Clinical trials: Dental Treatment
Dental Caries
Impact of Atraumatic Restorative Treatment and Oral Health Promotion on Psychological and Salivary Aspects of Children
This study evaluated the impact of atraumatic restorative treatment associated with oral health educational strategy on dental anxiety, oral health-related quality of life and salivary biochemical and microbiological…
- Trial name
- NCT03100773
- Testing
- Oral health educational strategy, Atraumatic Restorative Treatment
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dental Caries
Traditional vs. Minimally Invasive Decay Treatments in Primary Molars: An 18-month Split-mouth Randomized Study
The goal of this clinical trial is to compare the 18-month clinical success rates of three caries management approaches in primary molars of 60 healthy children aged 4-8 years attending the Department of Pediatric Dentistry at…
- Trial name
- MiCRO-PM (NCT07447583)
- Testing
- Hall Technique, Silver diamine Fluoride 38%, Compomer Restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Dental Caries, Dental Atraumatic Restorative Treatment
Oral Health and Its Relation to Development and Well-being of Schoolchildren Before and After Restorative Treatments
The present study aims evaluate the oral health conditions of schoolchildren and its relation to growth, development and well-being.
- Conditions
- Dental Caries, Dental Atraumatic Restorative Treatment, Oral Health
- Trial name
- NCT02754466
- Testing
- Subjective vs objective criteria in selective excavation, Glass-ionomer vs Bulk fill composites in the ART approach
- Where
- Brazil
- Volunteers
- 270 people
- Sponsor
- University of Brasilia
Pain, Postoperative, Quality of Life
Efficacy of Two Local Anesthetics on Quality of Life After Endodontic Treatment
In this randomized controlled double-blinded study, subjects will be assigned to one of two study groups to either be anesthetized with Bupivacaine or Lidocaine prior to needed treatment of pulpectomy/endodontic debridement on a…
- Trial name
- B-OHIP14 (NCT04787731)
- Testing
- Bupivacaine Local Anesthetic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Endodontically Treated Teeth, Tooth Fractures
Prefabricated Endodontic Posts: Glass Fiber Versus Titanium - A Randomized Controlled Pilot- Trial
A randomized parallel-group clinical pilot study was designed to evaluate the impact of glass fiber reinforced composite posts compared to prefabricated titanium posts on long term survival of adhesively restored endodontically…
- Trial name
- NCT01520766
- Testing
- prefabricated titanium post, prefabricated glass fiber reinforced composite post
- Where
- Germany
- Volunteers
- 91 people
- Sponsor
- Charite University, Berlin, Germany
Malocclusion, Angle Class I, Malocclusion; Displaced or Missing Teeth
Comparison Between Clear Aligners and Traditional Fixed Appliances in the Treatment of Four-premolar-extraction Cases
Patients who have severe crowding that require four premolars extraction will be treated in this study. The efficacy of the clear aligners and vestibular fixed appliances will be assessed.
- Conditions
- Malocclusion, Angle Class I, Malocclusion; Displaced or Missing Teeth, Crowding
- Trial name
- NCT03645356
- Testing
- Fixed Appliances, Clear Aligners
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Dental Caries, Endodontically Treated Teeth
Clinical Evaluation of Posterior Indirect Adhesive Restorations
Clinical performance of indirect adhesive restorations - onlays, overlays- luted with light-cured composite resin will be evaluated over three years.
- Conditions
- Dental Caries, Endodontically Treated Teeth, Dental Restoration Failure of Marginal Integrity, Wear, Occlusal
- Trial name
- NCT04293770
- Testing
- Indirect adhesive restoration of posterior teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Okan University
Maxillary Anterior Diastema
Effect of Direct Anterior Diastema Closure on Quality of Life and Dental Anxiety
The aim of this study is to evaluate the effects of non-invasive direct anterior diastema closure on dental anxiety and oral health-related quality of life in adults with maxillary anterior diastema.
- Trial name
- NCT07480551
- Testing
- Direct Composite Resin Restoration for Anterior Diastema Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Recep Tayyip Erdogan University
Peri-Implantitis
Regenerative Surgical Treatment of Peri-implantitis Using Nanobone With or Without Simvastatin
The aim of this study was to evaluate the effect of using a synthetic bone substitute with or without simvastatin on regenerative surgical treatment of bone defects associated with peri-implantitis in a 6- months randomized…
- Trial name
- RAS (NCT04559841)
- Testing
- bone substitute; NanoBone®
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Reham Lotfy Aggour
Dental Caries in Children
Comparison Between Amalgam and Hall Technique in Treatment of Carious Primary Teeth
compare between amalgam restoration and hall technique for treatment of decayed primary molars and intervention treatment for decayed primary molars in children, age 3-5 years using split mouth technique in the same child…
- Trial name
- NCT06924203
- Testing
- AmaIgam, Stainless steel
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Suez Canal University
Endodontically Treated Teeth
Long-term Performance and Safety of Biodentine™ in Patients Treated for Endodontic Indications
In this observational, retro-prospective, and multicenter PMCF clinical investigation, Biodentine™, an active dentine substitute for professional dental use only, is evaluated at 10 years post-treatment, in its endodontic…
- Trial name
- NCT05084742
- Testing
- Biodentine™
- Where
- 6 sites in France
- Volunteers
- 145 people
- Sponsor
- Septodont
Dental Caries
Pre-etching of Dentin Before Restorations With High Viscosity Glass Ionomer Cement
The objective of this randomized clinical trial is to evaluate the survival of restoration with high viscosity glass ionomer cement (HVGIC) with pre-etching with polyacrilic acid compared with no pre-etching in order to treat…
- Trial name
- CEPECO4 (NCT03785769)
- Testing
- HVGIC restoration with pre-etching, HVGIC restoration with non pre-etching
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Ibirapuera
Dental Caries in Children
Pandemic-adapted Caries Care Multicentre Single-group Interventional Study
The current understanding of dental caries has not been completely transferred into the clinical practice to control caries lesion progression (severity / activity) and the individual risk of caries.
- Trial name
- NCT04666597
- Testing
- Modified CariesCare International management
- Where
- 21 sites in United States, Argentina and 11 more
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
Behavior, Dental Anxiety
Parental Affect in Dental Procedures
Background: To evaluate the effect of the anxiety of a parent accompanying a child on the child's anxiety during treatment. Methods: Parents of 160 patients (4-8 years old) were divided into two groups anxious and non-anxious.
- Trial name
- NCT04636580
- Testing
- parent accompanying the child during treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Uşak University
Fluorosis, Dental, Fluorosis
Design of a Multicomponent Intervention to Reduce the Risk of Exposure Fluorine
Introduction Systemic exposure to fluoride is a significant challenge for global public health; this is because although fluoride prevents dental caries, prolonged exposure to high concentrations can cause adverse effects on…
- Trial name
- NCT07232888
- Testing
- multicomponent intervention, Conventional intervention
- Where
- Colombia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio Nariño
Autism Spectrum Disorder
A Protocol to Streamline Dental Care in Autistic Children
The investigators aim at creating a dedicated pathway to allow accessibility to dental care for ASD children within a hospital Dentistry Department, in order to diminish the need for general anesthesia.
- Trial name
- DentAutism (NCT05553262)
- Testing
- Behavioral support
- Where
- Italy
- Volunteers
- 170 people
- Sponsor
- University of Padova
Dental Caries
Resin Infiltration to Arrest Early Tooth Decay
The purpose of this study is to determine whether lesion infiltration is an effective management strategy to arrest early tooth decay.
- Trial name
- NCT01584024
- Testing
- Resin infiltration
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Michigan
Head and Neck Cancer, Dental Disease
Observational Study of Dental Outcomes in Head and Neck Cancer Patients
The purpose of this study is to measure the two-year rate of tooth loss in patients who have received external beam radiation therapy with curative intent for head and neck cancer.
- Conditions
- Head and Neck Cancer, Dental Disease, Xerostomia, Osteoradionecrosis
- Trial name
- ORARAD (NCT02057510)
- Where
- 6 sites in United States
- Volunteers
- 613 people
- Sponsor
- Wake Forest University Health Sciences
Early Childhood Caries
Effectiveness of Dental Caries Arrest Treatment in Primary Teeth Using AgNO3 Followed by NaF Varnish
Aim: This randomised controlled trial will systematically compare the efficacy of a 25% AgNO3 solution followed by 5% NaF varnish with that of a 38% SDF solution in arresting caries teeth among preschool children when applied at…
- Trial name
- NCT02019160
- Testing
- 25% AgNO3 solution followed by 5% NaF varnish
- Where
- China
- Volunteers
- 1,070 people
- Sponsor
- The University of Hong Kong
Orthodontic Appliance Complication, Plaque, Dental
Regular Home Use of Dual-light Photodynamic Therapy on Oral Health in Adolescents Undergoing Fixed Orthodontic Treatment
This study is designed to determine the efficacy of the Lumoral method on oral health in adolescents undergoing fixed orthodontic treatment.
- Conditions
- Orthodontic Appliance Complication, Plaque, Dental, Gingival Inflammation
- Trial name
- NCT05825742
- Testing
- Lumoral Treatment, Standard oral health instructions
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Koite Health Oy
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