Clinical trials: Dental Occlusion
Stroke Prevention, Atrial Fibrillation
Stand-alone Totally Thoracoscopic Left Atrial Appendage Occlusion Using AtriClip® Device in Non-valvular Atrial Fibrillation.
Polish multicenter registry to assess safety and durability of totally thoracoscopic left atrial appendage occlusion for stroke prevention in atrial fibrillation.
- Conditions
- Stroke Prevention, Atrial Fibrillation, Safety Issues
- Trial name
- THORACS-LAAO (NCT03838341)
- Testing
- AtriClip™ LAA Exclusion System, Oral anticoagulation therapy
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Left Atrial Appendage Closure
Intracardiac Versus Transesophageal Echocardiographic Guidance for Left Atrial Appendage Occlusion
This single-center, prospective, randomized study will evaluate the safety and feasibility of Intracardiac echocardiography (ICE)-guided Left atrial appendage closure (LAAC) when compared to the traditional Transesophageal…
- Trial name
- ICETEE (NCT06348394)
- Testing
- Intracardiac Echocardiography, Traditional transesophageal echocardiography
- Where
- United States
- Volunteers
- 444 people
- Sponsor
- Baylor Research Institute
Neovascular Age-Related Macular Degeneration (nAMD), Diabetic Macular Edema
Speculum-Free Intravitreal Injection Using Cotton-Tipped Applicator Retraction: Pain, Procedure Time, Patient Satisfaction, and Safety
This randomized controlled trial compares two techniques for eyelid retraction during intravitreal injection (IVI): an adjustable solid-blade eyelid speculum (Group A) and single-hand retraction of the upper eyelid with one…
- Conditions
- Neovascular Age-Related Macular Degeneration (nAMD), Diabetic Macular Edema, Retinal Vein Occlusion, Intravitreal Injections
- Trial name
- IVI-RETRACT (NCT07481500)
- Testing
- Eyelid Speculum Retraction, Cotton-Tipped Applicator Retraction
- Where
- Thailand
- Volunteers
- 129 people
- Sponsor
- Jakkrit Juhong
Coronary Artery Disease Obliterative, Chronic Total Occlusion (CTO)
A Prospective, Non-Randomized Pivotal Clinical Investigation to Demonstrate the Safety and Performance of the TrueCross Single-Use Microcatheter
The trial is a pivotal clinical investigation, which is a prospective, non-randomized pivotal clinical investigation to demonstrate the safety and performance of the TrueCross Single-use Microcatheter.
- Trial name
- NCT06030271
- Testing
- Microcatheter
- Where
- 7 sites in Georgia, Greece and 1 more
- Volunteers
- 60 people
- Sponsor
- Insight Lifetech Co., Ltd.
Dental Caries
DPBRN Longitudinal Study of Questionable Occlusal Caries Lesions
The purpose of this study will allow us to observe and follow the subjects' treatment from DPBRN Prevalence of Questionable Occlusal Caries Lesions Study over a 24 month period.
- Trial name
- NCT01309971
- Where
- 7 sites in United States, Denmark
- Volunteers
- 2,624 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Age Related Macular Degeneration, Diabetic Macular Edema
Cytokine and Visual Outcome Variations in Eyes Receiving Ranibizumab
Objective: To determine the association between baseline aqueous cytokine levels and treatment intervals for patients under a variable dosing regimen with intravitreal ranibizumab in patients with neovascular age-related macular…
- Conditions
- Age Related Macular Degeneration, Diabetic Macular Edema, Macular Edema, Retinal Vein Occlusion
- Trial name
- COVERT (NCT03056092)
- Testing
- Intravitreal ranibizumab
- Where
- 2 sites in Canada
- Volunteers
- 168 people
- Sponsor
- Unity Health Toronto
Retinal Vein Occlusion
Ultra-wide-field Fluorescein Angiography in Patients With Retinal Vein Occlusion
The changes of ischemic index and vascular leakage index, and the effect on macular edema and neovascularization in retinal vein occlusion by ultra-wide field fluorescence angiography (UWFA)
- Trial name
- UWFARVO (NCT04075695)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Renmin Hospital of Wuhan University
Healthy
Comparison of Two Devices Using Near-infra Red Spectroscopy During a Vascular Occlusion Test
Tissue oxygen saturation is non-invasively measured using near-infrared spectroscopy, by two device, INVOS®(somanetics Corporation, USA ) and InSpectra™ (Hutchinson Technology, USA).
- Trial name
- NCT01848977
- Testing
- vascular occlusion test
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Chronic Total Occlusion
Antiplatelet Therapy After Successful Percutaneous Coronary Intervention for Chronically Occluded Coronary Artery
Coronary arteries are in charge of oxygen supply for the myocardium. When coronary arteries develop stenosis the coronary blood flow (i.e. oxygen flow) is reduced.
- Trial name
- DAPT-CTO (NCT06175377)
- Testing
- Percutaneous coronary intervention, Short dual Aspirin/Clopidogrel therapy, Long dual Aspirin/Clopidogrel therapy
- Volunteers
- 660 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Branch Retinal Vein Occlusion, Retinal Blood Flow
Assessment of Retinal Vessel Diameters and Red Blood Velocities in Patients With BRVO and Healthy Subjects
Assessment of retinal vessel calibers combined with bidirectional Fourier domain optical coherence tomography (FDOCT) for measurement of retinal blood velocities is a new and sophisticated method for assessing retinal blood flow…
- Conditions
- Branch Retinal Vein Occlusion, Retinal Blood Flow, Retinal Oxygen Saturation
- Trial name
- NCT01746615
- Testing
- Dynamic Vessel Analyzer, Bidirectional Fourier-Domain Optical Coherence Tomography (FDOCT)
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Trauma From Occlusion
Comparative Evaluation of Periodontal Status and Periodontal Parameters in Different Age Group Individuals With and Without Trauma From Occlusion.
Trauma from occlusion (TFO) is defined as an injury resulting in tissue changes within the attachment apparatus as a result of occlusal forces (Glossary of Periodontic Terms American Academy of Periodontology, 2001) This clinical…
- Trial name
- NCT06999889
- Testing
- Recording of Periodontal Parameters.
- Where
- India
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Chest Pain, Coronary Occlusion
Advanced Cardiovascular Imaging Consortium
The ACIC is a Collaborative Quality Improvement (CQI) program involving the collection of data related to: indications for Coronary Computed Tomography (CCTA), patient health characteristics, acquisition techniques of CCTA scans…
- Conditions
- Chest Pain, Coronary Occlusion, Coronary Artery Disease
- Trial name
- ACIC (NCT00640068)
- Where
- 50 sites in United States
- Volunteers
- 42,926 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Temporomandibular Joint Dysfunction Syndrome, Tooth Injuries
Effectiveness of Three Oral Devices as Mouthguard in Electroconvulsive Therapy. Randomized Crossover Clinical Trial.
This observer-blind crossover intervention study aims to determine the most effective type of device as oral mouthguard in modified-Electroconvulsive Therapy (m-ECT) comparing three types of devices: standard, prefabricated and…
- Conditions
- Temporomandibular Joint Dysfunction Syndrome, Tooth Injuries, Dental Occlusion, Traumatic
- Trial name
- NCT02678715
- Testing
- Solubrux®, Customized Appliance, Somatics®
- Where
- Spain
- Volunteers
- 4 people
- Sponsor
- Eva Willaert Jiménez-Pajarero
Ischemic Stroke, Atrial Fibrillation
Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy
Atrial fibrillation (AF) is one of the most common cardiac arrhythmias and cardioembolic stroke due to AF is its major complication. Direct oral anticoagulants (DOAC) reduce the risk of cardioembolism in patients with AF.
- Trial name
- ELAPSE (NCT05976685)
- Testing
- Left atrial appendage Occlusion, DOAC
- Where
- 33 sites in Belgium, Germany and 4 more
- Volunteers
- 482 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hidradenitis Suppurativa, Hidradenitis
Hydroxychloroquine for the Treatment of Hidradenitis Suppurativa
Hidradenitis suppurativa (HS) is an under-recognized and debilitating disease. Patients suffer from recurring painful abscesses and scarring in their armpits, under the breasts, groin and other areas of the body.
- Conditions
- Hidradenitis Suppurativa, Hidradenitis, Acne Inversa, Boils
- Trial name
- NCT03275870
- Testing
- Hydroxychloroquine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Elena Gonzalez Brant, MD
Macular Edema
Major and Macular Branched Retinal Venous Occlusion
Although it is important in the clinical management to classify BRVO into subtypes based on the location of the occlusion (major or macular), few studies have provided such information[8,9].
- Trial name
- NCT01219205
- Testing
- intravitreal bevacizumab
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Hallym University Medical Center
Malocclusion, Open Bite
Anterior Open Bite Treatment With Bonded Spurs Associated With Build-ups Versus Conventional Bonded Spurs
This study compares the dentoalveolar and skeletal effects of bonded spurs associated with build-ups versus conventional bonded spurs in the early treatment of anterior open bite patients.
- Trial name
- NCT03702881
- Testing
- Bonded Spurs associated with posterior build-ups, Conventional bonded spurs
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Congenital Diaphragmatic Hernia
Fetal Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia
The purpose of the study is to study the efficacy of fetal endoscopic tracheal occlusion (FETO) in cases of severe congenital diaphragmatic hernia (CDH).
- Trial name
- FETO (NCT05461222)
- Testing
- Balt "Goldballoon"
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yair Blumenfeld
Edentulous Jaw
Occlusion and Disocclusion Time in Immediately Loaded Overdentures Supported by Two Splinted Versus Non Splinted Interforaminal Implants
complete denture wearers struggle to eat well with their dentures due to poor denture retention, stability, and occlusal disharmony.
- Trial name
- NCT06376019
- Testing
- solitary Implant loading with ball attachment, splinted Implant loading with intra oral welding, complete denture
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Acute Stroke
SEACOAST 1- SEdAtion With COllAteral Support in Endovascular Therapy for Acute Ischemic Stroke
SEACOAST 1 is a prospective, randomized, blinded endpoint trial comparing collateral vigor and clinical outcomes, with different forms of GA in patients with acute ischemic stroke due to anterior circulation large vessel…
- Trial name
- SEACOAST (NCT03737786)
- Testing
- Tight control of end-tidal CO2 levels
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.