Clinical trials: Dental Malocclusion
Palatal Expansion Technique, Malocclusion
Comparison Between Two Rates of Activation of Miniscrew-Supported Upper Jaw Expander in Adolescents
Miniscrew-supported maxillary expanders provide advantages over conventional tooth-supported expanders. However, there is no consensus in the literature regarding their activation protocol.
- Conditions
- Palatal Expansion Technique, Malocclusion, Posterior Crossbite, Maxillary Hypoplasia
- Trial name
- NCT04225637
- Testing
- Miniscrew-Supported Maxillary Expander- Slow activation, Miniscrew-Supported Maxillary Expander- Rapid activation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Open Bite
Early Treatment of Anterior Open Bite Using the Rapid Molar Intruder
This study evaluated the efficacy of rapid molar intruder (RMI) in treating anterior open bite in the mixed dentition. The study sample consisted of 40 patients who had a skeletal anterior open bite.
- Trial name
- NCT05657522
- Testing
- Rapid molar intruder
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Angle Class I
Effect of Systemic Administration of Vitamin D on the Rate of Orthodontic Tooth Movement - A Randomized Control Trial
This study is to evaluate the effect of vitamin D on the rate of tooth movement by measuring and comparing the extraction space closure during retraction in experimental (vitamin D supplemented) and control groups with a sample…
- Trial name
- NCT05202496
- Testing
- Calcitriol 0.25Mcg Cap, orthodontic treatment
- Where
- India
- Volunteers
- 24 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Malocclusion, Crossbite
Evaluation of Removable Appliances and Clear Aligners in Early Orthodontic Treatments During the Mixed Dentition Period
This prospective study aims to compare two different orthodontic treatment modalities-clear aligners and removable appliances-in children aged 6 to 12 years during the mixed dentition period.
- Trial name
- NCT07331090
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Neslihan Atmaca
Malocclusion, Abnormalities, Jaw
Personalized Titanium Plates vs CAD/CAM Surgical Splints in Maxillary Repositioning of Orthognathic Surgery
The purpose of this study is to determine whether personalized titanium plates can achieve better accuracy than CAD/CAM surgical splint in maxilla repositioning in orthognathic surgery, and evaluate the feasibility of this…
- Trial name
- NCT02914431
- Testing
- 3D Printing Personalized Titanium Plate
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Class II Division 1 Malocclusion
Activator vs the EF Class II Standard in the Treatment of Severe Overjet in Angle Class II Division 1 Malocclusion
Objective: The purpose of this study was to compare the clinical effectiveness of reducing severe overjet in Angle Class II division 1 malocclusion between Activator and the EF (Functional Education) class II standard in…
- Trial name
- NCT06566027
- Testing
- Skeletal, dental, soft tissue index changes in Activator group
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Malocclusions, Malocclusion, Angle Class I
Microanalysis of Changes in 3D Geometry of Orthodontic Mini-implants
The orthodontic mini-implants used in the study are temporary screws inserted into the bone to provide anchorage for challenging tooth movements that could not be carried out using the patient's own teeth.
- Conditions
- Malocclusions, Malocclusion, Angle Class I, Malocclusion, Angle Class II
- Trial name
- NCT06743360
- Testing
- Insertion, Scanning
- Where
- 2 sites in Poland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Malocclusion
Nano-Crystalline Ceramic Coating of Orthodontic Archwires
Purpose: The project aims to assess if hard ceramic coatings on orthodontic archwires will reduce the sliding resistance of archwires in the brackets during orthodontic treatment procedures.
- Trial name
- NCT02311491
- Testing
- Ceramic coated orthodontic archwire
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Class II Division 1 Malocclusion
The Effect of Autologous Platelet Concentrations on Orthodontic Treatment Time
60 patients needed therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines were divided to randomly three groups: (1) PRP group: Received PRP injections, (2) I-PRF group…
- Trial name
- NCT05335824
- Testing
- The platelet-rich plasma (PRP), The injectable platelet-rich fibrin (I-PRF) group, The control group
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Malocclusion, Crowded Teeth
Evaluation of the Levels of Pain and Discomfort Between Two Methods of Correcting Misaligned Teeth
Applying flapless piezocision corticotomies on the alveolar bone and separating anterior mandibular teeth using a piezosurgery device (i.e.
- Conditions
- Malocclusion, Crowded Teeth, Surgical Incision
- Trial name
- NCT02975765
- Testing
- Piezosurgery
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Malocclusion, Angle Class I, Malocclusion, Angle Class II
3D Printed Occlusal Splints for Intraoperative Use
A 3D printed intraoperative occlusal splint is a custom-made biocompatible resin guide that allows surgeons properly align a patient's upper and lower dentition during surgery.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- NCT07079111
- Testing
- Formlabs 3D printed occlusal splint, Industry made occlusal splint
- Volunteers
- 70 people
- Sponsor
- Johns Hopkins University
Class II Malocclusion
Effect of Upper Third Molar Extraction on Distalization Carriere Motion Appliance :A Prospective Clinical Study
This clinical study will be directed to compare the effect of presence or absence of third molar on distalization of the upper posterior segment by using carriere motion appliance
- Trial name
- NCT05166928
- Testing
- carriere motion appliance
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Cross Bite
Evaluation Of Different Rapid Orthodontic Expansion Devices
Evaluating and comparing the short term effects of different palatal expanders on the amount of palatal expansion and buccal tipping of posterior teeth.
- Trial name
- NCT03258411
- Testing
- Rapid Expansion of palatal suture
- Where
- Saudi Arabia
- Volunteers
- 31 people
- Sponsor
- King Abdulaziz University
Malocclusion, Tooth Movement Techniques
Efficacy of Orthodontic Tooth Movement Using Beveled and Conventional Attachments in Aligners
The objective of this study is to evaluate the efficacy of tooth movement using beveled attachments and conventional attachments.
- Trial name
- NCT06873932
- Testing
- Arm 1: Beveled Attachments, Conventional Rectangular Attachments
- Where
- Brazil
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Neodent
Class II Div 2 Incisal Relationship
Comparison Between 2 Protocols for the Treatment of Class II Division 2 Malocclusion
The aim of this prospective study was to compare between two different treatment modalities of class II division 2; to start treatment in upper arch first until adequate overjet is obtained or to start in the lower arch first…
- Trial name
- NCT03833739
- Testing
- Fixed appliance
- Where
- Jordan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Malocclusion
Comparison of Acupressure, Ibuprofen, and Chewing Gum for the Management of Post-Archwire Orthodontic Pain
The goal of this clinical trial is to find out which method works best to reduce pain after braces are adjusted for the first time (when the first archwire is placed).
- Trial name
- NCT07638644
- Testing
- Acupressure, Ibuprofen 400 mg (if necessary), Chewing Gum
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Bahria University
Crossbite, Malocclusion
Rapid Maxillary Expansion with Low Level Laser Therapy
The posterior crossbite is a common type of malocclusion that might affect the normal growth pattern. Early treatment is recommended by rapid maxillary expansion with different appliances.
- Conditions
- Crossbite, Malocclusion, Cross Bite, Maxillary Constriction
- Trial name
- NCT05586997
- Testing
- Bonded-Hyrax, Bonded Rapid Maxillary Expansion and low-Level Laser therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Research Centre, Egypt
Malocclusion, Angle Class II
Myofunctional Therapy Twin Block
There are situations where orthodontic treatment cannot provide long-term benefits. The proposed orthotropic theory proposes that environmental factors cause malocclusion and genes decide its pattern.
- Trial name
- twin block (NCT05227469)
- Testing
- myofunctional therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Orthodontic Treatment, Tooth Crowding
Assessment of the Efficacy of the Aerodentis System
The purpose of this study is to evaluate the efficacy of the Aerodentis System for orthodontic tooth movement in an open label, two-arms, non-inferiority clinical study.
- Conditions
- Orthodontic Treatment, Tooth Crowding, Orthodontics
- Trial name
- NCT03421886
- Testing
- Aerodentis system, Invisalign clear aligner system
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Malocclusion; Displaced Teeth
Can Magnification Loupes Make the Bracket Bonding Procedure Faster and More Comfortable?
This study aims to evaluate whether using 3.5x dental magnification loupes improves the speed and patient comfort of the orthodontic bracket placement procedure in patients with crowded dentition, a condition that can make the…
- Trial name
- NCT07474389
- Testing
- Loupes-based bonding, Traditional bonding
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University