Clinical trials: Dental Malocclusion
Class II Malocclusion
Comparative Effect of Conventional and 3D-printed Twin Block Appliances on Soft Tissue Changes
: To evaluate the effectiveness of functional device treatment using both 3D-printed and conventional Twin Block appliances on soft tissue changes during growth modification in Class II malocclusion.
- Trial name
- Clinic Radiogr (NCT07795138)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion of Anterior Teeth
Effects of Laser Therapy and Vitamin D Pills on Braces Tooth Movement: A Random Controlled Study
This clinical trial aims to evaluate the efficacy of low-level laser therapy (LLLT) in conjunction with oral vitamin D3 supplementation in accelerating orthodontic tooth movement in adults with crowded mandibular anterior teeth…
- Trial name
- LLLT (NCT07286474)
- Testing
- Cholecalciferol (Vit D3), Low-Level Laser Therapy, Fixed Orthodontic Appliance
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Tooth Crowding
Effect of Corticotomy on the Orthodontic Tooth Movement
Orthodontic therapy allows for the treatment of dental malpositions in order to produce an adequate relationship between teeth during occlusion. Conventional orthodontic therapy applies slight forces and moves teeth slowly.
- Trial name
- NCT01630473
- Testing
- Corticotomy, Conventional orthodontics
- Where
- Colombia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Malocclusion, Canine Retraction
Comparing Ligation Methods During Canine Retraction Stage Using Conventional Brackets
The goal of this Randomized Controlled Trial (RCT) is to determine the most effective way to tie the main wire to the regular orthodontic brackets during the stage of orthodontic treatment where the canines are retracted.
- Trial name
- NCT07063186
- Testing
- Group A - Elastomeric power chain on all bracket wings., Group B - Stainless steel ligatures with elastomeric power chain placed over all bracket wings., Group C - Elastomeric modules on mesial wings and power chain on distal wings.
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- International Islamic University Malaysia
Class III Malocclusion, Hyoid Bone
The Effect of Orthopedic Face Mask Use on Head Posture and Pharyngeal Airway
The aim of this study was to evaluate the changes in head posture, position of the hyoid bone, pharyngeal airway and cervical posture after the use of Petit type face mask in patients with skeletal class III malocclusion (ANB…
- Trial name
- NCT05114642
- Testing
- Skeletal Class III Malocclusion Treatment with Face Mask Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Taner OZTURK, DDS, MS
Malocclusion, Malocclusion; Displaced or Missing Teeth
Effectiveness of Auxiliary Segmental Lingual Appliances in Leveling the Curve of Wilson at Second Molars
This study aims to evaluate the effectiveness of auxiliary segmental lingual appliances in leveling the Curve of Wilson at the second molars in patients undergoing labial fixed orthodontic treatment.
- Conditions
- Malocclusion, Malocclusion; Displaced or Missing Teeth, Malocclusions, Orthodontic Treatment
- Trial name
- EASLALCW (NCT06858670)
- Testing
- Auxiliary Segmental Lingual Appliances
- Where
- Vietnam
- Sponsor
- Hanoi Medical University
Class II Malocclusion, Mandibular Deficiency
Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II
Objective: to evaluate the dentoskeletal effects of CAD/CAM 3D-Printed fixed twin block versus MARA appliances in the management of skeletal class II due to Mandibular Deficiency in Preadolescence Class II malocclusion is…
- Trial name
- NCT07340242
- Testing
- MARA appliance, fixed twin block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Class II Division 1 Malocclusion
Measuring Rate of Anteriors Retraction With Two Different Techniques
Few studies had investigated the effectiveness of segmental retraction. As a result of that, this study was concerned about comparing retraction rate of maxillary incisors between buccal and palatal mini-implant supported…
- Trial name
- NCT05542745
- Testing
- palatal and buccal retraction
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Crowding, Tooth
Patient-centered Outcomes During Using Self-ligating Brackets With or Without Piezocision vs Traditional Brackets
The different types of brackets (e.g., self-ligating and conventional brackets), and the various acceleration methods (e.g., corticotomy) cause varying degrees of pain and discomfort.
- Trial name
- NCT05416242
- Testing
- Traditional braces, Self-ligating braces, Self-ligating braces + piezocision
- Where
- Syria
- Volunteers
- 63 people
- Sponsor
- Damascus University
Malocclusion of Anterior Teeth
Evaluation of Self-ligating Brackets Plus Minor Surgery in Treating Crowded Cases of Malocclusion
Patients at the Orthodontic Department of University of Damascus Dental School will be examined and subjects who meet the inclusion criteria will be admitted then the initial diagnostic records (diagnostic gypsum samples …
- Trial name
- NCT03647241
- Testing
- Self-Ligating Brackets, Traditionally-Ligated Brackets, Corticotomy
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Malocclusion
Class II Correction Study Using the Invisalign System
To demonstrate that growing teenagers which present up to full cusp Class II malocclusions can be treated using the Invisalign System.
- Trial name
- NCT02376829
- Testing
- Invisalign System
- Where
- 10 sites in United States, Canada
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Class II Div 1 Malocclusion, Protrusion, Incisor
Effectiveness of Two Corticotomy Techniques in Retracting the Upper Anterior Teeth by Using Miniscrews
This study aims to evaluate and compare the skeletal, dental and soft tissue changes, the levels of pain and discomfort and the effect on periodontal health and teeth vitality associated to traditional corticotomy and flapless…
- Trial name
- NCT03279042
- Testing
- Flapless corticotomy surgical intervention will be conducted, Traditional corticotomy
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Malocclusion
OrthoPulse™ and Its Effect on the Rate of Orthodontic Tooth Alignment: A Pilot Feasibility Study
The aim of this study is to determine the effect of OrthoPulse™, an intra-oral LED (Light Emitting Diode) photobiomodulation device, on the rate of anterior orthodontic alignment.
- Trial name
- NCT02267837
- Testing
- OrthoPulse™
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Biolux Research Holdings, Inc.
Class II Malocclusion, Class II Malocclusion, Division 1
Distalization With Aligners: Anchorage Options
Background: To compare the dentoskeletal effects of Class II elastic anchorage and infrazygomatic crest (IZC) miniscrew anchorage in sequential maxillary molar distalization using clear aligners.
- Trial name
- NCT06631131
- Testing
- Distalization with clear aligners supported by Class II elastics, Distalization with clear aligners supported by miniscrew
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Bezmialem Vakif University
Skeletal Class II Malocclusion, Skeletal Class III Malocclusion
Clinical and Radiographic Evaluation of Low Sagittal Medial Ramus Osteotomy for Treatment of Skeletal Class II and Class III Malocclusion
This prospective clinical trial aims to evaluate the clinical and radiographic outcomes of the low sagittal medial ramus osteotomy-a technical modification of the conventional sagittal split osteotomy (SSO)-for treating patients…
- Conditions
- Skeletal Class II Malocclusion, Skeletal Class III Malocclusion, Dentofacial Deformities
- Trial name
- NCT07746700
- Testing
- Low Sagittal Medial Ramus Osteotomy
- Volunteers
- 11 people
- Sponsor
- Al-Azhar University
Maxillary Transverse Deficiency Class I Malocclusion Vitamin D Deficiency Orthodontic Tooth Movement Adolescent Health
Effect of Serum Vitamin D on MARPE Treatment Response
A total of 30 patients are planned to be included in the study during the first half of 2025, who will apply to the clinic. In our clinical routine, approximately 30% of RME patients are treated using the MARPE method.
- Trial name
- NCT06943443
- Testing
- Miniscrew-Assisted Rapid Palatal Expansion (MARPE) Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Class II Malocclusion
Which is Better Piezosurgery or LLLT in Accelerating Orthodontic Tooth Movement
Sixty patients requiring extraction-based treatment of the maxillary first premolars, followed by retraction of the maxillary canines, will be randomly assigned to three groups: piezocision, low-level laser therapy, and control.
- Trial name
- NCT05227859
- Testing
- Piezocision, Low-level laser, Conventional treatment
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Malocclusion
Oral Functions and Malocclusions
The aim of our research is to establish a link between malocclusions and oral dysfunctions. The clinical examination includes: caries screening (DMFT and dft scores), a quantification of dental plaque (Silness and Loë's plaque…
- Trial name
- MALODYS (NCT04869839)
- Testing
- oral examination
- Where
- France
- Volunteers
- 359 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Class I Malocclusion, Class II Div 1 Malocclusion
Assesment of Ethnic Bias in an Artificial Intelligence Based Orthodontic Diagnosis System
This study explores how artificial intelligence (AI) can be used in orthodontics, which is the area of dentistry that focuses on correcting jaw and bite problems.
- Conditions
- Class I Malocclusion, Class II Div 1 Malocclusion, Class II Division 2 Malocclusion, Class III Malocclusion
- Trial name
- NCT07162753
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Malocclusion, Orthodontic Appliance Complication
Microbiological and Epithelial Evaluation Related to the Use of Orthodontic Thermoplastic Device
Thermoplastic devices are used in orthodontic treatment and consists of a series of nearly invisible, removable aligners. However, every device used in the mouth can change the buccal flora and increase the number of bacterias.
- Trial name
- NCT02427763
- Testing
- hours of use (Essix), collect saliva, collect biofilm
- Where
- Brazil
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Universidade Positivo