Clinical trials: Dental Trauma, open to volunteers
Dental Implant, Wound Healing
Lactoferrin Nanohydrogel for Soft And Hard Tissue Healing and Implant Stability in Immediate Implant Placement
The goal of this randomized clinical trial is to evaluate whether local application of a 4% bovine lactoferrin nanohydrogel improves soft tissue healing, bone healing, and implant stability following immediate dental implant…
- Trial name
- LF (NCT07889674)
- Testing
- 4% bovine lactoferrin nanohydrogel
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Future University in Egypt
Oral Health, Dental Trauma
Sport Mouthguards: Devices for Preventing Dental Injuries in Sports
Objective: To evaluate the impact of mouthguards (MG) on acceptability, incidence of soft tissue injuries, periodontal and salivary parameters, as well as on the perception of the body in sports practice (PeCoPes) and on the…
- Conditions
- Oral Health, Dental Trauma, Oral Health Knowledge, Attitude and Practice Among Patients, Mouth Protectors
- Trial name
- NCT06912451
- Testing
- Sport custom mouthguard
- Where
- Brazil
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Dental Implant, Healing Wound
Influence of Timing of Implant Placement on Early Healing Molecular Events
Dental implants have been on the market for several years and they are routinely used to replace single/multiple missing teeth with a high success rate.
- Conditions
- Dental Implant, Healing Wound, Biomarkers, Saliva
- Trial name
- NCT06276335
- Testing
- Immediate implant placement and guided bone regeneration (Test), Late implant placement and guided bone regeneration (Control)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Queen Mary University of London
Mouthguard Use Orofacial Injuries Prevention 3D Printed Mouthguard Traditional Custom-made Mouthguard Occlusal Thickness Changes
Comparative Assessment of Thickness Changes in 3D-Printed vs. Custom-Made Mouth Guards for Children in Contact Sports
This study aims to compare changes in the thickness of traditional and 3D-printed custom mouth guards in pediatric athletes who participate in contact sports.
- Trial name
- NCT07000435
- Testing
- 3D printed custom-made mouth guards, Traditional custom-made mouth guards
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Injuries, Dental Restoration, Permanent
Colour Match, Stability, and Patient's Satisfaction of Single-Shade Composites in Anterior Teeth
The goal of this observational study is to evaluate the clinical performance of a single-shade composite resin, used with an injection moulding technique, in restoring maxillary incisors affected by traumatic dental injury in…
- Trial name
- NCT07309653
- Where
- Thailand
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Jaw Tracking, Occlusion
Evaluation of the Impact of Integrating Dynamic Patient-Specific Motion and Implementing a Jaw Tracking System in the Attribution of the Occlusion in Full-Arch Restorations Through a Digital Workflow: A Clinical Study
The maxillomandibular relationship of diagnostic and definitive casts is a fundamental procedure in prosthodontics. Depending on the prosthodontic treatment involvement, different maxillomandibular relationship records can be…
- Trial name
- NCT06773728
- Testing
- Record occlusal contacts, Tracking of jaw movement
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Dental Caries, Dental Occlusion
Occlusal Impact of Hall Crowns in Primary Molars
Hall Technique is a non-invasive restorative approach for managing carious primary molars, increasingly used in pediatric dentistry due to its simplicity and patient tolerance.
- Conditions
- Dental Caries, Dental Occlusion, Pediatric Dentistry
- Trial name
- NCT07134114
- Testing
- Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Caries,Dental, Broken Teeth
Evaluation of CAD/CAM Onlays Fabricated by Subtractive Versus Additive Digital Manufacturing Techniques.
Aim of the study: The aim of this RCT is to evaluate CAD/CAM onlays fabricated by subtractive technique (brilliant crios) versus additive technique (varseosmile crown plus material), in terms of clinical functional evaluation…
- Conditions
- Caries,Dental, Broken Teeth, Fracture Tooth, Defective Dentition
- Trial name
- NCT05943782
- Testing
- onlay manufactured by milling, Onlay manufactured by 3D printing
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy Adult Participants, Tooth Fracture
The Impact of Adhesion Strategy on the Clinical Performance Of Indirect Dental Restorations
The goal of this clinical trial is to evaluate whether different cement systems influence the clinical outcome of posterior tooth supported zirconia crowns in adult patients requiring single crown restorations.
- Trial name
- NCT07644676
- Testing
- Resin cement, Glass-ionomer cement
- Where
- 2 sites in Sweden
- Volunteers
- 110 people
- Sponsor
- Malmö University
Dental Occlusion, Primary Teeth
Digital Occlusal Analysis and Bite Force Evaluation of Primary Molars Restored With Zirconia Crowns Using T-Scan
The goal of this observational study is to evaluate the adaptation of occlusion and bite force after zirconia crown restoration in children with pulp-treated primary molars.
- Conditions
- Dental Occlusion, Primary Teeth, Pulp-treated Primary Molars, Zirconia Crowns
- Trial name
- NCT07276841
- Testing
- Pulp Therapy and Zirconia Crown Restoration of Primary Molars with T-Scan Occlusal Analysis
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Cairo University
Endosseous Dental Implant Failure, Accident Caused by Broken Ceramic
Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation Behavior
In patients rehabilitated with a full-arch (maxillary and/or mandibular) implant-supported fixed prosthesis, do three CAD/CAM zirconia framework designs - porcelain-veneered zirconia (PVZ), monolithic zirconia with buccal veneer…
- Trial name
- NCT01974362
- Testing
- Dental Implant, Monolithic Zirconia (MZ), Zirconia-Feldspathic (PVZ)
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Postoperative Infections, Mandibular Nerve Injuries
Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI Model
The goal of this observational study is to learn how to better predict and prevent intra- and postoperative complications in oral surgery in adult patients referred for oral surgical procedures.
- Conditions
- Postoperative Infections, Mandibular Nerve Injuries, Alveolar Osteitis, Complication
- Trial name
- NCT07461324
- Where
- 2 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Periapical Diseases
Detection of Periapical Lesions on Dental Panoramic Radiographs Based on Artificial Intelligence
Dental periapical damages can have various reasons and is reflected by a radiolucent lesion on complementary imaging: angulated retro-alveolar (RA) radiographs, dental panoramic radiographs, and three-dimensional imaging such as…
- Trial name
- OPTITOMO (NCT05888935)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Dental Occlusion, Occlusal Wear of Teeth
Evaluation of Occlusal Adjustment Material Removal on Monolithic Zirconia Blocks: An In Vitro Study
This study aims to improve understanding of the amount of tooth-replacement material removed during a single grinding "stroke" performed in the adjustment of a zirconia crown.
- Conditions
- Dental Occlusion, Occlusal Wear of Teeth, Fixed Dental Prosthesis
- Trial name
- NCT07280130
- Testing
- perform material removal on monolithic zirconia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Bone Graft
Acellular Collagen Matrix as a Tool to Obtain Wound Closure Following a Guided Bone Regeneration Procedure
Guided bone regeneration (GBR) is a procedure used to increase the amount of bone volume in the jaw before placing a dental implant.
- Trial name
- NCT06871735
- Testing
- Acellular matrix, Surgical closure
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Tooth Loss and Rehabillitation, Dental Implant Failure
Safety Assessment of Placing a Single Dental Implant Without Antibiotic Prophylaxis in Simple Cases: A Pilot Study
This pilot study will examine whether a single dental implant can be placed safely without giving antibiotics before or after surgery in patients with straightforward cases in Vietnam.
- Conditions
- Tooth Loss and Rehabillitation, Dental Implant Failure, Surgical Wound Infection
- Trial name
- NCT07920614
- Testing
- Single-Implant Placement Without Antibiotic Prophylaxis
- Where
- Vietnam
- Volunteers
- 39 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Obstructive Sleep Apnea Syndrome
Predictive Factors for Occlusal Changes in Obstructive Sleep Apnea Treatment With Mandibular Advancement Appliance
This research addresses obstructive sleep apnea syndrome (OSAS), affecting 6-12% of French adults, often treated with mandibular advancement devices (MADs).
- Trial name
- APNEAMOUVE (NCT06576310)
- Testing
- Mandibular Advancement Device
- Where
- France
- Volunteers
- 118 people
- Sponsor
- University Hospital, Toulouse
Tooth Loss, Dental Implant
Tissue Preservation in Immediate 1C Implants Using an Anatomical Prefabricated Healing Abutment
The goal of this clinical trial is to evaluate whether an anatomical prefabricated healing abutment (AHA) improves tissue preservation and clinical outcomes following immediate implant placement after tooth extraction in adults.
- Conditions
- Tooth Loss, Dental Implant, Clinical Trials, Randomized Controlled Trial
- Trial name
- Aharct (NCT07727980)
- Testing
- scannable anatomical healing abutment, Standard Healing Abutment for Dental Implants
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Illinois Chicago
Dental Anxiety, Dental Phobia
Virtual Reality Distraction for Dental Anxiety (RCT)
The aim of this randomized clinical trial is to verify the efficacy of VR immersion over a muted cartoon on a wall-mounted TV to decrease dental fear and anxiety of children undergoing dental procedures.
- Conditions
- Dental Anxiety, Dental Phobia, Dental Trauma, Dental Diseases
- Trial name
- NCT06182462
- Testing
- Virtual Reality Distraction, Dental Clinic's Standard Treatment
- Where
- Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Endosseous Dental Implant Failure, Accident Caused by Broken Ceramic
Full-Contour Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation Behavior
In patients who received a full-mouth implant-supported rehabilitation restored with CAD/CAM full-contour monolithic zirconia (FCMZ, without buccal ceramic veneer; veneering, if present, limited to the gingival area), what is the…
- Trial name
- FCMZ (NCT07876466)
- Testing
- Dental Implant, Monolithic Zirconia (FCMZ)
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Implantology Institute