Clinical trials: Dental Surgery
Dental Implants, Maxillary Diseases
"Computer-Guided vs Freehand Zygomatic Implant Placement
This randomized trial compares computer-guided versus free-hand zygomatic implant placement in patients with atrophic maxillae or maxillary defects.
- Trial name
- NCT06925438
- Testing
- Computer-guided zygomatic implant system, free-hand zygomatic implant placement
- Where
- 2 sites in Egypt
- Volunteers
- 8 people
- Sponsor
- Al-Azhar University
Jaw, Edentulous, Partially
Clinical Study Comparing Submerged Versus Trans-mucosal Healing of P.004 Implants in the Anterior Mandible and Maxilla
The purpose of this study is To demonstrate that there is no difference in change in bone level around P.004 implants between 1st stage surgery and 6 months post surgery when transmucosal implant placement is compared to…
- Trial name
- NCT00906425
- Testing
- Straumann Bone Level Implant
- Where
- 11 sites in United States, Australia and 5 more
- Volunteers
- 145 people
- Sponsor
- Institut Straumann AG
Local Analgesia Via Infiltration, Wound Heal
Comparison of Postoperative Effects of Articaine and Lidocaine in Mucogingival Surgery
The aim of this study is to compare and evaluate the effects of using lidocaine 2% (with adrenaline) and articaine 4% (with adrenaline) in free gingival graft (FGG) surgery on postoperative wound healing, changes in blood flow in…
- Conditions
- Local Analgesia Via Infiltration, Wound Heal, Pain, Postoperative, Hemorrhage
- Trial name
- NCT07145879
- Testing
- Lidocaine hydrochloride 2% with epinephrine 1:100 000, Articaine 4% with epinephrine 1:100,000, Free gingival graft (FGG)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Dental Trauma
Evaluation of Functional Versus IADT Splinting Times on Tooth Mobility After Surgical Extrusion
The objective of this study is to compare functional splinting time effect versus the suggested splinting time of (IADT) effect on tooth mobility and possible healing outcomes for surgically extruded permanent anterior teeth with…
- Trial name
- NCT03700866
- Testing
- Functional splinting time
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Partial Edentulism, Dental Implant
Immediate vs Conventional Loading With Different Crown Materials on Immediately Placed Single Implants
This randomized controlled trial compares immediate and conventional loading of single implants placed immediately into fresh extraction sockets in the upper front and premolar region.
- Conditions
- Partial Edentulism, Dental Implant, Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement
- Trial name
- NCT07882095
- Testing
- Conventional loading, Monolithic zirconia crown, Permanent 3D-printed PMMA crown
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Intubating Conditions
Propofol-sevoflurane Induction for Pediatric Nasotracheal Intubation.
Pediatric anesthesia differs significantly from adult anesthesia due to physiological differences and increased sensitivity to anesthetic agents.
- Trial name
- NCT07680400
- Testing
- reduced pharmacologic exposure, conventional anesthetic induction
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Bezmialem Vakif University
Dental Implants
Implants Immediately Installed in Esthetic Area With Computer-guided Surgery
The objective of this randomized and longitudinal clinical study is to compare the installation of immediate implants in the esthetic zone through computer-guided-surgery and conventional surgery.
- Trial name
- NCT03986164
- Testing
- Guided surgery with bovine spongious bone substitute, Conventional surgery with bovine spongious bone substitute
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dental Implant
Apically Positioned Flap vs Rolled Flap for Soft Tissue Management During Implant Second-Stage Surgery
Patients are being asked to consider joining a research study that looks at two different ways dentists uncover dental implants during a small gum surgery.
- Trial name
- NCT07595211
- Testing
- Apically Positioned Flap (APF), Rolled Flap Technique (RFT)
- Volunteers
- 16 people
- Sponsor
- Ohio State University
Postoperative Pain
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-182)
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
- Trial name
- NCT00092313
- Testing
- MK0966, rofecoxib, Comparator: oxycodone and acetaminophen
- Volunteers
- 271 people
- Sponsor
- Merck Sharp & Dohme LLC
Postoperative Pain
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-183)
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
- Trial name
- NCT00092326
- Testing
- MK0966, rofecoxib
- Volunteers
- 269 people
- Sponsor
- Merck Sharp & Dohme LLC
Edentulism
The Success of Implant-borne Prostheses Following Fully-guided Static Computer-assisted Implant Surgery.
This study aims to determine the success of implant-borne prostheses and the accuracy of implant placement that can be achieved using fully guided static Computer Assisted Implant Surgery (sCAIS).
- Trial name
- NCT06794138
- Testing
- dental implant placement
- Where
- Hungary
- Volunteers
- 13 people
- Sponsor
- Semmelweis University
Partially Edentulous Jaw, Tooth Loss
Clinical Safety and Effectiveness of the Straumann Dynamic Navigation System Falcon
The Falcon Study is a prospective, multicenter, multinational clinical investigation evaluating the Straumann® Dynamic Navigation System (Falcon) for dental implant placement.
- Conditions
- Partially Edentulous Jaw, Tooth Loss, Dental Implant
- Trial name
- Falcon (NCT07518615)
- Testing
- Post-operative Cone Beam Computed Tomography (CBCT), Straumann Falcon Dynamic Navigation System, Dental Implants
- Where
- 4 sites in Belgium, Italy and 2 more
- Volunteers
- 75 people
- Sponsor
- Institut Straumann AG
Impacted Mandibular Third Molar Extraction, Dental Anxiety
Effects of Preoperative Information Formats in Third Molar Surgery
This study evaluates whether physician-guided visual information provided before impacted mandibular third molar surgery can improve hemodynamic stability during the perioperative period.
- Trial name
- NCT07484334
- Testing
- Standard Verbal Information, Real Surgical Video Information, 3D Animation Video Information
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Recep Tayyip Erdogan University
Mandibular Hypoplasia
Applicability Clinic of Cement Portland Structural White in Endodontic Surgery
Thirty teeth twelve patients, two female and a male, who had persistent periradicular lesions were selected to participate in this study.
- Trial name
- NCT02474615
- Testing
- ENDODONTIC SURGERY
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Dental Implants, Peri-Implantitis
Increased Peri-implant Keratinized Mucosal Thickness at Different Operative Times
Keratinized mucosa, which is composed of free gingiva and attached gingiva, is a barrier against bacterial invasion in oral cavity and provides good tissue sealing for periodontal environment.
- Trial name
- NCT04683991
- Testing
- Subepithelial connective tissue graft
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pain, Postoperative
Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain
Once patients' postoperative pain intensity reaches a moderate-to-severe level, they are randomized to receive intranasal ketamine or placebo.
- Trial name
- NCT00488787
- Testing
- intranasal ketamine
- Volunteers
- 40 people
- Sponsor
- Javelin Pharmaceuticals
Acute Pain
Analgesic Efficacy and Safety of ADL5859 in Subjects With Acute Dental Pain After Third Molar Extraction
The objective of this study is to evaluate the analgesic efficacy and safety of ADL5859 compared with placebo and an active control (ibuprofen) in subjects with acute dental pain after third molar extraction.
- Trial name
- NCT00993863
- Testing
- ADL5859 30 mg, ADL5859 100 mg, ADL5859 200 mg
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Bone Resorption, Dental Diseases
Allogeneic Bone Paste Versus Allogeneic Bone Powder
Autogenous bone graft has been considered the gold standard in Guided Bone Regeneration (GBR) technique used for bone augmentation.
- Trial name
- NCT04141215
- Testing
- BIOBank bone paste, BIOBank cortico-cancellous bone powder
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Biobank
Periodontal Disease, Non-diseased Patients
The Importance of Periostin in Periodontal Health and Disease
The goal of this study is to determine the clinical importance of Periostin in oral health and disease. The long-term goal will be to develop practical applications for the diagnosis, treatment, prevention and cure of human…
- Trial name
- NCT01180920
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Bone Augmentation
Evaluation of the Safety and Performance of the Neobone®: A Prospective Observational Study in Dental Area
This study aims to collect real-world clinical data to gather information on the performance and safety of the Neobone® when used according to its intended purpose and current clinical applications.
- Trial name
- NeoDent01 (NCT07179497)
- Where
- Portugal
- Volunteers
- 66 people
- Sponsor
- Bioceramed