Clinical trials: Dental Treatment
Temporomandibular Joint Dysfunction Syndrome, Tooth Injuries
Effectiveness of Three Oral Devices as Mouthguard in Electroconvulsive Therapy. Randomized Crossover Clinical Trial.
This observer-blind crossover intervention study aims to determine the most effective type of device as oral mouthguard in modified-Electroconvulsive Therapy (m-ECT) comparing three types of devices: standard, prefabricated and…
- Conditions
- Temporomandibular Joint Dysfunction Syndrome, Tooth Injuries, Dental Occlusion, Traumatic
- Trial name
- NCT02678715
- Testing
- Solubrux®, Customized Appliance, Somatics®
- Where
- Spain
- Volunteers
- 4 people
- Sponsor
- Eva Willaert Jiménez-Pajarero
Pulpitis, Healthy
Measurement of Pro-resolving Inflammation Biomarkers in Saliva, Gingival Fluid, and Dental Pulp in Patients With Symptomatic Pulpitis and Healthy Controls
This observational study aims to better understand inflammation inside the dental pulp (the inner tissue of the tooth) in patients with symptomatic pulpitis compared with healthy individuals.
- Trial name
- SMART-PULP (NCT07450235)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Université de Nantes
Dental Pulp Disorder
Monocentric Study and Prognostic of Treatments Endodontics of Teeth With Periapical Pathology Realized CSERD (Nantes University Hospital)
Endodontic therapy is to achieve the eviction of the inflamed or infected pulp and fill the canal opening with a hermetic sealing material.
- Trial name
- NCT02819258
- Testing
- Endodontic treatment
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Mucositis
Efficacy of 0.12% Chlorhexidine Gluconate for Peri-implant Mucositis
The purpose of this study is to analyze the efficacy of 0.12% chlorhexidine gluconate as a chemical adjuvant for the treatment of peri-implant mucositis, in a non-surgical treatment protocol with a six-month follow-up.
- Trial name
- NCT02605382
- Testing
- Chlorhexidine gluconate
- Volunteers
- 37 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Destructed Teeth Restored by Zirconia Crowns, Zirconia Crowns
Clinical Outcomes of Bonded Monolithic Translucent Zirconia Crowns Using Two Different Compositions of Self-adhesive Resin Cements
The aim of the present study is to evaluate the clinical outcomes (marginal discoloration, marginal adaptation, gingival health, debonding and patient satisfaction) of translucent zirconia crowns bonded by TheraCem (MDP, calcium…
- Conditions
- Destructed Teeth Restored by Zirconia Crowns, Zirconia Crowns, Decayed, Missing, and Filled Teeth, Tooth Discoloration
- Trial name
- NCT04875468
- Testing
- TheraCem self-adhesive resin cement, Multilink adhesive resin cement
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Diana Mostafa Habeb
Tooth Loss, Surface Treatment
Photofunctionalization and Hyaluronic Acid for Posterior Maxillary Implants
This randomized clinical trial evaluates the effect of UV photofunctionalization and hyaluronic acid on dental implants placed in the posterior maxilla. Clinical and radiographic outcomes will be assessed during follow-up
- Conditions
- Tooth Loss, Surface Treatment, Delayed Implant, Implant Placement
- Trial name
- PHOTOHA (NCT07700732)
- Testing
- Delayed dental implant placement without photofunctionalization., Delayed dental Implant photofunctionalization before placement, Delayed dental Implant photofunctionalization and hyaluronic acid application before placement.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
COVID-19 Respiratory Infection, Covid19
COVID-19 Vaccine Hesitancy and Dental Faculty Staff Members in Egypt
Healthcare workers (HCWs) play a vital role in determining the success of vaccination programs. Patient acceptance and vaccination rely greatly on the utilization and attitude of HCWs towards the vaccine, their attitude also…
- Conditions
- COVID-19 Respiratory Infection, Covid19, Vaccine Refusal
- Trial name
- NCT05009043
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mariam Ayman Amin Sharaf
Open Bite, Malocclusion Class I
Clinical Comparison of Clear Aligners and Fixed Appliances in Dental Anterior Open Bite
Dental anterior open bite is a challenging orthodontic condition with a high risk of relapse in adults. This randomized controlled clinical trial aims to compare the effectiveness and post-treatment stability of in-house clear…
- Trial name
- NCT07778108
- Testing
- In-House Clear Aligners, Fixed Orthodontic Appliances
- Volunteers
- 46 people
- Sponsor
- Sana'a University
Sensory Processing Disorder
Evaluating Sensory-Adapted Dental Care in Children With Sensory Processing Disorders
This clinical trial examines the efficacy of a Sensory-Adapted Dental Environment (SADE) in reducing anxiety and improving behavioral outcomes in children with sensory processing disorders during routine dental visits.
- Trial name
- NCT06411808
- Testing
- Sensory-Adapted Dental Environment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Peri-Implantitis, Surgery
Surgical Treatment of Peri-implantitis Using a Bone Substitute With or Without a Resorbable Collagen Membrane
The objective of the present randomized clinical trial will be to compare two surgical methods of treating peri-implantitis. This study will determine if surgical debridement of peri-implantitis bone defects, including air powder…
- Trial name
- NCT05699343
- Testing
- InterOss Collagen (Bone xenograft) and InterOss Collagen Guide (Collagen membrane), InterOss Collagen (Bone xenograft)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Andrea Ravida
Dental Caries in Children
Prevalence of Dental Caries Among a Group of Egyptian Children Using CAST Index
The aim of this study is to assess the prevalence of dental caries using CAST index among a group of Egyptian children in primary dentition stage.
- Trial name
- NCT03573180
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpal Necrosis
Triple Antibiotic Paste vs Simvastatin for Lesion Sterilization and Tissue Repair in Primary Molars.
This randomized, double-blinded, parallel-controlled clinical trial aims to compare the effectiveness of Triple Antibiotic Paste (TAP) and Simvastatin in Lesion Sterilization and Tissue Repair (LSTR) of primary molars with pulp…
- Trial name
- LSTR (NCT07264842)
- Testing
- Lesion Sterilization and Tissue Repair using Simvastatin., Lesion Sterilization and Tissue Repair using Triple Antibiotic Paste.
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Dental Anxiety
Augmented Reality Distraction for Reducing Pain in Pediatric Dental Procedures
This randomized controlled trial evaluates the effectiveness of augmented reality (AR) as a distraction technique to reduce procedural pain and anxiety in children aged 6-10 undergoing primary tooth extraction.
- Trial name
- AR (NCT06954883)
- Testing
- Augmented Reality Distraction, Standard Care (Tell-Show-Do Technique)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Periodontitis, Periodontal Pocket
Amoxicillin Plus Metronidazole in Periodontal Maintenance
Gum disease require a lifetime supportive periodontal care aiming at preventing additional inflammation and bone resorption. During this phase it is also relevant to keep germs under acceptable levels through proper daily hygiene…
- Trial name
- NCT05934227
- Testing
- Amoxicillin 500 milligrams capsules plus metronidazole 400 milligrams
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of Minas Gerais
Periodontitis, Periodontitis and Treatment Need
Dental Loupe Versus Dental Operating Microscope for Non-Surgical Periodontal Treatment
Periodontitis is a multifactorial, non-infectious disease that can lead to tooth loss if left untreated. Advanced stages of periodontitis can affect chewing ability, nutritional status, and quality of life.
- Conditions
- Periodontitis, Periodontitis and Treatment Need, Periodontal Disease, Periodontal Pocket
- Trial name
- NCT07822269
- Testing
- Mechanical debridement and dental plaque sample collection with dental loupe, Mechanical debridement and dental plaque sample collection with dental microscope
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Postoperative Dental Pain
Efficacy Of PF-05089771 In Treating Postoperative Dental Pain
The objective of this study is to evaluate the overall pain relief of a single dose of PF-05089771 against placebo following third molar extraction.
- Trial name
- NCT01529346
- Testing
- PF-05089771, Ibuprofen
- Where
- 3 sites in United States
- Volunteers
- 235 people
- Sponsor
- Pfizer
Dentin Caries
Evaluation of ART Restorations Using Two Different Bulk-Fill Restorative Materials in Primary Molars
The aim of this clinical study is to evaluate the success of two different bulk-fill restorative materials applied to teeth restored with atraumatic treatment at 3, 6, and 12-month follow-ups.
- Trial name
- NCT06771362
- Testing
- ART with Bulk-Fill composite, ART with Glass Ionomer
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people
- Sponsor
- Çanakkale Onsekiz Mart University
Endodontically Treated Teeth, Post Operative Pain
Bioceramics Pain Control
Postoperative pain in endodontic retreatment cases presents a challenge to any endodontist. Tricalcium silicate materials as mineral trioxide aggregate (MTA) and bioceramics have shown favorable periapical tissue reactions and…
- Trial name
- NCT05399303
- Testing
- obturation
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Misr International University
Hypnotherapy, Virtual Reality
Dental Anxiety During Restorative Dental Treatment
Anxiety refers to behavioural disorders associated with excessive fear and anxiety. Dental anxiety refers to excessive fear and anxiety at the thought of going to the dentist.
- Conditions
- Hypnotherapy, Virtual Reality, Mindfulness
- Trial name
- DADRDT (NCT06629870)
- Testing
- virtual reality, control group, hypnotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Dental Caries
Er:YAG Laser for Dental Cavity Preparation
The goal of this clinical trial is to compare Er:YAG laser cavity preparation with conventional rotary instruments in adults who have permanent premolars planned for extraction as part of orthodontic treatment.
- Trial name
- NCT07831720
- Testing
- Er:YAG Laser, Conventional Rotary Cavity Preparation
- Where
- Vietnam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ho Chi Minh City Odonto-Stomatology Hospital
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