Clinical trials: Dental Occlusion
Congenital Diaphragmatic Hernia, Pulmonary Hypoplasia
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia (FETO)
The purpose of this research is to gather information on the safety and effectiveness of a new procedure called Fetoscopic Endoluminal Tracheal Occlusion (FETO).
- Conditions
- Congenital Diaphragmatic Hernia, Pulmonary Hypoplasia, Pulmonary Artery Hypertension
- Trial name
- FETO (NCT03138863)
- Testing
- BALT GoldbBAL2 Detachable Balloon, Catheter System
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Rodrigo Ruano
Stroke, Acute
Stent Retriever Versus Contact Aspiration in Irregular Occlusion Phenotype
Patients with a clinico-neuroradiological mismatch pattern shown on the magnetic resonance imaging/Computed Tomography in the acute phase of stroke are more likely to benefit from reperfusion, are suitable candidates for…
- Trial name
- STRIPE (NCT05595876)
- Testing
- stent retriever thrombectomy, contact aspiration thrombectomy
- Where
- 9 sites in France
- Volunteers
- 356 people
- Sponsor
- Hopital Foch
Pulpitis
Comparative Evaluation of Pulpal Anaesthetic Efficacy of Different Anaesthetic Solutions for Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis
Pulpal and periapical inflammation and infection can cause tissue pH in the affected region to be lowered which results in less penetration of anesthetic solution in the nerve membrane and hence delays the onset of anesthesia.
- Trial name
- NCT05239078
- Testing
- local anaesthetic injection
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dr. Vivek Aggarwal
Permeable Foramen Ovale, Cerebrovascular Accident
Interest of Occlusion of Permeable Foramen Ovale After a Cryptogenic Cerebrovascular Accident (CVA)
Facing the lack of recommandations of Neurology and cardiology societies, the investigators decided in 2002 some Good Medical Practices to define a specific and precise population for whom the closure of permeable oval formaen…
- Trial name
- FOPasa (NCT00872443)
- Testing
- Data collection
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Nantes University Hospital
Symptomatic Irreversible Pulpitis
Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars
Introduction: to evaluate the efficacy of inferior alveolar nerve block (IANB), Gow-Gates nerve block (GGNB), and their combination in patients with irreversible pulpitis.
- Trial name
- NCT03117491
- Testing
- GGNB injections, IANB injections, GGNB + IANB injections
- Where
- Iran
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Atrial Fibrillation
Contribution of Image Fusion in Percutaneous Left Atrial Occlusion procédures (Fusion Image)
Atrial fibrillation is the most common rhythm disorder, affecting 2 to 3 percent of the population. One of the major complications is the occurrence of thromboembolic events, the thromboembolic risk can be predicted by the…
- Trial name
- NCT03961490
- Testing
- No interventional study
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Nantes University Hospital
Hepatic Vein Thromboses, Hepatic Venous Outflow Obstruction
Global Coagulation Assessment in Portal Vein Thrombosis and Budd-Chiari Syndrome
Portal vein thrombosis is defined as partial or complete occlusion of the portal vein lumen by the blood clot or its replacement by multiple collateral vessels with the hepato-petal flow, known as 'portal cavernoma'.
- Conditions
- Hepatic Vein Thromboses, Hepatic Venous Outflow Obstruction, Portal Vein Thrombosis, Portal Hypertension, Noncirrhotic
- Trial name
- Liv-Thrombus (NCT05123326)
- Testing
- Rotational thromboelastometry, Genetic tests for Thrombophilia, ELISA tests/ Functional assays
- Where
- India
- Volunteers
- 300 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Hemodynamic Instability, General Anesthesia
End-eXpiratory Occlusion Test to Predict fluId REsponsiveness in the Operating Room (EXPIRE)
The purpose of the study is to evaluate the influence of different durations of the end-expiratory occlusion test to predict fluid responsiveness in mechanically ventilated patients in the operating room.
- Conditions
- Hemodynamic Instability, General Anesthesia, Surgery, Protective Mechanical Ventilation
- Trial name
- EXPIRE (NCT04399278)
- Testing
- Diagnostic Test: end-expiratory occlusion (EEO) test
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Fissure Sealants, Oral Hygiene Orientation
Efficacy of Sealants in Cavitated Enamel Lesions on Occlusal Surfaces in Children
The aim of this study is to evaluate the efficacy of oral hygiene orientation singly, compared to resin-based sealants in controlling occlusal cavitated enamel lesions on primary and permanent molars.
- Trial name
- SLM1661 (NCT02617940)
- Testing
- fissure sealant, oral hygiene orientation
- Where
- Brazil
- Volunteers
- 546 people
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Vascular Aneurysm, Vascular Occlusive Disease
LeMaitre® CARDIAL Dialine II Post Market Study
This clinical study will capture clinical data specific to the performance and safety of the LeMaitre® CARDIAL Dialine II. It is a retrospective, monocenter, post-market safety and performance study.
- Conditions
- Vascular Aneurysm, Vascular Occlusive Disease, Artery Injury
- Trial name
- Dialine II® (NCT05350358)
- Testing
- LeMaitre Cardial Dialine II
- Where
- France
- Volunteers
- 262 people
- Sponsor
- Geprovas
ARDS (Acute Respiratory Distress Syndrome)
Free for Weaning ECMO vs Respiratory Driven Study
In its most severe form, Acute Respiratory Distress Syndrome (ARDS) may require the use of veno-venous ECMO (vvECMO). While the criteria for vvECMO indication, ECMO settings, and ventilator management are relatively well-defined…
- Trial name
- FORWARD (NCT06876415)
- Testing
- P0.1 and delta Poeso integration into the decanulation decision
- Where
- 4 sites in France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Coronary Artery Occlusion
Neuroaxial Prophylaxis for CABG
Investigators plan to study the effect of thoracic epidural analgesia on postoperative parameters (complication rate, duration of hospitalization, mortality, etc.) of coronary artery bypass grafting.
- Trial name
- NCT04244435
- Testing
- CABG, thoracic epidural analgesia, analgesia of opioids
- Where
- Russia
- Volunteers
- 300 people
- Sponsor
- Volgograd State Medical University
Coronary Total Occlusion
Long-term Clinical Follow-up After PCI for CTO
The research aimed to evaluate the impact of a successful Percutaneous coronary intervention of chronic total occlusions (CTO-PCI) on long-term MACE (Major Cardiovascular Events), symptoms, survival, Left Ventricular Ejection…
- Trial name
- LT-CTO (NCT06544174)
- Testing
- Percutaneous Coronary Intervention of CTO
- Where
- France
- Volunteers
- 448 people
- Sponsor
- University Hospital, Montpellier
Dental Caries, Non-cavitated Occlusal Caries
Detection of Non-cavitated Occlusal Caries Lesions by Visual Inspection, LF, QLF and NILT
This study aims to evaluate and compare the diagnostic accuracy of visual examination using ICDAS-II and three adjunctive optical methods-laser fluorescence (LF), near-infrared light transillumination (NILT), and quantitative…
- Trial name
- NCT07532291
- Testing
- Diagnostic assessment of occlusal caries
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Neslihan Atmaca
Intensive Care Units, Ultrasonography
End-expiratory Occlusion Test and Prediction of Preload Dependence
Three sets of measurements of hemodynamic parameters and sub-aortic VTI were performed: before and at the end of 15 seconds end-expiratory occlusion and after 250 mL saline administration over 10 minutes.
- Conditions
- Intensive Care Units, Ultrasonography, Blood Volume
- Trial name
- NCT05874531
- Testing
- End-expiratory occlusion test
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- Mongi Slim Hospital
Acute Ischemic Stroke
Rescue Distal Thrombectomy in Treatment for Persistent Distal Occlusions
The goal of this clinical trial is to determine whether rescue distal mechanical thrombectomy can improve outcomes in patients with persistent distal occlusions after successful proximal mechanical thrombectomy for acute ischemic…
- Trial name
- 2BE3-PhaseII (NCT07533253)
- Testing
- Proximal mechanical thrombectomy, Rescue distal mechanical thrombectomy, Conservative management
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Femoral Arterial Stenosis, Stenosis of Popliteal Arteries
LEVANT Japan Clinical Trial
To demonstrate the safety and efficacy of MD02-LDCB for treatment of stenosis or occlusion of the femoral and popliteal arteries in the Japanese population.
- Conditions
- Femoral Arterial Stenosis, Stenosis of Popliteal Arteries, Femoral Artery Occlusion, Occlusion of Popliteal Arteries
- Trial name
- NCT01816412
- Testing
- MD02-LDCB Paclitaxel coated balloon catheter, Standard Uncoated Balloon Angioplasty Catheter
- Where
- Japan
- Volunteers
- 110 people
- Sponsor
- C. R. Bard
Respiratory Failure
EX-PO Trial : Evaluation of the Occlusion Pressure (PO.1) in Extubation Failure
Measuring bedside occlusion pressure in neurosurgical or surgical critically ill patients could tell us about the patient's respiratory drive, and therefore, tell us whether or not extubation will be successful.
- Trial name
- NCT04654273
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Poitiers University Hospital
Retinal Vein Occlusion, Macular Edema
Bevacizumab Versus Ranibizumab in Treatment of Macular Edema From Vein Occlusion
Antagonists of the vascular endothelial growth factor (VEGF) pathway are effective in treating macular edema resulting from retinal vein occlusion (RVO).
- Trial name
- CRAVE (NCT01428388)
- Testing
- Intravitreal injection of bevacizumab, Intravitreal injection of ranibizumab (0.5 mg per dose)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Barnes Retina Institute
Large Vessel Occlusion
Evaluation of Heuron CTA for Detecting Suspected Large Vessel Occlusion Using Brain CT Angiography
This study evaluates Heuron CTA, a software that helps doctors detect blockages in brain blood vessels using CT angiography images.
- Trial name
- NCT07546019
- Testing
- Heuron CTA
- Where
- South Korea
- Volunteers
- 270 people
- Sponsor
- Heuron Inc.
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