Clinical trials: Dental Gingivitis
Gingivitis
Mouthwash of Pomegranate Against Biofilm and Gingival Inflammation in School Children
The mechanical control of supragingival biofilm is accepted as one of the most important measures to prevent dental caries and periodontal diseases. Nevertheless, maintaining dental surfaces biofilm-free is not an easy task.
- Trial name
- NCT02949583
- Testing
- Punica granatum Linn., chlorhexidine
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- Universidade Estadual da Paraiba
Gingival and Periodontal Disease, Caries, Dental
Clinical Evaluation of the Antibacterial Activity of Thioglycosides Extracted from White Mustard - Bamberka in Oral Hygiene. Evaluation of Periodontal Parameters and Oral Microbiota in Patients.
Brief Summary The goal of this randomized clinical trial is to evaluate the clinical and antibacterial effects of a herbal toothpaste containing white mustard (Sinapis alba) extract in patients diagnosed with gingivitis.
- Trial name
- NCT06908265
- Testing
- Toothpaste including mustard extract
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Dental Plaque, Gingivitis
The Clinical Efficacy of Three Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste and a Mouthwash in Controlling Dental Plaque and Gingivitis
The objective of this clinical research study is to assess the efficacy of three oral hygiene multi-component regimens encompassing the use of a manual toothbrush, toothpaste and a mouthwash in controlling established dental…
- Trial name
- NCT02193165
- Testing
- triclosan/fluoride toothpaste + cetylpyridinium chloride Mouthwash, stannous fluoride toothpaste + cetylpyridinium chloride Mouthwash, fluoride toothpaste + fluoride Mouthwash
- Where
- Puerto Rico
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis, Dental Plaque
Pooled Analysis of Clinical Data From Six GSK Studies to Investigate the Efficacy of a Dentifrice Containing 67% Weight by Weight (w/w) Sodium Bicarbonate on Gingivitis and Plaque Accumulation
The aim of this analysis was to pool data from 6 GSK studies with similar clinical design to investigate the overall efficacy of a test dentifrice containing 67% w/w sodium bicarbonate in the treatment of gingivitis and plaque…
- Trial name
- NCT03703245
- Testing
- Sodium bicarbonate, Control Dentifrice
- Where
- United Kingdom
- Volunteers
- 1,601 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Periodontal Diseases, Dental Plaque
Marginal Biofilm Distribution and Periodontal Response to Supragingival and Juxtagingival Aligner Designs
This prospective, longitudinal, within-person (split-mouth) clinical study evaluates the influence of two clear aligner trimming-line designs on marginal soft-tissue biofilm distribution and periodontal tissue response over a…
- Conditions
- Periodontal Diseases, Dental Plaque, Gingivitis
- Trial name
- BIOFILM-ALIGN (NCT07642037)
- Testing
- Supragingival aligner trimming-line, Juxtagingival festooned aligner trimming-line
- Where
- Romania
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Dental Plaque, Gingivitis
Plaque Reduction Sesame Oil
The goal of this clinical trials to learn about potential additives in reducing dental plaque. The main questions it aims to answer is: is there a difference in the plaque reducing effect of oil pulling with sesame oil compared…
- Conditions
- Dental Plaque, Gingivitis, Oral Microbial Colonization
- Trial name
- NCT06327841
- Testing
- sesame oil, distilled water
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University Innsbruck
Dental Plaque
Plaque Removal Efficacy of a U-Shaped Sonic Power Toothbrush in Children
The objective of this single-use, examiner blinded, randomized, two-period, cross-over, IRB-approved clinical study is to evaluate the safety and plaque removal efficacy of AutoBrush®, a new children's 360° sonic toothbrush…
- Trial name
- NCT06300073
- Testing
- Experimental: U-shaped Power Toothbrush
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Lander Enterprises, LLC
Gingivitis, Dental Plaque
Comparing the Efficacy of Toothbrushing With and Without Interproximal Cleaning Aids: A Split-Mouth Trial
The goal of this prospective clinical trial is to evaluate whether adding interproximal cleaning aids (interproximal brush, rubber toothpick, water flosser) to regular tooth brushing improves oral hygiene outcomes and gingival…
- Conditions
- Gingivitis, Dental Plaque, Periodontal Disease
- Trial name
- NCT07725276
- Testing
- Tooth Brushing Alone (Control), Water flosser, Interproximal Brush
- Where
- Lebanon
- Volunteers
- 29 people
- Sponsor
- Saint-Joseph University
Plaque, Dental
Efficacy of a Eugenol-based Product to Improve the Quality of Toothbrushing and Relieving Gum Discomfort Areas
The objective of this study is to evaluate the efficacy of a eugenol-based product in improving the quality of toothbrushing and relieving areas of gingival discomfort.
- Trial name
- NCT06366568
- Testing
- fluoride toothpaste containing 1450 ppm of MFP in a PCC base and eugenol gum product, fluoride toothpaste containing 1450 ppm of MFP in a PCC base
- Where
- Germany
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis, Dental Plaque Accumulation
Study of an Essential Oil and a Delmopinol Mouthrinse Effect on Dental Plaque Accumulation Index, Gingivitis Index and on Streptococcus Mutans, Lactobacillus, Aerobic and Anaerobic Oral Bacteria Colony Counts.
The use of mouthrinses may be of relevance as a complement to daily dental hygiene procedures, especially for patients who do not comply with a proper mechanical removal of dental plaque.
- Trial name
- NCT01236950
- Testing
- Essential oils mouthrinse, Delmopinol mouthrinse
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Gingivitis, Dental Plaque
Comparison Of Clinical Effects Of Listerine And Chlorhexidine Mouth Wash In Patients Undergoing Fixed Orthodontic Treatment
This randomized clinical trial aims to compare the effectiveness of Listerine and Chlorhexidine mouthwashes in improving periodontal health in patients undergoing fixed orthodontic treatment.
- Trial name
- NCT07119840
- Testing
- Listerine Mouthwash Product, Chlorhexidine mouthwash
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Gingiva; Infection, Plaque, Dental
Role of Herbal Dentifrices in the Management of Plaque Induced Gingivitis
The clinical cross over study involves the use of two herbal based dentifirices moringa and miswak and its efficacy in reducing plaque induced gingivitis.
- Trial name
- NCT04830176
- Testing
- dentifrice
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ajman University
Dental Plaque
Clinical Study to Evaluate the Treatment of Gingivitis of Two Toothpastes
The objective is to compare two commerical oral products for the treatment of gingivitis.
- Trial name
- NCT00762515
- Testing
- Fluoride, Triclosan
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Tooth Discoloration, Periodontal Diseases
Evaluating the Efficacy of a Gum Health Formulation on Teeth Whitening in Patients With Gingivitis and Periodontitis
The purpose of this study is to evaluate the efficacy of a novel gum health formulation, when used in an intra-oral device or on a toothbrush, for teeth whitening and clinical improvements in periodontal diseases.
- Trial name
- NCT02906982
- Testing
- Gum health formulation in intra-oral device, Gum health formulation on toothbrush
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Glo Science, Inc.
Dental Plaque and Gingivitis
The Comparative Effects of Using 0.12% Chlorhexidine and Silver Nanoparticles Mouthwashes in Medical Students
This double-blind, randomized intervention study aims to evaluate and compare the efficacy of 0.12% Chlorhexidine (CHX) mouthwash and Nano Silver (AgNPs) mouthwash.
- Trial name
- mouthwash (NCT06963788)
- Testing
- Chlorhexidine 0,12%, 0,9% Chloride Sodium, Silver nanoparticles mouthwash
- Where
- Vietnam
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Tooth Discoloration, Tooth Sensitivity
At-home Bleaching Using Clear Retainers
The aim of this project is to clinically evaluate patient satisfaction, whitening efficacy, tooth sensitivity, and gingival irritation during at-home whitening with 10% carbamide peroxide using an Essix-type retainer or a Vivera…
- Conditions
- Tooth Discoloration, Tooth Sensitivity, Gingivitis, Satisfaction, Patient
- Trial name
- NCT05835453
- Testing
- Whitening
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Gingival Inflammation
The Effect of Instructed Dental Flossing on Interdental Gingival Bleeding: A Randomized Controlled Clinical Trial
In this study, half of the participants will be asked to floss as normal, while the other half will receive professional instructions on flossing from a dentist.
- Trial name
- NCT04218994
- Testing
- Flossing technique
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Tufts University
Elderly, Periodontal Disease
Oral Hygiene Assistance Training Program
This is an oral health study with a nursing home staff training program and product intervention.
- Conditions
- Elderly, Periodontal Disease, Gingivitis, Caries,Dental
- Trial name
- NCT07807397
- Testing
- Stannous Fluoride Toothpaste (SnF), sodium fluoride 5000 ppm, cetylpyridinium chloride (0.075%) and zinc alcohol free mouthwash
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Gingivitis
Comparative Efficacy of Floss and Essential Oil/CPC+Zn Mouthwashes in Reducing Dental Plaque and Gingivitis
The objective of this clinical research study is to evaluate the efficacy of floss to an essential oil alcohol-containing mouthwash, an essential oil alcohol-free mouthwash, and a CPC+Zn alcohol-free mouthwash in reducing dental…
- Trial name
- NCT07029438
- Testing
- Mouthwash, Floss, Toothbrush
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingival Inflammation, Gingival Bleeding
Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem
The primary objective of this clinical study is to evaluate the impact on gingival health when participants switch to a fluoride toothpaste without gum-health actives for 4 weeks after using a proven gum-health toothpaste for 13…
- Conditions
- Gingival Inflammation, Gingival Bleeding, Dental Plaque
- Trial name
- NCT07415733
- Testing
- Test Toothpaste, Control Toothpaste
- Where
- Indonesia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Unilever R&D