Clinical trials: Dental Restorations
Dental Caries in Children
Aesthetic Restorations in Deciduous Anterior Teeth
This study proposes to conduct a randomized clinical trial (RCT), composed of a sample of 194 deciduous central and lateral incisors with active cavitated lesions, simplified ICDAS C+ score, with involvement of more than two…
- Trial name
- NCT05875064
- Testing
- Restoration with resin composite and polyvinyl crown, Restoration with conventional resin composite
- Volunteers
- 194 people
- Sponsor
- University of Nove de Julho
Endodontically Treated Teeth, Nonvital Teeth
Clinical Comparison of Lithium Disilicate and 3D-Printed Resin Endocrowns
This randomized controlled clinical trial aims to compare the clinical performance of CAD/CAM lithium disilicate (IPS e.max CAD) and 3D-printed resin (BEGO VarseoSmile TriniQ) endocrown restorations in endodontically treated…
- Conditions
- Endodontically Treated Teeth, Nonvital Teeth, Restoration of Endodontically Treated Posterior Teeth
- Trial name
- NCT07874906
- Testing
- IPS e.max CAD Lithium Disilicate Endocrown, BEGO VarseoSmile TriniQ Resin Endocrown
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medipol University
Dental Caries
DPBRN Longitudinal Study of Dental Restorations Placed on Previously Un-restored Surfaces
The purpose of this study is to assess the quality and expected lifespan of fillings recorded in the DPBRN "Reasons for placing the first restoration on permanent tooth surfaces" study, and the factors affecting how long the…
- Trial name
- NCT01201408
- Where
- 7 sites in United States, Denmark
- Volunteers
- 9,291 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Dental Caries
Clinical Comparison of Bulk-fill Restorative and Nano-fill Resin Composite
The aim of this study is to evaluate the clinical performance of a nano-fill and a bulk fill resin composite in class II restorations.
- Trial name
- NCT04320576
- Testing
- Bulk-fill, Nano-fill
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Implants, Edentulous
Tissue Level vs Bone Level Implants for Plural Restorations : a Multicentre Randomised Controlled Trial
Anthogyr Axiom Tissue-Level implants and corresponding Multi-Unit abutments recently enriched the available product range for dental surgeons.
- Trial name
- IBERICA (NCT05223387)
- Testing
- Axiom TL REG, Axiom BL REG
- Where
- 3 sites in Portugal, Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Anthogyr
Dental Restoration, Temporary
Effect of Temporization on the Peri-implant Soft Tissue of Immediate Implants: Randomized Controlled Clinical Trial
This parallel arms, randomized controlled clinical trial will involve 22 systemically free patients with an unrestorable tooth in the upper esthetic zone. They will be randomly allocated to two equal groups.
- Trial name
- NCT03970811
- Testing
- Immediate Implants, temporary restoration, final restoration
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Misr International University
Tooth Loss, Dental Implant, Single-tooth
RCT of BLT Implants Used for Immediate vs Early Placement, Restored With Ceramic Crowns on Titanium Bonding Bases.
The purpose of this study is to assess the outcome of a new bone level tapered implant when inserted either following an immediate placement protocol or an early placement approach and restored with single crowns out of two…
- Trial name
- BLT (NCT05079542)
- Testing
- Timepoint of Implant placement of Bonelevel tapered implants, Material for tooth restoration - Lithiumdisilicate glass ceramic or zirconia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Benign or Malignant Tumour of the Oral Cavity, Stage III-IV Osteonecrosis
Validation of the O-bridge Protocol: a Prospective, Multicenter Trial
Surgical reconstruction to restore oral function and aesthetics after major ablative surgery in the oral cavity forms a challenge to maxillofacial surgeons, and greatly impacts patient' quality of life (QOL).
- Conditions
- Benign or Malignant Tumour of the Oral Cavity, Stage III-IV Osteonecrosis, Mandibular Reconstruction, Fixed Dental Restoration
- Trial name
- NCT04007783
- Where
- 5 sites in Belgium
- Volunteers
- 80 people
- Sponsor
- AZ Sint-Jan AV
Periodontal Health, Endodontically Treated Teeth
Deep Margin Elevation in Endodontically Treated Posterior Teeth
This study aims to evaluate the periodontal response of proximal surfaces with deep margin elevation (DME) in endodontically treated posterior teeth restored with CAD/CAM systems.
- Trial name
- DME-PERIO (NCT07661719)
- Testing
- Deep Margin Elevation, CAD/CAM Restoration Without DME
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Zirconia Monolithic Dental Restorations: In-mouth Behaviour, LTD and Wear
Y-TZP and In-mouth Low Thermal Degradation: A Prospective Clinical Study
The objective of this work is to study in-mouth aging and LTD of monolithic zirconia restorations. Microstructural changes characteristic of LTD processes, wear, and clinical behaviour following standard parameters will be…
- Trial name
- NCT02150226
- Testing
- Lava plus (3M) crowns and bridges
- Where
- Belgium
- Volunteers
- 101 people
- Sponsor
- University of Liege
Post-operative Pain, Dental Caries
The Effect of Different Lining Strategies on Amalgam Restorations
The aim of this research is to compare the clinical outcome of amalgam restorations placed in conjunction with three different lining protocols, each of which represents a different therapeutic concept.
- Trial name
- NCT02435459
- Testing
- No lining, Calcium Hydroxide cement, RMGI cement
- Where
- United Kingdom
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Bite Force, Stainless-steel Crown
Bite Force Recovery Following Pediatric Full Crown Restorations
A component of masticatory function is bite force. Dental caries is one factor that contributes to poor dental health, which has an overall negative influence on quality of life.
- Conditions
- Bite Force, Stainless-steel Crown, Masseter Muscle
- Trial name
- NCT07786805
- Testing
- Preformed BioFlx Crown, Preformed Stainless Steel Crown
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Dental Caries
Cost-efficacy of Sealing Moderate Caries Lesions in Occlusal Surfaces of Primary Molars
This protocol aims to assess the cost-efficacy and applicability of the treatment of lesions moderate caries using sealants as an alternative to the restorations on occlusal surfaces of deciduous teeth.
- Trial name
- NCT03005405
- Testing
- Ionomer Restoration (control), Ionomer Sealant (test), Oral hygiene orientation and professional fluoride application
- Where
- Brazil
- Volunteers
- 96 people
- Sponsor
- University of Sao Paulo
History of at Least One Coronal Dental Restoration
Evaluation of Dental Coronal Restorations
The purpose of this study is to provide the latest information on the oral health status of patients, the lifetime of restorations, to quantify the incidence of defects rates on inserted restorations in conservative dentistry.
- Trial name
- RESTO DATA (NCT03854526)
- Testing
- Evaluation of the quality of direct and indirect partial dental coronal restorations in adults
- Where
- 61 sites in France
- Volunteers
- 863 people
- Sponsor
- Hospices Civils de Lyon
Dental Restoration, Permanent
10 Years Evaluation of Composite Restoration
This randomised, split-mouth clinical study evaluated the marginal quality of direct Class I and Class II restorations made of microhybrid composite and applied using two polymerisation protocols,
- Trial name
- NCT02764450
- Testing
- Astralis 10 HPM, Astralis 10 RM
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- BNM Clinic and Research
Carious Lesion, Restoration
Clinical Performance of Novel Coconut Based Restorative Material.
A triple-blind, parallel group, randomized trial with an allocation ratio of 1:1. Participants randomly allocated into two groups A and B.
- Trial name
- NCT07640074
- Testing
- Nano-reinforced glass ionomer, glass ionomer without nanoparicles
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dental Caries
Investigation of the Effect of Deep Margin Elevation Technique on the Clinical Performance of Endocrown Restorations Produced by Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) System
The aim of this clinical study is to investigate the impact of the deep margin elevation technique on the clinical performance of CAD/CAM endocrown restorations in deep Class II cavities.
- Trial name
- NCT06222918
- Testing
- Deep Margin Elevation (G-ænial Universal Injectable)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Caries
Clinical Performance Evaluation of a Glass-ionomer Restorative System Evaluation
The aim of this clinical trial was to compare the clinical performances of a glass ionomer restorative system with a micro hybrid resin based composite in class I and class II cavities.
- Trial name
- NCT03822403
- Testing
- EQUIA, Gradia Direct Posterior
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Restoration Failure of Marginal Integrity
Different Application Strategies When Using Ambar Universal in Class V Cavities
Treatment clinical trial, randomized, controled, parallel, double-blinded, with four groups, that aims to evaluate the best application strategy when using a new Universal Adhesive system, Ambar Universal (FGM, Joinville…
- Trial name
- AUC (NCT02948686)
- Testing
- Self-Etching Application Strategy, Enamel Etching Application Strategy, Self Etching with Extended time Application Strategy
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dental Caries, Class II Dental Caries
5-year Clinical Follow-up of Restorative Materials
Materials to be used as permanent filling materials in Class II restorations are still an essential field of study. This study aims to evaluate the 5-year clinical performance of Class II restorations performed with different…
- Trial name
- NCT06393270
- Testing
- Modified US Public Health Service (USPHS) criteria
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people
- Sponsor
- Selcuk University