Clinical trials: Dental Occlusion
Uterine Leiomyoma, Uterine Fibroid
ABSOLUTELY: A Temporary Uterine Blood Supply Occlusion for Laparoscopic Myomectomy in Patients With UTErine LeiomYoma
A phase 3 multicenter unblinded randomized controlled trial comparing the temporary uterine blood supply occlusion with conventional approach during laparoscopic myomectomy in patients with uterine leiomyoma.
- Conditions
- Uterine Leiomyoma, Uterine Fibroid, Leiomyoma, Uterine, Myoma;Uterus
- Trial name
- NCT04519593
- Testing
- Laparoscopic myomectomy with prior temporary uterine blood supply occlusion, Conventional laparoscopic myomectomy
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Mother and Child Clinic Saint-Petersburg
Stroke, Acute, Cerebrovascular Disorders
Therapy Evaluation in Patients With Minor Stroke and Large Vessel Occlusion
This multicenter registry study, which record the therapy strategy and follows up these acute ischemic stroke (AIS) patients with low NIHSS and large vessel occlusion (LVO), is intended to provide the important data for therapy…
- Conditions
- Stroke, Acute, Cerebrovascular Disorders, Brain Diseases, Central Nervous System Diseases
- Trial name
- TEMPOS (NCT06633809)
- Testing
- Immediate endovascular therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sir Run Run Shaw Hospital
Basilar Artery Occlusion, Posterior Circulation Brain Infarction
Cerebrolysin as an Add-On Therapy to Standard Treatment of Basilar Artery Occlusion
The standard therapy for acute ischemic posterior circulation stroke (PCS) often leads to poor functional outcomes and high mortality rates, despite all advances in reperfusion therapy.
- Trial name
- NCT06489925
- Testing
- Cerebrolysin
- Volunteers
- 20 people
- Sponsor
- University Hospital Sestre Milosrdnice
Ischemic Stroke, Large Vessel Occlusion
Advancing Reperfusion Therapy for Ischemic Stroke: Direct Transfer to Angiography Suite for Patients With Suspected Large Vessel Occlusion
The investigators initiated a multicenter, prospective, randomized, open-label, blinded-endpoint (PROBE) controlled trial to evaluate the efficacy and safety of the direct transfer to angiography suite (DTAS) triage strategy…
- Trial name
- ARTS-DTAS (NCT07460713)
- Testing
- direct transfer to angiography suite, conventional CT/MRI triage strategy
- Where
- China
- Volunteers
- 568 people
- Sponsor
- Beijing Tiantan Hospital
Uterine Fibroids (Leiomyoma), Myomectomy
Bilateral Uterine Artery Occlusion During Laparoscopic Myomectomy
The current study is a multiple-arm, single blinded, and controlled randomized trial. It will be conducted in two gynecological endoscopy centers: • ElShatby University Hospital, a tertiary level hospital in Alexandria, Egypt.
- Conditions
- Uterine Fibroids (Leiomyoma), Myomectomy, Myomectomy; Surgical Blood Loss
- Trial name
- NCT07352761
- Testing
- Temporary clipping of uterine artery, Temporary occlusive suturing of uterine artery, Bipolar coagulation of uterine arteries
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Arterial Line, Ischemia
Subcutaneous Nitroglycerin to Prevent Radial Artery Occlusion in Children
The primary objective of the study is to evaluate the vasodilative effect of subcutaneous nitroglycerin to prevent radial arterial occlusion(RAO) after removal of the radial arterial catheter in pediatric patients.
- Trial name
- NCT05443061
- Testing
- Nitroglycerin, Normal saline
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Chronic Total Occlusion of Coronary Artery, Microvascular Coronary Artery Disease
Microvascular Coronary Resistance and Absolute Coronary FLOW in Patients With Percutaneous Intervention of a Chronic Total Occlusion
It is an observational study which objective is to analyze, through a series of invasive parameters, the state of the coronary microvasculature immediately after the successful percutaneous coronary intervention of a chronic…
- Conditions
- Chronic Total Occlusion of Coronary Artery, Microvascular Coronary Artery Disease, Coronary; Ischemic, Coronary Microvascular Dysfunction
- Trial name
- FLOW-CTO (NCT05197361)
- Testing
- Invasive coronary physiology
- Where
- 4 sites in Spain
- Volunteers
- 34 people
- Sponsor
- Parc de Salut Mar
Ileostomy - Stoma
Novel Stomal Occlusion Device in Patients With a Brooke Ileostomy
This investigation constitutes an initial evaluation of the stoma occlusion device in humans with a mature permanent Brooke ileostomy.
- Trial name
- NCT03549780
- Testing
- Stomal Occlusion Device
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- William A. Faubion, M.D.
Femoropopliteal Artery Occlusion
Outcome of Endovascular Therapies in Chronic Femoropopliteal Occlusive Disease With Severe Calcification
This study is a prospective, multicenter, real world, observational study, which aims at evaluating the safety, efficacy and economic cost of endovascular treatments for endovascular therapies in chronic femoropopliteal occlusive…
- Trial name
- NCT04716361
- Where
- China
- Volunteers
- 600 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Anaesthesia, Anxiety
Impact of AR Glasses on Children's Behavior During Dental Nerve Blocks
The aim of this study is to evaluate the effectiveness of augmented reality glasses in managing pain, anxiety, and behavior in pediatric patients during inferior alveolar nerve block Group A (Control group): inferior alveolar…
- Trial name
- NCT06724341
- Testing
- Distraction
- Where
- Syria
- Volunteers
- 108 people
- Sponsor
- Damascus University
Atrial Fibrillation, Heart Diseases
Left Atrial Appendage Occlusion With WATCHMAN® Device in Patients With Non-valvular Atrial Fibrillation and End-stage Chronic Kidney Disease on Hemodialysis
Atrial fibrillation (AF) is more common in patients with renal disease compared to the general population an risk increase to as much as 10 times in patients on hemodialysis (HD).
- Conditions
- Atrial Fibrillation, Heart Diseases, Renal Disease, Bleeding
- Trial name
- WATCH-HD (NCT03446794)
- Testing
- Non Intervention
- Where
- 20 sites in Spain
- Volunteers
- 300 people
- Sponsor
- Fundación EPIC
Non-acute Carotid Artery Occlusion, Cognitive Impairment
Endovascular Treatment for Symptomatic Non-acute Carotid Occlusion
This study is a multicenter, prospective, randomized, open-label, blinded-endpoint clinical trial designed to evaluate the safety and potential efficacy of endovascular recanalization strategies in patients with symptomatic…
- Trial name
- ASCENT (NCT07803419)
- Testing
- Guideline-Based Best Medical Treatment, Endovascular Recanalization With Proximal Balloon Protection, Endovascular Recanalization Without Proximal Protection
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Dapeng Mo
STEMI - ST Elevation Myocardial Infarction
Semi Occlusion of the Coronary Sinus as an Adjunct to PCI in STEMI Patients, FIH Clinical Study
The present study is planned to evaluate the safety and feasibility of the Booster Balloon catheter when applied to STEMI patients.
- Trial name
- NCT05557019
- Testing
- Booster Balloon Catheter
- Where
- 2 sites in Georgia, Israel
- Volunteers
- 20 people
- Sponsor
- Intratech Medical Ltd.
Central Retinal Vein Occlusion
Ranibizumab Intravitreal Injections Versus Sham Control in Patients With Central Retinal Vein Occlusion (CRVO)
Provide efficacy and safety data on intravitreal injections of ranibizumab 0.5 mg in patients with visual impairment due to macular edema secondary to CRVO
- Trial name
- Camellia (NCT01976312)
- Testing
- Ranibizumab 0.5 mg
- Where
- 34 sites in China, Hong Kong and 5 more
- Volunteers
- 252 people
- Sponsor
- Novartis Pharmaceuticals
Subarachnoid Hemorrhage, Subarachnoid Hemorrhage, Aneurysmal
Intrasaccular neCk Occlusion deVice Treatment of Intracranial Aneurysm in Acute Subarachnoid hemorRhAGE
Rationale: Intrasaccular neck occlusion devices have been used for unruptured aneurysm without safety concerns and good occlusion rates.
- Trial name
- COVERAGE (NCT05171465)
- Testing
- Neqstent or Contour
- Volunteers
- 120 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Coronary Heart Disease
Recovery of Left Ventricular Function in Chronic Total Occluded Coronary Arteries
The study is a randomised comparison of recanalisation of chronic occluded coronary arteries with implantation of Sirolimus eluting stents and medical therapy.
- Trial name
- REVASC (NCT01924962)
- Testing
- revascularisation
- Where
- Germany
- Volunteers
- 205 people
- Sponsor
- University Heart Center Freiburg - Bad Krozingen
Chronic Middle Cerebral Artery Occlusion, Stenting Treatment
Prospective Study on Safety and Efficacy of Stenting for Chronic Middle Cerebral Artery Occlusion With Limb Dysfunction
The goal of this clinical study is to evaluate the safety and efficacy of stenting for revascularization treatment of chronic middle cerebral artery (MCA) occlusion in patients with chronic MCA occlusion.
- Conditions
- Chronic Middle Cerebral Artery Occlusion, Stenting Treatment, Modified Rankin Scale, National Institutes of Health Stroke Scale
- Trial name
- NCT06419283
- Testing
- Middle Cerebral Artery Stent Implantation, standard treatment with aspirin.
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Huizhou Municipal Central Hospital
Dental Caries
DPBRN Longitudinal Study of Questionable Occlusal Caries Lesions
The purpose of this study will allow us to observe and follow the subjects' treatment from DPBRN Prevalence of Questionable Occlusal Caries Lesions Study over a 24 month period.
- Trial name
- NCT01309971
- Where
- 7 sites in United States, Denmark
- Volunteers
- 2,624 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Acute Ischemic Stroke, Vessel Occlusion
Tirofiban After Successful MT Recanalization in AIS
Acute ischemic stroke with large vessel occlusion is a frequently occurring life-threatening condition. Although endovascular treatment can effectively open occluded vessels, the successful reperfusion rate exceeds 80%, but the…
- Trial name
- ATTRACTION (NCT06265051)
- Testing
- Tirofiban
- Where
- China
- Volunteers
- 1,380 people
- Sponsor
- Xiang Luo
Wet Macular Degeneration, Age-related Macular Degeneration
Dorzolamide-timolol Drops With Injections to Treat AMD, RVO or DME.
This study seeks to evaluate the effect of topical aqueous suppression on the anatomic and functional response to intravitreal anti-vascular endothelial growth factor (VEGF) injections in non-responders with wet age-related…
- Conditions
- Wet Macular Degeneration, Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion
- Trial name
- NCT02571972
- Testing
- Dorzolamide-timolol
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Wills Eye
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