Clinical trials: Dental Malocclusion
Class II Division 1 Malocclusion, Retrognathic Mandible
Fixed Lingual Mandibular Growth Modificator
The current trial was designed to investigate the possible initial net skeletal and dental effects of treatment with FLMGM by a comparative evaluation of treated and untreated Cl II/1 malocclusion subjects.
- Trial name
- FLMGM (NCT01853137)
- Testing
- Fixed Lingual Mandibular Growth Modificator (FLMGM)
- Where
- Syria
- Volunteers
- 43 people
- Sponsor
- Damascus University
Orthodontic Treatment, Tooth Crowding
Assessment of the Efficacy of the Aerodentis System
The purpose of this study is to evaluate the efficacy of the Aerodentis System for orthodontic tooth movement in an open label, two-arms, non-inferiority clinical study.
- Conditions
- Orthodontic Treatment, Tooth Crowding, Orthodontics
- Trial name
- NCT03421886
- Testing
- Aerodentis system, Invisalign clear aligner system
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Malocclusion
Class II Correction Study Using the Invisalign System
To demonstrate that growing teenagers which present up to full cusp Class II malocclusions can be treated using the Invisalign System.
- Trial name
- NCT02376829
- Testing
- Invisalign System
- Where
- 10 sites in United States, Canada
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Malocclusion
Accelerated Invisalign Therapy in Conjunction With Acceledent Aura
Purpose: The objective of this study is to investigate the effects of accelerated Invisalign and vibration therapy on rate of orthodontic tooth movement, activation of inflammation biomarkers as well as pain levels experienced by…
- Trial name
- NCT02868554
- Testing
- AcceleDent Aura, Accelerated Invisalign therapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of North Carolina, Chapel Hill
Malocclusion
Clinical Performance of a New Esthetic, Self-ligating Orthodontic Bracket
A cohort of 15 patients starting orthodontic treatment with fixed appliances will receive EXD-952 Ceramic Self-ligating brackets on all mandibular incisors and a different type of brackets on the remaining mandibular teeth.
- Trial name
- NCT02959671
- Testing
- Lower Anterior EXD-952 Self-ligating Brackets
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Minnesota
Malocclusion
Evaluation of a "Flash-free" Adhesive Resin for Orthodontic Bracket Bonding
The purpose of this study is to compare bonding time, bond survival, amount of adhesive remaining on the tooth surface after bracket debonding, and time required for adhesive remnant cleanup between a new "flash-free" and a…
- Trial name
- NCT02030002
- Testing
- APC Flash-Free Adhesive Coated Appliance System, APC II Adhesive Coated Appliance System
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Dental Malocclusion, Angle Class II
BRIUS Vs FFA Efficiency
The purpose of this study is to compare the Full Fixed Preadjusted appliances (regular braces) when to the BRIUS system.
- Conditions
- Dental Malocclusion, Angle Class II, Angle Class I, Crowding, Tooth
- Trial name
- NCT04347018
- Testing
- BRIUS
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Malocclusion
Alveolar Microperforation for Inflammation-Enhanced Tooth Movement During Orthodontic Treatment
The purpose of this research study is to assess the clinical effectiveness of the procedure of a minimally invasive alveolar microperforation procedure to achieve accelerated tooth movement in patients undergoing orthodontic…
- Trial name
- Propel (NCT01720797)
- Testing
- Micro-osteoperforation, Anesthestic, Chlorhexidine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Florida
Maxillary Lateral Incisor Malocclusion
Effect of Clear Aligner Attachment Design on Extrusion of Maxillary Lateral Incisors
The purpose of this research is to test which of four clear aligner attachment types is more efficient in extruding (erupting) maxillary lateral incisors vertically into correct position during orthodontic treatment.
- Trial name
- NCT04968353
- Testing
- Incisally-beveled attachment, Gingivally-beveled attachment, Optimized attachment
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Malocclusion
OrthoPulse™ and Its Effect on the Rate of Orthodontic Tooth Alignment: A Pilot Feasibility Study
The aim of this study is to determine the effect of OrthoPulse™, an intra-oral LED (Light Emitting Diode) photobiomodulation device, on the rate of anterior orthodontic alignment.
- Trial name
- NCT02267837
- Testing
- OrthoPulse™
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion
Micro-osteoperforations and Tooth Movement
The purpose of this study is determine the effect the Microosteoperforation (MOPs) using the miniscrew on the rate tooth movement.
- Trial name
- NCT02473471
- Testing
- Micro-osteoperforation
- Where
- Jordan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Malocclusion, Class II Buccal Segment Relationship
Chesterfield Micro-implant Study Involving Three Types of Anchorage Methods in Orthodontics
Research problem: Anchorage reinforcement is effective with headgear provided patient compliance is optimal. Nance palatal arch have also been shown to be effective.
- Trial name
- PJSPhD (NCT00995436)
- Testing
- Extraoral anchorage, Miniscrews, Nance
- Where
- United Kingdom
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Chesterfield and North Derbyshire Royal Hospital
Malocclusion
The Use of Clear Aligners With Movement Enhancement Techniques
The purpose of this study is to use clear aligners to measure tooth movement and length of treatment.
- Trial name
- NCT02087163
- Testing
- Movement Enhancement Technique, Clear Aligner
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Malocclusion
The Effect of Ultrasound on Orthodontic Tooth Movement
To study whether or not the Aevo System™ medical device enhances the rate of tooth movement in human subjects who use orthodontic braces.
- Trial name
- NCT01828164
- Testing
- Ultrasound
- Where
- 5 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SmileSonica Inc.
Dental Malocclusion
Precision Orthodontics: A Comparison of Custom vs Traditional Bracket Treatment Efficiency
This investigational testing aims to target multiple investigations sites to examine treatment efficiency metrics using a completely digital and patient-specific bracket treatment system for the correction of malocclusions.
- Trial name
- NCT04266769
- Testing
- LightForce Orthodontic System
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- LightForce Orthodontics
Malocclusion
Evaluation of Clear Aligner Trays to Straighten Teeth
The objective of this study is to evaluate the efficacy of Clear Aligners to correct tooth malocclusions with the use of attachments and/or buttons, as determined by the amount of teeth movement and overall achievement goals of…
- Trial name
- NCT03141788
- Testing
- Clear Aligner
- Where
- 9 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Solventum Orthodontics Corporation
Malocclusion, Angle Class I
A Comparison Between GUMMETAL and SS Orthodontic Wires in Space Closure
When there is space present between our teeth orthodontically we have the ability to close them through many methods. Using braces as our treatment modality this study will be investigating how efficient a new orthodontic wire is…
- Trial name
- NCT04591080
- Testing
- GUMMETAL Orthodontic Wire, Stainless Steel (CrNi)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Malocclusion
The Effect of OrthoPulse™ on the Rate of Orthodontic Tooth Movement
This open label study is designed to evaluate the ability of OrthoPulse™ to safely and effectively increase the rate of orthodontic tooth movement with fixed appliances.
- Trial name
- BX8RN (NCT02267811)
- Testing
- Orthodontic Treatment, OrthoPulse™
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Biolux Research Holdings, Inc.
Peripheral Nerve Facial Nerve Paralysis, Facial Nerve Diseases
Study of a New Technique to Improve the Symptoms of Orofacial Discomfort in Patients With Peripheral Facial Paralysis
The purpose of this study was to evaluate the effects of Neuro Occlusal Rehabilitation (RNO) in patients with peripheral facial palsy (PFP) disease, noting the decrease in symptoms of masticatory dysfunction.
- Conditions
- Peripheral Nerve Facial Nerve Paralysis, Facial Nerve Diseases, Orofacial Pain
- Trial name
- NCT01327157
- Testing
- occlusal adjustment., Visual analog scale.
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Federal University of São Paulo
Malocclusion
Primer Aligner Study
To demonstrate that a primer aligner product can achieve similar results to the currently marketed product.
- Trial name
- NCT02550938
- Testing
- Invisalign
- Where
- 19 sites in United States, United Kingdom
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.