Clinical trials: Dental Hygiene
Dental Plaque, Denture Stomatitis
Experimental Denture Pastes
This trial aims to evaluate the efficacy of three experimental dentifrices to remove denture biofilm. Complete denture wearers will be instructed to brush their dentures with a specific toothbrush and four compositions: (1) A…
- Conditions
- Dental Plaque, Denture Stomatitis, Oral Candidiasis, Oral Hygiene
- Trial name
- NCT01237795
- Testing
- Dentifrice
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Raphael Freitas de Souza
Plaque Induced Gingival Disease, Oral Health
Effect of Benzydamine Hydrochloride Mouthrinse on Plaque Accumulation in Periodontally Healthy Female Subjects
The goal of this clinical trial is to evaluate the effect of a mouthrinse containing an active ingredient benzydamine hydrochloride in the absence of daily oral hygiene.
- Trial name
- BHCl-PLAQUE (NCT07565766)
- Testing
- Benzydamine hydrochloride mouthrinse
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Gum Disease, Prediabetes
Improving Oral and Systemic Health in Individuals With Prediabetes Through Personalized Oral Hygiene Advice Provided by Dentists or by AI
Prediabetes is an intermediate stage before the development of diabetes, characterized by elevated blood glucose levels but lower than the diagnostic criteria of diabetes and is associated with multiple long-term complications.
- Trial name
- NCT06980701
- Testing
- AI OHI group, Dental professionals OHI group
- Where
- Hong Kong
- Volunteers
- 148 people
- Sponsor
- The University of Hong Kong
Orthodontic Pathological Resorption of External Root, Complication of Personal Oral Hygiene
Comparison of Oral Hygiene & Root Resorption During Orthodontic Treatment
Orthodontic treatment has been traditionally carried out with fixed appliances involving the use of stainless steel brackets and archwires.
- Trial name
- RCT (NCT02745626)
- Testing
- Appliance
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- UConn Health
Critical Illness
Oral Care to Reduce Mouth and Throat Infections in Critically Ill Patients
This study will evaluate whether a program of systematic oral care can help prevent hospital-acquired respiratory infections in patients in intensive care units.
- Trial name
- NCT00078663
- Testing
- Oral Care
- Where
- 5 sites in United States
- Volunteers
- 800 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Chronic Periodontitis
Clinical and Microbiological Effects of an Essential Oils Solution Used as an Adjunct to Daily Oral Hygiene Practices in Chronic Periodontitis Patients in Supportive Care
Chronic periodontitis is a common infectious disease characterized by progressive attachment loss and alveolar bone resorption eventually resulting in tooth loss.
- Trial name
- Listerine (NCT01195493)
- Testing
- Essential Oils solution, negative control solution
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital, Ghent
Toothbrushing, Dental Plaque
BEhavioral EConomics for Oral Health iNnovation Pilot Trial
This Phase I randomized pilot trial will assess the efficacy of a fixed incentive payment program and drawing incentive payment program versus a control program to promote early childhood caries (ECC) preventive health behaviors…
- Conditions
- Toothbrushing, Dental Plaque, Parent-Child Relations, Oral Hygiene
- Trial name
- BEECON Pilot (NCT03862443)
- Testing
- Fixed Incentive, Drawing Incentive
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Stroke, Aspiration Pneumonia
Effect of Oral Hygiene Care on Prevention of Aspiration Pneumonia Among Hospitalized Stroke Patients
Aspiration pneumonia is a common and serious complication among hospitalized patients with stroke. Poor oral hygiene can increase the risk of aspiration pneumonia by promoting bacterial colonization of the oral cavity.
- Trial name
- OH-STROKE (NCT07382089)
- Testing
- Oral hygiene care bundle
- Where
- Ethiopia
- Volunteers
- 90 people
- Sponsor
- Addis Ababa University
Autism Disorder, Autism Spectrum Disorder (ASD
Effectiveness of Interactive Techniques on Oral Hygiene Skills in a Group of Autistic Egyptian Children
The present study will be performed to evaluate the effectiveness of peer modeling and audiovisual peer modeling video on toothbrushing skills in comparison to the visual pedagogical method at home.
- Conditions
- Autism Disorder, Autism Spectrum Disorder (ASD, Autism, Plaque Reduction
- Trial name
- Autism ASD (NCT07859696)
- Testing
- Peer model, Pre-recorded video of peer modeling, Pedagogical method
- Volunteers
- 90 people
- Sponsor
- Faculty of Dental Medicine for Girls
Dementia, Oral Hygiene
Oral Health, Bite Force and Dementia
Study aims: The primary aim is to identify influencing variables on oral hygiene / oral health and bite force in patients with dementia.
- Conditions
- Dementia, Oral Hygiene, Chewing Problem
- Trial name
- OrBiD (NCT03775772)
- Testing
- Oral Health, Bite Force
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Dental Caries, Dental Plaque
Comparative Effectiveness of Various Educational Approaches on Oral Hygiene
Background: Dental caries constitutes a major global public health challenge, posing substantial burdens on both oral health outcomes and healthcare systems worldwide, with far-reaching implications for prevention, treatment, and…
- Trial name
- NCT06910501
- Testing
- Traditional oral hygiene instruction, Digital slide-based education, Brush DJ mobile appliaction
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ege University
Gingivitis; Chronic
The Effect of Probiotics on Gingivitis: Part 2
The aim of the study is to assess the effect of oral probiotics containing Streptococcus salivarius M18 on gingivitis and oral hygiene in young adults.
- Trial name
- NCT05919134
- Testing
- Dentoblis
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Oral Hygiene
Oral Hygiene in Patients With Orthodontic Fixed Appliances
The study aims to compare the efficacy of the use of different methods of teeth cleaning on the oral hygiene in patients with orthodontic fixed appliance
- Trial name
- NCT03789812
- Testing
- Manual toothbrush, Electric Toothbrush, Superfloss
- Where
- Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Dental Plaque Accumulation, Oral Hygiene in Orthodontic Patients
Comparison of Plaque Removal Efficacy of Different Toothbrushes in Clear Aligner Patients
This study aims to compare the effectiveness of manual and powered toothbrushes in removing dental plaque in patients undergoing clear aligner orthodontic treatment.
- Conditions
- Dental Plaque Accumulation, Oral Hygiene in Orthodontic Patients, Clear Aligner Therapy
- Trial name
- NCT07383636
- Testing
- Manual Toothbrush, Powered Toothbrush
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mersin University
Mild Intellectual Disability
Effect of Virtual Reality Distraction on Perceived Pain During Dental Hygiene in Children With Mild Intellectual Disability: A Randomized Controlled Trial
The objective of this study was to evaluate whether the use of a virtual reality (VR) distractor reduces perceived pain during professional oral hygiene sessions in children with mild ID.
- Trial name
- NCT07473479
- Testing
- Professional oral hygiene session, No distractor
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Oasi Research Institute-IRCCS
Dental Plaque
Livionex Oral Microbiome and Dental Plaque Control in HSCT Recipients
Children undergoing chemotherapy, radiation treatment and Hematopoietic Stem Cell Transplantation (HSCT) have significant difficulties achieving good oral hygiene and dental plaque control.
- Trial name
- NCT02617407
- Testing
- Livionex® Dental Gel, PreviDent 5000 plus/Tom's of Maine Children's toothpaste, Kolibree Toothbrush
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of California, San Francisco
Oral Health
Cluster RCT on the Effect of the Topics Number in Oral Health Educational Video Among Preschool Children.
Purpose: This cluster randomized controlled trials study aims to investigate whether different number of topics delivered through educational video affect the oral health status, knowledge, attitude and practice of preschool…
- Trial name
- NCT06073392
- Testing
- Educational video
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Oral Hygiene, Dental Plaque
Learning Brushing Using Game Elements in Mobile Phones Apps
The study aims to compare the efficacy of using gamification for oral hygiene in children at home environment.
- Conditions
- Oral Hygiene, Dental Plaque, Children, Only, Dental Devices, Home Care
- Trial name
- GAMIFYBRUSH (NCT03935009)
- Testing
- Manual toothbrush Curaprox 5460 ultra soft, Electric toothbrush Play Smart Brush N°1, Electric toothbrush Play Smart Brush N°2
- Where
- 2 sites in Slovenia
- Volunteers
- 100 people
- Sponsor
- University Maribor
Oral Hygiene
A Study to Investigate the Stain and Plaque Removal Capability of Two Experimental Potassium Nitrate Dentifrices
The purpose of this study is to determine whether spherical silica can achieve similar or greater extrinsic dental stain and plaque removal, in comparison to dentifrices containing higher concentrations of standard abrasive…
- Trial name
- NCT03267511
- Testing
- 5% KNO3 / 0.2542% NaF dentifrice with 0.5% spherical silica, 5% KNO3 / 0.2542% NaF dentifrice with 1% spherical silica and 5% STP, 5% KNO3 / 0.2542% NaF dentifrice with 6% abrasive silica
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Non Carious Cervical Lesion, Gingival Recessions
Association Between Periodontal Morphology and Non-Carious Cervical Lesions
This observational study aims to investigate the relationship between periodontal morphology, oral hygiene habits, and non-carious cervical lesions (NCCLs) in adults aged 18-65 years.
- Trial name
- NCCL-PM (NCT07629492)
- Testing
- Periodontal Examination and Oral Habit Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi