring, Apnea, Obstructive
Dental Appliance to Treat SDB in Children
The clinical hypothesis of this study is that a currently marketed mouthguard may also be able to reduce the symptoms of sleep-disordered breathing in children.
- Conditions
- Snoring, Apnea, Obstructive, Upper Airway Resistance Syndrome, Sleep-Disordered Breathing
- Trial name
- NCT05661747
- Testing
- Vivos Grow/Vivos Way Device
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Vivos BioTechnologies, Inc.
Dental Pain
Buffered Local Anesthetic
The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of…
- Trial name
- NCT05757648
- Testing
- Non-buffered Anesthetic, Buffered Anesthetic, Onset
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Disorder of Oral Mucous Membrane
Phase II Clinical Trial of Intraoral Grafting of Human Tissue Engineered Oral Mucosa
The purpose of this study is to improve the current standard of care of repairing mouth soft tissue defects.
- Trial name
- NCT01834326
- Testing
- EVPOME (autogenous ex vivo produced oral mucosa equivalent), POM (Palatal oral mucosa)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Stephen E. Feinberg
Dentinal Hypersensitivity, Dental Pain
The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity
A randomized, controlled, double blind exploratory study to explore the effects of two different potassium nitrate concentrations and water on exposed dentine in reducing dentinal hypersensitivity.
- Trial name
- NCT01587950
- Testing
- Potassium Nitrate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- GlaxoSmithKline
Dental Caries
Therapeutic Effect of Two Fluoride Varnishes on White Spot Lesions: a Clinical Study
The study hypothesis is the difference in therapeutic effect of two varnish formulations (G1 = NaF, 2.26%F, G2 = NaF, 2.71% F + CaF2).
- Trial name
- NCT00723515
- Testing
- sodium fluoride, sodium fluoride calcium fluoride
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Pernambuco
Dental Caries (Disorder)
Color Match Assessment of a Single Shade Structurally Colored Universal Resin Composite
Matching the color of resin composite utilized in anterior teeth is believed to be one of the most challenging tasks a dentist has to face in daily practice.
- Trial name
- NCT04960852
- Testing
- a single shade structurally colored universal resin composite
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- National Research Centre, Egypt
Dental Caries, Tooth Decay
Zirconia-based Primary Anterior Crowns With Retention Grooves Versus Without Retention Grooves
The purpose of this research study is to test the effectiveness of two different crowns/caps on teeth for restoration of primary anterior teeth.
- Trial name
- NCT06354647
- Testing
- Zirconia-based primary anterior crowns with retention grooves, Zirconia-based primary anterior crowns without retention grooves
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Alveolar Bone Loss
Comparison of Extra-short (4 mm) Implants Used as Distal Support of a Maxillary Full-arch Fixed Dental Prosthesis vs. 10 mm Implants Installed After Sinus Floor Elevation.
Recently, 4 mm long implants with a standard diameter have been used for the restoration of the posterior edentulous mandible with favorable results.
- Trial name
- NCT03958448
- Testing
- Placement of extra short implants, maxillary sinus lift, maxillary sinus elevation, maxillary sinus augmentation, placement of standard implant
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Dental Plaque, Dental Prophylaxis
Effectiveness of Customized Handle Toothbrush
People with special needs suffer from many difficulties, including mental, physical or motor, which increase the difficulty of obtaining good oral health.
- Conditions
- Dental Plaque, Dental Prophylaxis, Dental Care
- Trial name
- NCT04845633
- Testing
- Evaluation of the Effectiveness of Conventional Toothbrush in Dental Plaque Control in Healthy Children, Evaluation of the Effectiveness of Customized Handle Toothbrush in Dental Plaque Control in Healthy Children, Evaluation of the Effectiveness of Conventional Toothbrush in Dental Plaque Control in Children with Down Syndrome
- Where
- Syria
- Volunteers
- 48 people
- Sponsor
- Damascus University
Tooth Injuries, Endodontically Treated Teeth
Regenerative Endodontic Treatment of Traumatised Teeth
Aim: The aim of this prospective study was to evaluate the treatment outcomes of regenerative endodontic technique (RET) for the management of traumatised non-vital immature teeth in children.
- Trial name
- NCT03045185
- Testing
- RET using Ciprofloxacin 100mg, and Metronidazole 100mg.
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Behavior, Child, Caries,Dental
Are Dental Neglect and the Siblings Risk Factors in Children
Neglect insidiously affects a child's overall health in all aspects. The aim of this study was to determine whether the presence of siblings caused dental neglect, and whether there was a relationship between dental neglect and…
- Conditions
- Behavior, Child, Caries,Dental, Neglect, Child, Anxiety
- Trial name
- NCT04122508
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Molar Incisor Hypomineralization
Clinical Evaluation of Giomer and Resin-based Fissure Sealants
The objective of this research was to evaluate the clinical success of giomer and resin-based sealants applied in the first permanent molars (FPMs) affected by MIH.
- Trial name
- NCT04929782
- Testing
- Resin-based sealant, Giomer sealants
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Hacettepe University
Missing Teeth
Zirconium Dioxide Fixed Dental Prosthesis.
The purpose of this clinical trial is to evaluate and compare bridges to replace one or two missing teeth in the mouth. The bridges will be made of two variants of ceramic material.
- Trial name
- NCT06352983
- Testing
- Fixed dental prosthesis
- Where
- 2 sites in Sweden
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Malmö University
Gingival Inflammation
Evaluation Of Zirconia Crowns Restoring Endodontically Treated Posterior Teeth With Two Finish Line Designs And Occlusal Reduction Schemes
The aim of this study is to evaluate the clinical performance of two finish line designs (feather edge and rounded shoulder) in relation with two occlusal designs (flat and planar) in endodontically treated teeth restored with…
- Trial name
- NCT04052490
- Testing
- Abutment with flat occlusal reduction with feather edge finish
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Health Related Quality of Life, Oral Disease
Oral Health Related Quality of Life
As oral health has a major impact on general health and quality of life, good oral health are essential. The aspects of oral health that are most important for each individual vary, and quality of life is subjective, and…
- Trial name
- NCT05923762
- Testing
- OHRQoL
- Volunteers
- 3,700 people
- Sponsor
- Dalarna County Council, Sweden
Dental Caries Extending Into Dentin, Root Caries
Root Caries Excavation with Air Water/powder Prophylaxis Device for ART Restorations
The main objective of this RCT is to compare the efficacy of a powder/water jet prophylaxis device and conventional hand excavation in excavating root surface caries, with regard to restoration survival/success in older adults.
- Trial name
- ART-AIRFLOW (NCT04822246)
- Testing
- Control: Hand instrumentation for caries excavation, Intervention 1: EMS Airflow device for caries excavation, Intervention 2: Hand excavation + EMS Airflow device for caries excavation
- Where
- Switzerland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Murali Srinivasan, Dr. med. dent., BDS, MDS, MBA, MAS
Pulpitis - Irreversible
Effect of Preoperative Diclofenac Potassium on Postoperative Endodontic Pain
The purpose of this study is to assess the effect of preoperative a single-dose of 50 mg diclofenac potassium on postoperative endodontic pain in mandibular molars with symptomatic irreversible pulpitis.
- Trial name
- NCT03341260
- Testing
- Diclofenac Potassium 50mg Tab.
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Partial Edentulism
Digital and Conventional Clasp-retained Partial Dentures (DIGICLASP)
This single-center prospective observational cohort study evaluates two fabrication workflows already in routine clinical use for clasp-retained removable partial dentures (RPDs): a digital workflow (Group 1) and a conventional…
- Trial name
- DIGICLASP (NCT07903662)
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Bern
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