Clinical trials: Dental Malocclusion
Malocclusion, Tooth Movement
Additional Palatal Force in Maxillary Canine Distalization
In orthodontic treatment involving extraction of the maxillary first premolars, the canine is distalized into the extraction space using sliding mechanics.
- Trial name
- NCT07862790
- Testing
- Combined buccal and palatal distalizing force, Buccal distalizing force
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Atlas University
Cross Bite, Malocclusion
Impact of Anterior Cross Bite Treatment on Children's Speech Performance
The goal of this prospective, single-arm clinical trial is to evaluate the speech performance of children with anterior dental crossbite before and after correction.
- Conditions
- Cross Bite, Malocclusion, Speech, Quality of Life
- Trial name
- NCT06168695
- Testing
- removable anterior expansion screw, Speech and language evaluation, Oral Health Related Quality of Life (OHRQoL) Assessment
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Abnormalities, Jaw, Malocclusion, Angle Class III
First-In-Man Performance and Safety Evaluation of the CARLO® Device in Midface Osteotomies
The study product is a Cold Ablation Robot-guided Laser Osteotome (CARLO®) robotic surgery device. It is a device that removes hard tissue such as bone by means laser ablation - it is therefore an alternative to Piezo-Electric…
- Trial name
- NCT03901209
- Testing
- Mid-face osteotomy
- Where
- 4 sites in Austria, Germany and 1 more
- Volunteers
- 31 people
- Sponsor
- Advanced Osteotomy Tools (AOT) AG
Class III Malocclusion
Mandibular Sequential Distalization Versus Class III Elastics With Clear Aligners in Class III Patients
Distalizing mandibular molars may be indicated for patients with minor skeletal Class III discrepancies or in Class III subjects with mild crowding.
- Trial name
- NCT06859606
- Testing
- Lower molar distalization, Class III elastics
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Saint Camillus International University of Health Sciences
Malocclusion
The Use of Clear Aligners With Movement Enhancement Techniques
The purpose of this study is to use clear aligners to measure tooth movement and length of treatment.
- Trial name
- NCT02087163
- Testing
- Movement Enhancement Technique, Clear Aligner
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Cleft Lip and Palate
Clinical Effectiveness of Late Maxillary Protraction for Cleft Lip and Palate
Patients with cleft lip and palate frequently develop Class III (Cl III) malocclusions or underbites following early cleft repair surgeries.
- Trial name
- PROTRACTSURG (NCT02789787)
- Testing
- Maxillary Protraction, Orthognathic Surgery
- Where
- 2 sites in United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Malocclusion, Angle Class II
Vertical Effects in Class II Patients Treated With Distalization
Class II malocclusion presents a major and common challenge to orthodontists. Treatment of Class II malocclusion is one of the most investigated and controversial issues in contemporary orthodontics because of the extensive…
- Trial name
- NCT05298280
- Testing
- Pendulum appliance, clear aligners
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Rome Tor Vergata
Malocclusion
Effect of VPro5 Therapy on Clear Aligner Therapy
The investigators hypothesize that brief, daily application of HFA will increase the efficiency of clear aligner treatment by altering PDL metabolism without increasing pain or discomfort.
- Trial name
- NCT03240770
- Testing
- VPro5 device, Deviation from Standard Tray Wear Time (14 Days)
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mani Alikhani
Skeletal Class III Malocclusion
Comparison of Ertty Gap III and Facemask Therapy for Skeletal Class III Correction
This single-center, parallel-group randomized clinical trial compared 2 orthopedic treatment approaches in growing patients with skeletal Class III malocclusion associated predominantly with maxillary deficiency: the Ertty Gap…
- Trial name
- NCT07771660
- Testing
- Ertty Gap III Appliance, Facemask Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara University
Malocclusion, Angle Class II, Tooth Movement Techniques
Palatal Guide Wire for Canine Control During Miniscrew-Supported Distalization
When crowded or protruded teeth are treated by removing an upper premolar on each side, the canine (eye tooth) is first moved backward into the space.
- Trial name
- PGWCanine (NCT07845227)
- Testing
- Palatal guide wire, Miniscrew-supported canine distalization
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Atlas University
TMD/Orofacial Pain, Malocclusions
Evaluation of the Effects of Orthognathic Surgeries on the Temporomandibular Joint Using a Mandibular Movement Analyzer Device
Condylar position and mandibular motion assessment with digital facebows Arcus Digma III before and after orthognathic surgery.
- Trial name
- NCT07828041
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Semmelweis University
Malocclusion Class I, Crowding of Teeth
Self-ligating vs Conventional Brackets and Labial Bone Thickness During Crowding Correction in Adults
This randomized clinical trial compares two types of orthodontic brackets, self-ligating and conventional, in adults aged 18 to 25 with moderate crowding of the lower front teeth (4 to 8 mm).
- Trial name
- NCT07878234
- Testing
- Self-ligating orthodontic brackets, Conventional orthodontic brackets
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Future University in Egypt
Malocclusion
"Facially Driven Digital Full-Mouth Rehabilitation"
Participants with bite difficulties, smile dissatisfaction, and missing mandibular molars was rehabilitated using a fully digital, facially driven workflow.
- Trial name
- NCT07314034
- Testing
- Facially Driven, Fully Digital Full-Mouth Rehabilitation with Guided Implant Placement, TAD-Assisted Molar Intrusion, and Restorative Crowns/Veneers
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Menoufia University
Class I Malocclusion
Assessment of Treatment Efficacy Using Smile Arc Marginal Ridge Approach Versus MBT Chart Method for Bracket Positioning
The goal of this randomized clinical trial is to evaluate the effect of Smile Arc Marginal Ridge Approach (SAMRA) versus MBT chart method for bracket positioning on orthodontic treatment results.
- Trial name
- NCT06652230
- Testing
- Smile Arc Marginal Ridge Approach (SAMRA), MBT Chart Method
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maxillary Retrognathism, Children
Treatment of Mandibular Overjet in Children With Maxillary Retrognathism
The project involves a 10-year prospective longitudinal cohort multicentre study where orthodontic treatment and treatment effect is followed in children with Cl III due to maxillary retrognathia who undergo standardized…
- Conditions
- Maxillary Retrognathism, Children, Treatment, Class III Malocclusion
- Trial name
- NCT07706400
- Testing
- Interceptive treatment
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Malmö University
Temporomandibular Joint Dysfunction Syndrome, Tooth Injuries
Effectiveness of Three Oral Devices as Mouthguard in Electroconvulsive Therapy. Randomized Crossover Clinical Trial.
This observer-blind crossover intervention study aims to determine the most effective type of device as oral mouthguard in modified-Electroconvulsive Therapy (m-ECT) comparing three types of devices: standard, prefabricated and…
- Conditions
- Temporomandibular Joint Dysfunction Syndrome, Tooth Injuries, Dental Occlusion, Traumatic
- Trial name
- NCT02678715
- Testing
- Solubrux®, Customized Appliance, Somatics®
- Where
- Spain
- Volunteers
- 4 people
- Sponsor
- Eva Willaert Jiménez-Pajarero
Malocclusion of Anterior Teeth
Clinical Evaluation of Zirconium Dioxide Nano-Coated Arch Wires
"This clinical trial aims to evaluate the clinical performance and efficiency of zirconium dioxide nano-coated orthodontic archwires compared to conventional archwires.
- Trial name
- NCT07813117
- Testing
- Zirconium dioxide nano-coated archwire, Conventional orthodontic archwire
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Malocclusion, Open Bite
Anterior Open Bite Treatment With Bonded Spurs Associated With Build-ups Versus Conventional Bonded Spurs
This study compares the dentoalveolar and skeletal effects of bonded spurs associated with build-ups versus conventional bonded spurs in the early treatment of anterior open bite patients.
- Trial name
- NCT03702881
- Testing
- Bonded Spurs associated with posterior build-ups, Conventional bonded spurs
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Class II Division 1 Malocclusion
Comparison Between Mini Implant Supported Appliance and Headgear in Treatment of Maxillary Excess in Growing Patients
The aim of the study is to compare an Infra-zygomatic Mini implant supported appliance with headgear in distalization and intrusion of maxillary dentition for treatment of growing patients with class II malocclusion (maxillary…
- Trial name
- NCT03839303
- Testing
- Infra-zygomatic Mini Implant Supported Appliance, high pull head gear
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malocclusion, Angle Class III
Treatment of Class III Malocclusion Using Modified Fixed Mandibular Retractor Appliance
This experimental study aims to evaluate the efficiency of the Modified Fixed Mandibular Retractor Appliance in the treatment of skeletal class III malocclusion.
- Trial name
- NCT03354442
- Testing
- Modified Fixed Mandibular Retractor Appliance
- Where
- Syria
- Volunteers
- 44 people
- Sponsor
- Damascus University