Clinical trials: Dental Malocclusion
Malocclusion
One Week Aligner Evaluation
The purpose of this study is to demonstrate that changing aligners weekly provides similar results to changing aligners every two weeks.
- Trial name
- NCT02603289
- Testing
- Invisalign
- Where
- 24 sites in United States, Canada
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Malocclusion
An Electromyography Study Comparing the Impact of Using RMEs on Muscle Activity Among Growing Orthodontic Patients
Compare the impact of using rapid maxillary expanders on masticatory muscle activities (Masseter and Anterior Temporalis muscles) among different posterior cross-bite patient (unilateral, bilateral) as well as compare the…
- Trial name
- NCT02752347
- Testing
- Surface EMG device
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Malocclusion, Angle Class I
Antibiofilm Activity of Chitosan Nanoparticles Incorporated Into Clear Aligners
The use of orthodontic appliances and equipment has dramatically increased over the past few decades, mainly due to improvements in materials and manufacturing processes that have paved the way for improved treatments .
- Trial name
- NCT06823310
- Testing
- Control (Standard treatment), Chitosan
- Where
- Iraq
- Volunteers
- 32 people
- Sponsor
- University of Baghdad
Malocclusion, Cytotoxicity
Evaluate Cytotoxicity, Leaching, and Structural Conformation of Clear Aligners
The aim is to evaluate clear aligners' cytotoxicity, leaching, and structural properties and compare them with four cleaning tools. The null hypothesis is the cleansers have no impact on the properties tested.
- Trial name
- NCT06503029
- Testing
- Invisalign Cleaning Crystals, Fittey Dent Cleaning Tablet, Listeren Mouthwash
- Where
- Saudi Arabia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
CLASS II DIVISION 1 MALOCCLUSION
Pain and Comfort During Functional Orthodontic Treatment With Laser or Ultrasounic Waves
Pain, discomfort, and functional limitations are common during functional orthodontic treatment and may affect appliance acceptance, compliance, and treatment satisfaction.
- Trial name
- NCT07852559
- Testing
- Activator + LIPUS, Activator + LLLT
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Malocclusion, Angle Class II
"Three Dimensional Assessment of Maxillary Molars Following Distalization Using Two Different Approaches"
The goal of this controlled clinical trial is to compare the effects of two distalization methods supported by inter-radicular mini-screw for maxillary molars distalization in 20 adult patients with skeletal class I or moderate…
- Trial name
- NCT06240923
- Testing
- Maxillary molars distalization
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Self-esteem, Personality
Psychological Assessment of Adults Seeking Orthodontic Treatment
Is their a association between the objective and subjective severity of a malocclusion, quality of life and self-esteem/personality (as modifier between objective/subjective severity and quality of life (cfr study Agou et al.…
- Conditions
- Self-esteem, Personality, Quality of Life, Malocclusion
- Trial name
- NCT01475773
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Maxillary Lateral Incisor Malocclusion
Effect of Clear Aligner Attachment Design on Extrusion of Maxillary Lateral Incisors
The purpose of this research is to test which of four clear aligner attachment types is more efficient in extruding (erupting) maxillary lateral incisors vertically into correct position during orthodontic treatment.
- Trial name
- NCT04968353
- Testing
- Incisally-beveled attachment, Gingivally-beveled attachment, Optimized attachment
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Mal Occlusion Class 2
Comparative Study Between Two 3D Functional Appliances Herbst and Mandibular Anterior Repositioning Appliance (MARA) on Posterior Airway Space And TMJ in Growing Class II Malocclusion Patients
The aim of this study is to evaluate effect of three dimensional printed appliances Herbst appliance and Mandibular Anterior Repositioning Appliance (MARA) on Posterior Airway Space (PAS) and Temporomandibular Joint (TMJ) in…
- Trial name
- NCT07094841
- Testing
- 3D PRINTED herbst appliance, 3d printed mara
- Volunteers
- 20 people
- Sponsor
- Moataz Sleem Ahmed Ali
Class II Malocclusion, IMPA Angle
Comparing the Impact of Rubber Bands on Teeth Straightening with Clear Aligners Versus Traditional Braces: a Clinical Study
Aim: To analyze the inclination of lower incisors in patients with Class II malocclusion treated with elastics and clear aligners compared to a group wearing the same elastics and fixed appliance.
- Trial name
- Class II (NCT06832475)
- Testing
- clear aligners and elastics, class 2 elastics
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Rome Tor Vergata
Class II Malocclusion, Division 1
Evaluation of 3D Printed Modified Twin Block for Correction of Skeletal Class II Malocclusion in Growing Females
The study is to evaluate the effect of 3D printed modified Twin Block Appliance on skeletal Class II profile correction. The null hypothesis of this research is that use of 3D Printed Twin Block is not able to induce skeletal…
- Trial name
- NCT04028661
- Testing
- 3D printed Modified Twin Block Appliance
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Crowding, Tooth
Dental and Periodontal Changes Following the Acceleration of Alignment of Crowded Lower Anterior Teeth Using a Surgical Technique
Patients at the Orthodontic Department of the University of Damascus Dental School will be examined and subjects who meet the inclusion criteria will be included.
- Trial name
- NCT05390320
- Testing
- PAOO, Fixed appliance
- Where
- Syria
- Volunteers
- 38 people
- Sponsor
- Damascus University
Malocclusion, Tooth Movement
Additional Palatal Force in Maxillary Canine Distalization
In orthodontic treatment involving extraction of the maxillary first premolars, the canine is distalized into the extraction space using sliding mechanics.
- Trial name
- NCT07862790
- Testing
- Combined buccal and palatal distalizing force, Buccal distalizing force
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Atlas University
Dental Malocclusion, Stability
Retention With Three Different Bonded Retainers a Multicenter, Randomized Controlled Trial With 5-year Follow-up
One of major challenges in orthodontics is to inhibit relapse and ensure stability of treatment outcomes. Retention is the phase of orthodontic treatment that attempts to keep teeth in the corrected position after correction with…
- Trial name
- NCT04828096
- Testing
- Orthodontic retention
- Where
- 2 sites in Spain, Sweden
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Malocclusion, Angle Class I, Crowding
The Role of Low Level Laser Therapy in Acceleration of Teeth Alignment in Lingual Orthodontic Patients
We will treat patients with class I malocclusion who have moderate crowding (4-6 mm) according to Little's irregularity index and asses the efficacy of low level laser therapy in accelerating orthodontic tooth movement .
- Trial name
- NCT03646942
- Testing
- low level laser therapy, Lingual Orthodontics
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Mandibular Fractures
Focused Registry to Collect Clinical Data on the MatrixWAVE System
The goal of this registry is to evaluate the performance of the MatrixWAVE(TM) MMF system in patients suffering from non-condylar and/or condylar fractures.
- Trial name
- MatrixWAVE (NCT03405389)
- Testing
- MatrixWAVE MMF System
- Where
- 2 sites in United States, Germany
- Volunteers
- 44 people
- Sponsor
- AO Innovation Translation Center
CLASS II DIVISION 1 MALOCCLUSION
Comparative Effect of Clear Aligner Mandibular Advancement and Twin Block Appliances in Class II Malocclusion
The goal of this retrospective observational study is to compare the effects of Clear Aligner Mandibular Advancement (MA) and Twin Block (TB) appliances in treating Class II malocclusion, a condition where the lower jaw is…
- Trial name
- NCT06609733
- Testing
- Twin block, Clear aligner with mandibular function
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Sichuan University
Dental Malocclusion, Edentulous Mouth
Safety and Technical Performance of Plastalgin and Plastalgin Fast in Patients Requiring a Dental Impression
The aim of this study is to gather clinical data related to the use of Plastalgin and Plastalgin Fast, in order to comply with the new medical device regulation.
- Conditions
- Dental Malocclusion, Edentulous Mouth, Dental Misalignment
- Trial name
- NCT05614635
- Testing
- Plastalgin and Plastalgin Fast
- Where
- 2 sites in France
- Volunteers
- 59 people
- Sponsor
- Septodont
Class II Malocclusion
Conventional Versus 3D Printed Twin Block Appliances in Growth Modification of Class II Malocclusion
The present study was conducted to evaluate the outcomes of conventionl versus 3D printed twin block appliances in growth modification of class II malocclusion (comparative clinical study) in both groups.
- Trial name
- RCT (NCT07792525)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion
Effect of AcceleDent® Aura on Orthodontic Tooth Movement With Aligners
The purpose of this study is to examine the amount of tooth movement achieved over time between subjects undergoing aligner treatment using a pulsation device known as AcceleDent® Aura with those not using the device.
- Trial name
- NCT01962012
- Testing
- AcceleDent Aura
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- OrthoAccel Technologies Inc.